Granzyme B delivery via perforin is restricted by size, but not by heparan sulfate-dependent endocytosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 37, 2008, Pages 13799-13804

  Kurschus, Florian C ^a,b   Fellows, Edward ^a   Stegmann, Elisabeth ^a   Jenne, Dieter E ^a  

^a MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^b JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Apoptosis; NK cells; Pore forming protein; Serine protease

Indexed keywords

ANTIBODY; GRANZYME B; GRANZYME B ANTIBODY; HEPARAN SULFATE; MEMBRANE RECEPTOR; PERFORIN; UNCLASSIFIED DRUG;

ARTICLE; CELL VACUOLE; CONTROLLED STUDY; CYTOSOL; ENDOCYTOSIS; HUMAN; HUMAN CELL; NATURAL KILLER CELL; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; APOPTOSIS; CELL LINE; ENDOCYTOSIS; GRANZYMES; HEPARITIN SULFATE; HUMANS; KILLER CELLS, NATURAL; MOLECULAR WEIGHT; MUTATION; PERFORIN; PROTEIN BINDING; PROTEIN TRANSPORT;

EID: 52949152874     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0801724105     Document Type: Article

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