Protective effects of curcumin against hepatic fibrosis induced by carbon tetrachloride: Modulation of high-mobility group box 1, Toll-like receptor 4 and 2 expression

Food and Chemical Toxicology

Volumn 50, Issue 9, 2012, Pages 3343-3351

  Tu, Chuan tao ^a   Yao, Qun yan ^a   Xu, Bei li ^a   Wang, Ji yao ^a   Zhou, Chao hui ^a   Zhang, Shun cai ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Curcumin; High mobility group box 1; Inflammation; Liver fibrosis; Toll like receptors; Tumor necrosis factor

Indexed keywords

CARBON TETRACHLORIDE; COLLAGEN; COLLAGEN TYPE 3; COLLAGEN TYPE 3 ALPHA1; CURCUMIN; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; EXTRACELLULAR MATRIX; GENE EXPRESSION; HEPATITIS; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LIVER FIBROSIS; LIVER FUNCTION TEST; LIVER PROTECTION; MALE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; STELLATE CELL; TOXIC HEPATITIS; TREATMENT DURATION; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; CARBON TETRACHLORIDE; CURCUMIN; DNA PRIMERS; HMGB1 PROTEIN; LIVER CIRRHOSIS; MALE; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

RATTUS;

EID: 84864125510     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.05.050     Document Type: Article

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