Sulfamate proton solvent exchange in heparin oligosaccharides: Evidence for a persistent hydrogen bond in the antithrombin-binding pentasaccharide Arixtra

Glycobiology

Volumn 22, Issue 9, 2012, Pages 1173-1182

  Langeslay, Derek J ^a   Young, Robert P ^a   Beni, Szabolcs ^a,b   Beecher, Consuelo N ^a   Mueller, Leonard J ^a   Larive, Cynthia K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

conformation; heparin; N sulfoglucosamine; NMR

Indexed keywords

ANTITHROMBIN III; DISACCHARIDE; FONDAPARINUX; MONOSACCHARIDE; PENTASACCHARIDE; TETRASACCHARIDE;

ARTICLE; DRUG BINDING; DRUG STRUCTURE; DRUG SULFATION; HYDROGEN BOND; PH; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TEMPERATURE;

ANTICOAGULANTS; ANTITHROMBIN III; BINDING SITES; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; HEPARIN; HEPARITIN SULFATE; HUMANS; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGOSACCHARIDES; POLYSACCHARIDES; PROTEIN BINDING; PROTONS; SOLUTIONS; SULFONIC ACIDS; TEMPERATURE;

TETRA;

EID: 84864419337     PISSN: 09596658     EISSN: 14602423     Source Type: Journal    
DOI: 10.1093/glycob/cws085     Document Type: Article

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