Does the presence of nuclear vacuoles in human sperm selected for ICSI affect pregnancy outcome?

Human Reproduction

Volumn 21, Issue 7, 2006, Pages 1787-1790

  Berkovitz, Arie ^a   Eltes, Fina ^b   Ellenbogen, Adrian ^c   Peer, Sigal ^b   Feldberg, Dov ^d   Bartoov, Benjamin ^b  

^a MEIR MEDICAL CENTER   (Israel)

^b BAR ILAN UNIVERSITY   (Israel)

^c HILLEL YAFFE MEDICAL CENTER   (Israel)

^d Institute of Medical Genetics   (Israel)

Author keywords

IVF pregnancy outcome; IVF ICSI; Vacuolated spermatozoa

Indexed keywords

ABORTION; ADULT; ARTICLE; CELL NUCLEUS; CELL SHAPE; CELL VACUOLE; CONTROLLED STUDY; EMBRYO; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HUMAN; HUMAN CELL; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; MALE; MICROINJECTION; MORPHOLOGY; PREGNANCY OUTCOME; PREGNANCY RATE; SPERMATOZOON;

EID: 33745857346     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/del049     Document Type: Article

References (22)

1. Barth AD (1984) The effect of nuclear vacuoles in bovine spermatozoa on fertility in superovulated heifers. Proc Can. West Soc. Reprod. Biol. Saskatoon. 4-5.
2. Barth AD and Oko RJ (1988) Defects of the sperm head. In Barth AD, Oko RJ (eds) Abnormal Morphology of Bovine Spermatozoa. IS Iowa State University Press, Ames, pp. 130-192.
3. Bartoov B, Eltes F, Pansky M, Langzam J, Reichart M and Soffer Y (1994) Improved diagnosis of male fertility potential via a combination of quantitative ultramorphology and routine semen analysis. Hum Reprod 9, 2069-2075.
4. Bartoov B, Berkovitz A and Eltes F (2001) Selection of spermatozoa with normal nuclei to improve the pregnancy rate with intracytoplasmic sperm injection. [Letter] N Engl J Med 345,1067-1068.
5. Bartoov B, Berkovitz A, Eltes F, Kogosowski A, Menezo Y and Barak Y (2002) Relationship between human sperm subtle morphological characteristics and IVF-ICSI outcome. J Androl 23,1-8.
6. Bartoov B, Berkovitz A, Eltes F, Kogosovsky A, Yagoda A, Lederman H et al. (2003) Pregnancy rates are higher with intracytoplasmic morphologically selected sperm injection than with conventional intracytoplasmic injection. Fertil Steril 80,1413-1419.
7. Berkovitz A, Eltes F, Yaari S, Katz N, Barr I, Fishman A and Bartoov B (2005) The morphological normalcy of the sperm nucleus and pregnancy rate of intracytoplasmic injection with morphologically selected sperm. Hum Reprod 20,185-190.
8. Calogero AE (2003) Absolute polymorphic teratozoospermia in patients with oligo-asthenozoospermia is associated with an elevated sperm aneuploidy rate. J Androl 24,598-603.
9. Calogero AE, Burrello N, De Palma A, Barone N, D'Agata R and Vicari E (2003) Sperm aneuploidy in infertile men. Reprod Biomed Online 6 (3),310-317.
10. Carrell DT, Emery BR, Wilcox AL, Campbell B, Erickson L, Hatasaka HH, Jones KP and Peterson CM (2004) Sperm chromosome aneuploidy as related to male factor infertility and some ultrastructure defects. Arch Androl 50,181-185.
11. Carrell DT, Wilcox AL, Lowy L, Peterson CM, Jones KP, Erickson L, Campbell B, Branch DW and Hatasaka HH (2003) Elevated sperm chromosome aneuploidy and apoptosis in patients with unexplained recurrent pregnancy loss. Obstet Gynecol 101,1229-1235.
12. De Vos A, Van De Velde H, Joris H, Verheyen G, Devroey P and Van Steirteghem A (2003) Influence of individual sperm morphology on fertilisation, embryo morphology, and pregnancy outcome of intracytoplasmic sperm injection. Fertil Steril 79,42-48.
13. Junco AM, Cohen-Bacrie P and Hazout A (2004a) Improvement of fertilisation and pregnancy rate after intracytoplasmic fine morphology selected sperm injection. Fertil Steril 82 (Suppl 2),s173.
14. Junco AM, Dumont-Hassan M, Convert F, Cohen-Bacrie P, Le-Meur A and Hazout A (2004b) High magnification and intracytoplasmic injection. Abstracts of the 20th Annual Meeting of the ESHRE, Berlin, Germany. Hum Reprod 19 (Suppl. 1),i54-i55.
15. Kahraman S, Akarsu C, Cengiz G, Dirican K, Sozen E, Can B, Guven C and Vanderzwalmen P (1999) Fertility of ejaculated and testicular megalohead spermatozoa with intracytoplasmic sperm injection. Hum Reprod 14,726-730.
16. Miller JE and Smith TT (2001) The effect of intracytoplasmic sperm injection and semen parameters on blastocyst development in vitro. Hum Reprod 16,918-924.
17. Mundy AJ, Ryder TA and Edmonds DK (1994) A quantitative study of sperm head ultrastructure in subfertile males with excess sperm precursors. Fertil Steril 61,751-754.
18. Osawa Y, Sueoka K, Iwata S, Shinohara M, Kobayashi N, Kuji N and Yoshimura Y (1999) Assessment of the dominant abnormal form is useful for predicting the outcome of intracytoplasmic sperm injection in the case of severe teratozoospermia. J Assist Reprod Genet 16,436-442.
19. Sailer BL, Jost LK and Evenson DP (1996) Bull sperm head morphometry related to abnormal chromatin structure and fertility. Cytometry 24, 167-173.
20. Thundathil J, Palasz AT, Barth AD and Mapletoft RJ (1998) Fertilisation characteristics and in vitro embryo production with bovine sperm containing multiple nuclear vacuoles. Mol Reprod Dev 50,328-333.
21. Vicari E, de Palma A, Burrello N, Longo G, Grazioso C, Barone N, Zahi M, D'Agata Check JH, Graziano V, Cohen R et al. (2005) Effect of an abnormal sperm chromatin structural assay (SCSA) on pregnancy outcome following (IVF) with ICSI in previous IVF failures. Arch Androl 51,121-124.
22. Virro MR, Larson-Cook KL and Evenson DP (2004) Sperm chromatin structure assay (SCSA) parameters are related to fertilisation, blastocyst development, and ongoing pregnancy in in vitro fertilisation and intracytoplasmic sperm injection cycles. Fertil Steril 81,1289-1295.