메뉴 건너뛰기




Volumn 46, Issue 2, 2012, Pages 155-165

The role of sodium channels in chronic pain

Author keywords

Chronic pain; Demyelination; Nociception; Nodes of ranvier; Sodium channels

Indexed keywords

ANALGESIC AGENT; SODIUM CHANNEL; SODIUM CHANNEL NAV1.1; SODIUM CHANNEL NAV1.2; SODIUM CHANNEL NAV1.3; SODIUM CHANNEL NAV1.4; SODIUM CHANNEL NAV1.5; SODIUM CHANNEL NAV1.6; SODIUM CHANNEL NAV1.7; SODIUM CHANNEL NAV1.8; SODIUM CHANNEL NAV1.9;

EID: 84864021960     PISSN: 0148639X     EISSN: 10974598     Source Type: Journal    
DOI: 10.1002/mus.23314     Document Type: Review
Times cited : (58)

References (87)
  • 4
    • 0036134357 scopus 로고    scopus 로고
    • Beta subunits: players in neuronal hyperexcitability?
    • Isom LL. Beta subunits: players in neuronal hyperexcitability? Novartis Found Symp 2002; 241: 124-138.
    • (2002) Novartis Found Symp , vol.241 , pp. 124-138
    • Isom, L.L.1
  • 5
    • 33747079860 scopus 로고    scopus 로고
    • Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain
    • Lopez-Santiago LF, Pertin M, Morisod X, Chen C, Hong S, Wiley J, et al. Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain. J Neurosci 2006; 26: 7984-7994.
    • (2006) J Neurosci , vol.26 , pp. 7984-7994
    • Lopez-Santiago, L.F.1    Pertin, M.2    Morisod, X.3    Chen, C.4    Hong, S.5    Wiley, J.6
  • 6
    • 0025273145 scopus 로고
    • Neuron-specific expression of the rat brain type II sodium channel gene is directed by upstream regulatory elements
    • Maue RA, Kraner SD, Goodman RH, Mandel G. Neuron-specific expression of the rat brain type II sodium channel gene is directed by upstream regulatory elements. Neuron 1990; 4: 223-231.
    • (1990) Neuron , vol.4 , pp. 223-231
    • Maue, R.A.1    Kraner, S.D.2    Goodman, R.H.3    Mandel, G.4
  • 7
    • 0031026004 scopus 로고    scopus 로고
    • A single zinc finger motif in the silencing factor REST represses the neural-specific type II sodium channel promoter
    • Tapia-Ramirez J, Eggen BJ, Peral-Rubio MJ, Toledo-Aral JJ, Mandel G. A single zinc finger motif in the silencing factor REST represses the neural-specific type II sodium channel promoter. Proc Natl Acad Sci U S A 1997; 94: 1177-1182.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 1177-1182
    • Tapia-Ramirez, J.1    Eggen, B.J.2    Peral-Rubio, M.J.3    Toledo-Aral, J.J.4    Mandel, G.5
  • 8
    • 0035034213 scopus 로고    scopus 로고
    • Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon
    • Boiko T, Rasband MN, Levinson SR, Caldwell JH, Mandel G, Trimmer JS, et al. Compact myelin dictates the differential targeting of two sodium channel isoforms in the same axon. Neuron 2001; 30: 91-104.
    • (2001) Neuron , vol.30 , pp. 91-104
    • Boiko, T.1    Rasband, M.N.2    Levinson, S.R.3    Caldwell, J.H.4    Mandel, G.5    Trimmer, J.S.6
  • 9
    • 14844298657 scopus 로고    scopus 로고
    • Decrease in inflammatory hyperalgesia by herpes vector-mediated knockdown of Nav1.7 sodium channels in primary afferents
    • Yeomans DC, Levinson SR, Peters MC, Koszowski AG, Tzabazis AZ, Gilly WF, et al. Decrease in inflammatory hyperalgesia by herpes vector-mediated knockdown of Nav1.7 sodium channels in primary afferents. Hum Gene Ther 2005; 16: 271-277.
    • (2005) Hum Gene Ther , vol.16 , pp. 271-277
    • Yeomans, D.C.1    Levinson, S.R.2    Peters, M.C.3    Koszowski, A.G.4    Tzabazis, A.Z.5    Gilly, W.F.6
  • 11
    • 33847168937 scopus 로고    scopus 로고
    • SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes
    • Fertleman CR, Baker MD, Parker KA, Moffatt S, Elmslie FV, Abrahamsen B, et al. SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypes. Neuron 2006; 52: 767-774.
    • (2006) Neuron , vol.52 , pp. 767-774
    • Fertleman, C.R.1    Baker, M.D.2    Parker, K.A.3    Moffatt, S.4    Elmslie, F.V.5    Abrahamsen, B.6
  • 14
    • 0032168726 scopus 로고    scopus 로고
    • Prevalence of chronic benign pain disorder among adults: a review of the literature
    • Verhaak PF, Kerssens JJ, Dekker J, Sorbi MJ, Bensing JM. Prevalence of chronic benign pain disorder among adults: a review of the literature. Pain 1998; 77: 231-239.
    • (1998) Pain , vol.77 , pp. 231-239
    • Verhaak, P.F.1    Kerssens, J.J.2    Dekker, J.3    Sorbi, M.J.4    Bensing, J.M.5
  • 15
    • 0033614664 scopus 로고    scopus 로고
    • Management of chronic pain
    • Ashburn MA, Staats PS. Management of chronic pain. Lancet 1999; 353: 1865-1869.
    • (1999) Lancet , vol.353 , pp. 1865-1869
    • Ashburn, M.A.1    Staats, P.S.2
  • 16
    • 0033535722 scopus 로고    scopus 로고
    • The neurobiology of pain
    • Besson JM. The neurobiology of pain. Lancet 1999; 353: 1610-1615.
    • (1999) Lancet , vol.353 , pp. 1610-1615
    • Besson, J.M.1
  • 17
    • 33745153343 scopus 로고    scopus 로고
    • Immune and inflammatory mechanisms in neuropathic pain
    • Moalem G, Tracey DJ. Immune and inflammatory mechanisms in neuropathic pain. Brain Res Rev 2006; 51: 240-264.
    • (2006) Brain Res Rev , vol.51 , pp. 240-264
    • Moalem, G.1    Tracey, D.J.2
  • 18
    • 70149097762 scopus 로고    scopus 로고
    • Future potential and status of selective sodium channel blockers for the treatment of pain
    • Priest BT. Future potential and status of selective sodium channel blockers for the treatment of pain. Curr Opin Drug Discov Devel 2009; 12: 682-692.
    • (2009) Curr Opin Drug Discov Devel , vol.12 , pp. 682-692
    • Priest, B.T.1
  • 19
    • 34347226327 scopus 로고    scopus 로고
    • Subtype-selective sodium channel blockers promise a new era of pain research
    • Priest BT, Kaczorowski GJ. Subtype-selective sodium channel blockers promise a new era of pain research. Proc Natl Acad Sci U S A 2007; 104: 8205-8206.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 8205-8206
    • Priest, B.T.1    Kaczorowski, G.J.2
  • 20
    • 38649130197 scopus 로고    scopus 로고
    • Sodium channels and nociception: recent concepts and therapeutic opportunities
    • Krafte DS, Bannon AW. Sodium channels and nociception: recent concepts and therapeutic opportunities. Curr Opin Pharmacol 2008; 8: 50-56.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 50-56
    • Krafte, D.S.1    Bannon, A.W.2
  • 21
    • 39249085112 scopus 로고    scopus 로고
    • Na(+) channel blockers for the treatment of pain: context is everything, almost
    • Gold MS. Na(+) channel blockers for the treatment of pain: context is everything, almost. Exp Neurol 2008; 210: 1-6.
    • (2008) Exp Neurol , vol.210 , pp. 1-6
    • Gold, M.S.1
  • 23
    • 77950921542 scopus 로고    scopus 로고
    • Understanding inflammatory pain: ion channels contributing to acute and chronic nociception
    • Linley JE, Rose K, Ooi L, Gamper N. Understanding inflammatory pain: ion channels contributing to acute and chronic nociception. Pflugers Arch 2010; 459: 657-669.
    • (2010) Pflugers Arch , vol.459 , pp. 657-669
    • Linley, J.E.1    Rose, K.2    Ooi, L.3    Gamper, N.4
  • 24
    • 0033955244 scopus 로고    scopus 로고
    • Immunolocalization of SNS/PN3 and NaN/SNS2 sodium channels in human pain states
    • Coward K, Plumpton C, Facer P, Birch R, Carlstedt T, Tate S, et al. Immunolocalization of SNS/PN3 and NaN/SNS2 sodium channels in human pain states. Pain 2000; 85: 41-50.
    • (2000) Pain , vol.85 , pp. 41-50
    • Coward, K.1    Plumpton, C.2    Facer, P.3    Birch, R.4    Carlstedt, T.5    Tate, S.6
  • 25
    • 42949160614 scopus 로고    scopus 로고
    • Changes in the expression of NaV1.7, NaV1.8 and NaV1.9 in a distinct population of dorsal root ganglia innervating the rat knee joint in a model of chronic inflammatory joint pain
    • Strickland IT, Martindale JC, Woodhams PL, Reeve AJ, Chessell IP, McQueen DS. Changes in the expression of NaV1.7, NaV1.8 and NaV1.9 in a distinct population of dorsal root ganglia innervating the rat knee joint in a model of chronic inflammatory joint pain. Eur J Pain 2008; 12: 564-572.
    • (2008) Eur J Pain , vol.12 , pp. 564-572
    • Strickland, I.T.1    Martindale, J.C.2    Woodhams, P.L.3    Reeve, A.J.4    Chessell, I.P.5    McQueen, D.S.6
  • 26
    • 1542498432 scopus 로고    scopus 로고
    • Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain
    • Black JA, Liu S, Tanaka M, Cummins TR, Waxman SG. Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain. Pain 2004; 108: 237-247.
    • (2004) Pain , vol.108 , pp. 237-247
    • Black, J.A.1    Liu, S.2    Tanaka, M.3    Cummins, T.R.4    Waxman, S.G.5
  • 27
    • 0033541574 scopus 로고    scopus 로고
    • Development of inflammatory hypersensitivity and augmentation of sodium channels in rat dorsal root ganglia
    • Gould HJ III, Gould TN, Paul D, England JD, Liu ZP, Reeb SC, et al. Development of inflammatory hypersensitivity and augmentation of sodium channels in rat dorsal root ganglia. Brain Res 1999; 824: 296-299.
    • (1999) Brain Res , vol.824 , pp. 296-299
    • Gould III, H.J.1    Gould, T.N.2    Paul, D.3    England, J.D.4    Liu, Z.P.5    Reeb, S.C.6
  • 28
    • 0344936728 scopus 로고    scopus 로고
    • Rapid sodium channel augmentation in response to inflammation induced by complete Freund's adjuvant
    • Gould HJ III, England JD, Liu ZP, Levinson SR. Rapid sodium channel augmentation in response to inflammation induced by complete Freund's adjuvant. Brain Res 1998; 802: 69-74.
    • (1998) Brain Res , vol.802 , pp. 69-74
    • Gould III, H.J.1    England, J.D.2    Liu, Z.P.3    Levinson, S.R.4
  • 30
    • 0036813714 scopus 로고    scopus 로고
    • Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)-null mice
    • Laird JM, Souslova V, Wood JN, Cervero F. Deficits in visceral pain and referred hyperalgesia in Nav1.8 (SNS/PN3)-null mice. J Neurosci 2002; 22: 8352-8356.
    • (2002) J Neurosci , vol.22 , pp. 8352-8356
    • Laird, J.M.1    Souslova, V.2    Wood, J.N.3    Cervero, F.4
  • 31
    • 0036145275 scopus 로고    scopus 로고
    • Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8
    • Lai J, Gold MS, Kim CS, Bian D, Ossipov MH, Hunter JC, et al. Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8. Pain 2002; 95: 143-152.
    • (2002) Pain , vol.95 , pp. 143-152
    • Lai, J.1    Gold, M.S.2    Kim, C.S.3    Bian, D.4    Ossipov, M.H.5    Hunter, J.C.6
  • 32
    • 21544455502 scopus 로고    scopus 로고
    • Contribution of the tetrodotoxin-resistant voltage-gated sodium channel NaV1.9 to sensory transmission and nociceptive behavior
    • Priest BT, Murphy BA, Lindia JA, Diaz C, Abbadie C, Ritter AM, et al. Contribution of the tetrodotoxin-resistant voltage-gated sodium channel NaV1.9 to sensory transmission and nociceptive behavior. Proc Natl Acad Sci U S A 2005; 102: 9382-9387.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 9382-9387
    • Priest, B.T.1    Murphy, B.A.2    Lindia, J.A.3    Diaz, C.4    Abbadie, C.5    Ritter, A.M.6
  • 33
    • 33845631301 scopus 로고    scopus 로고
    • The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity
    • Amaya F, Wang H, Costigan M, Allchorne AJ, Hatcher JP, Egerton J, et al. The voltage-gated sodium channel Na(v)1.9 is an effector of peripheral inflammatory pain hypersensitivity. J Neurosci 2006; 26: 12852-12860.
    • (2006) J Neurosci , vol.26 , pp. 12852-12860
    • Amaya, F.1    Wang, H.2    Costigan, M.3    Allchorne, A.J.4    Hatcher, J.P.5    Egerton, J.6
  • 34
    • 3042791018 scopus 로고    scopus 로고
    • Ibuprofen blocks changes in Na v 1.7 and 1.8 sodium channels associated with complete Freund's adjuvant-induced inflammation in rat
    • Gould HJ III, England JD, Soignier RD, Nolan P, Minor LD, Liu ZP, et al. Ibuprofen blocks changes in Na v 1.7 and 1.8 sodium channels associated with complete Freund's adjuvant-induced inflammation in rat. J Pain 2004; 5: 270-280.
    • (2004) J Pain , vol.5 , pp. 270-280
    • Gould III, H.J.1    England, J.D.2    Soignier, R.D.3    Nolan, P.4    Minor, L.D.5    Liu, Z.P.6
  • 35
    • 0033985255 scopus 로고    scopus 로고
    • A possible role for nerve growth factor in the augmentation of sodium channels in models of chronic pain
    • Gould HJ III, Gould TN, England JD, Paul D, Liu ZP, Levinson SR. A possible role for nerve growth factor in the augmentation of sodium channels in models of chronic pain. Brain Res 2000; 854: 19-29.
    • (2000) Brain Res , vol.854 , pp. 19-29
    • Gould III, H.J.1    Gould, T.N.2    England, J.D.3    Paul, D.4    Liu, Z.P.5    Levinson, S.R.6
  • 36
    • 18044375589 scopus 로고    scopus 로고
    • Localization of the Nav1.8 sodium channel isoform at nodes of Ranvier in normal human radicular tooth pulp
    • Henry MA, Sorensen HJ, Johnson LR, Levinson SR. Localization of the Nav1.8 sodium channel isoform at nodes of Ranvier in normal human radicular tooth pulp. Neurosci Lett 2005; 380: 32-36.
    • (2005) Neurosci Lett , vol.380 , pp. 32-36
    • Henry, M.A.1    Sorensen, H.J.2    Johnson, L.R.3    Levinson, S.R.4
  • 37
    • 67449135880 scopus 로고    scopus 로고
    • Sodium channel expression and localization at demyelinated sites in painful human dental pulp
    • Henry MA, Luo S, Foley BD, Rzasa RS, Johnson LR, Levinson SR. Sodium channel expression and localization at demyelinated sites in painful human dental pulp. J Pain 2009; 10: 750-758.
    • (2009) J Pain , vol.10 , pp. 750-758
    • Henry, M.A.1    Luo, S.2    Foley, B.D.3    Rzasa, R.S.4    Johnson, L.R.5    Levinson, S.R.6
  • 38
    • 43749121619 scopus 로고    scopus 로고
    • Nav1.7 expression is increased in painful human dental pulp
    • Luo S, Perry GM, Levinson SR, Henry MA. Nav1.7 expression is increased in painful human dental pulp. Mol Pain 2008; 4: 16.
    • (2008) Mol Pain , vol.4 , pp. 16
    • Luo, S.1    Perry, G.M.2    Levinson, S.R.3    Henry, M.A.4
  • 40
    • 34548541493 scopus 로고    scopus 로고
    • Expression of Nav1.9 channels in human dental pulp and trigeminal ganglion
    • Wells JE, Bingham V, Rowland KC, Hatton J. Expression of Nav1.9 channels in human dental pulp and trigeminal ganglion. J Endod 2007; 33: 1172-1176.
    • (2007) J Endod , vol.33 , pp. 1172-1176
    • Wells, J.E.1    Bingham, V.2    Rowland, K.C.3    Hatton, J.4
  • 41
    • 77953124434 scopus 로고    scopus 로고
    • Sodium channel Na v 1.7 immunoreactivity in painful human dental pulp and burning mouth syndrome
    • Beneng K, Renton T, Yilmaz Z, Yiangou Y, Anand P. Sodium channel Na v 1.7 immunoreactivity in painful human dental pulp and burning mouth syndrome. BMC Neurosci 2010; 11: 71.
    • (2010) BMC Neurosci , vol.11 , pp. 71
    • Beneng, K.1    Renton, T.2    Yilmaz, Z.3    Yiangou, Y.4    Anand, P.5
  • 42
    • 0020600187 scopus 로고
    • Axoplasmic transport block reduces ectopic impulse generation in injured peripheral nerves
    • Devor M, Govrin-Lippmann R. Axoplasmic transport block reduces ectopic impulse generation in injured peripheral nerves. Pain 1983; 16: 73-85.
    • (1983) Pain , vol.16 , pp. 73-85
    • Devor, M.1    Govrin-Lippmann, R.2
  • 43
    • 0016234844 scopus 로고
    • Ongoing activity in peripheral nerves: the physiology and pharmacology of impulses originating from a neuroma
    • Wall PD, Gutnick M. Ongoing activity in peripheral nerves: the physiology and pharmacology of impulses originating from a neuroma. Exp Neurol 1974; 43: 580-593.
    • (1974) Exp Neurol , vol.43 , pp. 580-593
    • Wall, P.D.1    Gutnick, M.2
  • 44
    • 0023696988 scopus 로고
    • Carbamazepine inhibits spontaneous activity in experimental neuromas
    • Burchiel KJ. Carbamazepine inhibits spontaneous activity in experimental neuromas. Exp Neurol 1988; 102: 249-253.
    • (1988) Exp Neurol , vol.102 , pp. 249-253
    • Burchiel, K.J.1
  • 45
    • 0026565417 scopus 로고
    • Systemic lidocaine silences ectopic neuroma and DRG discharge without blocking nerve conduction
    • Devor M, Wall PD, Catalan N. Systemic lidocaine silences ectopic neuroma and DRG discharge without blocking nerve conduction. Pain 1992; 48: 261-268.
    • (1992) Pain , vol.48 , pp. 261-268
    • Devor, M.1    Wall, P.D.2    Catalan, N.3
  • 46
    • 0028068798 scopus 로고
    • Hyperexcitability at sites of nerve injury depends on voltage-sensitive Na+ channels
    • Matzner O, Devor M. Hyperexcitability at sites of nerve injury depends on voltage-sensitive Na+ channels. J Neurophysiol 1994; 72: 349-359.
    • (1994) J Neurophysiol , vol.72 , pp. 349-359
    • Matzner, O.1    Devor, M.2
  • 47
    • 36148978879 scopus 로고    scopus 로고
    • Voltage-gated sodium channel blockers for the treatment of neuropathic pain
    • Cummins TR, Rush AM. Voltage-gated sodium channel blockers for the treatment of neuropathic pain. Expert Rev Neurother 2007; 7: 1597-1612.
    • (2007) Expert Rev Neurother , vol.7 , pp. 1597-1612
    • Cummins, T.R.1    Rush, A.M.2
  • 48
    • 66449112479 scopus 로고    scopus 로고
    • Voltage-gated sodium channel blockers for the treatment of chronic pain
    • Matulenko MA, Scanio MJ, Kort ME. Voltage-gated sodium channel blockers for the treatment of chronic pain. Curr Top Med Chem 2009; 9: 362-376.
    • (2009) Curr Top Med Chem , vol.9 , pp. 362-376
    • Matulenko, M.A.1    Scanio, M.J.2    Kort, M.E.3
  • 49
    • 33751014049 scopus 로고    scopus 로고
    • Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice
    • Nassar MA, Baker MD, Levato A, Ingram R, Mallucci G, McMahon SB, et al. Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice. Mol Pain 2006; 2: 33.
    • (2006) Mol Pain , vol.2 , pp. 33
    • Nassar, M.A.1    Baker, M.D.2    Levato, A.3    Ingram, R.4    Mallucci, G.5    McMahon, S.B.6
  • 50
    • 33845187874 scopus 로고    scopus 로고
    • Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8
    • Nassar MA, Levato A, Stirling LC, Wood JN. Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8. Mol Pain 2005; 1: 24.
    • (2005) Mol Pain , vol.1 , pp. 24
    • Nassar, M.A.1    Levato, A.2    Stirling, L.C.3    Wood, J.N.4
  • 51
    • 0035829033 scopus 로고    scopus 로고
    • A role for the TTX-resistant sodium channel Nav 1.8 in NGF-induced hyperalgesia, but not neuropathic pain
    • Kerr BJ, Souslova V, McMahon SB, Wood JN. A role for the TTX-resistant sodium channel Nav 1.8 in NGF-induced hyperalgesia, but not neuropathic pain. Neuroreport 2001; 12: 3077-3080.
    • (2001) Neuroreport , vol.12 , pp. 3077-3080
    • Kerr, B.J.1    Souslova, V.2    McMahon, S.B.3    Wood, J.N.4
  • 52
    • 2442651551 scopus 로고    scopus 로고
    • Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury
    • Hains BC, Saab CY, Klein JP, Craner MJ, Waxman SG. Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury. J Neurosci 2004; 24: 4832-4839.
    • (2004) J Neurosci , vol.24 , pp. 4832-4839
    • Hains, B.C.1    Saab, C.Y.2    Klein, J.P.3    Craner, M.J.4    Waxman, S.G.5
  • 53
    • 28844448678 scopus 로고    scopus 로고
    • Relationship between sodium channel NaV1.3 expression and neuropathic pain behavior in rats
    • Lindia JA, Kohler MG, Martin WJ, Abbadie C. Relationship between sodium channel NaV1.3 expression and neuropathic pain behavior in rats. Pain 2005; 117: 145-153.
    • (2005) Pain , vol.117 , pp. 145-153
    • Lindia, J.A.1    Kohler, M.G.2    Martin, W.J.3    Abbadie, C.4
  • 54
    • 0036145275 scopus 로고    scopus 로고
    • Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8
    • Lai J, Gold MS, Kim CS, Bian D, Ossipov MH, Hunter JC, et al. Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8. Pain 2002; 95: 143-152.
    • (2002) Pain , vol.95 , pp. 143-152
    • Lai, J.1    Gold, M.S.2    Kim, C.S.3    Bian, D.4    Ossipov, M.H.5    Hunter, J.C.6
  • 55
    • 34247373879 scopus 로고    scopus 로고
    • Small interfering RNA-mediated selective knockdown of Na(V)1.8 tetrodotoxin-resistant sodium channel reverses mechanical allodynia in neuropathic rats
    • Dong XW, Goregoaker S, Engler H, Zhou X, Mark L, Crona J, et al. Small interfering RNA-mediated selective knockdown of Na(V)1.8 tetrodotoxin-resistant sodium channel reverses mechanical allodynia in neuropathic rats. Neuroscience 2007; 146: 812-821.
    • (2007) Neuroscience , vol.146 , pp. 812-821
    • Dong, X.W.1    Goregoaker, S.2    Engler, H.3    Zhou, X.4    Mark, L.5    Crona, J.6
  • 56
    • 0001059602 scopus 로고    scopus 로고
    • A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain. [Review] [41 refs]
    • Porreca F, Lai J, Bian D, Wegert S, Ossipov MH, Eglen RM, et al. A comparison of the potential role of the tetrodotoxin-insensitive sodium channels, PN3/SNS and NaN/SNS2, in rat models of chronic pain. [Review] [41 refs]. Proc Natl Acad Sci U S A 1999; 96: 7640-7644.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 7640-7644
    • Porreca, F.1    Lai, J.2    Bian, D.3    Wegert, S.4    Ossipov, M.H.5    Eglen, R.M.6
  • 57
    • 34347213786 scopus 로고    scopus 로고
    • A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat
    • Jarvis MF, Honore P, Shieh CC, Chapman M, Joshi S, Zhang XF, et al. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Proc Natl Acad Sci U S A 2007; 104: 8520-8525.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 8520-8525
    • Jarvis, M.F.1    Honore, P.2    Shieh, C.C.3    Chapman, M.4    Joshi, S.5    Zhang, X.F.6
  • 59
    • 70149105324 scopus 로고    scopus 로고
    • A peripherally acting Na(v)1.7 sodium channel blocker reverses hyperalgesia and allodynia on rat models of inflammatory and neuropathic pain
    • McGowan E, Hoyt SB, Li X, Lyons KA, Abbadie C. A peripherally acting Na(v)1.7 sodium channel blocker reverses hyperalgesia and allodynia on rat models of inflammatory and neuropathic pain. Anesth Analg 2009; 109: 951-958.
    • (2009) Anesth Analg , vol.109 , pp. 951-958
    • McGowan, E.1    Hoyt, S.B.2    Li, X.3    Lyons, K.A.4    Abbadie, C.5
  • 60
    • 77954144829 scopus 로고    scopus 로고
    • A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats
    • Zhang XF, Shieh CC, Chapman ML, Matulenko MA, Hakeem AH, Atkinson RN, et al. A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats. Neuropharmacology 2010; 59: 201-207.
    • (2010) Neuropharmacology , vol.59 , pp. 201-207
    • Zhang, X.F.1    Shieh, C.C.2    Chapman, M.L.3    Matulenko, M.A.4    Hakeem, A.H.5    Atkinson, R.N.6
  • 61
    • 78449264276 scopus 로고    scopus 로고
    • Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Na(v)1.8 sodium channel with efficacy in a model of neuropathic pain
    • Scanio MJ, Shi L, Drizin I, Gregg RJ, Atkinson RN, Thomas JB, et al. Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Na(v)1.8 sodium channel with efficacy in a model of neuropathic pain. Bioorg Med Chem 2010; 18: 7816-7825.
    • (2010) Bioorg Med Chem , vol.18 , pp. 7816-7825
    • Scanio, M.J.1    Shi, L.2    Drizin, I.3    Gregg, R.J.4    Atkinson, R.N.5    Thomas, J.B.6
  • 63
    • 0035809303 scopus 로고    scopus 로고
    • Sodium channel beta1 and beta2 subunits parallel SNS/PN3 alpha-subunit changes in injured human sensory neurons
    • Coward K, Jowett A, Plumpton C, Powell A, Birch R, Tate S, et al. Sodium channel beta1 and beta2 subunits parallel SNS/PN3 alpha-subunit changes in injured human sensory neurons. Neuroreport 2001; 12: 483-488.
    • (2001) Neuroreport , vol.12 , pp. 483-488
    • Coward, K.1    Jowett, A.2    Plumpton, C.3    Powell, A.4    Birch, R.5    Tate, S.6
  • 66
    • 58149232445 scopus 로고    scopus 로고
    • Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas
    • Black JA, Nikolajsen L, Kroner K, Jensen TS, Waxman SG. Multiple sodium channel isoforms and mitogen-activated protein kinases are present in painful human neuromas. Ann Neurol 2008; 64: 644-653.
    • (2008) Ann Neurol , vol.64 , pp. 644-653
    • Black, J.A.1    Nikolajsen, L.2    Kroner, K.3    Jensen, T.S.4    Waxman, S.G.5
  • 67
    • 33947124182 scopus 로고    scopus 로고
    • Na(v)1.7 sodium channel expression in human lingual nerve neuromas
    • Bird EV, Robinson PP, Boissonade FM. Na(v)1.7 sodium channel expression in human lingual nerve neuromas. Arch Oral Biol 2007; 52: 494-502.
    • (2007) Arch Oral Biol , vol.52 , pp. 494-502
    • Bird, E.V.1    Robinson, P.P.2    Boissonade, F.M.3
  • 68
  • 70
    • 34547830207 scopus 로고    scopus 로고
    • Sodium channel Nav1.6 accumulates at the site of infraorbital nerve injury
    • Henry MA, Freking AR, Johnson LR, Levinson SR. Sodium channel Nav1.6 accumulates at the site of infraorbital nerve injury. BMC Neurosci 2007; 8: 56.
    • (2007) BMC Neurosci , vol.8 , pp. 56
    • Henry, M.A.1    Freking, A.R.2    Johnson, L.R.3    Levinson, S.R.4
  • 71
    • 0027398432 scopus 로고
    • Molecular dissection of the myelinated axon
    • Waxman SG, Ritchie JM. Molecular dissection of the myelinated axon. Ann Neurol 1993; 33: 121-136.
    • (1993) Ann Neurol , vol.33 , pp. 121-136
    • Waxman, S.G.1    Ritchie, J.M.2
  • 72
    • 0037382254 scopus 로고    scopus 로고
    • Electrical excitability of the soma of sensory neurons is required for spike invasion of the soma, but not for through-conduction
    • Amir R, Devor M. Electrical excitability of the soma of sensory neurons is required for spike invasion of the soma, but not for through-conduction. Biophys J 2003; 84: 2181-2191.
    • (2003) Biophys J , vol.84 , pp. 2181-2191
    • Amir, R.1    Devor, M.2
  • 73
  • 74
    • 0033198213 scopus 로고    scopus 로고
    • Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS
    • Rasband MN, Peles E, Trimmer JS, Levinson SR, Lux SE, Shrager P. Dependence of nodal sodium channel clustering on paranodal axoglial contact in the developing CNS. J Neurosci 1999; 19: 7516-7528.
    • (1999) J Neurosci , vol.19 , pp. 7516-7528
    • Rasband, M.N.1    Peles, E.2    Trimmer, J.S.3    Levinson, S.R.4    Lux, S.E.5    Shrager, P.6
  • 75
    • 0032145502 scopus 로고    scopus 로고
    • The effect of the mouse mutation claw paw on myelination and nodal frequency in sciatic nerves
    • Koszowski AG, Owens GC, Levinson SR. The effect of the mouse mutation claw paw on myelination and nodal frequency in sciatic nerves. J Neurosci 1998; 18: 5859-5868.
    • (1998) J Neurosci , vol.18 , pp. 5859-5868
    • Koszowski, A.G.1    Owens, G.C.2    Levinson, S.R.3
  • 76
    • 22544453872 scopus 로고    scopus 로고
    • Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier
    • Eshed Y, Feinberg K, Poliak S, Sabanay H, Sarig-Nadir O, Spiegel I, et al. Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier. Neuron 2005; 47: 215-229.
    • (2005) Neuron , vol.47 , pp. 215-229
    • Eshed, Y.1    Feinberg, K.2    Poliak, S.3    Sabanay, H.4    Sarig-Nadir, O.5    Spiegel, I.6
  • 77
    • 61549129037 scopus 로고    scopus 로고
    • Molecular domains of myelinated axons in the peripheral nervous system
    • Salzer JL, Brophy PJ, Peles E. Molecular domains of myelinated axons in the peripheral nervous system. Glia 2008; 56: 1532-1540.
    • (2008) Glia , vol.56 , pp. 1532-1540
    • Salzer, J.L.1    Brophy, P.J.2    Peles, E.3
  • 78
    • 33746930622 scopus 로고    scopus 로고
    • Intrinsic and extrinsic determinants of ion channel localization in neurons
    • Hedstrom KL, Rasband MN. Intrinsic and extrinsic determinants of ion channel localization in neurons. J Neurochem 2006; 98: 1345-1352.
    • (2006) J Neurochem , vol.98 , pp. 1345-1352
    • Hedstrom, K.L.1    Rasband, M.N.2
  • 79
    • 0031768298 scopus 로고    scopus 로고
    • Pain in central and peripheral demyelinating disorders
    • Moulin DE. Pain in central and peripheral demyelinating disorders. Neurol Clin 1998; 16: 889-898.
    • (1998) Neurol Clin , vol.16 , pp. 889-898
    • Moulin, D.E.1
  • 80
    • 0037996903 scopus 로고    scopus 로고
    • Focal lysolecithin-induced demyelination of peripheral afferents results in neuropathic pain behavior that is attenuated by cannabinoids
    • Wallace VC, Cottrell DF, Brophy PJ, Fleetwood-Walker SM. Focal lysolecithin-induced demyelination of peripheral afferents results in neuropathic pain behavior that is attenuated by cannabinoids. J Neurosci 2003; 23: 3221-3233.
    • (2003) J Neurosci , vol.23 , pp. 3221-3233
    • Wallace, V.C.1    Cottrell, D.F.2    Brophy, P.J.3    Fleetwood-Walker, S.M.4
  • 81
    • 0025782767 scopus 로고
    • Increased numbers of sodium channels form along demyelinated axons
    • England JD, Gamboni F, Levinson SR. Increased numbers of sodium channels form along demyelinated axons. Brain Res 1991; 548: 334-337.
    • (1991) Brain Res , vol.548 , pp. 334-337
    • England, J.D.1    Gamboni, F.2    Levinson, S.R.3
  • 83
    • 0030904472 scopus 로고    scopus 로고
    • Clustering of voltage-sensitive sodium channels on axons is independent of direct Schwann cell contact in the dystrophic mouse
    • Deerinck TJ, Levinson SR, Bennett GV, Ellisman MH. Clustering of voltage-sensitive sodium channels on axons is independent of direct Schwann cell contact in the dystrophic mouse. J Neurosci 1997; 17: 5080-5088.
    • (1997) J Neurosci , vol.17 , pp. 5080-5088
    • Deerinck, T.J.1    Levinson, S.R.2    Bennett, G.V.3    Ellisman, M.H.4
  • 84
    • 77955416936 scopus 로고    scopus 로고
    • Pulpitis increases the proportion of atypical nodes of Ranvier in human dental pulp axons without a change in Nav1.6 sodium channel expression
    • Luo S, Perry GM, Levinson SR, Henry MA. Pulpitis increases the proportion of atypical nodes of Ranvier in human dental pulp axons without a change in Nav1.6 sodium channel expression. Neuroscience 2010; 169: 1881-1887.
    • (2010) Neuroscience , vol.169 , pp. 1881-1887
    • Luo, S.1    Perry, G.M.2    Levinson, S.R.3    Henry, M.A.4
  • 85
    • 33746804654 scopus 로고    scopus 로고
    • Increased sodium channel immunofluorescence at myelinated and demyelinated sites following an inflammatory and partial axotomy lesion of the rat infraorbital nerve
    • Henry MA, Freking AR, Johnson LR, Levinson SR. Increased sodium channel immunofluorescence at myelinated and demyelinated sites following an inflammatory and partial axotomy lesion of the rat infraorbital nerve. Pain 2006; 124: 222-233.
    • (2006) Pain , vol.124 , pp. 222-233
    • Henry, M.A.1    Freking, A.R.2    Johnson, L.R.3    Levinson, S.R.4
  • 86
    • 43749121619 scopus 로고    scopus 로고
    • Nav1.7 expression is increased in painful human dental pulp
    • Luo S, Perry G, Levinson SR, Henry M. Nav1.7 expression is increased in painful human dental pulp. Molecular Pain 2008; 4: 16.
    • (2008) Molecular Pain , vol.4 , pp. 16
    • Luo, S.1    Perry, G.2    Levinson, S.R.3    Henry, M.4
  • 87
    • 66449110564 scopus 로고    scopus 로고
    • Recent advances in the medicinal chemistry of sodium channel blockers and their therapeutic potential
    • Zuliani V, Patel MK, Fantini M, Rivara M. Recent advances in the medicinal chemistry of sodium channel blockers and their therapeutic potential. Curr Top Med Chem 2009; 9: 396-415.
    • (2009) Curr Top Med Chem , vol.9 , pp. 396-415
    • Zuliani, V.1    Patel, M.K.2    Fantini, M.3    Rivara, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.