Activity-guided discovery of (S)-malic acid 1′- O -β-gentiobioside as an angiotensin I-converting enzyme inhibitor in lettuce (lactuca sativa)

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 29, 2012, Pages 7211-7217

  Lagemann, Annika ^a   Dunkel, Andreas ^a   Hofmann, Thomas ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

(S) malic acid 1 O gentiobioside; ACE; angiotensin converting enzyme; blood pressure; hypertension

Indexed keywords

ACE; ACE INHIBITION; ACE INHIBITORS; ACE-INHIBITORY ACTIVITY; ACTIVE COMPOUNDS; ANGIOTENSIN I; ANGIOTENSIN I CONVERTING ENZYME INHIBITOR; ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME; FUNCTIONAL FOODS; GLYCOSIDASES; HYPERTENSION; IN-VITRO ASSAYS; MALIC ACIDS; PHYTOCHEMICALS;

BLOOD PRESSURE; EXPERIMENTS; HYDROCHLORIC ACID; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SUGARS;

ENZYMES;

(S) MALIC ACID 1' O BETA GENTIOBIOSIDE; (S)-MALIC ACID 1'-O-BETA-GENTIOBIOSIDE; ANTIHYPERTENSIVE AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLYCOSIDE; MALIC ACID DERIVATIVE; PLANT EXTRACT;

ARTICLE; CHEMISTRY; DRUG STABILITY; FUNCTIONAL FOOD; LETTUCE; SALIVA; VEGETABLE;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANTIHYPERTENSIVE AGENTS; DRUG STABILITY; FUNCTIONAL FOOD; GLYCOSIDES; LETTUCE; MALATES; PLANT EXTRACTS; SALIVA; VEGETABLES;

LACTUCA; LACTUCA SATIVA;

EID: 84864350421     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf3022157     Document Type: Article

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