Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation

Journal of Biological Chemistry

Volumn 287, Issue 30, 2012, Pages 25292-25302

  Wu, Chih Hsien ^a   Tang, Sheau Chung ^a   Wang, Po Hui ^a,b   Lee, Huei ^a   Ko, Jiunn Liang ^a,b  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL-CELL JUNCTIONS; CRITICAL EVENTS; DIFFERENTIATION MARKERS; DNA METHYLTRANSFERASES; DOWN-REGULATION; E-CADHERINS; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; HUMAN BRONCHIAL EPITHELIAL CELLS; HYPERMETHYLATION; LUNG CARCINOGENESIS; LUNG FIBROSIS; N-ACETYLCYSTEINE; POTENT ANTIOXIDANTS; REACTIVE OXYGEN SPECIES; REAL TIME; TUMOR METASTASIS; UP-REGULATION;

BIOLOGICAL ORGANS; CELL MEMBRANES; NICKEL; OXYGEN; PATHOLOGY; POLYMERASE CHAIN REACTION;

GLYCOPROTEINS;

5 AZA 2' DEOXYCYTIDINE; ACETYLCYSTEINE; FIBRONECTIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NICKEL CHLORIDE; REACTIVE OXYGEN METABOLITE; UVOMORULIN;

ARTICLE; BRONCHUS MUCOSA; CARCINOGENESIS; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; UPREGULATION;

ACETYLCYSTEINE; ANTIGENS, DIFFERENTIATION; AZACITIDINE; BRONCHI; CADHERINS; CELL LINE, TRANSFORMED; DNA METHYLATION; DNA MODIFICATION METHYLASES; ENZYME INHIBITORS; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FIBRONECTINS; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERCELLULAR JUNCTIONS; NICKEL; PULMONARY FIBROSIS; REACTIVE OXYGEN SPECIES; RESPIRATORY MUCOSA;

EID: 84864100255     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.291195     Document Type: Article

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