Prior morphine experience induces long-term increases in social interest and in appetitive behavior for natural reward

Behavioural Brain Research

Volumn 181, Issue 2, 2007, Pages 191-199

  Nocjar, Christine ^a,b   Panksepp, Jaak ^c  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^c WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Food seeking; Incentive sensitization; Morphine; Natural reward; Opiate addiction; Sexual pursuit; Social interest

Indexed keywords

MORPHINE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APPETITE; ARTICLE; COITUS; CONTROLLED STUDY; COPULATION; DRUG WITHDRAWAL; LONG TERM EXPOSURE; MALE; MOTIVATION; NONHUMAN; OPIATE ADDICTION; PRIORITY JOURNAL; RAT; REWARD; SEXUAL BEHAVIOR; SOCIAL ADAPTATION; SOCIAL BEHAVIOR;

ANALYSIS OF VARIANCE; ANIMALS; APPETITIVE BEHAVIOR; ASSOCIATION LEARNING; BEHAVIOR, ADDICTIVE; FEEDING BEHAVIOR; MALE; MORPHINE; NARCOTICS; RATS; RATS, LONG-EVANS; REWARD; SEXUAL BEHAVIOR, ANIMAL; SOCIAL BEHAVIOR;

EID: 34250375237     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2007.04.004     Document Type: Article

References (104)

1. Agmo A., and Paredes R. Opioids and sexual behavior in the male rat. Pharmacol Biochem Behav 30 (1988) 1021-1034
2. Agmo A., Turi A.L., Ellingsen E., and Kaspersen H. Preclinical models of sexual desire: conceptual and behavioral analyses. Pharmacol Biochem Behav 78 (2005) 379-404
3. Bakshi V.P., and Kelley A.E. Sensitization and conditioning of feeding following multiple morphine microinjections into the nucleus accumbens. Brain Res 648 (1994) 342-346
4. Barr A.M., Fiorino D.F., and Phillips A.G. Effects of withdrawal from an escalating dose schedule of d-amphetamine on sexual behavior in the male rat. Pharmacol Biochem Behav 64 (1999) 597-604
5. Barr A.M., and Phillips A.G. Withdrawal following repeated exposure to d-amphetamine decreases responding for a sucrose solution as measured by a progressive ratio schedule of reinforcement. Psychopharmacology 141 (1999) 99-106
6. Barrett A.C., Cook C.D., Terner J.M., Craft R.M., and Picker M.J. Importance of sex and relative efficacy at the mu opioid receptor in the development of tolerance and cross-tolerance to the antinociceptive effects of opioids. Psychopharmacology 158 (2001) 154-164
7. Berridge K.C. Food reward: brain substrates of wanting and liking. Neurosci Biobehav Rev 20 (1996) 1-25
8. Berridge K.C. Measuring hedonic impact in animals and infants: microstructure of affective taste reactivity patterns. Neurosci Biobehav Rev 24 (2000) 173-198
9. Berridge K.C., and Robinson T.E. What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?. Brain Res Rev 28 (1998) 309-369
10. Berridge K.C., and Valenstein E.S. What psychological process mediates feeding evoked by electrical stimulation of the lateral hypothalamus?. Behav Neurosci 105 (1991) 3-14
11. Bozarth M.A., and Wise R.A. Toxicity associated with long-term intravenous heroin and cocaine self-administration in the rat. JAMA 254 (1985) 81-83
12. Calsyn D.A., Roszell D.K., and Anderson L.S. Interpersonal style differences among drug abusers. J Clin Psychol 44 (1988) 821-830
13. Carden S.E., Hernandez N., and Hofer M.A. The isolation and companion comfort responses of 7- and 3-day-old rat pups are modulated by drugs active at the opioid receptor. Behav Neurosci 110 (1996) 324-330
14. Carden S.E., and Hofer M.A. The effects of opioid and benzodiazepine antagonists on dam-induced reductions in rat pup isolation distress. Dev Psychobiol 23 (1990) 797-808
15. Carroll K.M., Ball S.A., Nich C., O'Connor P.G., Eagan D.A., Frankforter T.L., et al. Targeting behavioral therapies to enhance naltrexone treatment of opioid dependence: efficacy of contingency management and significant other involvement. Arch Gen Psychiatry 58 (2001) 755-761
16. Covington III H.E., and Miczek K.A. Repeated social-defeat stress, cocaine or morphine effects on behavioral sensitization and intravenous cocaine self-administration. Psychopharmacology 158 (2001) 388-398
17. Cowan D.T., Allan L.G., Libretto S.E., and Griffiths P. Opioid drugs: a comparative survey of therapeutic and "Street" use. Pain Med 2 (2001) 193-203
18. Crowley T.J., Hydinger M., Stynes A.J., and Feiger A. Monkey motor stimulation and altered social behavior during chronic methadone administration. Psychopharmacologia 43 (1975) 135-144
19. Cui G.-H., Ren X.-W., Wu L.-Z., Han J.-S., and Cui C.-L. Electroacupuncture facilitates recovery of male sexual behavior in morphine withdrawal rats. Neurochem Res 29 (2004) 397-401
20. Cumberbatch Z., Copersino M., Stitzer M., and Jones H. Comparative drug use and psychosocial profiles of opioid dependents applying for medication versus medication-free treatment. Am J Drug Alcohol Abuse 30 (2004) 237-249
21. D'Amato F.R., and Pavone F. Endogenous opioids: a proximate reward mechanism for kin selection?. Neural Biol 60 (1993) 79-83
22. Deminiere J.M., Piazza P.V., Le Moal M., and Simon H. Experimental approach to individual vulnerability to psychostimulant addiction. Neurosci Biobehav Rev 13 (1989) 141-147
23. Deroche V., Le Moal M., and Piazza P.V. Cocaine self-administration increases the incentive motivational properties of the drug in rats. Eur J Neurosci 11 (1999) 2731-2736
24. Deroche-Gamonet V., Belin D., and Piazza P.V. Evidence for addiction-like behavior in the rat. Science 305 (2004) 1014-1017
25. Fabre-Nys D., Meller R.E., and Keverne E.B. Opiate antagonists stimulate affiliative behavior in monkeys. Pharmacol Biochem Behav 16 (1982) 653-659
26. Felip C.M., Rodriguez-Arias M., Espejo E.F., Minarro J., and Stinus L. Naloxone-induced opiate withdrawal produces long-lasting and context-independent changes in aggressive and social behaviors of postdependent male mice. Behav Neurosci 114 (2000) 424-430
27. Fiorino D.F., and Phillips A.G. Facilitation of sexual behavior and enhanced dopamine efflux in the nucleus accumbens of male rats after d-amphetamine-induced behavioral sensitization. J Neurosci 19 (1999) 456-463
28. Fiorino D.F., and Phillips A.G. Facilitation of sexual behavior in male rats following d-amphetamine-induced behavioral sensitization. Psychopharmacology 142 (1999) 200-208
29. Ford R.D., and Balster R.L. Schedule-controlled behavior in the morphine-dependent rat. Pharmacol Biochem Behav 4 (1976) 569-573
30. Gaiardi M., Bartoletti M., Bacchi A., Gubellini C., Costa M., and Babbini M. Role of repeated exposure to morphine in determining its affective properties: place and taste conditioning studies in rats. Psychopharmacology 103 (1991) 183-186
31. Galli G., and Wolffgramm J. Long-term voluntary d-amphetamine consumption and behavioral predictors for subsequent d-amphetamine addiction in rats. Drug Alcohol Depend 73 (2004) 51-60
32. Gerra G., Calbiani B., Zaimovic A., Sartori R., Ugolotti G., and Ippoligo L. Regional cerebral blood flow and comorbid diagnosis in abstinent opioid addicts. Psychiatry Res 83 (1998) 117-126
33. Gil K.M., Ginsberg B., Muir M., Sykes D., and Williams D.A. Patient-controlled analgesia in postoperative pain: the relation of psychological factors to pain and analgesic use. Clin J Pain 6 (1990) 137-142
34. Glenthoj B.Y., Mogensen J., Laursen H., and Hemmingsen R. Dopaminergic sensitization of rats with and without early prefrontal lesions: implications for the pathogenesis of schizophrenia. Int J Neuropsychopharmacol 2 (1999) 271-281
35. Gonzalez L.E., Rujano M., Tucci S., Paredes D., Silva E., Alba G., et al. Medial prefrontal transection enhances social interaction. I. Behavioral studies. Brain Res 887 (2000) 7-15
36. Gysling K., and Wang R.Y. Morphine-induced activation of A10 dopamine neurons in the rat. Brain Res 277 (1983) 119-127
37. Heyne A. The development of opiate addiction in the rat. Pharmacol Biochem Behav 53 (1996) 11-25
38. Hol T., Ruven S., Van Ree J.M., and Spruijt B.M. Chronic administration of Org2766 and morphine counteracts isolation-induced increase in social interest: implication of endogenous opioid systems. Neuropeptides 30 (1996) 283-291
39. Hol T., and Spruijt B.M. The MSH/ACTH(4-9) analog Org2766 counteracts isolation-induced enhanced social behavior via the amygdala. Peptides 13 (1992) 543-544
40. Holson R.R., Scallet A.C., Ali S.F., and Turner B.B. "Isolation stress" revisited: isolation-rearing effects depend on animal care methods. Physiol Behav 49 (1991) 1107-1118
41. Horger B.A., Giles M.K., and Schenk S. Preexposure to amphetamine and nicotine predisposes rats to self-administer a low dose of cocaine. Psychopharmacology 107 (1992) 271-276
42. Horger B.A., Shelton K., and Schenk S. Preexposure sensitizes rats to the rewarding effects of cocaine. Pharmacol Biochem Behav 37 (1990) 707-711
43. Horger B.A., Wellman P., Morien A., Davies B., and Schenk S. Caffeine exposure sensitizes rats to the reinforcing effects of cocaine. Neuroreport 2 (1991) 53-56
44. Ikemoto S., and Panksepp J. The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking. Brain Res Rev 31 (2000) 6-41
45. Johnson S.W., and North R.A. Opioids excite dopamine neurons by hyperpolarization of local interneurons. J Neurosci 12 (1992) 483-488
46. Joly D., and Sanger D.J. Social competition in rats: a test sensitive to acutely administered anxiolytics. Behav Pharmacol 2 (1991) 205-213
47. Kalin N.H., Shelton S.E., and Lynn D.E. Opiate systems in mother and infant primates coordinate intimate contact during reunion. Psychoneuroendocrinology 7 (1995) 735-742
48. Kalivas P.W., and Stewart J. Dopamine transmission in drug- and stress-induced behavioral sensitization. Brain Res Rev 16 (1991) 223
49. Kehoe P., and Shoemaker W. Opioid-dependent behaviors in infant rats: effects of prenatal exposure to ethanol. Pharmacol Biochem Behav 39 (1991) 389-394
50. Kelley A.E. Ventral striatal control of appetitive motivation: role in ingestive behavior and reward-related learning. Neurosci Biobehav Rev 27 (2004) 765-776
51. Kelley A.E., and Berridge K.C. The neuroscience of natural rewards: relevance to addictive drugs. J Neurosci 22 (2002) 3306-3311
52. Keverne E.B., Martensz N., and Tuite B. β-endorphin concentrations in CSF of monkeys are influenced by grooming relationships. Psychoneuroendocrinology 14 (1989) 455-464
53. Klitenick M.A., DeWitte P., and Kalivas P.W. Regulation of somatodendritic dopamine release in the ventral tegmental area by opioids and GABA: an in vivo microdialysis study. J Neurosci 12 (1992) 2623-2632
54. Kraus M.A., Piper J.M., and Kornetsky C. Persistent increases in basal cerebral metabolic activity induced by morphine sensitization. Pharmacol Biochem Behav 57 (1997) 89-100
55. Kumar R., Mumford L., and Teixeira A.R. Sexual behaviour in morphine-dependent rats. Br J Pharmacol 62 (1978) 389-390
56. Lett B.T. Repeated exposures intensify rather than diminish the rewarding effects of amphetamine, morphine, and cocaine. Psychopharmacology 98 (1989) 357-362
57. Lieblich I., Yirmiya R., and Liebeskind J.C. Intake of and preference for sweet solutions are attenuated in morphine withdrawn rats. Behav Neurosci 105 (1991) 965-970
58. Lorrain D.S., Arnold G.M., and Vezina P. Previous exposure to amphetamine increases incentive to obtain the drug: long-lasting effects revealed by the progressive ratio schedule. Behav Brain Res 107 (2000) 9-19
59. Matthews R.T., and German D.C. Electrophysiological evidence for excitation of rat ventral tegmental area dopaminergic neurons by morphine. Neuroscience 11 (1984) 617-626
60. Mendrek A., Blaha C.D., and Phillips A.G. Pre-exposure of rats to amphetamine sensitizes self-administration of this drug under a progressive ratio schedule. Psychopharmacology 135 (1998) 416-422
61. Meyerson B.J. Comparison of the effects of β-endorphin and morphine on exploratory and social-sexual behaviour in the male rat. Eur J Pharmacol 69 (1981) 453-463
62. Miczek K.A., and Mutschler N.H. Activational effects of social stress on IV cocaine self-administration in rats. Psychopharmacology 128 (1996) 256-264
63. Mitchell J.B., and Stewart J. Facilitation of sexual behaviors in the male rat in the presence of stimuli previously paired with systemic injections of morphine. Pharmacol Biochem Behav 35 (1990) 367-372
64. Mumford L., and Kumar R. Sexual behaviour of morphine-dependent and abstinent male rats. Psychopharmacology 65 (1979) 179-185
65. Niesink R.J.M., and Van Ree J.M. Normalizing effect of an adrenocorticotropic hormone (4-9) analog ORG 2766 on disturbed social behavior in rats. Science 221 (1983) 960-962
66. Nocjar C., Ikemoto S., and Yamamoto B.K. Glutamatergic mechanisms from subdivisions of the prefrontal cortex differentially regulate appetitive behavior for drug vs. natural reward following amphetamine experience. Soc Neurosci Abstr 917 (2005) 10
67. Nocjar C., and Panksepp J. Chronic intermittent amphetamine pretreatment enhances future appetitive behavior for drug- and natural-reward: interaction with environmental variables. Behav Brain Res 128 (2002) 189-203
68. Panksepp J. Brain opioids: a neurochemical substrate for narcotic and social dependence. In: Cooper S. (Ed). Progress in theory in psychopharmacology. (1981), Academic Press, London 149-175
69. Panksepp J. Toward a general psychobiological theory of emotions. Behav Brain Sci 5 (1982) 407-467
70. 3H] diprenorphine binding in the rat brain: effects of social interaction. Brain Res Bull 7 (1981) 405-410
71. Panksepp J., Herman B.H., Conner R., Bishop P., and Scott J.P. The biology of social attachments: opiates alleviate separation distress. Biol Psychiatry 13 (1978) 607-618
72. Panksepp J., Herman B.H., Villberg T., Bishop P., and DeEskinazi F.G. Endogenous opioids and social behavior. Neurosci Biobehav Rev 4 (1980) 473-487
73. Panksepp J., Knutson B., and Burgdorf J. The role of brain emotional systems in addictions: a neuro-evolutionary perspective and new 'self-report' animal model. Addiction 97 (2002) 459-469
74. Panksepp J., Lensing P., Leboyer M., and Bouvard M.P. Naltrexone and other potential new pharmacological treatments of autism. Brain Dysfunct 4 (1991) 281-300
75. Panksepp J., Najam N., and Soares F. Morphine reduces social cohesion in rats. Pharmacol Biochem Behav 11 (1979) 131-134
76. Panksepp J., Nelson E., and Bekkedal M. Brain systems for the mediation of social separation-distress and social-reward. Evolutionary antecedents and neuropeptide intermediaries. Ann NY Acad Sci 807 (1997) 78-100
77. Panksepp J., Nelson E., and Siviy S.M. Brain opioids and mother-infant social motivation. Acta Paediatr Suppl 397 (1994) 40-46
78. Panksepp J., Nocjar C., Burgdorf J., Panksepp J.B., and Huber R. The role of emotional systems in addiction: a neuroethological perspective. Nebraska Symposium on Addiction, vol. 50 (2004) 85-126
79. Panksepp J., Normansell L.A., Herman B.H., Bishop P., and Crepeau L. Neural and neurochemical control of the separation distress call. In: Newman J.D. (Ed). The physiological control of mammalian vocalizations (1988), Plenum Press, New York 263-299
80. Panksepp J., and Siviy S.M. Normansell LA: brain opioids and social emotion. In: Reite M., and Fields T. (Eds). The psychobiology of attachment and separation (1985), Academic Press, New York 3-49
81. Pecina S., and Berridge K.C. Opioid site in nucleus accumbens shell mediates eating and hedonic 'liking' for food: map based on microinjection Fos plumes. Brain Res 863 (2000) 71-86
82. Pierre P.J., and Vezina P. Predisposition to self-administer amphetamine: the contribution of response to novelty and prior exposure to the drug. Psychopharmacology 129 (1997) 277-284
83. Plonsky M., and Freeman P.R. The effects of methadone on the social behavior and activity of the rat. Pharmacol Biochem Behav 16 (1982) 569-571
84. Puglisi-Allegra S., Oliverio A., and Mandel P. Effects of opiate antagonists on social and aggressive behavior of isolated mice. Pharmacol Biochem Behav 17 (1982) 691-694
85. Richman A., and Dunham H.W. A sociological theory of the diffusion and social setting of opiate addiction. Drug Alcohol Depend 1 (1976) 383-389
86. Robinson T.E., and Berridge K.C. The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res Rev 18 (1993) 247-291
87. Schenk S., Valadez A., McNamara C., House D.T., Higley D., Bankson M.G., et al. Development and expression of sensitization to cocaine's reinforcing properties: role of NMDA receptors. Psychopharmacology 111 (1993) 332-338
88. Shippenberg T.S., Emmett-Oglesby M.W., Ayesta J., and Herz A. Tolerance and selective cross-tolerance to the motivational effects of opioids. Psychopharmacology 96 (1988) 110-115
89. Shippenberg T.S., and Heidbreder Ch. Sensitization to the conditioned rewarding effects of cocaine: pharmacological and temporal characteristics. J Pharmacol Exp Ther 273 (1995) 808-815
90. Shippenberg T.S., Heidbreder Ch, and Lefevour A. Sensitization to the conditioned rewarding effects of morphine: pharmacology and temporal characteristics. Eur J Pharmacol 299 (1996) 33-39
91. Steinfels G.F., and Young G.A. Effects of narcotic abstinence on schedule-controlled behavior in dependent rats. Pharmacol Biochem Behav 14 (1981) 393-395
92. Sufka K.J., Hughes R.A., McCormick T.M., and Borland J.L. Opiate effects on isolation stress in domestic fowl. Pharmacol Biochem Behav 49 (1994) 1011-1015
93. Suto N., Austin J.D., Tanabe L.M., Kramer M.K., Wright D.A., and Vezina P. Previous exposure to VTA amphetamine enhances cocaine self-administration under a progressive ratio schedule in a D1 dopamine receptor dependent manner. Neuropsychopharmacology 27 (2002) 970-979
94. Svingos A.L., Garzon M., Colago E.E., and Pickel V.M. Mu-opioid receptors in the ventral tegmental area are targeted to presynaptically and directly modulate mesocortical projection neurons. Synapse 41 (2001) 221-229
95. Tzschentke T.M., and Schmidt W.J. Procedural examination of behavioural sensitization to morphine: lack of blockade by MK-801, occurrence of sensitised sniffing, and evidence for cross-sensitization between morphine and MK-801. Behav Pharmacol 7 (1996) 169-184
96. Valadez A., and Schenk S. Persistence of the ability of amphetamine preexposure to facilitate acquisition of cocaine self-administration. Pharmacol Biochem Behav 47 (1994) 203-205
97. Van den Berg C.L., Kitchen I., Gerrits M.A.F.M., Spruijt B.M., and Van Ree J.M. Morphine treatment during juvenile isolation increases social activity and opioid peptides release in the adult rat. Brain Res 830 (1999) 16-23
98. Van den Berg C.L., Van Ree J.M., and Spruijt B.M. Morphine attenuates the effects of juvenile isolation in rats. Neuropharmacology 39 (2000) 969-976
99. Van den Berg C.L., Van Ree J.M., Spruijt B.M., and Kitchen I. Effects of juvenile isolation and morphine treatment on social interactions and opioid receptors in adult rats: behavioral and autoradiographic studies. Eur J Neurosci 11 (1999) 3023-3032
100. Vanderschuren L.J.M.J., and Everitt B.J. Drug seeking becomes compulsive after prolonged cocaine self-administration. Science 305 (2004) 1017-1019
101. Vanderschuren L.J.M.J., and Kalivas P.W. Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies. Psychopharmacology 151 (2000) 99-120
102. Vezina P., Lorrain D.S., Arnold G.M., Austin J.D., and Suto N. Sensitization of midbrain dopamine neuron reactivity promotes the pursuit of amphetamine. J Neurosci 22 (2002) 4654-4662
103. Vilberg T.R., Panksepp J., Kastin A.J., and Coy D.H. The pharmacology of endorphin modulation of chick distress vocalization. Peptides 5 (1984) 823-827
104. Yokel R., and Pickens R. Self-administration of optical isomers of amphetamine and methylamphetamine by rats. J Pharmacol Exp Ther 187 (1973) 27-33