Anti-skin cancer properties of phenolic-rich extract from the pericarp of mangosteen (Garcinia mangostana Linn.)

Food and Chemical Toxicology

Volumn 50, Issue 9, 2012, Pages 3004-3013

  Wang, Jing J ^a   Shi, Qing H ^a,b   Zhang, Wei ^a   Sanderson, Barbara J S ^a  

^a FLINDERS UNIVERSITY   (Australia)

^b TIANJIN UNIVERSITY   (China)

Author keywords

Akt pathway; Apoptosis induction; Cell cycle arrest; Mangosteen; Mitochondrial pathway; Skin cancer

Indexed keywords

ALCOHOL; ANTINEOPLASTIC AGENT; BETA ACTIN; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYTOCHROME C; GREEN TEA EXTRACT; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGOSTEEN PERICARP EXTRACT; MESSENGER RNA; PHENOL DERIVATIVE; PLANT EXTRACT; PROTEIN AKT1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL DAMAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GARCINIA MANGOSTANA; GENE EXPRESSION; HUMAN; HUMAN CELL; KERATINOCYTE; MELANOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; NUCLEOTIDE SEQUENCE; PERICARP; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN CANCER; SKIN CARCINOMA; SKIN FIBROBLAST;

ANTICARCINOGENIC AGENTS; APOPTOSIS; BASE SEQUENCE; CASPASES; CELL CYCLE; CELL LINE, TUMOR; DNA PRIMERS; ENZYME ACTIVATION; GARCINIA MANGOSTANA; HUMANS; PHENOLS; PLANT EXTRACTS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SKIN NEOPLASMS;

GARCINIA MANGOSTANA;

EID: 84864053594     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.06.003     Document Type: Article

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