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Volumn 25, Issue 2, 2012, Pages 108-117

The clinical benefit and safety of current and future assisted reproductive technology

Author keywords

assisted reproductive technology; embryo selection; IVF; preimplantation genetic screening; sperm DNA damage; time lapse imaging

Indexed keywords

AMINO ACID ANALYSIS; DNA DAMAGE; DNA DETERMINATION; FERTILIZATION IN VITRO; GENE THERAPY; GENETIC SCREENING; HUMAN; INFERTILITY THERAPY; INTRACYTOPLASMIC SPERM INJECTION; MEDICAL ETHICS; MEDICAL RESEARCH; MEDICAL TECHNOLOGY; METABOLOMICS; PREIMPLANTATION EMBRYO; REPRODUCTION; REVIEW; RISK ASSESSMENT; TRANSPLANTATION;

EID: 84864485449     PISSN: 14726483     EISSN: 14726491     Source Type: Journal    
DOI: 10.1016/j.rbmo.2012.04.009     Document Type: Review
Times cited : (10)

References (102)
  • 2
    • 78650910257 scopus 로고    scopus 로고
    • Redox regulation of human sperm function: From the physiological control of sperm capacitation to the etiology of infertility and DNA damage in the germ line
    • R.J. Aitken, and B.J. Curry Redox regulation of human sperm function: from the physiological control of sperm capacitation to the etiology of infertility and DNA damage in the germ line Antioxidants and Redox Signaling 14 3 2011 367 381
    • (2011) Antioxidants and Redox Signaling , vol.14 , Issue.3 , pp. 367-381
    • Aitken, R.J.1    Curry, B.J.2
  • 4
    • 0034758449 scopus 로고    scopus 로고
    • Oxidative stress, DNA damage and the y chromosome
    • R.J. Aitken, and C. Krausz Oxidative stress, DNA damage and the Y chromosome Reproduction 122 4 2001 497 506
    • (2001) Reproduction , vol.122 , Issue.4 , pp. 497-506
    • Aitken, R.J.1    Krausz, C.2
  • 5
    • 79957533987 scopus 로고    scopus 로고
    • The Istanbul consensus workshop on embryo assessment: Proceedings of an expert meeting
    • Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology
    • Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting Human Reproduction 26 2011 1270 1283
    • (2011) Human Reproduction , vol.26 , pp. 1270-1283
  • 12
    • 0347480530 scopus 로고    scopus 로고
    • Pregnancy rates are higher with intracytoplasmic morphologically selected sperm injection than with conventional intracytoplasmic injection
    • B. Bartoov, A. Berkovitz, F. Eltes, A. Kogosovsky, A. Yagoda, H. Lederman, S. Artzi, M. Gross, and Y. Barak Pregnancy rates are higher with intracytoplasmic morphologically selected sperm injection than with conventional intracytoplasmic injection Fertility and Sterility 80 2003 1413 1419
    • (2003) Fertility and Sterility , vol.80 , pp. 1413-1419
    • Bartoov, B.1    Berkovitz, A.2    Eltes, F.3    Kogosovsky, A.4    Yagoda, A.5    Lederman, H.6    Artzi, S.7    Gross, M.8    Barak, Y.9
  • 13
    • 12444318663 scopus 로고    scopus 로고
    • The morphological normalcy of the sperm nucleus and pregnancy rate of intracytoplasmic injection with morphologically selected sperm
    • A. Berkovitz, F. Eltes, S. Yaari, N. Katz, I. Barr, A. Fishman, and B. Bartoov The morphological normalcy of the sperm nucleus and pregnancy rate of intracytoplasmic injection with morphologically selected sperm Human Reproduction 20 2005 185
    • (2005) Human Reproduction , vol.20 , pp. 185
    • Berkovitz, A.1    Eltes, F.2    Yaari, S.3    Katz, N.4    Barr, I.5    Fishman, A.6    Bartoov, B.7
  • 14
    • 33745857346 scopus 로고    scopus 로고
    • Does the presence of nuclear vacuoles in human sperm selected for ICSI affect pregnancy outcome?
    • A. Berkovitz, F. Eltes, A. Ellenbogen, S. Peer, D. Feldberg, and B. Bartoov Does the presence of nuclear vacuoles in human sperm selected for ICSI affect pregnancy outcome? Human Reproduction 21 2006 1787
    • (2006) Human Reproduction , vol.21 , pp. 1787
    • Berkovitz, A.1    Eltes, F.2    Ellenbogen, A.3    Peer, S.4    Feldberg, D.5    Bartoov, B.6
  • 17
    • 58249110516 scopus 로고    scopus 로고
    • Metabolomics and its application for non-invasive embryo assessment in IVF
    • L. Botros, D. Sakkas, and E. Seli Metabolomics and its application for non-invasive embryo assessment in IVF Molecular Human Reproduction 14 2008 679
    • (2008) Molecular Human Reproduction , vol.14 , pp. 679
    • Botros, L.1    Sakkas, D.2    Seli, E.3
  • 21
    • 78650996550 scopus 로고    scopus 로고
    • Sperm chromatin structure assay (SCSA): A tool in diagnosis and treatment of infertility
    • M. Bungum, L. Bungum, and A. Giwercman Sperm chromatin structure assay (SCSA): a tool in diagnosis and treatment of infertility Asian Journal of Andrology 13 2011 69 75
    • (2011) Asian Journal of Andrology , vol.13 , pp. 69-75
    • Bungum, M.1    Bungum, L.2    Giwercman, A.3
  • 22
    • 61449239108 scopus 로고    scopus 로고
    • Predictive value of semen parameters in in vitro fertilisation pregnancy outcome
    • X. Chen, W. Zhang, Y. Luo, X. Long, and X. Sun Predictive value of semen parameters in in vitro fertilisation pregnancy outcome Andrologia 41 2009 111 117
    • (2009) Andrologia , vol.41 , pp. 111-117
    • Chen, X.1    Zhang, W.2    Luo, Y.3    Long, X.4    Sun, X.5
  • 24
    • 41749087618 scopus 로고    scopus 로고
    • Do sperm DNA integrity tests predict pregnancy with in vitro fertilization?
    • J.A. Collins, K.T. Barnhart, and P.N. Schlegel Do sperm DNA integrity tests predict pregnancy with in vitro fertilization? Fertility and Sterility 89 2008 823 831
    • (2008) Fertility and Sterility , vol.89 , pp. 823-831
    • Collins, J.A.1    Barnhart, K.T.2    Schlegel, P.N.3
  • 27
    • 38049042856 scopus 로고    scopus 로고
    • Fertility preservation: Successful transplantation of cryopreserved ovarian tissue in a young patient previously treated for Hodgkin's disease
    • I. Demeestere, P. Simon, S. Emiliani, A. Delbaere, and Y. Englert Fertility preservation: successful transplantation of cryopreserved ovarian tissue in a young patient previously treated for Hodgkin's disease The Oncologist 12 2007 1437
    • (2007) The Oncologist , vol.12 , pp. 1437
    • Demeestere, I.1    Simon, P.2    Emiliani, S.3    Delbaere, A.4    Englert, Y.5
  • 29
    • 33747877744 scopus 로고    scopus 로고
    • Intra-individual variation in sperm chromatin structure assay parameters in men from infertile couples: Clinical implications
    • J. Erenpreiss, M. Bungum, M. Spano, S. Elzanaty, J. Orbidans, and A. Giwercman Intra-individual variation in sperm chromatin structure assay parameters in men from infertile couples: clinical implications Human Reproduction 21 2006 2061
    • (2006) Human Reproduction , vol.21 , pp. 2061
    • Erenpreiss, J.1    Bungum, M.2    Spano, M.3    Elzanaty, S.4    Orbidans, J.5    Giwercman, A.6
  • 30
    • 33645772944 scopus 로고    scopus 로고
    • Meta-analysis of sperm DNA fragmentation using the sperm chromatin structure assay
    • D. Evenson, and R. Wixon Meta-analysis of sperm DNA fragmentation using the sperm chromatin structure assay Reproductive Biomedicine Online 12 2006 466 472
    • (2006) Reproductive Biomedicine Online , vol.12 , pp. 466-472
    • Evenson, D.1    Wixon, R.2
  • 31
    • 0019296108 scopus 로고
    • Relation of mammalian sperm chromatin heterogeneity to fertility
    • D.P. Evenson, Z. Darzynkiewicz, and M.R. Melamed Relation of mammalian sperm chromatin heterogeneity to fertility Science 210 1980 1131
    • (1980) Science , vol.210 , pp. 1131
    • Evenson, D.P.1    Darzynkiewicz, Z.2    Melamed, M.R.3
  • 36
    • 84864437788 scopus 로고    scopus 로고
    • Morphological nuclear integrity of sperm cells is associated with preimplantation genetic aneuploidy screening cycle outcomes
    • R.C.S. Figueira, D. Braga, A.S. Setti, A. Iaconelli Jr., and E. Borges Jr. Morphological nuclear integrity of sperm cells is associated with preimplantation genetic aneuploidy screening cycle outcomes Fertility and Sterility 2010
    • (2010) Fertility and Sterility
    • Figueira, R.C.S.1    Braga, D.2    Setti, A.S.3    Iaconelli, Jr.A.4    Borges, Jr.E.5
  • 38
    • 0346562866 scopus 로고    scopus 로고
    • Derivation of embryonic germ cells and male gametes from embryonic stem cells
    • N. Geijsen, M. Horoschak, K. Kim, J. Gribnau, K. Eggan, and G.Q. Daley Derivation of embryonic germ cells and male gametes from embryonic stem cells Nature 427 2003 148 154
    • (2003) Nature , vol.427 , pp. 148-154
    • Geijsen, N.1    Horoschak, M.2    Kim, K.3    Gribnau, J.4    Eggan, K.5    Daley, G.Q.6
  • 39
    • 84864424664 scopus 로고    scopus 로고
    • An experimental protocol for fertility preservation in prepubertal boys recently diagnosed with cancer: A report of acceptability and safety
    • J.P. Ginsberg, C.A. Carlson, K. Lin, W.L. Hobbie, E. Wigo, X. Wu, R.L. Brinster, and T.F. Kolon An experimental protocol for fertility preservation in prepubertal boys recently diagnosed with cancer: a report of acceptability and safety Human Reproduction 2009
    • (2009) Human Reproduction
    • Ginsberg, J.P.1    Carlson, C.A.2    Lin, K.3    Hobbie, W.L.4    Wigo, E.5    Wu, X.6    Brinster, R.L.7    Kolon, T.F.8
  • 40
    • 0027217458 scopus 로고
    • Presence of DNA strand breaks and increased sensitivity of DNA in situ to denaturation in abnormal human sperm cells: Analogy to apoptosis of somatic cells
    • W. Gorczyca, F. Traganos, H. Jesionowska, and Z. Darzynkiewicz Presence of DNA strand breaks and increased sensitivity of DNA in situ to denaturation in abnormal human sperm cells: analogy to apoptosis of somatic cells Experimental Cell Research 207 1993 202 205
    • (1993) Experimental Cell Research , vol.207 , pp. 202-205
    • Gorczyca, W.1    Traganos, F.2    Jesionowska, H.3    Darzynkiewicz, Z.4
  • 43
    • 77956188325 scopus 로고    scopus 로고
    • The use of arrays in preimplantation genetic diagnosis and screening
    • J.C. Harper, and G. Harton The use of arrays in preimplantation genetic diagnosis and screening Fertility and Sterility 94 2010 1173 1177
    • (2010) Fertility and Sterility , vol.94 , pp. 1173-1177
    • Harper, J.C.1    Harton, G.2
  • 46
    • 84855890370 scopus 로고    scopus 로고
    • When and how should new technology be introduced into the IVF laboratory?
    • J. Harper, M.C. Magli, K. Lundin, C.L.R. Barratt, and D.R. Brison When and how should new technology be introduced into the IVF laboratory? Human Reproduction 27 2 2012 303 313
    • (2012) Human Reproduction , vol.27 , Issue.2 , pp. 303-313
    • Harper, J.1    Magli, M.C.2    Lundin, K.3    Barratt, C.L.R.4    Brison, D.R.5
  • 48
    • 58149088047 scopus 로고    scopus 로고
    • Successful pregnancies after application of array-comparative genomic hybridization in PGS-aneuploidy screening
    • A. Hellani, K. Abu-Amero, J. Azouri, and S. El-Akoum Successful pregnancies after application of array-comparative genomic hybridization in PGS-aneuploidy screening Reproductive Biomedicine Online 17 2008 841 847
    • (2008) Reproductive Biomedicine Online , vol.17 , pp. 841-847
    • Hellani, A.1    Abu-Amero, K.2    Azouri, J.3    El-Akoum, S.4
  • 49
    • 77957301532 scopus 로고    scopus 로고
    • TUNEL assay and SCSA determine different aspects of sperm DNA damage
    • R. Henkel, C.F. Hoogendijk, P.J.D. Bouic, and T.F. Kruger TUNEL assay and SCSA determine different aspects of sperm DNA damage Andrologia 42 2010 305 313
    • (2010) Andrologia , vol.42 , pp. 305-313
    • Henkel, R.1    Hoogendijk, C.F.2    Bouic, P.J.D.3    Kruger, T.F.4
  • 52
    • 44949236104 scopus 로고    scopus 로고
    • What next for preimplantation genetic screening (PGS)? Experience with blastocyst biopsy and testing for aneuploidy
    • R.P.S. Jansen, M.C. Bowman, K.A. de Boer, D.A. Leigh, D.B. Lieberman, and S.J. McArthur What next for preimplantation genetic screening (PGS)? Experience with blastocyst biopsy and testing for aneuploidy Human Reproduction 23 2008 1476 1478
    • (2008) Human Reproduction , vol.23 , pp. 1476-1478
    • Jansen, R.P.S.1    Bowman, M.C.2    De Boer, K.A.3    Leigh, D.A.4    Lieberman, D.B.5    McArthur, S.J.6
  • 55
    • 0141885249 scopus 로고    scopus 로고
    • Effects of adenovirus mediated gene transfer to mouse testis in vivo on spermatogenesis and next generation
    • Y. Kojima, S. Sasaki, Y. Umemoto, Y. Hashimoto, Y. Hayashi, and K. Kohri Effects of adenovirus mediated gene transfer to mouse testis in vivo on spermatogenesis and next generation The Journal of Urology 170 2003 2109 2114
    • (2003) The Journal of Urology , vol.170 , pp. 2109-2114
    • Kojima, Y.1    Sasaki, S.2    Umemoto, Y.3    Hashimoto, Y.4    Hayashi, Y.5    Kohri, K.6
  • 59
    • 55549115368 scopus 로고    scopus 로고
    • The biology of infertility: Research advances and clinical challenges
    • M.M. Matzuk, and D.J. Lamb The biology of infertility: research advances and clinical challenges Nature Medicine 14 2008 1197 1213
    • (2008) Nature Medicine , vol.14 , pp. 1197-1213
    • Matzuk, M.M.1    Lamb, D.J.2
  • 61
    • 52949141134 scopus 로고    scopus 로고
    • Preimplantation genetic screening to improve in vitro fertilization pregnancy rates: A prospective randomized controlled trial
    • J.E. Mersereau, E. Pergament, X. Zhang, and M.P. Milad Preimplantation genetic screening to improve in vitro fertilization pregnancy rates: a prospective randomized controlled trial Fertility and Sterility 90 2008 1287 1289
    • (2008) Fertility and Sterility , vol.90 , pp. 1287-1289
    • Mersereau, J.E.1    Pergament, E.2    Zhang, X.3    Milad, M.P.4
  • 67
    • 51349086778 scopus 로고    scopus 로고
    • Gene therapy and intracytoplasmatic sperm injection (ICSI) - A review
    • J. Navarro, R. Risco, M. Toschi, and G. Schattman Gene therapy and intracytoplasmatic sperm injection (ICSI) - A review Placenta 29 2008 193 199
    • (2008) Placenta , vol.29 , pp. 193-199
    • Navarro, J.1    Risco, R.2    Toschi, M.3    Schattman, G.4
  • 69
    • 34848919748 scopus 로고    scopus 로고
    • Light intensity and wavelength during embryo manipulation are important factors for maintaining viability of preimplantation embryos in vitro
    • S.J. Oh, S.P. Gong, S.T. Lee, E.J. Lee, and J.M. Lim Light intensity and wavelength during embryo manipulation are important factors for maintaining viability of preimplantation embryos in vitro Fertility and Sterility 88 2007 1150 1157
    • (2007) Fertility and Sterility , vol.88 , pp. 1150-1157
    • Oh, S.J.1    Gong, S.P.2    Lee, S.T.3    Lee, E.J.4    Lim, J.M.5
  • 71
    • 65649126708 scopus 로고    scopus 로고
    • Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells
    • T.S. Park, Z. Galic, A.E. Conway, A. Lindgren, B.J. van Handel, M. Magnusson, L. Richter, M.A. Teitell, H.K.A. Mikkola, and W.E. Lowry Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells Stem Cells 27 2009 783 795
    • (2009) Stem Cells , vol.27 , pp. 783-795
    • Park, T.S.1    Galic, Z.2    Conway, A.E.3    Lindgren, A.4    Van Handel, B.J.5    Magnusson, M.6    Richter, L.7    Teitell, M.A.8    Mikkola, H.K.A.9    Lowry, W.E.10
  • 74
    • 77049084953 scopus 로고    scopus 로고
    • Sperm DNA fragmentation: Mechanisms of origin, impact on reproductive outcome, and analysis
    • D. Sakkas, and J.G. Alvarez Sperm DNA fragmentation: mechanisms of origin, impact on reproductive outcome, and analysis Fertility and Sterility 93 2010 1027 1036
    • (2010) Fertility and Sterility , vol.93 , pp. 1027-1036
    • Sakkas, D.1    Alvarez, J.G.2
  • 75
    • 67649099954 scopus 로고    scopus 로고
    • Preimplantation aneuploidy testing for infertile patients of advanced maternal age: A randomized prospective trial
    • W.B. Schoolcraft, M.G. Katz-Jaffe, J. Stevens, M. Rawlins, and S. Munne Preimplantation aneuploidy testing for infertile patients of advanced maternal age: a randomized prospective trial Fertility and Sterility 92 2009 157 162
    • (2009) Fertility and Sterility , vol.92 , pp. 157-162
    • Schoolcraft, W.B.1    Katz-Jaffe, M.G.2    Stevens, J.3    Rawlins, M.4    Munne, S.5
  • 76
    • 45849120634 scopus 로고    scopus 로고
    • Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: A prospective blinded pilot study
    • R. Scott, E. Seli, K. Miller, D. Sakkas, K. Scott, and D.H. Burns Noninvasive metabolomic profiling of human embryo culture media using Raman spectroscopy predicts embryonic reproductive potential: a prospective blinded pilot study Fertility and Sterility 90 2008 77 83
    • (2008) Fertility and Sterility , vol.90 , pp. 77-83
    • Scott, R.1    Seli, E.2    Miller, K.3    Sakkas, D.4    Scott, K.5    Burns, D.H.6
  • 77
    • 35648974233 scopus 로고    scopus 로고
    • Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization
    • E. Seli, D. Sakkas, R. Scott, S.C. Kwok, S.M. Rosendahl, and D.H. Burns Noninvasive metabolomic profiling of embryo culture media using Raman and near-infrared spectroscopy correlates with reproductive potential of embryos in women undergoing in vitro fertilization Fertility and Sterility 88 2007 1350 1357
    • (2007) Fertility and Sterility , vol.88 , pp. 1350-1357
    • Seli, E.1    Sakkas, D.2    Scott, R.3    Kwok, S.C.4    Rosendahl, S.M.5    Burns, D.H.6
  • 78
    • 77955139167 scopus 로고    scopus 로고
    • OMICS in assisted reproduction: Possibilities and pitfalls
    • E. Seli, C. Robert, and M.A. Sirard OMICS in assisted reproduction: possibilities and pitfalls Molecular Human Reproduction 16 2010 513
    • (2010) Molecular Human Reproduction , vol.16 , pp. 513
    • Seli, E.1    Robert, C.2    Sirard, M.A.3
  • 79
    • 77953709625 scopus 로고    scopus 로고
    • Noninvasive metabolomic profiling as an adjunct to morphology for noninvasive embryo assessment in women undergoing single embryo transfer
    • E. Seli, C.G. Vergouw, H. Morita, L. Botros, P. Roos, C.B. Lambalk, N. Yamashita, O. Kato, and D. Sakkas Noninvasive metabolomic profiling as an adjunct to morphology for noninvasive embryo assessment in women undergoing single embryo transfer Fertility and Sterility 94 2010 535 542
    • (2010) Fertility and Sterility , vol.94 , pp. 535-542
    • Seli, E.1    Vergouw, C.G.2    Morita, H.3    Botros, L.4    Roos, P.5    Lambalk, C.B.6    Yamashita, N.7    Kato, O.8    Sakkas, D.9
  • 82
    • 77954105470 scopus 로고    scopus 로고
    • Preimplantation genetic diagnosis at 20 years
    • J.L. Simpson Preimplantation genetic diagnosis at 20 years Prenatal Diagnosis 30 2010 682 695
    • (2010) Prenatal Diagnosis , vol.30 , pp. 682-695
    • Simpson, J.L.1
  • 84
    • 11144305136 scopus 로고    scopus 로고
    • Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: A prospective randomized controlled trial
    • C. Staessen, P. Platteau, E. van Assche, A. Michiels, H. Tournaye, M. Camus, P. Devroey, I. Liebaers, and A. van Steirteghem Comparison of blastocyst transfer with or without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomized controlled trial Human Reproduction 19 2004 2849 2858
    • (2004) Human Reproduction , vol.19 , pp. 2849-2858
    • Staessen, C.1    Platteau, P.2    Van Assche, E.3    Michiels, A.4    Tournaye, H.5    Camus, M.6    Devroey, P.7    Liebaers, I.8    Van Steirteghem, A.9
  • 85
    • 56749175407 scopus 로고    scopus 로고
    • Preimplantation genetic screening does not improve delivery rate in women under the age of 36 following single-embryo transfer
    • C. Staessen, W. Verpoest, P. Donoso, P. Haentjens, J. van der Elst, I. Liebaers, and P. Devroey Preimplantation genetic screening does not improve delivery rate in women under the age of 36 following single-embryo transfer Human Reproduction 23 2008 2818 2825
    • (2008) Human Reproduction , vol.23 , pp. 2818-2825
    • Staessen, C.1    Verpoest, W.2    Donoso, P.3    Haentjens, P.4    Van Der Elst, J.5    Liebaers, I.6    Devroey, P.7
  • 86
    • 0018091794 scopus 로고
    • Birth after the reimplantation of a human embryo
    • P.C. Steptoe, and R.G. Edwards Birth after the reimplantation of a human embryo Lancet 2 1978 366
    • (1978) Lancet , vol.2 , pp. 366
    • Steptoe, P.C.1    Edwards, R.G.2
  • 87
    • 33845594760 scopus 로고    scopus 로고
    • Is aneuploidy screening for patients aged 35 or over beneficial? A prospective randomized trial
    • J. Stevens, P. Wale, E.S. Surrey, W.B. Schoolcraft, and D.K. Gardner Is aneuploidy screening for patients aged 35 or over beneficial? A prospective randomized trial Fertility and Sterility 82 2004 S249
    • (2004) Fertility and Sterility , vol.82 , pp. 249
    • Stevens, J.1    Wale, P.2    Surrey, E.S.3    Schoolcraft, W.B.4    Gardner, D.K.5
  • 90
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • K. Takahashi, K. Tanabe, M. Ohnuki, M. Narita, T. Ichisaka, K. Tomoda, and S. Yamanaka Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 2007 861 872
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6    Yamanaka, S.7
  • 96
    • 44949262024 scopus 로고    scopus 로고
    • Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: A novel, non-invasive method for embryo selection
    • C.G. Vergouw, L.L. Botros, P. Roos, J.W. Lens, R. Schats, P.G.A. Hompes, D.H. Burns, and C.B. Lambalk Metabolomic profiling by near-infrared spectroscopy as a tool to assess embryo viability: a novel, non-invasive method for embryo selection Human Reproduction 23 2008 1499
    • (2008) Human Reproduction , vol.23 , pp. 1499
    • Vergouw, C.G.1    Botros, L.L.2    Roos, P.3    Lens, J.W.4    Schats, R.5    Hompes, P.G.A.6    Burns, D.H.7    Lambalk, C.B.8
  • 97
    • 79959771330 scopus 로고    scopus 로고
    • Intracytoplasmic injection of morphologically selected spermatozoa (IMSI) improves outcome after assisted reproduction by deselecting physiologically poor quality spermatozoa
    • Epub ahead of print
    • Wilding, M., Coppola, G., di Matteo, L., Palagiano, A., Fusco, E. and Dale, B. (2010) Intracytoplasmic injection of morphologically selected spermatozoa (IMSI) improves outcome after assisted reproduction by deselecting physiologically poor quality spermatozoa. Journal of Assisted Reproduction and Genetics, Epub ahead of print.
    • (2010) Journal of Assisted Reproduction and Genetics
    • Wilding, M.1    Coppola, G.2    Di Matteo, L.3    Palagiano, A.4    Fusco, E.5    Dale, B.6
  • 98
    • 37349098129 scopus 로고    scopus 로고
    • The impact of high-magnification evaluation of sperm on ART outcome
    • C. Wittemer, A. Pujol, H. Boughali, and S. Viville The impact of high-magnification evaluation of sperm on ART outcome Human Reproduction 21 2006 I59 I60
    • (2006) Human Reproduction , vol.21
    • Wittemer, C.1    Pujol, A.2    Boughali, H.3    Viville, S.4
  • 99
    • 77957938684 scopus 로고    scopus 로고
    • Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage
    • C.C. Wong, K.E. Loewke, N.L. Bossert, B. Behr, C.J. de Jonge, T.M. Baer, and R.A.R. Pera Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage Nature Biotechnology 28 2010 1115 1121
    • (2010) Nature Biotechnology , vol.28 , pp. 1115-1121
    • Wong, C.C.1    Loewke, K.E.2    Bossert, N.L.3    Behr, B.4    De Jonge, C.J.5    Baer, T.M.6    Pera, R.A.R.7
  • 101
    • 78651379641 scopus 로고    scopus 로고
    • Are sperm chromatin and DNA defects relevant in the clinic?
    • A. Zini Are sperm chromatin and DNA defects relevant in the clinic? Systems Biology in Reproductive Medicine 2011 78 85
    • (2011) Systems Biology in Reproductive Medicine , pp. 78-85
    • Zini, A.1
  • 102
    • 65549116879 scopus 로고    scopus 로고
    • Are tests of sperm DNA damage clinically useful? Pros and Cons
    • A. Zini, and M. Sigman Are tests of sperm DNA damage clinically useful? Pros and Cons Journal of Andrology 30 2009 219 229
    • (2009) Journal of Andrology , vol.30 , pp. 219-229
    • Zini, A.1    Sigman, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.