Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3

Marine Drugs

Volumn 10, Issue 7, 2012, Pages 1511-1527

  Jensen, Jonas E ^a   Mobli, Mehdi ^a   Brust, Andreas ^a   Alewood, Paul F ^a   King, Glenn F ^a   Rash, Lachlan D ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

APETx2; ASIC3; Cyclisation; Peptide; Sea anemone; Stability; Truncation

Indexed keywords

ACID SENSING ION CHANNEL; ACID SENSING ION CHANNEL 3; ANALGESIC AGENT; APETX2 PEPTIDE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYCLIZATION; DRUG DESIGN; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYMATIC DEGRADATION; PROTEIN STABILITY;

ACTINIARIA; ANTHOPLEURA ELEGANTISSIMA;

EID: 84864388688     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md10071511     Document Type: Article

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