Inhibitory effect of 2,4,2′,4′-tetrahydroxy-3-(3-methyl-2- butenyl)-chalcone on tyrosinase activity and melanin biosynthesis

Biological and Pharmaceutical Bulletin

Volumn 32, Issue 1, 2009, Pages 86-90

  Zhang, Xiaodong ^a   Hu, Xiao ^b   Hou, Aijun ^b   Wang, Heyao ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

2,4,2 ,4 tetrahydroxy 3 (3 methyl 2 butenyl) chalcone; Melanin; Melanin biosynthesis; Tyrosinase

Indexed keywords

2,4,2',4' TETRAHYDROXY 3 (3 METHYL 2 BUTENYL)CHALCONE; CATECHOL OXIDASE; CHALCONE DERIVATIVE; COSMETIC; KOJIC ACID; LEVODOPA; MELANIN; MONOPHENOL MONOOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL VIABILITY; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; GENE REPRESSION; IC 50; MELANOGENESIS; MELANOMA CELL; MOUSE; NONHUMAN; PLANT STEM; REAL TIME POLYMERASE CHAIN REACTION;

ALPHA-MSH; ANIMALS; ANTIOXIDANTS; CELL LINE, TUMOR; CELL SURVIVAL; CHALCONE; DOPAMINE AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, NEOPLASTIC; INHIBITORY CONCENTRATION 50; LEVODOPA; MELANINS; MELANOMA, EXPERIMENTAL; MICE; MONOPHENOL MONOOXYGENASE; PLANT EXTRACTS; PYRONES; RNA, MESSENGER;

EID: 59949085461     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.32.86     Document Type: Article

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