Mulberry leaf polyphenol extract induced apoptosis involving regulation of adenosine monophosphate-activated protein kinase/fatty acid synthase in a p53-negative hepatocellular carcinoma cell

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 27, 2012, Pages 6891-6898

  Yang, Tzi Peng ^a   Lee, Huei Jane ^a   Ou, Ting Tsz ^a   Chang, Ya Ju ^a   Wang, Chau Jong ^a,b  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

AMP activated protein kinase; apoptosis; fatty acid synthase; mulberry leaf polyphenol extract; p53 negative Hep3B cell

Indexed keywords

ACRIDINE ORANGE STAINING; AFTER-TREATMENT; AMP-ACTIVATED PROTEIN KINASE; AUTOPHAGY; BCL-2 FAMILY; CELL CYCLE; FATTY ACID SYNTHASE; HEPATOCELLULAR CARCINOMA CELL; INDUCED APOPTOSIS; MOLECULAR TARGETS; POLYPHENOL EXTRACT; POLYPHENOLS; PROTEIN EXPRESSIONS; PROTEIN KINASE; SYNTHASES; TRANSFECTED CELLS; TRANSIENT TRANSFECTION;

CELL DEATH; CELL PROLIFERATION; ENZYME ACTIVITY; PHENOLS; PLANTS (BOTANY);

MOLECULAR BIOLOGY;

FASN PROTEIN, HUMAN; FATTY ACID SYNTHASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PLANT EXTRACT; POLYPHENOL; PROTEIN P53;

APOPTOSIS; ARTICLE; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; GENETICS; HUMAN; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; MORUS; PATHOPHYSIOLOGY; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; FATTY ACID SYNTHASE, TYPE I; HUMANS; LIVER NEOPLASMS; MORUS; PLANT EXTRACTS; POLYPHENOLS; TUMOR SUPPRESSOR PROTEIN P53;

MORUS (ANGIOSPERM);

EID: 84863890852     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf302183x     Document Type: Article

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