Differential vulnerability of cortical and cerebellar neurons in primary culture to oxygen glucose deprivation followed by reoxygenation

Journal of Neuroscience Research

Volumn 63, Issue 1, 2001, Pages 20-26

  Scorziello, Antonella ^a   Pellegrini, Concetta ^a   Forte, Lavinia ^a   Tortiglione, Anna ^a   Gioielli, Anna ^a   Iossa, Silvana ^a   Amoroso, Salvatore ^a   Tufano, Rosalba ^a   Renzo, Gianfranco Di ^b   Annunziato, Lucio ^a,c  

^a Special Section of Surgical Digestive Endoscopy   (Italy)

^b UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^c NONE   (Italy)

Author keywords

Cellular; Death; Free radicals; Mitochondrial oxidative capacity; Neurons; OGD reoxygenation

Indexed keywords

ADENOSINE TRIPHOSPHATE; CARBON DIOXIDE; FLUORESCEIN DIACETATE; FREE RADICAL; GLUCOSE; LACTATE DEHYDROGENASE; MALONALDEHYDE; NITROGEN; OXYGEN; PROPIDIUM IODIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL CELL; ARTICLE; BRAIN CELL; BRAIN NERVE CELL; CELL HYPOXIA; CELL SURVIVAL; CONTROLLED STUDY; ENZYME RELEASE; GRANULE CELL; LIPID PEROXIDATION; MITOCHONDRION; NERVE CELL CULTURE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RAT; REOXYGENATION; STARVATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANOXIA; BRAIN ISCHEMIA; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; CEREBRAL CORTEX; GLUCOSE; MALONDIALDEHYDE; MITOCHONDRIA; NERVE DEGENERATION; RATS; REPERFUSION INJURY;

EID: 0035149790     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4547(20010101)63:1<20::AID-JNR3>3.0.CO;2-N     Document Type: Article

References (35)

1. 2+ exchanger protects C6 glioma cells during chemical hypoxia
2. 2+ increase
3. Pathophysiology of the ischemic penumbra- revision of a concept
4. Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose-deprivation or excitatory amino acids
5. The role of glutamate neuroxicity in hypoxic/ischemic neuronal death
6. Determination of aldehydic lipid peroxidation products: Monoaldehyde and 4-hydroxynonenal
7. Free radicals as mediators of neuronal injury
8. Lipid peroxides in the free radical pathophysiology of brain diseases
9. Ischemia and hypoxia
10. Mitochondria in neurodegeneration: Acute ischemia and chronic neurodegenerative diseases
11. The role of depolarization in the survival and differentiation of cerebellar granule cells in culture
12. Intracellular free calcium increases in cultured cortical neurons deprived of oxygen and glucose
13. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell killing
14. Reactive oxygen species and programmed cell death
15. Reperfusion injury after focal cerebral ischemia. The role of inflammation and the therapeutic horizon
16. Role of superoxide dismutase in ischemic brain injury: A study using SOD-1 transgenic mice
17. Mitochondrial respiration during recirculation after prolonged ischemia in cat brain
18. Ischemic cell death in brain neurons
19. Protein measurement with the folin phenol reagent
20. The enzymatic measurement of adenine nucleotides and P-creatine in picomole amounts
21. Sodium channel blockers reduce oxygen-glucose deprivation-induced cortical neuronal injury when combined with glutamate receptor antagonists
22. Role of neutrophils in radical production during ischemia and reperfusion of the rat brain: Effect of neutrophil depletion on extracellular ascorbyl radical formation
23. The early events of oxygen and glucose deprivation: Setting the scene for neuronal death
24. Mitochondria in neurodegeneration: Bioenergetic function in cell life and death
25. Increased formation of reactive oxygen species after permanent and reversible middle cerebral artery occlusion in the rat
26. Ischemia/reperfusion-induced injury of forebrain mitochondria and protection by ascorbate
27. Ischemic injury to rat forebrain mitochondria and cellular calcium homeostasis
28. 2+ homeostasis and rescues cortical neurons from apoptotic death
29. β 25-35 alters calcium homeostasis and induces neurotoxicity in cerebellar granule cells
30. Pathophysiology and treatment of focal cerebral ischemia I. Pathophysiology
31. Is the cell death pathway triggered by the mitochondrion or the endoplasmic reticulum?
32. Mechanisms of secondary brain damage in global and focal ischemia: A speculative synthesis
33. Biochemical changes associated with selective neuronal death after short-term cerebral ischemia
34. Ischemia-induced changes in cerebral mitochondrial acids, phospholipids and respiration in the rat
35. 2+ release from mitochondria