Impairments to the GH-IGF-I axis in hSOD1 G93A mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis

Endocrinology

Volumn 153, Issue 8, 2012, Pages 3735-3746

  Steyn, Frederik J ^a,b   Ngo, Shyuan T ^a   Lee, J D ^a   Leong, J W ^a   Buckley, A J ^a   Veldhuis, J D ^c   McCombe, P A ^b,d   Chen, Chen ^a   Bellingham, M C ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c MAYO CLINIC   (United States)

^d ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; GROWTH FACTOR RECEPTOR; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; GROWTH HORMONE RELEASING FACTOR RECEPTOR; INSULIN LIKE GROWTH FACTOR 1 RECEPTOR ALPHA; MESSENGER RNA; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; SOMATOSTATIN; SOMATOSTATIN RECEPTOR 2; SOMATOSTATIN RECEPTOR 5; UNCLASSIFIED DRUG;

ADENOHYPOPHYSIS; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; GASTROCNEMIUS MUSCLE; GENE EXPRESSION; GROWTH HORMONE DEFICIENCY; GROWTH HORMONE RELEASE; HYPOTHALAMUS; LUMBAR SPINAL CORD; MALE; MOTONEURON; MOUSE; MUSCLE DENERVATION; NONHUMAN; NUTRITIONAL DEFICIENCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BLOTTING, WESTERN; FLUORESCENT ANTIBODY TECHNIQUE; GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, TRANSGENIC; MUSCLE, SKELETAL; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, IGF TYPE 1; RECEPTORS, SOMATOTROPIN; SOMATOMEDINS; SUPEROXIDE DISMUTASE;

EID: 84864389648     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-2171     Document Type: Article

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