SiRNA targeting Notch-1 decreases glioma stem cell proliferation and tumor growth

Molecular Biology Reports

Volumn 39, Issue 3, 2012, Pages 2497-2503

  Wang, Jianpeng ^a,b   Wang, Chao ^a   Meng, Qinghai ^a   Li, Shifang ^a   Sun, Xiaopeng ^a   Bo, Yongli ^a   Yao, Weicheng ^a  

^a QINGDAO UNIVERSITY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Glioblastoma multiforme; Glioma stem cells; Notch 1; Polyethyleneimine; Small interfering RNA

Indexed keywords

NOTCH1 RECEPTOR; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER GENE THERAPY; CANCER INHIBITION; CANCER STEM CELL; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CELL PROLIFERATION; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GLIOBLASTOMA; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASTIC STEM CELLS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, NOTCH1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES; TRANSFECTION;

MUS MUSCULUS;

EID: 84863855324     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-011-1001-1     Document Type: Article

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