Hepatocyte-targeted psiRNA delivery mediated by galactosylated poly(Ethylene Glycol)-graft-polyethylenimine in vitro

Journal of Biomaterials Applications

Volumn 26, Issue 3, 2011, Pages 255-275

  Nie, Changfu ^a   Liu, Chuntao ^a   Chen, Guihua ^a   Dai, Jian ^a   Li, Hua ^a   Shuai, Xintao ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

galactose; gene silencing; hepatocyte targeting; nonviral vector; siRNA delivery

Indexed keywords

GALACTOSE; GENE SILENCING; HEPATOCYTES; NONVIRAL VECTORS; SIRNA DELIVERY;

CELL CULTURE; EFFICIENCY; ETHYLENE; GENE EXPRESSION; GENETIC ENGINEERING; GLYCOLS; GRAFTING (CHEMICAL); LIPOSOMES; POLYETHYLENE OXIDES; POLYMERASE CHAIN REACTION; ZETA POTENTIAL;

POLYETHYLENE GLYCOLS;

BIOMATERIAL; GALACTOSE POLY(ETHYLENE GLYCOL) POLYETHYLENIMINE; GALACTOSE-POLY(ETHYLENE GLYCOL)-POLYETHYLENIMINE; HLA ANTIGEN CLASS 1; HLA E ANTIGEN; HLA-E ANTIGEN; LIPID; LIPOFECTAMINE; MACROGOL DERIVATIVE; NANOMATERIAL; POLYETHYLENEIMINE; SMALL INTERFERING RNA;

ARTICLE; CELL STRAIN HEPG2; CELL SURVIVAL; CHEMISTRY; EVALUATION; GENE SILENCING; GENETIC TRANSFECTION; GENETICS; HUMAN; LIVER CELL; MATERIALS TESTING; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; NUCLEOTIDE SEQUENCE; PARTICLE SIZE; PLASMID; RNA STABILITY; SYNTHESIS; TRANSMISSION ELECTRON MICROSCOPY;

BASE SEQUENCE; BIOCOMPATIBLE MATERIALS; CELL SURVIVAL; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HEP G2 CELLS; HEPATOCYTES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; LIPIDS; MATERIALS TESTING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOSTRUCTURES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PARTICLE SIZE; PLASMIDS; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; RNA STABILITY; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 79960002359     PISSN: 08853282     EISSN: 15308022     Source Type: Journal    
DOI: 10.1177/0885328210364678     Document Type: Article

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