메뉴 건너뛰기




Volumn 65, Issue 11, 1997, Pages 4652-4660

Hyperproduction of alpha-toxin by Staphylococcus aureus results in paradoxically reduced virulence in experimental endocarditis: A host defense role for platelet microbicidal proteins

Author keywords

[No Author keywords available]

Indexed keywords

STAPHYLOCOCCUS ALPHA TOXIN;

EID: 0030862228     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.11.4652-4660.1997     Document Type: Article
Times cited : (104)

References (46)
  • 1
    • 0028094702 scopus 로고
    • Gentamicin-resistant menodione and hemin auxotrophic Staphylococcus aureus persist within cultured endothelial cells
    • Balwit, J. M., P. van Lageveelde, J. M. Vann, and R. A. Proctor. 1994. Gentamicin-resistant menodione and hemin auxotrophic Staphylococcus aureus persist within cultured endothelial cells. J. Infect. Dis. 170:1033-1037.
    • (1994) J. Infect. Dis. , vol.170 , pp. 1033-1037
    • Balwit, J.M.1    Van Lageveelde, P.2    Vann, J.M.3    Proctor, R.A.4
  • 2
    • 0003079139 scopus 로고
    • Lactic dehydrogenase
    • H. U. Bergmeyer (ed.). Academic Press. Inc., New York, N.Y.
    • Bergmeyer, H. U., E. Bernt, and B. Hess. 1965. Lactic dehydrogenase. p. 736-741. In H. U. Bergmeyer (ed.). Methods of enzymatic analysis. Academic Press. Inc., New York, N.Y.
    • (1965) Methods of Enzymatic Analysis , pp. 736-741
    • Bergmeyer, H.U.1    Bernt, E.2    Hess, B.3
  • 3
    • 0024265414 scopus 로고
    • Assay of hemolytic toxins
    • Bernheimer, A. S. W. 1988. Assay of hemolytic toxins. Methods Enzymol. 165:213-217.
    • (1988) Methods Enzymol. , vol.165 , pp. 213-217
    • Bernheimer, A.S.W.1
  • 5
    • 0025787798 scopus 로고
    • Alpha-toxin of Staphylococcus aureus
    • Bhakdi, S., and J. Tranum-Jensen. 1991. Alpha-toxin of Staphylococcus aureus. Microbiol. Rev. 55:733-751.
    • (1991) Microbiol. Rev. , vol.55 , pp. 733-751
    • Bhakdi, S.1    Tranum-Jensen, J.2
  • 6
    • 0024341103 scopus 로고
    • Roles of alpha-toxin and beta-toxin in virulence of Staphylococcus aureus for the mouse mammary
    • Bramley, A. J., A. H. Patel, M. O'Reilly, R. Foster, and I. J. Foster. 1989. Roles of alpha-toxin and beta-toxin in virulence of Staphylococcus aureus for the mouse mammary. gland Infect Immun 57:2489-2494.
    • (1989) Gland Infect Immun , vol.57 , pp. 2489-2494
    • Bramley, A.J.1    Patel, A.H.2    O'Reilly, M.3    Foster, R.4    Foster, I.J.5
  • 7
    • 0028200916 scopus 로고
    • Corneal virulence of Staphylococcus aureus roles of alpha-toxin and protein A in pathogenesis
    • Callegan, M. C., L. S. Engel, J. M. Hill, and R. J. O'Callaghan. 1994. Corneal virulence of Staphylococcus aureus roles of alpha-toxin and protein A in pathogenesis. Infect. Immun. 62:2478-2482.
    • (1994) Infect. Immun. , vol.62 , pp. 2478-2482
    • Callegan, M.C.1    Engel, L.S.2    Hill, J.M.3    O'Callaghan, R.J.4
  • 8
    • 0017264506 scopus 로고
    • Purification of staphylococcal alpha- Toxin by adsorption chromatography on glass
    • Cassidy, P., and S. Harshman 1976. Purification of staphylococcal alpha- toxin by adsorption chromatography on glass. Infect. Immun. 13:982-986.
    • (1976) Infect. Immun. , vol.13 , pp. 982-986
    • Cassidy, P.1    Harshman, S.2
  • 9
    • 0015953374 scopus 로고
    • Biologic properties of staphylococcal alpha-toxin
    • Cassidy, P., H. R. Six, and S. Harshman. 1974. Biologic properties of staphylococcal alpha-toxin. Biochim. Biophys. Acta 332:413-423.
    • (1974) Biochim. Biophys. Acta , vol.332 , pp. 413-423
    • Cassidy, P.1    Six, H.R.2    Harshman, S.3
  • 10
    • 0028173022 scopus 로고
    • Diminished virulence of a sar lagr mutant of Staphylococcus aureus in the rabbit model of endocarditis
    • Cheung, A. L., K. J. Eberhardt, E. Chung, M. R. Yeaman, P. M. Sullam, M. D. Ramos, and A. S. Bayer. 1994. Diminished virulence of a sar lagr mutant of Staphylococcus aureus in the rabbit model of endocarditis. J. Clin. Invest. 94:1815-1822.
    • (1994) J. Clin. Invest. , vol.94 , pp. 1815-1822
    • Cheung, A.L.1    Eberhardt, K.J.2    Chung, E.3    Yeaman, M.R.4    Sullam, P.M.5    Ramos, M.D.6    Bayer, A.S.7
  • 11
    • 0028116666 scopus 로고
    • A method to isolate RNA from gram-positive bacteria and mycobacteria
    • Cheung, A. L., K. Eberhardt, and V. A. Fischetti. 1994. A method to isolate RNA from gram-positive bacteria and mycobacteria. Anal. Biochem. 222: 511-514.
    • (1994) Anal. Biochem. , vol.222 , pp. 511-514
    • Cheung, A.L.1    Eberhardt, K.2    Fischetti, V.A.3
  • 12
    • 0026638833 scopus 로고
    • Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr
    • Cheung, A. L., J. M. Koomey, C. A. Butler, S. J. Projan, and V. A. Fischetti. 1992. Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr. Proc. Natl. Acad. Sci. USA 89:6462-6466.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 6462-6466
    • Cheung, A.L.1    Koomey, J.M.2    Butler, C.A.3    Projan, S.J.4    Fischetti, V.A.5
  • 13
    • 0028318256 scopus 로고
    • Cloning and sequencing of sarA: A gene required for the expression of agr
    • Cheung, A. L., and S. J. Projan. 1994. Cloning and sequencing of sarA: a gene required for the expression of agr. J. Bacteriol. 176:4168-4172.
    • (1994) J. Bacteriol. , vol.176 , pp. 4168-4172
    • Cheung, A.L.1    Projan, S.J.2
  • 14
    • 0028269858 scopus 로고
    • Role of the sar locus of Staphylococcus aureus in induction of endocarditis in rabbits
    • Cheung, A. L., M. K. Yeaman, P. M. Sullam, M. D. Wilt, and A. S. Bayer. 1994. Role of the sar locus of Staphylococcus aureus in induction of endocarditis in rabbits. Infect. Immun. 62:1719-1725.
    • (1994) Infect. Immun. , vol.62 , pp. 1719-1725
    • Cheung, A.L.1    Yeaman, M.K.2    Sullam, P.M.3    Wilt, M.D.4    Bayer, A.S.5
  • 15
    • 0028178609 scopus 로고
    • Regulation of α- And β-hemolysins by the sar locus of Staphylococcus aureus
    • Cheung, A. L., and P. Ying. 1994. Regulation of α- and β-hemolysins by the sar locus of Staphylococcus aureus. J. Bacteriol. 176:580-585.
    • (1994) J. Bacteriol. , vol.176 , pp. 580-585
    • Cheung, A.L.1    Ying, P.2
  • 16
    • 0028942217 scopus 로고
    • Involvement of bacterial factors from thrombin-stimulated platelets in clearance of adherent viridans streptococci in experimental infective endocarditis
    • Dankert, J., J. van der Werff, S. A. J. Zaat, W. Joldersma, D. Klein, and J. Hess. 1995. Involvement of bacterial factors from thrombin-stimulated platelets in clearance of adherent viridans streptococci in experimental infective endocarditis. Infect. Immun. 63:663-671.
    • (1995) Infect. Immun. , vol.63 , pp. 663-671
    • Dankert, J.1    Van Der Werff, J.2    Zaat, S.A.J.3    Joldersma, W.4    Klein, D.5    Hess, J.6
  • 17
    • 0030760775 scopus 로고    scopus 로고
    • Phenotypic resistance to thrombin-induced platelet microbicidal protein in vitro is correlated with enhanced virulence in experimental endocarditis due to Staphylococcus aureus
    • Dhawan, V. K., M. R. Yeaman, A. L. Cheung, E. Kim, P. M. Sullam, and A. S. Bayer. 1997. Phenotypic resistance to thrombin-induced platelet microbicidal protein in vitro is correlated with enhanced virulence in experimental endocarditis due to Staphylococcus aureus. Infect. Immun. 65:3293-3299.
    • (1997) . Infect. Immun. , vol.65 , pp. 3293-3299
    • Dhawan, V.K.1    Yeaman, M.R.2    Cheung, A.L.3    Kim, E.4    Sullam, P.M.5    Bayer, A.S.6
  • 18
    • 0023901923 scopus 로고
    • Staphylococcus aureus induces tissue factor expression in cultured human cardiac valve endothelium
    • Drake, T. A., and M. Pang. 1988. Staphylococcus aureus induces tissue factor expression in cultured human cardiac valve endothelium. J. Infect. Dis. 157:749-756.
    • (1988) J. Infect. Dis. , vol.157 , pp. 749-756
    • Drake, T.A.1    Pang, M.2
  • 19
    • 0024590717 scopus 로고
    • Effects of interleukin-1, lipopolysaccharide. and streptococci on procoagulant activity of cultured human cardiac valve endothelial and stromal cells
    • Drake, T. A., and M. Pang. 1989. Effects of interleukin-1, lipopolysaccharide. and streptococci on procoagulant activity of cultured human cardiac valve endothelial and stromal cells. Infect. Immun. 57:507-512.
    • (1989) Infect. Immun. , vol.57 , pp. 507-512
    • Drake, T.A.1    Pang, M.2
  • 20
    • 0016706381 scopus 로고
    • Experimental bacterial endocarditis. IV. Structure and evolution of the very early lesions
    • Durack, D. T. 1975. Experimental bacterial endocarditis. IV. Structure and evolution of the very early lesions. J. Clin. Pathol. 45:81-89.
    • (1975) J. Clin. Pathol. , vol.45 , pp. 81-89
    • Durack, D.T.1
  • 21
    • 0015296827 scopus 로고
    • Experimental bacterial endocarditis. I. Colonization of a sterile vegetation
    • Durack, D. T., and P. B. Beeson. 1972. Experimental bacterial endocarditis. I. Colonization of a sterile vegetation. Br. J. Exp. Pathol. 53:44-49.
    • (1972) Br. J. Exp. Pathol. , vol.53 , pp. 44-49
    • Durack, D.T.1    Beeson, P.B.2
  • 23
    • 0026468085 scopus 로고
    • The platelet interactivity phenotype of Streptococcus sanguis influences the course of experimental endocarditis
    • Herzberg, M. C., G. D. MacFarlane, K. E. Gong, N. N. Amstrong, A. R. Witt, P. R. Erickson, and M. W. Meyer. 1992. The platelet interactivity phenotype of Streptococcus sanguis influences the course of experimental endocarditis. Infect. Immun. 60:4809-4818.
    • (1992) Infect. Immun. , vol.60 , pp. 4809-4818
    • Herzberg, M.C.1    MacFarlane, G.D.2    Gong, K.E.3    Amstrong, N.N.4    Witt, A.R.5    Erickson, P.R.6    Meyer, M.W.7
  • 24
    • 0029092465 scopus 로고
    • Growth of Staphylococcus aureus with nafcillin in vitro induces α-toxin production and increases the lethal activity of sterile broth filtrates in a murine model
    • Kernodle, D. S., P. A. McGraw, N. L. Barg, B. E. Menzies, R. K. R. Voladri, and S. Harshman. 1995. Growth of Staphylococcus aureus with nafcillin in vitro induces α-toxin production and increases the lethal activity of sterile broth filtrates in a murine model. J. Infect. Dis. 172:410-419.
    • (1995) J. Infect. Dis. , vol.172 , pp. 410-419
    • Kernodle, D.S.1    McGraw, P.A.2    Barg, N.L.3    Menzies, B.E.4    Voladri, R.K.R.5    Harshman, S.6
  • 25
    • 0002014616 scopus 로고
    • Agr: A polycistronic locus regulating exoprotein synthesis in Staphylococcus aureus
    • R. P. Novick (ed.). VCH Publishers, New York, N.Y.
    • Kornblum, J., B. Kreiswirth, S. J. Projan, H. Ross, and R. P. Novick. 1990 agr: a polycistronic locus regulating exoprotein synthesis in Staphylococcus aureus. p. 373-402. In R. P. Novick (ed.). Molecular biology of the staphylococci. VCH Publishers, New York, N.Y.
    • (1990) Molecular Biology of the Staphylococci , pp. 373-402
    • Kornblum, J.1    Kreiswirth, B.2    Projan, S.J.3    Ross, H.4    Novick, R.P.5
  • 27
    • 0025779401 scopus 로고
    • Construction of single-copy integration vectors for Staphylococcus aureus
    • Lee, C. Y., S. L. Buranen, and Z. H. Ye. 1991. Construction of single-copy integration vectors for Staphylococcus aureus. Gene 103:101-105.
    • (1991) Gene , vol.103 , pp. 101-105
    • Lee, C.Y.1    Buranen, S.L.2    Ye, Z.H.3
  • 28
    • 0002984126 scopus 로고
    • Pathogenesis of infective endocarditis
    • D. Kaye (ed.). Raven Press. New York. N.Y.
    • Livornese, L. L., Jr., and O. M. Korzeniowski. 1992 Pathogenesis of infective endocarditis, p. 19-35. In D. Kaye (ed.). Infective endocarditis. 2nd ed. Raven Press. New York. N.Y.
    • (1992) Infective Endocarditis. 2nd Ed. , pp. 19-35
    • Livornese Jr., L.L.1    Korzeniowski, O.M.2
  • 29
    • 0028216879 scopus 로고
    • Site-directed mutagenesis of the alpha-toxin gene of Staphylococcus aureus: Role of histidines in toxin activity in vitro and in a murine model
    • Menzies, B. E., and D. S. Kernodle. 1994. Site-directed mutagenesis of the alpha-toxin gene of Staphylococcus aureus: role of histidines in toxin activity in vitro and in a murine model. Infect. Immun. 62:1843-1847.
    • (1994) Infect. Immun. , vol.62 , pp. 1843-1847
    • Menzies, B.E.1    Kernodle, D.S.2
  • 30
    • 0028834487 scopus 로고
    • Role of Staphylococcus aureus coagulase and clumping factor in pathogenesis of experimental endocarditis
    • Moreillon, P., J. Entenza, P. Francioli, D. McDevitt, T. Foster, P. Francois, and P. Vaudaux. 1995. Role of Staphylococcus aureus coagulase and clumping factor in pathogenesis of experimental endocarditis. Infect. Immun. 63: 4738-4743.
    • (1995) Infect. Immun. , vol.63 , pp. 4738-4743
    • Moreillon, P.1    Entenza, J.2    Francioli, P.3    McDevitt, D.4    Foster, T.5    Francois, P.6    Vaudaux, P.7
  • 31
    • 0022513453 scopus 로고
    • Inactivation of the alpha-hemolysin gene of Staphylococcus aureus 8325-4 by site-directed mutagenesis and studies on the expression of its haemolysins
    • O'Rellly, M., J. C. S. de Azavedo, S. Kennedy, and T. J. Foster. 1986. Inactivation of the alpha-hemolysin gene of Staphylococcus aureus 8325-4 by site-directed mutagenesis and studies on the expression of its haemolysins. Microb. Pathog. 1:125-138.
    • (1986) Microb. Pathog. , vol.1 , pp. 125-138
    • O'Rellly, M.1    De Azavedo, J.C.S.2    Kennedy, S.3    Foster, T.J.4
  • 32
    • 1842396267 scopus 로고
    • Transformation of bacterial protoplasts
    • O'Reilly, M., and T. J. Foster. 1988. Transformation of bacterial protoplasts. FEMS Symp. 40:203-204
    • (1988) FEMS Symp. , vol.40 , pp. 203-204
    • O'Reilly, M.1    Foster, T.J.2
  • 33
    • 0007271693 scopus 로고
    • Experimental endocarditis. IL Staphylococcal infection of the aortic valve following placement of a polyethylene catheter in the left side of the heart
    • Perlman, B. B., and L. R. Freedman. 1971 Experimental endocarditis. IL Staphylococcal infection of the aortic valve following placement of a polyethylene catheter in the left side of the heart. Yale J. Biol. Med. 42:394-410.
    • (1971) Yale J. Biol. Med. , vol.42 , pp. 394-410
    • Perlman, B.B.1    Freedman, L.R.2
  • 35
    • 0018144003 scopus 로고
    • Bacterial adherence in the pathogenesis of endocarditis: Interaction of bacterial dextran. platelets and fibrin
    • Scheld, W. M., J. A. Valone, and M. A. Sande. 1978 Bacterial adherence in the pathogenesis of endocarditis: interaction of bacterial dextran. platelets and fibrin. J. Clin. Invest. 68:1394-1404.
    • (1978) J. Clin. Invest. , vol.68 , pp. 1394-1404
    • Scheld, W.M.1    Valone, J.A.2    Sande, M.A.3
  • 36
    • 0030447720 scopus 로고    scopus 로고
    • Structure of staphylococcal α-hemolysin, a heptameric transmembrane pore
    • Song, L., M. R. Hobaugh, C. Shustak, S. Cheley, H. Bayley, and J. K. Gouax, 1996. Structure of staphylococcal α-hemolysin, a heptameric transmembrane pore. Science 274:1859-1866.
    • (1996) Science , vol.274 , pp. 1859-1866
    • Song, L.1    Hobaugh, M.R.2    Shustak, C.3    Cheley, S.4    Bayley, H.5    Gouax, J.K.6
  • 37
    • 0029804179 scopus 로고    scopus 로고
    • Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit endocarditis model
    • Sullam, P. M., A. S. Bayer, W. M. Foss, and A. L. Cheung. 1996. Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit endocarditis model. Infect. Immun. 64:4915-4921.
    • (1996) Infect. Immun. , vol.64 , pp. 4915-4921
    • Sullam, P.M.1    Bayer, A.S.2    Foss, W.M.3    Cheung, A.L.4
  • 39
    • 0002914080 scopus 로고
    • Experimental models of endocarditis
    • D. Kaye (ed.). Raven Press. New York. N.Y.
    • Tunkel, A. R., and W. M. Scheld, 1992. Experimental models of endocarditis. p. 37-56. In D. Kaye (ed.). Infective endocarditis. 2nd ed. Raven Press. New York. N.Y.
    • (1992) Infective Endocarditis. 2nd ed. , pp. 37-56
    • Tunkel, A.R.1    Scheld, W.M.2
  • 40
    • 0023679189 scopus 로고
    • Cytotoxic effects of ingested Staphylococcus aureus on bovine endothelial cells: Role of S. aureus alpha hemolysin
    • Vann, J. M., and R. A. Proctor. 1988. Cytotoxic effects of ingested Staphylococcus aureus on bovine endothelial cells: role of S. aureus alpha hemolysin. Microb. Pathog. 4:443-453.
    • (1988) Microb. Pathog. , vol.4 , pp. 443-453
    • Vann, J.M.1    Proctor, R.A.2
  • 41
    • 0026785678 scopus 로고
    • Assembly of the oligomeric membrane pore formed by staphylococcal α-hemolysin examined by truncation mutagenesis
    • Walker, B., M. Krishnasastry, L. Zorn, and H. Bayley. 1942 Assembly of the oligomeric membrane pore formed by staphylococcal α-hemolysin examined by truncation mutagenesis. J. Biol. Chem. 267:21782-21786.
    • (1942) J. Biol. Chem. , vol.267 , pp. 21782-21786
    • Walker, B.1    Krishnasastry, M.2    Zorn, L.3    Bayley, H.4
  • 42
    • 0030016903 scopus 로고    scopus 로고
    • Influence of agr on fibrinogen binding in Staphylococcus aureus Newman
    • Wolz, C., D. McDevitt, T. J. Foster, and A. L. Cheung. 1996. Influence of agr on fibrinogen binding in Staphylococcus aureus Newman. Infect. Immun. 64:3142-3147.
    • (1996) Infect. Immun. , vol.64 , pp. 3142-3147
    • Wolz, C.1    McDevitt, D.2    Foster, T.J.3    Cheung, A.L.4
  • 43
    • 0028209167 scopus 로고
    • In vitro resistance to platelet microbicidal protein correlates with endocarditis source among staphylococcal isolates
    • Wu, T., M. R. Yeaman, and A. S. Bayer. 1994. In vitro resistance to platelet microbicidal protein correlates with endocarditis source among staphylococcal isolates. Antimicrob. Agents Chemother. 38:729-732.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 729-732
    • Wu, T.1    Yeaman, M.R.2    Bayer, A.S.3
  • 44
    • 0026523731 scopus 로고
    • Partial purification and staphylocidal activity of thrombin-induced platelet microbicidal protein
    • Yeaman, M. R., S. M. Puentes, D. C. Norman, and A. S. Bayer. 1992. Partial purification and staphylocidal activity of thrombin-induced platelet microbicidal protein. Infect. Immun. 60:1202-1209.
    • (1992) Infect. Immun. , vol.60 , pp. 1202-1209
    • Yeaman, M.R.1    Puentes, S.M.2    Norman, D.C.3    Bayer, A.S.4
  • 45
    • 0031020085 scopus 로고    scopus 로고
    • Purification and antimicrobial activities of rabbit platelet microbicidal proteins
    • Yeaman, M. R., Y.-Q. Tang, A. J. Shen, A. S. Bayer, and M. E. Selsted. 1997. Purification and antimicrobial activities of rabbit platelet microbicidal proteins. Infect. Immun. 65:1023-1031.
    • (1997) Infect. Immun. , vol.65 , pp. 1023-1031
    • Yeaman, M.R.1    Tang, Y.-Q.2    Shen, A.J.3    Bayer, A.S.4    Selsted, M.E.5
  • 46
    • 0029964527 scopus 로고    scopus 로고
    • Resistance to platelet microbicidal protein (tPMP) results in increased severity of experimental Candida albicans endocarditis
    • Yeaman, M. R., S. S. Soldan, M. A. Ghannoum, J. E. Edwards, Jr., S. G. Filler, and A. S. Bayer. 1996. Resistance to platelet microbicidal protein (tPMP) results in increased severity of experimental Candida albicans endocarditis. Infect. Immun. 54:1379-1384.
    • (1996) Infect. Immun. , vol.54 , pp. 1379-1384
    • Yeaman, M.R.1    Soldan, S.S.2    Ghannoum, M.A.3    Edwards Jr., J.E.4    Filler, S.G.5    Bayer, A.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.