Correction: From dynamic expression patterns to boundary formation in the presomitic mesoderm (PLoS Computational Biology, (2012), 8, 6, 10.1371/journal.pcbi.1002586);From dynamic expression patterns to boundary formation in the presomitic mesoderm

PLoS Computational Biology

Volumn 8, Issue 6, 2012, Pages

  Tiedemann, Hendrik B ^a   Schneltzer, Elida ^a   Zeiser, Stefan ^b   Hoesel, Bastian ^a   Beckers, Johannes ^a,c   Przemeck, Gerhard K H ^a   de Angelis, Martin Hrabě ^a,c  

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b Kinesis Pharma BV   (Netherlands)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SIGNALING; MAMMALS;

CAUSAL CHAINS; COMPUTATIONAL BIOLOGY; EXPRESSION PATTERNS; GENE REGULATORY NETWORKS; GENES EXPRESSION; IN-SILICO MODELS; PARTIAL ASPECTS; PRESOMITIC MESODERM; SOMITOGENESIS; WNT PATHWAY;

GENE EXPRESSION;

CELL PROTEIN; FIBROBLAST GROWTH FACTOR 8; MESSENGER RNA; NOTCH RECEPTOR; PROTEASOME; PROTEIN DELTA LIKE 1; PROTEIN LFNG; PROTEIN MESP2; PROTEIN RIPPLY2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HES 7; TRANSCRIPTION FACTOR TBX8; UNCLASSIFIED DRUG; WNT3A PROTEIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; FGF8 PROTEIN, MOUSE; HES7 PROTEIN, MOUSE; MESP2 PROTEIN, MOUSE; WNT3A PROTEIN, MOUSE;

ARTICLE; CONCENTRATION (PARAMETERS); CORRELATION COEFFICIENT; EMBRYO DEVELOPMENT; GENE PRODUCT; GENE REGULATORY NETWORK; GROWTH RATE; HALF LIFE TIME; IN VIVO STUDY; MATHEMATICAL MODEL; MESODERM; MOLECULAR DYNAMICS; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; OSCILLATION; PHENOTYPE; PRESOMITIC MESODERM; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA DEGRADATION; SOMITE; SOMITOGENESIS; VALIDATION PROCESS; WNT SIGNALING PATHWAY; ANIMAL; BIOLOGICAL MODEL; BIOLOGICAL RHYTHM; BIOLOGY; COMPUTER SIMULATION; FEEDBACK SYSTEM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MORPHOGENESIS; PHYSIOLOGY; PRENATAL DEVELOPMENT; SIGNAL TRANSDUCTION; VALIDATION STUDY;

MUS; VERTEBRATA;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BIOLOGICAL CLOCKS; BODY PATTERNING; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; FEEDBACK, PHYSIOLOGICAL; FIBROBLAST GROWTH FACTOR 8; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE REGULATORY NETWORKS; MESODERM; MICE; MODELS, BIOLOGICAL; RNA, MESSENGER; SIGNAL TRANSDUCTION; SOMITES; WNT3A PROTEIN;

EID: 84864037235     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1007191     Document Type: Erratum

References (113)

1. Gomez C, Ozbudak EM, Wunderlich J, Baumann D, Lewis J, et al. (2008) Control of segment number in vertebrate embryos. Nature 454: 335-339.
2. Saga Y, Takeda H, (2001) The making of the somite: molecular events in vertebrate segmentation. Nat Rev Genet 2: 835-845.
3. Fortini ME, (2009) Notch signaling: the core pathway and its posttranslational regulation. Dev Cell 16: 633-647.
4. Morimoto M, Takahashi Y, Endo M, Saga Y, (2005) The Mesp2 transcription factor establishes segmental borders by suppressing Notch activity. Nature 435: 354-359.
5. Bessho Y, Hirata H, Masamizu Y, Kageyama R, (2003) Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock. Genes Dev 17: 1451-1456.
6. Ferjentsik Z, Hayashi S, Dale JK, Bessho Y, Herreman A, et al. (2009) Notch is a critical component of the mouse somitogenesis oscillator and is essential for the formation of the somites. PLoS Genet 5: e1000662.
7. Conlon RA, Reaume AG, Rossant J, (1995) Notch1 is required for the coordinate segmentation of somites. Development 121: 1533-1545.
8. Hrabe de Angelis M, McIntyre J 2nd, Gossler A, (1997) Maintenance of somite borders in mice requires the Delta homologue DII1. Nature 386: 717-721.
9. Bessho Y, Sakata R, Komatsu S, Shiota K, Yamada S, et al. (2001) Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev 15: 2642-2647.
10. Shifley ET, Vanhorn KM, Perez-Balaguer A, Franklin JD, Weinstein M, et al. (2008) Oscillatory lunatic fringe activity is crucial for segmentation of the anterior but not posterior skeleton. Development 135: 899-908.
11. Stauber M, Sachidanandan C, Morgenstern C, Ish-Horowicz D, (2009) Differential axial requirements for lunatic fringe and Hes7 transcription during mouse somitogenesis. PLoS ONE 4: e7996.
12. Dubrulle J, Pourquie O, (2004) fgf8 mRNA decay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo. Nature 427: 419-422.
13. Aulehla A, Wiegraebe W, Baubet V, Wahl MB, Deng C, et al. (2008) A beta-catenin gradient links the clock and wavefront systems in mouse embryo segmentation. Nat Cell Biol 10: 186-193.
14. Diez del Corral R, Olivera-Martinez I, Goriely A, Gale E, Maden M, et al. (2003) Opposing FGF and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension. Neuron 40: 65-79.
15. Dequeant ML, Glynn E, Gaudenz K, Wahl M, Chen J, et al. (2006) A complex oscillating network of signaling genes underlies the mouse segmentation clock. Science 314: 1595-1598.
16. Dubrulle J, McGrew MJ, Pourquie O, (2001) FGF signaling controls somite boundary position and regulates segmentation clock control of spatiotemporal Hox gene activation. Cell 106: 219-232.
17. Gibb S, Zagorska A, Melton K, Tenin G, Vacca I, et al. (2009) Interfering with Wnt signalling alters the periodicity of the segmentation clock. Dev Biol 330: 21-31.
18. Saga Y, Hata N, Koseki H, Taketo MM, (1997) Mesp2: a novel mouse gene expressed in the presegmented mesoderm and essential for segmentation initiation. Genes Dev 11: 1827-1839.
19. Nakajima Y, Morimoto M, Takahashi Y, Koseki H, Saga Y, (2006) Identification of Epha4 enhancer required for segmental expression and the regulation by Mesp2. Development 133: 2517-2525.
20. Watanabe T, Sato Y, Saito D, Tadokoro R, Takahashi Y, (2009) EphrinB2 coordinates the formation of a morphological boundary and cell epithelialization during somite segmentation. Proc Natl Acad Sci U S A 106: 7467-7472.
21. Yasuhiko Y, Kitajima S, Takahashi Y, Oginuma M, Kagiwada H, et al. (2008) Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2. Development 135: 3511-3519.
22. Oginuma M, Niwa Y, Chapman DL, Saga Y, (2008) Mesp2 and Tbx6 cooperatively create periodic patterns coupled with the clock machinery during mouse somitogenesis. Development 135: 2555-2562.
23. Oginuma M, Takahashi Y, Kitajima S, Kiso M, Kanno J, et al. (2010) The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite. Development 137: 1515-1522.
24. Takahashi J, Ohbayashi A, Oginuma M, Saito D, Mochizuki A, et al. (2010) Analysis of Ripply1/2-deficient mouse embryos reveals a mechanism underlying the rostro-caudal patterning within a somite. Dev Biol 342: 134-145.
25. Niwa Y, Shimojo H, Isomura A, Gonzalez A, Miyachi H, et al. (2011) Different types of oscillations in Notch and Fgf signaling regulate the spatiotemporal periodicity of somitogenesis. Genes Dev 25: 1115-1120.
26. Hester SD, Belmonte JM, Gens JS, Clendenon SG, Glazier JA, (2011) A multi-cell, multi-scale model of vertebrate segmentation and somite formation. PLoS Comput Biol 7: e1002155.
27. Zeiser S, Liebscher HV, Tiedemann H, Rubio-Aliaga I, Przemeck GK, et al. (2006) Number of active transcription factor binding sites is essential for the Hes7 oscillator. Theor Biol Med Model 3: 11.
28. Tiedemann HB, Schneltzer E, Zeiser S, Rubio-Aliaga I, Wurst W, et al. (2007) Cell-based simulation of dynamic expression patterns in the presomitic mesoderm. J Theor Biol 248: 120-129.
29. Maruhashi M, Van De Putte T, Huylebroeck D, Kondoh H, Higashi Y, (2005) Involvement of SIP1 in positioning of somite boundaries in the mouse embryo. Dev Dyn 234: 332-338.
30. Feller J, Schneider A, Schuster-Gossler K, Gossler A, (2008) Noncyclic Notch activity in the presomitic mesoderm demonstrates uncoupling of somite compartmentalization and boundary formation. Genes Dev 22: 2166-2171.
31. Chan T, Kondow A, Hosoya A, Hitachi K, Yukita A, et al. (2007) Ripply2 is essential for precise somite formation during mouse early development. FEBS Lett 581: 2691-2696.
32. Morimoto M, Sasaki N, Oginuma M, Kiso M, Igarashi K, et al. (2007) The negative regulation of Mesp2 by mouse Ripply2 is required to establish the rostro-caudal patterning within a somite. Development 134: 1561-1569.
33. Walker JD, Halliday D, Resnick R, (2008) Fundamental of Physics, 8th edition Hoboken John Wiley & Sons.
34. Gonzalez A, Kageyama R, (2010) Automatic reconstruction of the mouse segmentation network from an experimental evidence database. Biosystems 102: 16-21.
35. Scholpp S, Brand M, (2004) Endocytosis controls spreading and effective signaling range of Fgf8 protein. Curr Biol 14: 1834-1841.
36. Niwa Y, Masamizu Y, Liu T, Nakayama R, Deng CX, et al. (2007) The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock. Dev Cell 13: 298-304.
37. Kageyama R, Masamizu Y, Niwa Y, (2007) Oscillator mechanism of Notch pathway in the segmentation clock. Dev Dyn 236: 1403-1409.
38. Nam Y, Sliz P, Pear WS, Aster JC, Blacklow SC, (2007) Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription. Proc Natl Acad Sci U S A 104: 2103-2108.
39. Lewis J, (2003) Autoinhibition with transcriptional delay: a simple mechanism for the zebrafish somitogenesis oscillator. Curr Biol 13: 1398-1408.
40. Monk NA, (2003) Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays. Curr Biol 13: 1409-1413.
41. Goodwin BC, (1965) Oscillatory behavior in enzymatic control processes. Adv Enzyme Regul 3: 425-438.
42. Murray JD, (2002) Mathematical biology, 3rd ed New York Springer.
43. Uriu K, Morishita Y, Iwasa Y, (2009) Traveling wave formation in vertebrate segmentation. J Theor Biol 257: 385-396.
44. Goldbeter A, Pourquie O, (2008) Modeling the segmentation clock as a network of coupled oscillations in the Notch, Wnt and FGF signaling pathways. J Theor Biol 252: 574-585.
45. Audibert A, Weil D, Dautry F, (2002) In vivo kinetics of mRNA splicing and transport in mammalian cells. Mol Cell Biol 22: 6706-6718.
46. Takebayashi K, Sasai Y, Sakai Y, Watanabe T, Nakanishi S, et al. (1994) Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements. J Biol Chem 269: 5150-5156.
47. Bessho Y, Miyoshi G, Sakata R, Kageyama R, (2001) Hes7: a bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm. Genes Cells 6: 175-185.
48. Chen J, Kang L, Zhang N, (2005) Negative feedback loop formed by Lunatic fringe and Hes7 controls their oscillatory expression during somitogenesis. Genesis 43: 196-204.
49. Bernard S, Cajavec B, Pujo-Menjouet L, Mackey MC, Herzel H, (2006) Modelling transcriptional feedback loops: the role of Gro/TLE1 in Hes1 oscillations. Philos Transact A Math Phys Eng Sci 364: 1155-1170.
50. Rida PC, Le Minh N, Jiang YJ, (2004) A Notch feeling of somite segmentation and beyond. Dev Biol 265: 2-22.
51. Galceran J, Sustmann C, Hsu SC, Folberth S, Grosschedl R, (2004) LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis. Genes Dev 18: 2718-2723.
52. Hofmann M, Schuster-Gossler K, Watabe-Rudolph M, Aulehla A, Herrmann BG, et al. (2004) WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos. Genes Dev 18: 2712-2717.
53. White PH, Chapman DL, (2005) Dll1 is a downstream target of Tbx6 in the paraxial mesoderm. Genesis 42: 193-202.
54. Le Bras S, Loyer N, Le Borgne R, (2011) The multiple facets of ubiquitination in the regulation of notch signaling pathway. Traffic 12: 149-161.
55. Jin YH, Kim H, Oh M, Ki H, Kim K, (2009) Regulation of Notch1/NICD and Hes1 expressions by GSK-3alpha/beta. Mol Cells 27: 15-19.
56. MacDonald BT, Tamai K, He X, (2009) Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 17: 9-26.
57. Hirata H, Yoshiura S, Ohtsuka T, Bessho Y, Harada T, et al. (2002) Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop. Science 298: 840-843.
58. Hirata H, Bessho Y, Kokubu H, Masamizu Y, Yamada S, et al. (2004) Instability of Hes7 protein is crucial for the somite segmentation clock. Nat Genet 36: 750-754.
59. Schweisguth F, (2004) Regulation of notch signaling activity. Curr Biol 14: R129-138.
60. Biris KK, Dunty WC Jr, Yamaguchi TP, (2007) Mouse Ripply2 is downstream of Wnt3a and is dynamically expressed during somitogenesis. Dev Dyn 236: 3167-3172.
61. Dunty WC Jr, Biris KK, Chalamalasetty RB, Taketo MM, Lewandoski M, et al. (2008) Wnt3a/beta-catenin signaling controls posterior body development by coordinating mesoderm formation and segmentation. Development 135: 85-94.
62. Hitachi K, Danno H, Kondow A, Ohnuma K, Uchiyama H, et al. (2008) Physical interaction between Tbx6 and mespb is indispensable for the activation of bowline expression during Xenopus somitogenesis. Biochem Biophys Res Commun 372: 607-612.
63. Bettenhausen B, Hrabe de Angelis M, Simon D, Guenet JL, Gossler A, (1995) Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta. Development 121: 2407-2418.
64. Zeiser S, Muller J, Liebscher V, (2007) Modeling the Hes1 oscillator. J Comput Biol 14: 984-1000.
65. Takashima Y, Ohtsuka T, Gonzalez A, Miyachi H, Kageyama R, (2011) Intronic delay is essential for oscillatory expression in the segmentation clock. Proc Natl Acad Sci U S A 108: 3300-3305.
66. Terry AJ, Sturrock M, Dale JK, Maroto M, Chaplain MA, (2011) A spatio-temporal model of Notch signalling in the zebrafish segmentation clock: conditions for synchronised oscillatory dynamics. PLoS ONE 6: e16980.
67. Hurlbut GD, Kankel MW, Lake RJ, Artavanis-Tsakonas S, (2007) Crossing paths with Notch in the hyper-network. Curr Opin Cell Biol 19: 166-175.
68. Rivett AJ, (1998) Intracellular distribution of proteasomes. Curr Opin Immunol 10: 110-114.
69. Muratani M, Tansey WP, (2003) How the ubiquitin-proteasome system controls transcription. Nat Rev Mol Cell Biol 4: 192-201.
70. Zeiser S, Rivera O, Kuttler C, Hense B, Lasser R, et al. (2008) Oscillations of Hes7 caused by negative autoregulation and ubiquitination. Comput Biol Chem 32: 47-51.
71. Ranganathan P, Vasquez-Del Carpio R, Kaplan FM, Wang H, Gupta A, et al. (2011) Hierarchical phosphorylation within the ankyrin repeat domain defines a phosphoregulatory loop that regulates Notch transcriptional activity. J Biol Chem 286: 28844-28857.
72. Vasquez-Del Carpio R, Kaplan FM, Weaver KL, VanWye JD, Alves-Guerra MC, et al. (2011) Assembly of a Notch transcriptional activation complex requires multimerization. Mol Cell Biol 31: 1396-1408.
73. Krol AJ, Roellig D, Dequeant ML, Tassy O, Glynn E, et al. (2011) Evolutionary plasticity of segmentation clock networks. Development 138: 2783-2792.
74. Eckalbar WL, (2011) Major shifts in the evolution of somitogenesis: the reptile Anolis carolinensis represents a fourth type of segmentation clock among vertebrates. Dev Biol 356: 254.
75. Hayashi S, Shimoda T, Nakajima M, Tsukada Y, Sakumura Y, et al. (2009) Sprouty4, an FGF inhibitor, displays cyclic gene expression under the control of the notch segmentation clock in the mouse PSM. PLoS ONE 4: e5603.
76. Dale JK, Malapert P, Chal J, Vilhais-Neto G, Maroto M, et al. (2006) Oscillations of the snail genes in the presomitic mesoderm coordinate segmental patterning and morphogenesis in vertebrate somitogenesis. Dev Cell 10: 355-366.
77. Pirot P, van Grunsven LA, Marine JC, Huylebroeck D, Bellefroid EJ, (2004) Direct regulation of the Nrarp gene promoter by the Notch signaling pathway. Biochem Biophys Res Commun 322: 526-534.
78. Ishikawa A, Kitajima S, Takahashi Y, Kokubo H, Kanno J, et al. (2004) Mouse Nkd1, a Wnt antagonist, exhibits oscillatory gene expression in the PSM under the control of Notch signaling. Mech Dev 121: 1443-1453.
79. Gibb S, Maroto M, Dale JK, (2010) The segmentation clock mechanism moves up a notch. Trends Cell Biol 20: 593-600.
80. Yu HM, Jerchow B, Sheu TJ, Liu B, Costantini F, et al. (2005) The role of Axin2 in calvarial morphogenesis and craniosynostosis. Development 132: 1995-2005.
81. Serth K, Schuster-Gossler K, Cordes R, Gossler A, (2003) Transcriptional oscillation of lunatic fringe is essential for somitogenesis. Genes Dev 17: 912-925.
82. Dale JK, Maroto M, Dequeant ML, Malapert P, McGrew M, et al. (2003) Periodic notch inhibition by lunatic fringe underlies the chick segmentation clock. Nature 421: 275-278.
83. Shifley ET, Cole SE, (2008) Lunatic fringe protein processing by proprotein convertases may contribute to the short protein half-life in the segmentation clock. Biochim Biophys Acta 1783: 2384-2390.
84. Jiang YJ, Aerne BL, Smithers L, Haddon C, Ish-Horowicz D, et al. (2000) Notch signalling and the synchronization of the somite segmentation clock. Nature 408: 475-479.
85. Elmasri H, Liedtke D, Lucking G, Volff JN, Gessler M, et al. (2004) her7 and hey1, but not lunatic fringe show dynamic expression during somitogenesis in medaka (Oryzias latipes). Gene Expr Patterns 4: 553-559.
86. Horikawa K, Ishimatsu K, Yoshimoto E, Kondo S, Takeda H, (2006) Noise-resistant and synchronized oscillation of the segmentation clock. Nature 441: 719-723.
87. Kobayashi T, Mizuno H, Imayoshi I, Furusawa C, Shirahige K, et al. (2009) The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells. Genes Dev 23: 1870-1875.
88. Hou X, Tashima Y, Stanley P, (2012) Galactose differentially modulates lunatic and manic fringe effects on Delta1-induced NOTCH signaling. J Biol Chem 287: 474-483.
89. Oberg C, Li J, Pauley A, Wolf E, Gurney M, et al. (2001) The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog. J Biol Chem 276: 35847-35853.
90. Zhou BP, Deng J, Xia W, Xu J, Li YM, et al. (2004) Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nat Cell Biol 6: 931-940.
91. Farin HF, Bussen M, Schmidt MK, Singh MK, Schuster-Gossler K, et al. (2007) Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors. J Biol Chem 282: 25748-25759.
92. Farin HF, Mansouri A, Petry M, Kispert A, (2008) T-box protein Tbx18 interacts with the paired box protein Pax3 in the development of the paraxial mesoderm. J Biol Chem 283: 25372-25380.
93. Bussen M, Petry M, Schuster-Gossler K, Leitges M, Gossler A, et al. (2004) The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments. Genes Dev 18: 1209-1221.
94. Rallis C, Pinchin SM, Ish-Horowicz D, (2010) Cell-autonomous integrin control of Wnt and Notch signalling during somitogenesis. Development 137: 3591-3601.
95. Koizumi K, Nakajima M, Yuasa S, Saga Y, Sakai T, et al. (2001) The role of presenilin 1 during somite segmentation. Development 128: 1391-1402.
96. Kusumi K, Mimoto MS, Covello KL, Beddington RS, Krumlauf R, et al. (2004) Dll3 pudgy mutation differentially disrupts dynamic expression of somite genes. Genesis 39: 115-121.
97. Sewell W, Sparrow DB, Smith AJ, Gonzalez DM, Rappaport EF, et al. (2009) Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis. Dev Biol 329: 400-409.
98. Vermot J, Gallego Llamas J, Fraulob V, Niederreither K, Chambon P, et al. (2005) Retinoic acid controls the bilateral symmetry of somite formation in the mouse embryo. Science 308: 563-566.
99. Goldbeter A, Gonze D, Pourquie O, (2007) Sharp developmental thresholds defined through bistability by antagonistic gradients of retinoic acid and FGF signaling. Dev Dyn 236: 1495-1508.
100. Cunningham TJ, Zhao X, Duester G, (2011) Uncoupling of retinoic acid signaling from tailbud development before termination of body axis extension. Genesis 49: 776-783.
101. Ekerot M, Stavridis MP, Delavaine L, Mitchell MP, Staples C, et al. (2008) Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter. Biochem J 412: 287-298.
102. Dequeant ML, Pourquie O, (2008) Segmental patterning of the vertebrate embryonic axis. Nat Rev Genet 9: 370-382.
103. Jorgensen C, Sherman A, Chen GI, Pasculescu A, Poliakov A, et al. (2009) Cell-specific information processing in segregating populations of Eph receptor ephrin-expressing cells. Science 326: 1502-1509.
104. Uriu K, Morishita Y, Iwasa Y, (2010) Random cell movement promotes synchronization of the segmentation clock. Proc Natl Acad Sci U S A 107: 4979-4984.
105. Benazeraf B, Francois P, Baker RE, Denans N, Little CD, et al. (2010) A random cell motility gradient downstream of FGF controls elongation of an amniote embryo. Nature 466: 248-252.
106. Cohen M, Georgiou M, Stevenson NL, Miodownik M, Baum B, (2010) Dynamic filopodia transmit intermittent Delta-Notch signaling to drive pattern refinement during lateral inhibition. Dev Cell 19: 78-89.
107. Riedel-Kruse IH, Muller C, Oates AC, (2007) Synchrony dynamics during initiation, failure, and rescue of the segmentation clock. Science 317: 1911-1915.
108. Sheldon H, Heikamp E, Turley H, Dragovic R, Thomas P, et al. (2010) New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes. Blood 116: 2385-2394.
109. Thiery JP, Acloque H, Huang RY, Nieto MA, (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890.
110. Rifes P, Carvalho L, Lopes C, Andrade RP, Rodrigues G, et al. (2007) Redefining the role of ectoderm in somitogenesis: a player in the formation of the fibronectin matrix of presomitic mesoderm. Development 134: 3155-3165.
111. Julich D, Mould AP, Koper E, Holley SA, (2009) Control of extracellular matrix assembly along tissue boundaries via Integrin and Eph/Ephrin signaling. Development 136: 2913-2921.
112. Jouve C, Palmeirim I, Henrique D, Beckers J, Gossler A, et al. (2000) Notch signalling is required for cyclic expression of the hairy-like gene HES1 in the presomitic mesoderm. Development 127: 1421-1429.
113. Sasaki N, Kiso M, Kitagawa M, Saga Y, (2011) The repression of Notch signaling occurs via the destabilization of mastermind-like 1 by Mesp2 and is essential for somitogenesis. Development 138: 55-64.