Asialoglycoprotein receptor targeted gene delivery using galactosylated polyethylenimine-graft-poly(ethylene glycol): In vitro and in vivo studies

Journal of Controlled Release

Volumn 108, Issue 2-3, 2005, Pages 557-567

  Kim, Eun Mi ^a   Jeong, Hwan Jeong ^a,g   Park, In Kyu ^b   Cho, Chong Su ^b   Moon, Hyung Bae ^c   Yu, Dae Yeul ^d   Bom, Hee Seung ^e   Sohn, Myung Hee ^a   Oh, In Joon ^f  

^a Chonbuk National University Medical School   (South Korea)

^b Seoul National University   (South Korea)

^c Wonkwang University School of Medicine   (South Korea)

^d Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^e Chonnam National University Medical School   (South Korea)

^f Chonnam National University   (South Korea)

^g Jeonbuk National University Medical School and Hospital   (South Korea)

Author keywords

Asialoglycoprotein receptor; Hepatocellular carcinoma animal model; Polyethylenimine; Technetium 99m

Indexed keywords

BIOLOGICAL MEMBRANES; BIOMARKERS; CELLS; GENETIC ENGINEERING; NITROGEN COMPOUNDS; POLYETHYLENE GLYCOLS;

ASIALOGLYCOPROTEIN RECEPTORS; HEPATOCELLULAR CARCINOMA ANIMAL MODEL; POLYETHYLENIMINE; TECHNETIUM-99M;

GENES;

ASIALOGLYCOPROTEIN RECEPTOR; DNA; GALACTOSYLATED POLYETHYLENIMINE; GALACTOSYLATED POLYETHYLENIMINE GRAFT POLY(ETHYLENE GLYCOL); GREEN FLUORESCENT PROTEIN; MACROGOL; POLYETHYLENE DERIVATIVE; POLYETHYLENEIMINE DERIVATIVE; TECHNETIUM 99M; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CELL STRAIN HEPG2; CHEMICAL COMPOSITION; CONTROLLED STUDY; CYTOTOXICITY; FEASIBILITY STUDY; FEMALE; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HEART; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LIVER; LIVER CELL; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; REPORTER GENE; STAINING; TISSUE DISTRIBUTION; TRANSGENIC MOUSE; URINARY EXCRETION; ZETA POTENTIAL;

ANIMALS; ASIALOGLYCOPROTEIN RECEPTOR; CELL LINE, TUMOR; CELL SURVIVAL; DNA; DRUG DELIVERY SYSTEMS; ELECTROCHEMISTRY; GENE EXPRESSION REGULATION; GENE THERAPY; GENES, RAS; GREEN FLUORESCENT PROTEINS; HEPATOCYTES; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, TRANSGENIC; POLYETHYLENE GLYCOLS; RADIONUCLIDE IMAGING; TECHNETIUM; TETRAZOLIUM SALTS; THIAZOLES; TRANSFECTION;

EID: 27744585027     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.09.001     Document Type: Article

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