Statins affect the presentation of endothelial chemokines by targeting to multivesicular bodies

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Hol, Johanna ^a   Otterdal, Kari ^a   Breland, Unni M ^a   Stang, Espen ^a   Pedersen, Turid M ^a   Hagelsteen, Kathrine ^a   Ranheim, Trine ^a   Kasprzycka, Monika ^a   Halvorsen, Bente ^a   Haraldsen, Guttorm ^a   Aukrust, Pål ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; CD63 ANTIGEN; CHOLESTEROL; CXCL1 CHEMOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FLUINDOSTATIN; GERANYLGERANYL PYROPHOSPHATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; PRAVASTATIN; SIMVASTATIN; SQUALENE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL COMPOSITION; CELL FUNCTION; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG TARGETING; ENDOCYTOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IMMUNOELECTRON MICROSCOPY; INHIBITION KINETICS; ISOPRENYLATION; MULTIVESICULAR BODY; PROTEIN LOCALIZATION; UMBILICAL VEIN ENDOTHELIAL CELL;

ANTIGENS, CD63; CELL COMPARTMENTATION; CHEMOKINE CXCL1; CHEMOKINES; E-SELECTIN; ENDOCYTOSIS; FATTY ACIDS, MONOUNSATURATED; HEPTANOIC ACIDS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INDOLES; INTERLEUKIN-1BETA; INTRACELLULAR SPACE; MULTIVESICULAR BODIES; PRAVASTATIN; PRENYLATION; PYRROLES; SIMVASTATIN; SOLUBILITY; SUBCELLULAR FRACTIONS;

EID: 84864022389     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040673     Document Type: Article

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