메뉴 건너뛰기




Volumn 4, Issue 8, 2012, Pages 621-628

Crystal structures of λ-[Ru(phen) 2 dppz] 2+ with oligonucleotides containing TA/TA and AT/AT steps show two intercalation modes

Author keywords

[No Author keywords available]

Indexed keywords

COORDINATION COMPOUND; INTERCALATING AGENT; OLIGONUCLEOTIDE; ORGANOMETALLIC COMPOUND; RU(PHEN)(2)DIPYRIDO(3,2-A-2',3'-C)PHENAZINE; RUTHENIUM;

EID: 84864329345     PISSN: 17554330     EISSN: 17554349     Source Type: Journal    
DOI: 10.1038/nchem.1397     Document Type: Article
Times cited : (180)

References (43)
  • 1
    • 85048645035 scopus 로고
    • Structural considerations in the interaction of deoxyribonucleic acid and acridines
    • Lerman, L. S. Structural considerations in the interaction of deoxyribonucleic acid and acridines. J. Mol. Biol. 3, 18-30 (1961
    • (1961) J. Mol. Biol. , vol.3 , pp. 18-30
    • Lerman, L.S.1
  • 2
    • 0018866267 scopus 로고
    • The structure of a drug-deoxydinucleoside phosphate complex; generalized conformational behaviour of intercalation complexes with rna and dna fragments
    • Shieh, H.-S., Berman, H. M., Dabrow, M. & Neidle, S. The structure of a drug-deoxydinucleoside phosphate complex; generalized conformational behaviour of intercalation complexes with RNA and DNA fragments. Nucleic Acids Res. 8, 85-98 (1980
    • (1980) Nucleic Acids Res. , vol.8 , pp. 85-98
    • Shieh, H.-S.1    Berman, H.M.2    Dabrow, M.3    Neidle, S.4
  • 3
    • 0018659302 scopus 로고
    • The molecular basis for the action of some dna-binding drugs
    • Neidle, S. The molecular basis for the action of some DNA-binding drugs. Prog. Med. Chem. 16, 151-221 (1979
    • (1979) Prog. Med. Chem. , vol.16 , pp. 151-221
    • Neidle, S.1
  • 4
    • 0033602134 scopus 로고    scopus 로고
    • 2 at 1.3-A resolution [2]
    • DOI 10.1021/jm980479u
    • Todd, A. K. et al. Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3 Å resolution. J. Med. Chem. 42, 536-540 (1999 (Pubitemid 29110769)
    • (1999) Journal of Medicinal Chemistry , vol.42 , Issue.4 , pp. 536-540
    • Todd, A.K.1    Adams, A.2    Thorpe, J.H.3    Denny, W.A.4    Wakelin, L.P.G.5    Cardin, C.J.6
  • 5
    • 33845889214 scopus 로고    scopus 로고
    • 2 molecules by a bis(9-aminoacridine-4- carboxamide) derivative
    • DOI 10.1093/nar/gkl930
    • Hopcroft, N. H., Brogden, A. L., Searcey, M. & Cardin, C. J. X-ray crystallographic study of DNA duplex cross-linking: simultaneous binding to two d(CGTACG)2 molecules by a bis(9-aminoacridine-4-carboxamide) derivative. Nucleic Acids Res. 34, 6663-6672 (2006 (Pubitemid 46017958)
    • (2006) Nucleic Acids Research , vol.34 , Issue.22 , pp. 6663-6672
    • Hopcroft, N.H.1    Brogden, A.L.2    Searcey, M.3    Cardin, C.J.4
  • 6
    • 34250716392 scopus 로고    scopus 로고
    • Ligand bridging of the dna holliday junction: Molecular recognition of a stacked-x four-way junction by a small molecule
    • Brogden, A. L., Hopcroft, N. H., Searcey, M. & Cardin, C. J. Ligand bridging of the DNA Holliday junction: molecular recognition of a stacked-X four-way junction by a small molecule. Angew. Chem. Int. Ed. 119, 3924-3928 (2007
    • (2007) Angew. Chem. Int. Ed. , Issue.119 , pp. 3924-3928
    • Brogden, A.L.1    Hopcroft, N.H.2    Searcey, M.3    Cardin, C.4
  • 8
    • 18744395179 scopus 로고    scopus 로고
    • Crystal structure of actinomycin D bound to the CTG triplet repeat sequences linked to neurological diseases
    • Hou, M.-H., Robinson, H., Gao, Y.-G. & Wang, A. H.-J. Crystal structure of actinomycin D bound to the CTG triplet repeat sequence linked to neurological diseases. Nucleic Acids Res. 30, 4910-4917 (2002 (Pubitemid 35414651)
    • (2002) Nucleic Acids Research , vol.30 , Issue.22 , pp. 4910-4917
    • Hou, M.-H.1    Robinson, H.2    Gao, Y.-G.3    Wang, A.H.-J.4
  • 9
    • 35448933939 scopus 로고    scopus 로고
    • Biophysical tools for biologists: Vol. 1 in vitro techniques
    • Garbett, N. C. & Chaires, J. B. Biophysical tools for biologists: vol. 1 in vitro techniques. Methods Cell Biol. 84, 3-23 (2008
    • (2008) Methods Cell Biol. , Issue.84 , pp. 3-23
    • Garbett, N.C.1    Chaires, J.B.2
  • 10
    • 34447137400 scopus 로고    scopus 로고
    • DNA intercalators in cancer therapy: Organic and inorganic drugs and their spectroscopic tools of analysis
    • DOI 10.2174/138955707780859413
    • Wheate, N. J., Brodie, C. R., Collins, J. G., Kemp, S. & Aldrich-Wright, J. R. DNA intercalators in cancer therapy: organic and inorganic drugs and their spectroscopic tools of analysis. Mini Rev. Med. Chem. 7, 627-648 (2007 (Pubitemid 47099183)
    • (2007) Mini-Reviews in Medicinal Chemistry , vol.7 , Issue.6 , pp. 627-648
    • Wheate, N.J.1    Brodie, C.R.2    Collins, J.G.3    Kemp, S.4    Aldrich-Wright, J.R.5
  • 11
    • 8544273289 scopus 로고    scopus 로고
    • Novel DNA bis-intercalation by MLN944, a potent clinical bisphenazine anticancer drug
    • DOI 10.1074/jbc.M404053200
    • Dai, J., Punchihewa, C., Mistry, P., Ooi, A. T. & Yang, D. Novel DNA bis-intercalation by MLN944, a potent clinical bisphenazine anticancer drug. J. Biol. Chem. 279, 46096-46103 (2004 (Pubitemid 39491603)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.44 , pp. 46096-46103
    • Dai, J.1    Punchihewa, C.2    Mistry, P.3    Ooi, A.T.4    Yang, D.5
  • 12
    • 35948933867 scopus 로고    scopus 로고
    • Metallo-intercalators and metallo-insertors
    • Zeglis, B. M., Pierre, V. C. & Barton, J. K. Metallo-intercalators and metallo-insertors. Chem. Commun. 44, 4549-4696 (2007
    • (2007) Chem. Commun. , vol.44 , pp. 4549-4696
    • Zeglis, B.M.1    Pierre, V.2    Barton, J.3
  • 13
    • 79956196513 scopus 로고    scopus 로고
    • Metal complexes as dna intercalators
    • Liu, H.-K. & Sadler, P. J. Metal complexes as DNA intercalators. Acc. Chem. Res. 44, 349-359 (2011
    • (2011) Acc. Chem. Res. , vol.44 , pp. 349-359
    • Liu, H.-K.1    Sadler, P.2
  • 14
    • 58149265215 scopus 로고    scopus 로고
    • Dna-binding drugs caught in action: The latest 3d pictures of drug-dna complexes
    • Boer, D. R., Canals, A. & Coll, M. DNA-binding drugs caught in action: the latest 3D pictures of drug-DNA complexes. Dalton Trans. 3, 399-414 (2009
    • (2009) Dalton Trans. , Issue.3 , pp. 399-414
    • Boer, D.R.1    Canals, A.2    Coll, M.3
  • 15
    • 0001594263 scopus 로고
    • Ru(bipy)2(dypyridophenazine) 2+: A complex with a long range directed charge transfer excited state
    • Chambron, J. C., Sauvage, J. P., Amouyal, E. & Koffi, P. Ru(bipy)2(dypyridophenazine)2+: a complex with a long range directed charge transfer excited state. Nouv. J. Chim. 9, 527-529 (1985
    • (1985) Nouv. J. Chim. , vol.9 , pp. 527-529
    • Chambron, J.C.1    Sauvage, J.P.2    Amouyal, E.3    Koffi, P.4
  • 16
    • 80052735331 scopus 로고    scopus 로고
    • Environmental effects on the photophysics of transition metal complexes with dipyrido[2,3-1:3', 2'-c]phenazine (dppz) and related ligands
    • McKinley, A. W., Lincoln, P. & Tuite, E. M. Environmental effects on the photophysics of transition metal complexes with dipyrido[2,3-1:3', 2'-c]phenazine (dppz) and related ligands. Coord. Chem. Rev. 255, 2676-2692 (2011
    • (2011) Coord. Chem. Rev. , vol.255 , pp. 2676-2692
    • McKinley, A.W.1    Lincoln, P.2    Tuite, E.M.3
  • 18
    • 12044251476 scopus 로고
    • Dna binding of d- and l-ru(phen)2dppz]2+
    • Hiort, C., Lincoln, P. & Norden, B. DNA binding of D- and L-Ru(phen)2dppz]2+. J. Am. Chem. Soc. 115, 3448-3454 (1993
    • (1993) J. Am. Chem. Soc. , vol.115 , pp. 3448-3454
    • Hiort, C.1    Lincoln, P.2    Norden, B.3
  • 19
    • 80052719287 scopus 로고    scopus 로고
    • Transient spectroscopy of dipyridophenazine metal complexes which undergo photo-induced electron transfer with dna
    • Smith, J. A., George, M. W. & Kelly, J. M. Transient spectroscopy of dipyridophenazine metal complexes which undergo photo-induced electron transfer with DNA. Coord. Chem. Rev. 255, 2666-2675 (2011
    • (2011) Coord. Chem. Rev. , vol.255 , pp. 2666-2675
    • Smith, J.A.1    George, M.W.2    Kelly, J.3
  • 20
    • 38049107206 scopus 로고    scopus 로고
    • Photooxidation of guanine by a ruthenium dipyridophenazine complex intercalated in a double-stranded polynucleotide monitored directly by picosecond visible and infrared transient absorption spectroscopy
    • Elias, B. et al. Photooxidation of guanine by a ruthenium dipyridophenazine complex intercalated in a double-stranded polynucleotide monitored directly by picosecond visible and infrared transient absorption spectroscopy. Chem. Eur J. 14, 369-375 (2007
    • (2007) Chem. Eur J. , vol.14 , pp. 369-375
    • Elias, B.1
  • 21
    • 79952104649 scopus 로고    scopus 로고
    • Metal complexes for dna-mediated charge transport
    • Barton, J. K., Olmon, E. D. & Sontz, P. A. Metal complexes for DNA-mediated charge transport. Coord. Chem. Rev. 255, 619-634 (2011
    • (2011) Coord. Chem. Rev. , vol.255 , pp. 619-634
    • Barton, J.K.1    Olmon, E.D.2    Sontz, P.3
  • 22
    • 0026722927 scopus 로고
    • Novel dipyridophenazine complexes of ruthenium(ii): Exploring luminescent reporters of dna
    • Hartshorn, R. M. & Barton, J. K. Novel dipyridophenazine complexes of ruthenium(II): exploring luminescent reporters of DNA. J. Am. Chem. Soc. 114, 5919-5925 (1992
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 5919-5925
    • Hartshorn, R.M.1    Barton, J.2
  • 23
    • 0029993524 scopus 로고    scopus 로고
    • Diastereomeric dna-binding geometries of intercalating ruthenium (ii) trischelates probed by linear dichroism: [ru(phen)2dppz] 2+ and [ru(phen)2bdppz]2+
    • Lincoln, P., Broo, A. & Nordén, B. Diastereomeric DNA-binding geometries of intercalating ruthenium (II) trischelates probed by linear dichroism: [Ru(phen)2dppz]2+ and [Ru(phen)2bdppz]2+. J. Am. Chem. Soc. 118, 2644-2653 (1996
    • (1996) J. Am. Chem. Soc. , Issue.118 , pp. 2644-2653
    • Lincoln, P.1    Broo, A.2    Nordén, B.3
  • 24
    • 0028989079 scopus 로고
    • Interaction of d- and l-ru(phen)2dppz]2+ with dna: A calorimetric and equilibrium binding study
    • Haq, I. et al. Interaction of D- and L-Ru(phen)2dppz]2+ with DNA: a calorimetric and equilibrium binding study. J. Am. Chem. Soc. 117, 4788-4796 (1995
    • (1995) J. Am. Chem. Soc. , vol.117 , pp. 4788-4796
    • Haq, I.1
  • 25
    • 80055070319 scopus 로고    scopus 로고
    • Structure determination of an intercalation ruthenium dipyridophenazine complex which kinks dna by semiintercalation of a tetraazaphenanthrene ligand
    • Hall, J. P. et al. Structure determination of an intercalation ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand. Proc. Natl Acad. Sci. USA 108, 17610-17614 (2011
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 17610-17614
    • Hall, J.P.1
  • 26
    • 0031055332 scopus 로고    scopus 로고
    • 2+ intercalate DNA from the minor groove
    • DOI 10.1021/ja961857s, PII S0002786396018574
    • Tuite, E., Lincoln, P. & Nordén, B. Photophysical evidence that D- and L-[Ru(phen)2(dppz)]2+ intercalate DNA from the minor groove. J. Am. Chem. Soc. 119, 239-240 (1997 (Pubitemid 27064508)
    • (1997) Journal of the American Chemical Society , vol.119 , Issue.1 , pp. 239-240
    • Tuite, E.1    Lincoln, P.2    Norden, B.3
  • 32
    • 9144234841 scopus 로고    scopus 로고
    • [Ru(bpy)2dppz]2+ lightswitch mechanism in protic solvents as studies through temperature-dependent lifetime measurements
    • Brennaman, M. K., Meyer, T. J. & Papanikolas, J. M. [Ru(bpy)2dppz]2+ lightswitch mechanism in protic solvents as studies through temperature- dependent lifetime measurements. J. Phys. Chem. A 108, 9938-9944 (2004
    • (2004) J. Phys. Chem. A , vol.108 , pp. 9938-9944
    • Brennaman, M.K.1    Meyer, T.J.2    Papanikolas, J.3
  • 33
    • 0037456311 scopus 로고    scopus 로고
    • Picosescond and steady state emission of [ru(phen)2dppz]2+ in glycerol: Anomalous temperature dependence
    • Önfeld, T., Olofsson, J., Lincoln, P. & Nordén, B. Picosescond and steady state emission of [Ru(phen)2dppz]2+ in glycerol: anomalous temperature dependence. J. Phys. Chem A 107, 1000-1009 (2003
    • (2003) J. Phys. Chem A , vol.107 , pp. 1000-1009
    • Önfeld, T.1    Olofsson, J.2    Lincoln, P.3    Nordén, B.4
  • 35
    • 0032577074 scopus 로고    scopus 로고
    • A generalized McGhee-von Hippel method for the cooperative binding of different competing ligands to an infinite one-dimensional lattice
    • PII S0009261498003327
    • Lincoln, P. A generalised McGhee-von Hippel method for the cooperative binding of different competing ligands to an infinite one-dimensional lattice. Chem. Phys. Lett. 288, 647-656 (1998 (Pubitemid 128180996)
    • (1998) Chemical Physics Letters , vol.288 , Issue.5-6 , pp. 647-656
    • Lincoln, P.1
  • 36
    • 75649151032 scopus 로고    scopus 로고
    • Xia2: An expert system for macromolecular crystallography data reduction
    • Winter, G. Xia2: an expert system for macromolecular crystallography data reduction. J. Appl. Crystallogr. 43, 186-190 (2010
    • (2010) J. Appl. Crystallogr. , vol.43 , pp. 186-190
    • Winter, G.1
  • 37
    • 0027879008 scopus 로고
    • Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants
    • Kabsch, W. Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants. J. Appl. Crystallogr. 26, 795-800 (1993
    • (1993) J. Appl. Crystallogr. , vol.26 , pp. 795-800
    • Kabsch, W.1
  • 38
    • 33644875355 scopus 로고    scopus 로고
    • And assessment of data quality
    • Evans, P. Scaling and assessment of data quality. Acta Crystallogr. D 62, 72-82 (2006
    • (2006) Acta Crystallogr. D , vol.62 , pp. 72-82
    • Evans P. Scaling1
  • 41
    • 0028103275 scopus 로고
    • Collaborative computational project, number 4. The ccp4 suite: Programs for protein crystallography
    • Collaborative computational project, number 4. The CCP4 suite: programs for protein crystallography. Acta Crystallogr. D 50, 760-763 (1994
    • (1994) Acta Crystallogr. D , vol.50 , pp. 760-763
  • 42
    • 37549039510 scopus 로고    scopus 로고
    • A short history of shelx
    • Sheldrick, G. M. A short history of SHELX. Acta Crystallogr. D 64, 113-122 (2008
    • (2008) Acta Crystallogr. D , vol.64 , pp. 113-122
    • Sheldrick, G.M.1
  • 43
    • 0028927324 scopus 로고
    • Dna-nogalamycin interactions: The crystal structure of d(tgatca) complexed with nogalamycin
    • Smith, C. K., Davies, G. J., Dodson. E. J. & Moore, M. H. DNA-nogalamycin interactions: the crystal structure of d(TGATCA) complexed with nogalamycin. Biochemistry 34, 415-425 (1995).
    • (1995) Biochemistry , vol.34 , pp. 415-425
    • Smith, C.K.1    Davies, G.J.2    Dodson, E.J.3    Moore, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.