메뉴 건너뛰기




Volumn 101, Issue 1, 2000, Pages 78-85

Staphylococcal α-toxin provokes coronary vasoconstriction and loss in myocardial contractility in perfused rat hearts: Role of thromboxane generation

Author keywords

Contractility; Toxins; Vasoconstriction

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; APAFANT; CREATINE KINASE; DALTROBAN; INDOMETACIN; LACTATE DEHYDROGENASE; LEUKOTRIENE; LIPOXYGENASE INHIBITOR; N(G) METHYLARGININE; NITRIC OXIDE SYNTHASE INHIBITOR; NORDIHYDROGUAIARETIC ACID; PHENTOLAMINE; POTASSIUM; PROSTACYCLIN; STAPHYLOCOCCUS ALPHA TOXIN; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; THROMBOXANE A2; THROMBOXANE RECEPTOR BLOCKING AGENT;

EID: 17344376953     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.101.1.78     Document Type: Article
Times cited : (56)

References (37)
  • 1
    • 0027920980 scopus 로고
    • Pathogenic mechanisms of septic shock
    • Parrillo JE. Pathogenic mechanisms of septic shock. N Engl J Med. 1993; 328:1471-1477.
    • (1993) N Engl J Med , vol.328 , pp. 1471-1477
    • Parrillo, J.E.1
  • 2
    • 0026048714 scopus 로고
    • The pathogenesis of sepsis
    • Bone RC. The pathogenesis of sepsis. Ann Intern Med. 1991;115: 457-469.
    • (1991) Ann Intern Med , vol.115 , pp. 457-469
    • Bone, R.C.1
  • 3
    • 0012680550 scopus 로고
    • Clinical manifestations of cardiovascular dysfunctions in sepsis
    • Schlag G, Redl H, eds. Berlin, Heidelberg: Springer-Verlag
    • Kumar A, Parrillo JE. Clinical manifestations of cardiovascular dysfunctions in sepsis. In: Schlag G, Redl H, eds. Pathophysiology of Shock, Sepsis, and Organ Failure. Berlin, Heidelberg: Springer-Verlag; 1993: 859-881.
    • (1993) Pathophysiology of Shock, Sepsis, and Organ Failure , pp. 859-881
    • Kumar, A.1    Parrillo, J.E.2
  • 4
    • 0025060845 scopus 로고
    • Right ventricular dysfunction and dilation, similar to left ventricular changes, characterize the cardiac depression of septic shock in humans
    • Parker MM, McCarthy KE, Ognibene FP. Right ventricular dysfunction and dilation, similar to left ventricular changes, characterize the cardiac depression of septic shock in humans. Chest. 1990;97:126-131.
    • (1990) Chest , vol.97 , pp. 126-131
    • Parker, M.M.1    McCarthy, K.E.2    Ognibene, F.P.3
  • 5
    • 0026752413 scopus 로고
    • The cardiodepressant and vasodepressant effects of tumor necrosis factor in rat isolated atrial and aortic tissues
    • Foulkes R, Shaw S. The cardiodepressant and vasodepressant effects of tumor necrosis factor in rat isolated atrial and aortic tissues. Br J Pharmacol. 1992;106:942-947.
    • (1992) Br J Pharmacol , vol.106 , pp. 942-947
    • Foulkes, R.1    Shaw, S.2
  • 7
    • 0029975877 scopus 로고    scopus 로고
    • Tumor necrosis factor-α and interleukin 1β are responsible for in vitro myocardial cell depression induced by human septic shock serum
    • Kumar A, Thota V, Dee L, Olson J, Uretz E, Parrillo JE. Tumor necrosis factor-α and interleukin 1β are responsible for in vitro myocardial cell depression induced by human septic shock serum. J Exp Med. 1996;183: 949-958.
    • (1996) J Exp Med , vol.183 , pp. 949-958
    • Kumar, A.1    Thota, V.2    Dee, L.3    Olson, J.4    Uretz, E.5    Parrillo, J.E.6
  • 8
    • 0027225229 scopus 로고
    • Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium
    • Balligand JL, Ungureanu D, Kelly RA, Kobzik L, Pimental D, Michel T, Smith TW. Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. J Clin Invest. 1993:91;2314-2319.
    • (1993) J Clin Invest , vol.91 , pp. 2314-2319
    • Balligand, J.L.1    Ungureanu, D.2    Kelly, R.A.3    Kobzik, L.4    Pimental, D.5    Michel, T.6    Smith, T.W.7
  • 10
    • 0028895671 scopus 로고
    • Inhibition of nitric oxide synthesis causes ischemia in endotoxemic rats
    • Avontuur JAM, Bruining HA, Ince C. Inhibition of nitric oxide synthesis causes ischemia in endotoxemic rats. Circ Res. 1995;76:418-425.
    • (1995) Circ Res , vol.76 , pp. 418-425
    • Avontuur, J.A.M.1    Bruining, H.A.2    Ince, C.3
  • 11
    • 0027201178 scopus 로고
    • Changes in myocardial blood flow during hyperdynamic sepsis with induced changes in arterial perfusing pressures and metabolic need
    • Raper RF, Sibbald WJ, Hobson J, Neal A, Cheung H. Changes in myocardial blood flow during hyperdynamic sepsis with induced changes in arterial perfusing pressures and metabolic need. Crit Care Med. 1993; 21:1192-1199.
    • (1993) Crit Care Med , vol.21 , pp. 1192-1199
    • Raper, R.F.1    Sibbald, W.J.2    Hobson, J.3    Neal, A.4    Cheung, H.5
  • 12
    • 0025214103 scopus 로고
    • Histologic and ultrastructural changes in nonpulmonary organs during early hyperdynamic sepsis
    • Hersch M, Gnidec AA, Bersten AD, Troster M, Rutledge FS, Sibbald WJ. Histologic and ultrastructural changes in nonpulmonary organs during early hyperdynamic sepsis. Surgery. 1990;107:397-410.
    • (1990) Surgery , vol.107 , pp. 397-410
    • Hersch, M.1    Gnidec, A.A.2    Bersten, A.D.3    Troster, M.4    Rutledge, F.S.5    Sibbald, W.J.6
  • 15
    • 0002539868 scopus 로고
    • Microbial toxins: Role in the pathogenesis of septic shock and multi organ failure
    • Bihari DJ, Cerra FB, eds. Fullerton, Calif: Society of Critical Care Medicine
    • Danner RL, Suffredini AF, Natanson C, Parrillo JE. Microbial toxins: role in the pathogenesis of septic shock and multi organ failure. In: Bihari DJ, Cerra FB, eds. Multiple Organ Failure. Fullerton, Calif: Society of Critical Care Medicine; 1989:151-191.
    • (1989) Multiple Organ Failure , pp. 151-191
    • Danner, R.L.1    Suffredini, A.F.2    Natanson, C.3    Parrillo, J.E.4
  • 17
    • 0026670245 scopus 로고
    • Staphylococcal alpha-toxin: A study with chronically instrumented awake sheep
    • Harshmann S, Lefferts PL, Snapper JR. Staphylococcal alpha-toxin: a study with chronically instrumented awake sheep. Infect Immun. 1992; 60:3489-3496.
    • (1992) Infect Immun , vol.60 , pp. 3489-3496
    • Harshmann, S.1    Lefferts, P.L.2    Snapper, J.R.3
  • 18
    • 0024802616 scopus 로고
    • Staphylococcal alpha toxin induced cardiac dysfunction
    • Adamo P, Taylor PB, Fackrell HB. Staphylococcal alpha toxin induced cardiac dysfunction. Can J Cardiol. 1989;5:395-400.
    • (1989) Can J Cardiol , vol.5 , pp. 395-400
    • Adamo, P.1    Taylor, P.B.2    Fackrell, H.B.3
  • 19
    • 0025363228 scopus 로고
    • Effects of Escherichia coli hemolysin on human monocytes
    • Bhakdi S, Muhly M, Korom S, Schmidt G. Effects of Escherichia coli hemolysin on human monocytes. J Clin Invest. 1990;85:1746-1753.
    • (1990) J Clin Invest , vol.85 , pp. 1746-1753
    • Bhakdi, S.1    Muhly, M.2    Korom, S.3    Schmidt, G.4
  • 22
    • 0023086182 scopus 로고
    • Damage to mammalian cells by proteins that form transmembrane pores
    • Bhakdi S, Traum-Jensen J. Damage to mammalian cells by proteins that form transmembrane pores. Rev Physiol Biochem Pharmacol. 1987;107: 147-223.
    • (1987) Rev Physiol Biochem Pharmacol , vol.107 , pp. 147-223
    • Bhakdi, S.1    Traum-Jensen, J.2
  • 23
    • 0023901550 scopus 로고
    • Damage to cell membranes by pore-forming bacterial cytolysins
    • Bhakdi S, Traum-Jensen J. Damage to cell membranes by pore-forming bacterial cytolysins. Prog Allergy. 1988;40:1-43.
    • (1988) Prog Allergy , vol.40 , pp. 1-43
    • Bhakdi, S.1    Traum-Jensen, J.2
  • 24
    • 0025787798 scopus 로고
    • Alpha-toxin of Staphylococcus aureus
    • Bhakdi S, Traum-Jensen J. Alpha-toxin of Staphylococcus aureus. Microbiol Rev. 1991;55:733-751.
    • (1991) Microbiol Rev , vol.55 , pp. 733-751
    • Bhakdi, S.1    Traum-Jensen, J.2
  • 25
    • 0029924449 scopus 로고    scopus 로고
    • Molecular architecture of a toxin pore: A 15-residue sequence lines the transmembrane channel of staphylococcal alpha-toxin
    • Valeva A, Weisser A, Walker B, Kehoe M, Bayley H, Bhakdi S, Palmer M. Molecular architecture of a toxin pore: a 15-residue sequence lines the transmembrane channel of staphylococcal alpha-toxin. EMBO J. 1996; 15:1857-1864.
    • (1996) EMBO J , vol.15 , pp. 1857-1864
    • Valeva, A.1    Weisser, A.2    Walker, B.3    Kehoe, M.4    Bayley, H.5    Bhakdi, S.6    Palmer, M.7
  • 26
    • 0025047346 scopus 로고
    • Functional similarity between the haemolysins of Escherichia coli and Morganella morganii
    • Eberspächer B, Hugo F, Pohl M, Bhakdi S. Functional similarity between the haemolysins of Escherichia coli and Morganella morganii. J Med Microbiol. 1990;33:165-170.
    • (1990) J Med Microbiol , vol.33 , pp. 165-170
    • Eberspächer, B.1    Hugo, F.2    Pohl, M.3    Bhakdi, S.4
  • 27
    • 0023238044 scopus 로고
    • The secreted hemolysins of Proteus mirabilis, Proteus vulgaris, and Morganella morganii are genetically related to each other and to the alpha-hemolysin of Escherichia coli
    • Koronakis V, Cross M, Senior B, Koronakis E, Hughes C. The secreted hemolysins of Proteus mirabilis, Proteus vulgaris, and Morganella morganii are genetically related to each other and to the alpha-hemolysin of Escherichia coli. J Bacteriol. 1987;169:1509-1515.
    • (1987) J Bacteriol , vol.169 , pp. 1509-1515
    • Koronakis, V.1    Cross, M.2    Senior, B.3    Koronakis, E.4    Hughes, C.5
  • 28
    • 0023269886 scopus 로고
    • Identification of two different hemolysin determinants in uropathogenic Proteus isolates
    • Welch RA. Identification of two different hemolysin determinants in uropathogenic Proteus isolates. Infect Immun. 1987;55:2183-2190.
    • (1987) Infect Immun , vol.55 , pp. 2183-2190
    • Welch, R.A.1
  • 29
    • 0024421764 scopus 로고
    • Release of interleukin 1β associated with potent action of staphylococcal alpha-toxin on human monocytes
    • Bhakdi S, Muhly M, Korom S, Hugo F. Release of interleukin 1β associated with potent action of staphylococcal alpha-toxin on human monocytes. Infect Immun. 1989;57:3512-3519.
    • (1989) Infect Immun , vol.57 , pp. 3512-3519
    • Bhakdi, S.1    Muhly, M.2    Korom, S.3    Hugo, F.4
  • 30
    • 0021128101 scopus 로고
    • Staphylococcal α-toxin elicits hypertension in isolated rabbit lungs
    • Seeger W, Bauer M, Bhakdi S. Staphylococcal α-toxin elicits hypertension in isolated rabbit lungs. J Clin Invest. 1984;74:849-858.
    • (1984) J Clin Invest , vol.74 , pp. 849-858
    • Seeger, W.1    Bauer, M.2    Bhakdi, S.3
  • 31
    • 0027273245 scopus 로고
    • Staphylococcal α-toxin induced ventilation-perfusion mismatch in isolated blood-free perfused rabbit lungs
    • Walmrath D, Scharmann M, König R, Pilch J, Grimminger F, Seeger W. Staphylococcal α-toxin induced ventilation-perfusion mismatch in isolated blood-free perfused rabbit lungs. J Appl Physiol. 1993;74: 1972-1980.
    • (1993) J Appl Physiol , vol.74 , pp. 1972-1980
    • Walmrath, D.1    Scharmann, M.2    König, R.3    Pilch, J.4    Grimminger, F.5    Seeger, W.6
  • 32
    • 0025641739 scopus 로고
    • Endothelin-1 and platelet activating factor stimulate thromboxane biosynthesis in rat vascular smooth muscle cell
    • Takayasu-Okishio M, Terashita Z, Kondo K. Endothelin-1 and platelet activating factor stimulate thromboxane biosynthesis in rat vascular smooth muscle cell. Biochem Pharmacol. 1990;40:2713-2717.
    • (1990) Biochem Pharmacol , vol.40 , pp. 2713-2717
    • Takayasu-Okishio, M.1    Terashita, Z.2    Kondo, K.3
  • 33
    • 0342993160 scopus 로고
    • Role of endothelium in endothelin-evoked contractions in the rat aorta
    • Taddei S, Vanhoutte PM. Role of endothelium in endothelin-evoked contractions in the rat aorta. Hypertension. 1992;19:117-130.
    • (1992) Hypertension , vol.19 , pp. 117-130
    • Taddei, S.1    Vanhoutte, P.M.2
  • 34
    • 0031571201 scopus 로고    scopus 로고
    • Human endothelial cell activation and mediator release in response to the bacterial exotoxins Escherichia coli hemolysin and staphylococcal α-toxin
    • Grimminger F, Rose F, Sibelius U, Meinhardt M, Pötzsch B, Spriestersbach R, Bhakdi S, Suttorp N, Seeger W. Human endothelial cell activation and mediator release in response to the bacterial exotoxins Escherichia coli hemolysin and staphylococcal α-toxin. J Immunol. 1997; 159:1909-1916.
    • (1997) J Immunol , vol.159 , pp. 1909-1916
    • Grimminger, F.1    Rose, F.2    Sibelius, U.3    Meinhardt, M.4    Pötzsch, B.5    Spriestersbach, R.6    Bhakdi, S.7    Suttorp, N.8    Seeger, W.9
  • 35
    • 0023064356 scopus 로고
    • Mechanism of leukotriene generation in polymorphonuclear leukocytes by staphylococcal alpha-toxin
    • Suttorp N, Seeger W, Zucker-Reimann J, Roka L, Bhakdi S. Mechanism of leukotriene generation in polymorphonuclear leukocytes by staphylococcal alpha-toxin. Infect Immun. 1987;55:104-110.
    • (1987) Infect Immun , vol.55 , pp. 104-110
    • Suttorp, N.1    Seeger, W.2    Zucker-Reimann, J.3    Roka, L.4    Bhakdi, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.