Statins control oxidized ldl-mediated histone modifications and gene expression in cultured human endothelial cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 29, Issue 3, 2009, Pages 380-386

  N'Guessan, Philippe Dje ^a   Riediger, Fabian ^a   Vardarova, Kremena ^a   Scharf, Stefanie ^a   Eitel, Julia ^a   Opitz, Bastian ^a   Slevogt, Hortense ^a   Weichert, Wilko ^a   Hocke, Andreas C ^a   Schmeck, Bernd ^a   Suttorp, Norbert ^a   Hippenstiel, Stefan ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Cytokines; Endothelium; HDAC; Histone; Statins

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOKINE; HISTONE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE INHIBITOR; HISTONE H3; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LECTIN; LOW DENSITY LIPOPROTEIN; MEVALONIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; RNA POLYMERASE II; AUTACOID; CCL2 PROTEIN, HUMAN; FLUINDOSTATIN; HDAC1 PROTEIN, HUMAN; HISTONE DEACETYLASE; HISTONE DEACETYLASE-2; HYDROXAMIC ACID; IL8 PROTEIN, HUMAN; INDOLE DERIVATIVE; MONOUNSATURATED FATTY ACID; OLR1 PROTEIN, HUMAN; OXIDIZED LOW DENSITY LIPOPROTEIN; REPRESSOR PROTEIN; SIMVASTATIN; SMALL INTERFERING RNA; TRICHOSTATIN A; VORINOSTAT;

ACETYLATION; ARTICLE; ATHEROSCLEROSIS; CELL CULTURE; CONTROLLED STUDY; DRUG ANTAGONISM; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; LIPID OXIDATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MODIFICATION; CORONARY BLOOD VESSEL; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

CELLS, CULTURED; CHEMOKINE CCL2; CORONARY VESSELS; CYTOKINES; ENDOTHELIAL CELLS; FATTY ACIDS, MONOUNSATURATED; GENE EXPRESSION REGULATION; HISTONE DEACETYLASES; HISTONES; HUMANS; HYDROXAMIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INDOLES; INFLAMMATION MEDIATORS; INTERLEUKIN-8; LIPOPROTEINS, LDL; MEVALONIC ACID; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PROMOTER REGIONS, GENETIC; REPRESSOR PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SCAVENGER RECEPTORS, CLASS E; SIGNAL TRANSDUCTION; SIMVASTATIN;

EID: 61549114350     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.108.178319     Document Type: Article

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