Cdk5 levels oscillate during the neuronal cell cycle: Cdh1 Ubiquitination triggers proteosome-dependent degradation during S-phase

Journal of Biological Chemistry

Volumn 287, Issue 31, 2012, Pages 25985-25994

  Zhang, Jie ^a,b   Li, Huifang ^b   Zhou, Tingwen ^b   Zhou, Jiechao ^b   Herrup, Karl ^b  

^a XIAMEN UNIVERSITY   (China)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; CELL CYCLE; CYCLIN-DEPENDENT KINASE; E3 LIGASE; NEURONAL CELL; PROTEASOMES; PROTECTIVE FUNCTION; RE-ACTIVATION; S-PHASE; UBIQUITINATION;

CELL DEATH; DEGRADATION; NEURODEGENERATIVE DISEASES;

NEURONS;

APC PROTEIN; CYCLIN DEPENDENT KINASE 5; PROTEASOME; PROTEIN P35; UBIQUITIN PROTEIN LIGASE E3; UVOMORULIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BINDING SITE; BRAIN DEVELOPMENT; BRAIN NERVE CELL; CELL CYCLE S PHASE; CELL LOSS; CONTROLLED STUDY; EMBRYO; ENZYME DEGRADATION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OSCILLATORY POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; UBIQUITINATION;

ANIMALS; CELL CYCLE PROTEINS; CELL NUCLEUS; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 5; ENZYME STABILITY; MICE; MICE, INBRED C57BL; NEURONS; PEPTIDE FRAGMENTS; PHOSPHOTRANSFERASES; PRIMARY CELL CULTURE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; PROTEOLYSIS; S PHASE CELL CYCLE CHECKPOINTS; UBIQUITINATION;

EID: 84864392483     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.343152     Document Type: Article

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