Novel curcumin analogue UBS109 potently stimulates osteoblastogenesis and suppresses osteoclastogenesis: Involvement in Smad activation and NF-κB inhibition

Integrative Biology (United Kingdom)

Volumn 4, Issue 8, 2012, Pages 905-913

  Yamaguchi, Masayoshi ^a   Moore, Terry W ^b   Sun, Aiming ^b   Snyder, James P ^b   Shoji, Mamoru ^c  

^a UNIVERSITY OF GEORGIA   (United States)

^b EMORY UNIVERSITY   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENIC PROTEIN 2; CURCUMIN; ECMN 909; EF 31; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; SMAD PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UBS 109; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; ENZYME ACTIVITY; MINERALIZATION; MOLECULAR WEIGHT; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOCLASTOGENESIS; PRIORITY JOURNAL;

ANIMALS; BONE AND BONES; CELL AGING; CELL DIFFERENTIATION; CELL LINE; CURCUMIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; GENE EXPRESSION REGULATION; LUCIFERASES; MICE; MODELS, CHEMICAL; NF-KAPPA B; NIH 3T3 CELLS; OSTEOBLASTS; OSTEOCLASTS; PIPERIDONES; RANK LIGAND; SIGNAL TRANSDUCTION; SMAD4 PROTEIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84864237486     PISSN: 17579694     EISSN: 17579708     Source Type: Journal    
DOI: 10.1039/c2ib20045g     Document Type: Article

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