Sirt1, p53, and p38MAPK are crucial regulators of detrimental phenotypes of embryonic stem cells with Max expression ablation

Stem Cells

Volumn 30, Issue 8, 2012, Pages 1634-1644

  Hishida, Tomoaki ^a   Nozaki, Yuriko ^a   Nakachi, Yutaka ^a   Mizuno, Yosuke ^a   Iseki, Hiroyoshi ^a   Katano, Miyuki ^a   Kamon, Masayoshi ^a   Hirasaki, Masataka ^a   Nishimoto, Masazumi ^b   Okazaki, Yasushi ^a   Okuda, Akihiko ^a  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Apoptosis; c Myc; Embryonic stem cells; p53; Pluripotency

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; COMPLEMENTARY RNA; DOXYCYCLINE; LENTIVIRUS VECTOR; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MYC PROTEIN; N (2,3 DIHYDROXYPROPOXY) 3,4 DIFLUORO 2 (2 FLUORO 4 IODOANILINO)BENZAMIDE; NICOTINAMIDE; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN P53; PUROMYCIN; SHORT HAIRPIN RNA; SIRTUIN 1;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL CYCLE; CELL DEATH; CELL RENEWAL; CONTROLLED STUDY; EMBRYONIC STEM CELL; ENZYME ACTIVITY; ENZYME ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; NICK END LABELING; PHENOTYPE; PLURIPOTENT STEM CELL; WESTERN BLOTTING;

ANTIOXIDANTS; BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL DEATH; CELL DIFFERENTIATION; DOXYCYCLINE; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOTYPE; PLURIPOTENT STEM CELLS; PROTEIN KINASE INHIBITORS; SIRTUIN 1; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84864370845     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1147     Document Type: Article

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