Ectopically expressed perforin-1 is proapoptotic in tumor cell lines by increasing caspase-3 activity and the nuclear translocation of cytochrome c

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Wang, Li Feng ^a   Wang, Fang ^a   Li, Jun Tang ^a   Wen, Wei Hong ^a   Zhao, Jing ^a   Jia, Lin Tao ^a   Meng, Yan Ling ^a   Cao, Yun Xin ^a   Yao, Li Bo ^a   Chen, Si Yi ^b   Xu, Yan Ming ^c   Yang, An Gang ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 3; CYTOCHROME C; PERFORIN; PERFORIN 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CHROMOSOME CONDENSATION; CONTROLLED STUDY; DNA FRAGMENTATION; ECTOPIC EXPRESSION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION SYSTEM; GROWTH INHIBITION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; PROTEIN TRANSPORT; TRANSIENT EXPRESSION; TUMOR CELL LINE;

APOPTOSIS; APOPTOSIS INDUCING FACTOR; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CYTOCHROMES C; FLUORESCENT ANTIBODY TECHNIQUE; HELA CELLS; HEP G2 CELLS; HUMANS; IN SITU NICK-END LABELING; PERFORIN; PHOSPHATIDYLSERINES;

MUS;

EID: 84864071458     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040639     Document Type: Article

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