Pathological consequences of long-term mitochondrial oxidative stress in the mouse retinal pigment epithelium

Experimental Eye Research

Volumn 101, Issue , 2012, Pages 60-71

  Seo, Soo jung ^a   Krebs, Mark P ^a,b   Mao, Haoyu ^a   Jones, Kyle ^a   Conners, Mandy ^a   Lewin, Alfred S ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b JACKSON LABORATORY   (United States)

Author keywords

Age related macular degeneration; Mitochondria; Mouse model; Oxidative stress; Retinal pigment epithelium; Superoxide dismutase

Indexed keywords

HAMMERHEAD RIBOZYME; MANGANESE SUPEROXIDE DISMUTASE;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; ELECTRON MICROSCOPY; ELECTROPHYSIOLOGY; ELECTRORETINOGRAM; GENE SILENCING; MITOCHONDRION; MOUSE; NONHUMAN; OCULAR FIBROSIS; OPHTHALMOSCOPY; OXIDATIVE STRESS; PHOTORECEPTOR CELL; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA BIPOLAR GANGLION CELL; RETINA MACULA AGE RELATED DEGENERATION; SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY;

ANIMALS; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; FLUORESCEIN ANGIOGRAPHY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE SILENCING; GENETIC VECTORS; GEOGRAPHIC ATROPHY; HUMANS; MICE; MICE, INBRED C57BL; MITOCHONDRIA; OXIDATIVE STRESS; RETINAL PIGMENT EPITHELIUM; RNA, CATALYTIC; SUPEROXIDE DISMUTASE; TOMOGRAPHY, OPTICAL COHERENCE;

EID: 84864304982     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2012.05.013     Document Type: Article

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