Chlorogenic acid ameliorates brain damage and edema by inhibiting matrix metalloproteinase-2 and 9 in a rat model of focal cerebral ischemia

European Journal of Pharmacology

Volumn 689, Issue 1-3, 2012, Pages 89-95

  Lee, Kyungjin ^a   Lee, Jeong Sook ^a   Jang, Hyeung Jin ^a   Kim, Sung Moo ^a   Chang, Mun Seog ^a   Park, Si Hyung ^b   Kim, Kwan Su ^b   Bae, Jinhyun ^a   Park, Jae Woo ^a   Lee, Bumjun ^a   Choi, Ho Young ^a   Jeong, Chang Hyun ^a   Bu, Youngmin ^a  

^a Kyung Hee University   (South Korea)

^b Mokpo National University   (South Korea)

Author keywords

Blood brain barrier; Brain edema; Cerebral ischemia; Chlorogenic acid; Matrix metalloproteinase; Neuroprotection

Indexed keywords

CHLOROGENIC ACID; EVANS BLUE; GELATINASE A; GELATINASE B;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN DAMAGE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG TARGETING; ENZYME INHIBITION; EXPERIMENTAL RAT; LIPID PEROXIDATION; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION; SENSORIMOTOR NEUROPATHY;

ANIMALS; BRAIN EDEMA; BRAIN ISCHEMIA; CHLOROGENIC ACID; DISEASE MODELS, ANIMAL; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASE INHIBITORS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84864286019     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.05.028     Document Type: Article

References (47)

1. D. Amantea, R. Russo, M. Gliozzi, V. Fratto, L. Berliocchi, G. Bagetta, G. Bernardi, and M.T. Corasaniti Early upregulation of matrix metalloproteinases following reperfusion triggers neuroinflammatory mediators in brain ischemia in rat Int. Rev. Neurobiol. 82 2007 149 169
2. L. Belayev, O.F. Alonso, R. Busto, W. Zhao, and M.D. Ginsberg Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model Stroke 27 1996 1616 1622 (discussion 1623)
3. J.S. Bonita, M. Mandarano, D. Shuta, and J. Vinson Coffee and cardiovascular disease: in vitro, cellular, animal, and human studies Pharmacol. Res. 55 2007 187 198 (Pubitemid 46518151)
4. J. Bouayed, H. Rammal, A. Dicko, C. Younos, and R. Soulimani Chlorogenic acid, a polyphenol from Prunus domestica (Mirabelle), with coupled anxiolytic and antioxidant effects J. Neurol. Sci. 262 2007 77 84 (Pubitemid 47398894)
5. Y. Bu, S. Kwon, Y.T. Kim, M.Y. Kim, H. Choi, J.G. Kim, N. Jamarkattel-Pandit, S. Dore, S.H. Kim, and H. Kim Neuroprotective effect of HT008-1, a prescription of traditional Korean medicine, on transient focal cerebral ischemia model in rats Phytother. Res. 24 2010 1207 1212
6. P.S. Burrage, K.S. Mix, and C.E. Brinckerhoff Matrix metalloproteinases: role in arthritis Front. Biosci. 11 2006 529 543 (Pubitemid 43258162)
7. P.H. Chan Role of oxidants in ischemic brain damage Stroke 27 1996 1124 41129
8. W.C. Chang, C.H. Chen, M.F. Lee, T. Chang, and Y.M. Yu Chlorogenic acid attenuates adhesion molecules upregulation in IL-1beta-treated endothelial cells Eur. J. Nutr. 49 2009 267 275
9. A. Cherubini, C. Ruggiero, M.C. Polidori, and P. Mecocci Potential markers of oxidative stress in stroke Free Radic. Biol. Med. 39 2005 841 852
10. M.N. Clifford Chlorogenic acids and other cinnamates - nature, occurence and dietary burden J. Sci. Food Agric. 79 1999 362 372 (Pubitemid 29150578)
11. L.A. Cunningham, M. Wetzel, and G.A. Rosenberg Multiple roles for MMPs and TIMPs in cerebral ischemia Glia 50 2005 329 339 (Pubitemid 40780839)
12. E.I. Deryugina, and J.P. Quigley Matrix metalloproteinases and tumor metastasis Cancer Metastasis Rev. 25 2006 9 34 (Pubitemid 43723979)
13. M.D. dos Santos, M.C. Almeida, N.P. Lopes, and G.E. de Souza Evaluation of the anti-inflammatory, analgesic and antipyretic activities of the natural polyphenol chlorogenic acid Biol. Pharm. Bull. 29 2006 2236 2240 (Pubitemid 44690948)
14. S.C. Fagan, D.C. Hess, E.J. Hohnadel, D.M. Pollock, and A. Ergul Targets for vascular protection after acute ischemic stroke Stroke 35 2004 2220 2225 (Pubitemid 39129589)
15. G.A. Ford Clinical pharmacological issues in the development of acute stroke therapies Br. J. Pharmacol. 153 2008 S112 S119
16. T. Gerriets, M. Walberer, N. Ritschel, M. Tschernatsch, C. Mueller, G. Bachmann, M. Schoenburg, M. Kaps, and M. Nedelmann Edema formation in the hyperacute phase of ischemic stroke. Laboratory investigation J. Neurosurg. 111 2009 1036 1042
17. O. Gotoh, T. Asano, T. Koide, and K. Takakura Ischemic brain edema following occlusion of the middle cerebral artery in the rat. I: the time courses of the brain water, sodium and potassium contents and blood-brain barrier permeability to 125I-albumin Stroke 16 1985 101 109 (Pubitemid 15194765)
18. Z. Gu, J. Cui, S. Brown, R. Fridman, S. Mobashery, A.Y. Strongin, and S.A. Lipton A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia J. Neurosci. 25 2005 6401 6408 (Pubitemid 40962536)
19. J.V. Higdon, and B. Frei Coffee and health: a review of recent human research Crit. Rev. Food Sci. Nutr. 46 2006 101 123
20. M.J. Hobeika, R.W. Thompson, B.E. Muhs, P.C. Brooks, and P.J. Gagne Matrix metalloproteinases in peripheral vascular disease J. Vasc. Surg. 45 2007 849 857 (Pubitemid 46483940)
21. R. Jin, G. Yang, and G. Li Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: critical role of matrix metalloproteinases and tissue-type plasminogen activator Neurobiol. Dis. 38 2010 376 385
22. U.H. Jin, J.Y. Lee, S.K. Kang, J.K. Kim, W.H. Park, J.G. Kim, S.K. Moon, and C.H. Kim A phenolic compound, 5-caffeoylquinic acid (chlorogenic acid), is a new type and strong matrix metalloproteinase-9 inhibitor: isolation and identification from methanol extract of Euonymus alatus Life Sci. 77 2005 2760 2769
23. J. Kim, M.Y. Kim, K.H. Leem, S. Moon, N. Jamakattel-Pandit, H. Choi, H. Kim, and Y. Bu Key compound groups for the neuroprotective effect of roots of Polygonum cuspidatum on transient middle cerebral artery occlusion in Sprague-Dawley rats Nat. Prod. Res. 24 2011 1214 1226
24. D.E. Kleiner, and W.G. Stetler-Stevenson Quantitative zymography: detection of picogram quantities of gelatinases Anal. Biochem. 218 1994 325 329 (Pubitemid 24141631)
25. S.H. Kwon, H.K. Lee, J.A. Kim, S.I. Hong, H.C. Kim, T.H. Jo, Y.I. Park, C.K. Lee, Y.B. Kim, S.Y. Lee, and C.G. Jang Neuroprotective effects of chlorogenic acid on scopolamine-induced amnesia via anti-acetylcholinesterase and anti-oxidative activities in mice Eur. J. Pharmacol. 649 2010 210 217
26. P.A. Lapchak The phenylpropanoid micronutrient chlorogenic acid improves clinical rating scores in rabbits following multiple infarct ischemic strokes: synergism with tissue plasminogen activator Exp. Neurol. 205 2007 407 413 (Pubitemid 46766601)
27. S.C. Larsson, S. Mannisto, M.J. Virtanen, J. Kontto, D. Albanes, and J. Virtamo Coffee and tea consumption and risk of stroke subtypes in male smokers Stroke 39 2008 1681 1687
28. H. Lee, J.H. Bae, and S.R. Lee Protective effect of green tea polyphenol EGCG against neuronal damage and brain edema after unilateral cerebral ischemia in gerbils J. Neurosci. Res. 77 2004 892 900 (Pubitemid 39187072)
29. P. Lipton Ischemic cell death in brain neurons Physiol. Rev. 79 1999 1431 1568 (Pubitemid 29473320)
30. E.Z. Longa, P.R. Weinstein, S. Carlson, and R. Cummins Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 20 1989 84 91 (Pubitemid 19040218)
31. E. Lopez-Garcia, F. Rodriguez-Artalejo, K.M. Rexrode, G. Logroscino, F.B. Hu, and R.M. van Dam Coffee consumption and risk of stroke in women Circulation 119 2009 1116 1123
32. C.B. Matthew, I.V. Sils, and A.M. Bastille Tissue-specific extravasation of albumin-bound Evans blue in hypothermic and rewarmed rats Can. J. Physiol. Pharmacol. 80 2002 233 243 (Pubitemid 34264359)
33. A. Morancho, A. Rosell, L. Garcia-Bonilla, and J. Montaner Metalloproteinase and stroke infarct size: role for anti-inflammatory treatment? Ann. N. Y. Acad. Sci. 1207 2010 123 133
34. B. Ngameni, M. Touaibia, R. Patnam, A. Belkaid, P. Sonna, B.T. Ngadjui, B. Annabi, and R. Roy Inhibition of MMP-2 secretion from brain tumor cells suggests chemopreventive properties of a furanocoumarin glycoside and of chalcones isolated from the twigs of Dorstenia turbinata Phytochemistry 67 2006 2573 2579 (Pubitemid 44711963)
35. R. Ochiai, H. Jokura, A. Suzuki, I. Tokimitsu, M. Ohishi, N. Komai, H. Rakugi, and T. Ogihara Green coffee bean extract improves human vasoreactivity Hypertens. Res. 27 2004 731 737 (Pubitemid 40045512)
36. M.R. Olthof, P.C. Hollman, and M.B. Katan Chlorogenic acid and caffeic acid are absorbed in humans J. Nutr. 131 2001 66 71 (Pubitemid 32060624)
37. K. Puurunen, J. Jolkkonen, J. Sirvio, A. Haapalinna, and J. Sivenius An alpha(2)-adrenergic antagonist, atipamezole, facilitates behavioral recovery after focal cerebral ischemia in rats Neuropharmacology 40 2001 597 606 (Pubitemid 32209045)
38. M. Ramos-Fernandez, M.F. Bellolio, and L.G. Stead Matrix metalloproteinase-9 as a marker for acute ischemic stroke: a systematic review J. Stroke Cerebrovasc. Dis. 20 2010 47 54
39. M. Rodriguez-Yanez, M. Castellanos, M. Blanco, E. Mosquera, and J. Castillo Vascular protection in brain ischemia Cerebrovasc. Dis. 21 Suppl 2 2006 21 29
40. A. Rosell, and E.H. Lo Multiphasic roles for matrix metalloproteinases after stroke Curr. Opin. Pharmacol. 8 2008 82 89
41. J.M. Simard, T.A. Kent, M. Chen, K.V. Tarasov, and V. Gerzanich Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications Lancet Neurol. 6 2007 258 268 (Pubitemid 46228081)
42. K. Sinha, G. Chaudhary, and Y.K. Gupta Protective effect of resveratrol against oxidative stress in middle cerebral artery occlusion model of stroke in rats Life Sci. 71 2002 655 665 (Pubitemid 34628827)
43. A. Suzuki, A. Fujii, N. Yamamoto, M. Yamamoto, H. Ohminami, A. Kameyama, Y. Shibuya, Y. Nishizawa, I. Tokimitsu, and I. Saito Improvement of hypertension and vascular dysfunction by hydroxyhydroquinone-free coffee in a genetic model of hypertension FEBS Lett. 580 2006 2317 2322
44. A. Suzuki, N. Yamamoto, H. Jokura, M. Yamamoto, A. Fujii, I. Tokimitsu, and I. Saito Chlorogenic acid attenuates hypertension and improves endothelial function in spontaneously hypertensive rats J. Hypertens. 24 2006 1065 1073 (Pubitemid 43772314)
45. A. Tamura, D.I. Graham, J. McCulloch, and G.M. Teasdale Focal cerebral ischaemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion J. Cereb. Blood Flow Metab. 1 1981 53 60 (Pubitemid 12230166)
46. X.H. Xu, S.M. Zhang, W.M. Yan, X.R. Li, H.Y. Zhang, and X.X. Zheng Development of cerebral infarction, apoptotic cell death and expression of X-chromosome-linked inhibitor of apoptosis protein following focal cerebral ischemia in rats Life Sci. 78 2006 704 712
47. Y. Yang, E. Candelario-Jalil, J.F. Thompson, E. Cuadrado, E.Y. Estrada, A. Rosell, J. Montaner, and G.A. Rosenberg Increased intranuclear matrix metalloproteinase activity in neurons interferes with oxidative DNA repair in focal cerebral ischemia J. Neurochem. 112 2009 134 149