메뉴 건너뛰기




Volumn 8, Issue 4, 2012, Pages 548-555

β-Galactosylated alkyl-oligoamine derivatives of polyethylenimine enhanced pDNA delivery into hepatic cells with reduced toxicity

Author keywords

Cytotoxicity; Galactose; Gene delivery; Nanoparticle; Polyethylenimine; Targeting

Indexed keywords

ALKYL CHAIN LENGTHS; AMIDE LINKAGES; ASIALOGLYCOPROTEIN RECEPTORS; CARCINOMA CELLS; DIETHYLENTRIAMINE; GALACTOSE; GENE CARRIER; GENE DELIVERY; HEPATIC CELLS; HUMAN LIVER; PLASMID DNA; POLYETHYLENIMINES; POLYPLEXES; PRIMARY AMINES; REDUCED TOXICITY; REDUCTIVE AMINATION; REPORTER GENE; SPERMIDINE; TARGETING; TRANSFECTION EFFICIENCY; WEIGHT RATIOS;

EID: 84863961600     PISSN: 15734137     EISSN: 18756786     Source Type: Journal    
DOI: 10.2174/157341312801784339     Document Type: Article
Times cited : (29)

References (41)
  • 1
    • 8544230612 scopus 로고    scopus 로고
    • Cationic compounds used in lipoplexes and polyplexes for gene delivery
    • Zhang, S.; Xu, Y.; Wang, B.; Qiao, W.; Liu, D.; Li, Z. Cationic compounds used in lipoplexes and polyplexes for gene delivery. J. Control. Release, 2004, 100, 165-180.
    • (2004) J. Control. Release , vol.100 , pp. 165-180
    • Zhang, S.1    Xu, Y.2    Wang, B.3    Qiao, W.4    Liu, D.5    Li, Z.6
  • 2
    • 0029799791 scopus 로고    scopus 로고
    • A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: Polyethylenimine
    • Abdallah, B.; Hassan, A.; Benoist, C.; Goula, D.; Behr, J.P.; Demeneix, B. A. A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine. Hum. Gene Ther., 1996, 7, 1947-1954.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1947-1954
    • Abdallah, B.1    Hassan, A.2    Benoist, C.3    Goula, D.4    Behr, J.P.5    Demeneix, B.A.6
  • 4
    • 78650476432 scopus 로고    scopus 로고
    • The proton sponge: A trick to enter cells the viruses did not exploit
    • Behr, J. P. The proton sponge: a trick to enter cells the viruses did not exploit. CHIMIA, 1997, 1, 34-36.
    • (1997) CHIMIA , vol.1 , pp. 34-36
    • Behr, J.P.1
  • 5
    • 65749120721 scopus 로고    scopus 로고
    • Nanocarriers for gene deliverypolymer structure, targeting ligands and controlled-release devices
    • Elfinger, M.; Uzgun, S.; Rudolph, C., Nanocarriers for gene deliverypolymer structure, targeting ligands and controlled-release devices. Curr. Nanosci., 2008, 4, 322-353.
    • (2008) Curr. Nanosci. , vol.4 , pp. 322-353
    • Elfinger, M.1    Uzgun, S.2    Rudolph, C.3
  • 6
    • 79551662333 scopus 로고    scopus 로고
    • Non-viral gene delivery and therapeutics targeting to brain
    • Liu, Y.; Huang, R.; Jiang, C. Non-viral gene delivery and therapeutics targeting to brain. Curr. Nanosci., 2011, 7, 55-70.
    • (2011) Curr. Nanosci. , vol.7 , pp. 55-70
    • Liu, Y.1    Huang, R.2    Jiang, C.3
  • 7
    • 0028501007 scopus 로고
    • Gene transfer with synthetic cationic amphiphiles: Prospects for gene therapy
    • Behr, J. P. Gene transfer with synthetic cationic amphiphiles: prospects for gene therapy. Bioconjug. Chem., 1994, 5, 382-389.
    • (1994) Bioconjug. Chem. , vol.5 , pp. 382-389
    • Behr, J.P.1
  • 8
    • 0029981092 scopus 로고    scopus 로고
    • Evidence for the role of proteoglycans in cation-mediated gene transfer
    • Mislick, K.A.; Baldeschwieler, J.D., Evidence for the role of proteoglycans in cation-mediated gene transfer. Proc. Natl. Acad. Sci. USA, 1996, 93, 12349-12354.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 12349-12354
    • Mislick, K.A.1    Baldeschwieler, J.D.2
  • 9
    • 0033609001 scopus 로고    scopus 로고
    • Tracking the intracellular path of poly (ethylenimine)/DNA complexes for gene delivery
    • Godbey, W.; Wu, K.K.; Mikos, A.G. Tracking the intracellular path of poly (ethylenimine)/DNA complexes for gene delivery. Proc. Natl. Acad. Sci. USA, 1999, 96, 5177-5181.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5177-5181
    • Godbey, W.1    Wu, K.K.2    Mikos, A.G.3
  • 11
    • 0027297678 scopus 로고
    • Receptor-mediated transport of DNA into eukaryotic cells
    • Cotten, M.; Wagner, E.; Birnstiel, M.L. Receptor-mediated transport of DNA into eukaryotic cells. Methods Enzymol., 1993, 217, 618-644.
    • (1993) Methods Enzymol. , vol.217 , pp. 618-644
    • Cotten, M.1    Wagner, E.2    Birnstiel, M.L.3
  • 12
    • 0029688659 scopus 로고    scopus 로고
    • Epidermal growth factor mediated DNA delivery into lung cancer cells via the epidermal growth factor receptor
    • Cristiano, R.J.; Roth, J.A. Epidermal growth factor mediated DNA delivery into lung cancer cells via the epidermal growth factor receptor. Cancer Gene Ther., 1996, 3, 4-10.
    • (1996) Cancer Gene Ther. , vol.3 , pp. 4-10
    • Cristiano, R.J.1    Roth, J.A.2
  • 13
    • 0028416238 scopus 로고
    • Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis
    • Wagner, E.; Curiel, D.; Cotten, M. Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis. Adv. Drug Deliv. Rev., 1994, 14 (1), 113-135.
    • (1994) Adv. Drug Deliv. Rev. , vol.14 , Issue.1 , pp. 113-135
    • Wagner, E.1    Curiel, D.2    Cotten, M.3
  • 14
    • 0037136420 scopus 로고    scopus 로고
    • Glycans as endocytosis signals: The cases of the asialoglycoprotein and hyaluronan/chondroitin sulfate receptors
    • Weigel, P.H.; Yik, J. H.N. Glycans as endocytosis signals: the cases of the asialoglycoprotein and hyaluronan/chondroitin sulfate receptors. Biochim. Biophys. Acta. 2002, 1572, 341-363.
    • (2002) Biochim. Biophys. Acta. , vol.1572 , pp. 341-363
    • Weigel, P.H.1    Yik, J.H.N.2
  • 15
    • 0031281282 scopus 로고    scopus 로고
    • In vitro gene delivery to hepatocytes with galactosylated polyethylenimine
    • Zanta, M.A.; Boussif, O.; Adib, A.; Behr, J.P. In vitro gene delivery to hepatocytes with galactosylated polyethylenimine. Bioconjug. Chem., 1997, 8, 839-844.
    • (1997) Bioconjug. Chem. , vol.8 , pp. 839-844
    • Zanta, M.A.1    Boussif, O.2    Adib, A.3    Behr, J.P.4
  • 16
    • 0037436017 scopus 로고    scopus 로고
    • Galactose-PEI-DNA complexes for targeted gene delivery: Degree of substitution affects complex size and transfection efficiency
    • Kunath, K.; von Harpe, A.; Fischer, D.; Kissel, T. Galactose-PEI-DNA complexes for targeted gene delivery: degree of substitution affects complex size and transfection efficiency. J. Control. Release, 2003, 88, 159-172.
    • (2003) J. Control. Release , vol.88 , pp. 159-172
    • Kunath, K.1    von Harpe, A.2    Fischer, D.3    Kissel, T.4
  • 17
    • 78149424866 scopus 로고    scopus 로고
    • Galactosyl conjugated N-succinyl-chitosan-graft-polyethylenimine for targeting gene transfer
    • Lu, B.; Wu, D.Q.; Zheng, H.; Quan, C.Y.; Zhang, X.Z.; Zhuo, R.X. Galactosyl conjugated N-succinyl-chitosan-graft-polyethylenimine for targeting gene transfer. Mol. Biosyst., 2010, 6, 2529-2538.
    • (2010) Mol. Biosyst. , vol.6 , pp. 2529-2538
    • Lu, B.1    Wu, D.Q.2    Zheng, H.3    Quan, C.Y.4    Zhang, X.Z.5    Zhuo, R.X.6
  • 18
    • 77950803130 scopus 로고    scopus 로고
    • Galactosylated poly (2-(2-aminoethyoxy) ethoxy) phosphazene/DNA complex nanoparticles: In vitro and in vivo evaluation for gene delivery
    • Yang, Y.; Zhang, Z.; Chen, L.; Gu, W.; Li, Y. Galactosylated poly (2-(2-aminoethyoxy) ethoxy) phosphazene/DNA complex nanoparticles: in vitro and in vivo evaluation for gene delivery. Biomacromolecules, 2010, 11, 927-933.
    • (2010) Biomacromolecules , vol.11 , pp. 927-933
    • Yang, Y.1    Zhang, Z.2    Chen, L.3    Gu, W.4    Li, Y.5
  • 19
    • 79955581945 scopus 로고    scopus 로고
    • Spermine grafted galactosylated chitosan for improved nanoparticle mediated gene delivery
    • Alex, S.M.; Rekha, M.; Sharma, C. P. Spermine grafted galactosylated chitosan for improved nanoparticle mediated gene delivery. Int. J. Pharm., 2011, 410, 125-137.
    • (2011) Int. J. Pharm. , vol.410 , pp. 125-137
    • Alex, S.M.1    Rekha, M.2    Sharma, C.P.3
  • 20
    • 80051753621 scopus 로고    scopus 로고
    • Galactosylated N-2-hydroxypropyl methacrylamide-b-N-3-guanidinopropyl methacrylamide block copolymers as hepatocyte-targeting gene carriers
    • Qin, Z.; Liu, W.; Li, L.; Guo, L.; Yao, C.; Li, X. Galactosylated N-2-hydroxypropyl methacrylamide-b-N-3-guanidinopropyl methacrylamide block copolymers as hepatocyte-targeting gene carriers. Bioconjug. Chem., 2011, 22, 1503-1512.
    • (2011) Bioconjug. Chem. , vol.22 , pp. 1503-1512
    • Qin, Z.1    Liu, W.2    Li, L.3    Guo, L.4    Yao, C.5    Li, X.6
  • 21
    • 79960002359 scopus 로고    scopus 로고
    • Hepatocyte-targeted psiRNA delivery mediated by galactosylated poly (ethylene glycol)-graftpolyethylenimine in vitro
    • Nie, C.; Liu, C.; Chen, G.; Dai, J.; Li, H.; Shuai, X. Hepatocyte-targeted psiRNA delivery mediated by galactosylated poly (ethylene glycol)-graftpolyethylenimine in vitro. J. Biomater. Appl., 2011, 26, 255-275.
    • (2011) J. Biomater. Appl. , vol.26 , pp. 255-275
    • Nie, C.1    Liu, C.2    Chen, G.3    Dai, J.4    Li, H.5    Shuai, X.6
  • 22
    • 0001451822 scopus 로고    scopus 로고
    • Characterization of a targeted gene carrier, lactose-polyethylene glycol-grafted poly-L-lysine, and its complex with plasmid DNA
    • Choi, Y. H.; Liu, F.; Choi, J.S.; Kim, S. W.; Park, J.S. Characterization of a targeted gene carrier, lactose-polyethylene glycol-grafted poly-L-lysine, and its complex with plasmid DNA. Hum. Gene Ther., 1999, 10, 2657-2665.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 2657-2665
    • Choi, Y.H.1    Liu, F.2    Choi, J.S.3    Kim, S.W.4    Park, J.S.5
  • 23
    • 0001121655 scopus 로고    scopus 로고
    • Lactose-poly (ethylene glycol)-grafted poly-L-lysine as hepatoma cell-targeted gene carrier
    • Choi, Y. H.; Liu, F.; Park, J.S.; Kim, S.W. Lactose-poly (ethylene glycol)-grafted poly-L-lysine as hepatoma cell-targeted gene carrier. Bioconjug. Chem., 1998, 9, 708-718.
    • (1998) Bioconjug. Chem. , vol.9 , pp. 708-718
    • Choi, Y.H.1    Liu, F.2    Park, J.S.3    Kim, S.W.4
  • 24
    • 27744585027 scopus 로고    scopus 로고
    • Asialoglycoprotein receptor targeted gene delivery using galactosylated polyethylenimine-graft-poly (ethylene glycol): In vitro and in vivo studies
    • Kim, E.M.; Jeong, H.J.; Park, I.K.; Cho, C.S.; Moon, H. B.; Yu, D.Y.; Bom, H.S.; Sohn, M. H.; Oh, I.J. Asialoglycoprotein receptor targeted gene delivery using galactosylated polyethylenimine-graft-poly (ethylene glycol): In vitro and in vivo studies. J. Control. Release, 2005, 108, 557-567.
    • (2005) J. Control. Release , vol.108 , pp. 557-567
    • Kim, E.M.1    Jeong, H.J.2    Park, I.K.3    Cho, C.S.4    Moon, H.B.5    Yu, D.Y.6    Bom, H.S.7    Sohn, M.H.8    Oh, I.J.9
  • 25
    • 0027133660 scopus 로고
    • Hepatic gene therapy: Efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex
    • Cristiano, R.J.; Smith, L.C.; Kay, M.A.; Brinkley, B.; Woo, S. Hepatic gene therapy: efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex. Proc. Natl. Acad. Sci. USA, 1993, 90, 11548-11552.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11548-11552
    • Cristiano, R.J.1    Smith, L.C.2    Kay, M.A.3    Brinkley, B.4    Woo, S.5
  • 26
    • 4043071644 scopus 로고
    • Cyanohydridoborate anion as a selective reducing agent
    • Borch, R.F.; Bernstein, M.D.; Durst, H.D. Cyanohydridoborate anion as a selective reducing agent. J. Am. Chem. Soc., 1971, 93, 2897-2904.
    • (1971) J. Am. Chem. Soc. , vol.93 , pp. 2897-2904
    • Borch, R.F.1    Bernstein, M.D.2    Durst, H.D.3
  • 27
    • 0141838188 scopus 로고    scopus 로고
    • Improved stability of polycationic vector by dextran-grafted branched polyethylenimine
    • Tseng, W.C.; Jong, C.M. Improved stability of polycationic vector by dextran-grafted branched polyethylenimine. Biomacromolecules, 2003, 4, 1277-1284.
    • (2003) Biomacromolecules , vol.4 , pp. 1277-1284
    • Tseng, W.C.1    Jong, C.M.2
  • 28
    • 0016636179 scopus 로고
    • An improved 2, 4, 6-trinitrobenzenesulfonic acid method for the determination of amines
    • Snyder, S.L.; Sobocinski, P.Z. An improved 2, 4, 6-trinitrobenzenesulfonic acid method for the determination of amines. Anal. Biochem., 1975, 64, 284-288.
    • (1975) Anal. Biochem. , vol.64 , pp. 284-288
    • Snyder, S.L.1    Sobocinski, P.Z.2
  • 29
    • 0024210793 scopus 로고
    • Colorimetric determination of neutral sugars by a resorcinol sulfuric acid micromethod
    • Monsigny, M.; Petit, C.; Roche, A.C. Colorimetric determination of neutral sugars by a resorcinol sulfuric acid micromethod. Anal. Biochem., 1988, 175, 525-530.
    • (1988) Anal. Biochem. , vol.175 , pp. 525-530
    • Monsigny, M.1    Petit, C.2    Roche, A.C.3
  • 30
    • 33845221800 scopus 로고    scopus 로고
    • Characterizing the structure/function parameter space of hydrocarbonconjugated branched polyethylenimine for DNA delivery in vitro
    • Doody, A.M.; Korley, J.N.; Dang, K.P.; Zawaneh, P.N.; Putnam, D. Characterizing the structure/function parameter space of hydrocarbonconjugated branched polyethylenimine for DNA delivery in vitro. J. Control. Release, 2006, 116, 227-237.
    • (2006) J. Control. Release , vol.116 , pp. 227-237
    • Doody, A.M.1    Korley, J.N.2    Dang, K.P.3    Zawaneh, P.N.4    Putnam, D.5
  • 31
    • 33748374275 scopus 로고    scopus 로고
    • Acetylation of polyethylenimine enhances gene delivery via weakened polymer/DNA interactions
    • Gabrielson, N.P.; Daniel, W. Acetylation of polyethylenimine enhances gene delivery via weakened polymer/DNA interactions. Biomacromolecules, 2006, 7, 2427-2435.
    • (2006) Biomacromolecules , vol.7 , pp. 2427-2435
    • Gabrielson, N.P.1    Daniel, W.2
  • 32
    • 0037069319 scopus 로고    scopus 로고
    • Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells
    • Thomas, M.; Klibanov, A. M. Enhancing polyethylenimine's delivery of plasmid DNA into mammalian cells. Proc. Natl. Acad. Sci. USA, 2002, 99, 14640-14645.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 14640-14645
    • Thomas, M.1    Klibanov, A.M.2
  • 33
    • 1242292220 scopus 로고    scopus 로고
    • Partial acetylation of polyethylenimine enhances in vitro gene delivery
    • Forrest, M.L.; Meister, G.E.; Koerber, J.T.; Pack, D.W. Partial acetylation of polyethylenimine enhances in vitro gene delivery. Pharm. Res., 2004, 21, 365-371.
    • (2004) Pharm. Res. , vol.21 , pp. 365-371
    • Forrest, M.L.1    Meister, G.E.2    Koerber, J.T.3    Pack, D.W.4
  • 34
    • 34248569846 scopus 로고    scopus 로고
    • Influence of acyl chain length on transfection mediated by acylated PEI nanoparticles
    • Nimesh, S.; Aggarwal, A.; Kumar, P.; Singh, Y.; Gupta, K.; Chandra, R. Influence of acyl chain length on transfection mediated by acylated PEI nanoparticles. Int. J. Pharm., 2007, 337, 265-274.
    • (2007) Int. J. Pharm. , vol.337 , pp. 265-274
    • Nimesh, S.1    Aggarwal, A.2    Kumar, P.3    Singh, Y.4    Gupta, K.5    Chandra, R.6
  • 35
    • 72449157092 scopus 로고    scopus 로고
    • Alkylcarboxylate grafting to polyethylenimine: A simple approach to producing a DNA nanocarrier with low toxicity
    • Oskuee, R.K.; Dehshahri, A.; Shier, W.T.; Ramezani, M. Alkylcarboxylate grafting to polyethylenimine: a simple approach to producing a DNA nanocarrier with low toxicity. J. Gene Med., 2009, 11, 921-932.
    • (2009) J. Gene Med. , vol.11 , pp. 921-932
    • Oskuee, R.K.1    Dehshahri, A.2    Shier, W.T.3    Ramezani, M.4
  • 36
    • 0033122034 scopus 로고    scopus 로고
    • Transfection and physical properties of various saccharide, poly (ethylene glycol), and antibody derivatized polyethylenimines (PEI)
    • Erbacher, P.; Bettinger, T.; Belguise Valladier, P.; Zou, S.; Coll, J.L.; Behr, J.P.; Remy, J.S. Transfection and physical properties of various saccharide, poly (ethylene glycol), and antibody derivatized polyethylenimines (PEI). J. Gene Med., 1999, 1, 210-222.
    • (1999) J. Gene Med. , vol.1 , pp. 210-222
    • Erbacher, P.1    Bettinger, T.2    Belguise Valladier, P.3    Zou, S.4    Coll, J.L.5    Behr, J.P.6    Remy, J.S.7
  • 37
    • 19444372923 scopus 로고    scopus 로고
    • A two-stage poly (ethylenimine)-mediated cytotoxicity: Implications for gene transfer/therapy
    • Moghimi, S.M.; Symonds, P.; Murray, J.C.; Hunter, A.C.; Debska, G.; Szewczyk, A. A two-stage poly (ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy. Mol. Ther., 2005, 11, 990-995.
    • (2005) Mol. Ther. , vol.11 , pp. 990-995
    • Moghimi, S.M.1    Symonds, P.2    Murray, J.C.3    Hunter, A.C.4    Debska, G.5    Szewczyk, A.6
  • 38
    • 47749100430 scopus 로고    scopus 로고
    • Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity
    • Zintchenko, A.; Philipp, A.; Dehshahri, A.; Wagner, E. Simple modifications of branched PEI lead to highly efficient siRNA carriers with low toxicity. Bioconjug. Chem., 2008, 19, 1448-1455.
    • (2008) Bioconjug. Chem. , vol.19 , pp. 1448-1455
    • Zintchenko, A.1    Philipp, A.2    Dehshahri, A.3    Wagner, E.4
  • 39
    • 0037409735 scopus 로고    scopus 로고
    • Polyethylene glycol modified polyethylenimine for improved CNS gene transfer: Effects of PEGylation extent
    • Tang, G.; Zeng, J.; Gao, S.; Ma, Y.; Shi, L.; Li, Y.; Too, H.P.; Wang, S. Polyethylene glycol modified polyethylenimine for improved CNS gene transfer: effects of PEGylation extent. Biomaterials, 2003, 24, 2351-2362.
    • (2003) Biomaterials , vol.24 , pp. 2351-2362
    • Tang, G.1    Zeng, J.2    Gao, S.3    Ma, Y.4    Shi, L.5    Li, Y.6    Too, H.P.7    Wang, S.8
  • 40
    • 0034601856 scopus 로고    scopus 로고
    • Galactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrier
    • Park, Y.; Park, Y.; Shin, B.; Choi, E.; Park, Y.; Akaike, T.; Cho, C. Galactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrier. J. Control. Release, 2000, 69, 97-108.
    • (2000) J. Control. Release , vol.69 , pp. 97-108
    • Park, Y.1    Park, Y.2    Shin, B.3    Choi, E.4    Park, Y.5    Akaike, T.6    Cho, C.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.