Manifold beneficial effects of acetyl salicylic acid and nonsteroidal anti-inflammatory drugs on sepsis

Intensive Care Medicine

Volumn 38, Issue 8, 2012, Pages 1249-1257

  Eisen, Damon P ^a  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Aspirin; Aspirin triggered lipoxins; Mortality Introduction; NF B; NSAID; Sepsis

Indexed keywords

ACETYLSALICYLIC ACID; ANTITHROMBOCYTIC AGENT; CLOPIDOGREL; CYCLOOXYGENASE 2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IBUPROFEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOMETACIN; LACTIC ACID; LIPOPOLYSACCHARIDE; LIPOXIN; NONSTEROID ANTIINFLAMMATORY AGENT; PLACEBO; PROSTACYCLIN; THROMBOXANE;

ABSENCE OF SIDE EFFECTS; ACUTE LUNG INJURY; ANTIINFLAMMATORY ACTIVITY; BACTERIAL ENDOCARDITIS; BACTERIAL VIRULENCE; BLEEDING; COST EFFECTIVENESS ANALYSIS; DRUG ABSORPTION; DRUG MECHANISM; ENDOTOXEMIA; GASTROINTESTINAL HEMORRHAGE; HUMAN; INTENSIVE CARE; KIDNEY DISEASE; LOW DRUG DOSE; LUNG ALVEOLUS MACROPHAGE; MEDIATOR RELEASE; MORTALITY; NEUTROPHIL; NONHUMAN; REVIEW; SEPSIS; SEPTIC SHOCK; STAPHYLOCOCCUS INFECTION; THROMBOCYTE ACTIVATION; THROMBOCYTOPENIA;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INFLAMMATION; LIPOXINS; NF-KAPPA B; SEPSIS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84864276838     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-012-2570-8     Document Type: Review

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