3′-Processing and strand transfer catalysed by retroviral integrase in crystallo

EMBO Journal

Volumn 31, Issue 13, 2012, Pages 3020-3028

  Hare, Stephen ^a   Maertens, Goedele N ^a   Cherepanov, Peter ^a,b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

inhibitor; integrase; mechanism; retrovirus; structure

Indexed keywords

INTEGRASE; RETROVIRUS INTEGRASE; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS ENZYME; DIVALENT CATION;

ARTICLE; CRYSTAL STRUCTURE; DNA STRAND; DNA STRUCTURE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; RETROVIRUS; RNA PROCESSING; SPUMA VIRUS; VIRUS DNA CELL DNA INTERACTION; CATALYSIS; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; HUMAN IMMUNODEFICIENCY VIRUS; METABOLISM; X RAY DIFFRACTION;

HUMAN SPUMARETROVIRUS;

CATALYSIS; CATALYTIC DOMAIN; CATIONS, DIVALENT; DNA, VIRAL; HIV; INTEGRASES; SPUMAVIRUS; VIRUS INTEGRATION; X-RAY DIFFRACTION;

EID: 84863823336     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.118     Document Type: Article

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