Inter and intra-ethnic differences in the distribution of the molecular variants of TPMT, UGT1A1 and MDR1 genes in the South Indian population

Molecular Biology Reports

Volumn 39, Issue 5, 2012, Pages 6343-6351

  Umamaheswaran, Gurusamy ^a   Kumar, Dhakchinamoorthi Krishna ^a   Kayathiri, Dhandapani ^a   Rajan, Subramanian ^a   Shewade, Deepak Gopal ^a   Dkhar, Steven Aibor ^a   Manjunath, Sajjanavar ^b   Ushakiran, Prayaga ^c   Reneega, Gangadharan ^d   Ritushree, Kukreti ^e   Adithan, Chandrasekaran ^a  

^a JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

^b M R MEDICAL COLLEGE   (India)

^c Rangaraya Medical College   (India)

^d GOVERNMENT MEDICAL COLLEGE   (India)

^e CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

Author keywords

MDR1; Polymorphism; South Indians; TPMT; UGT1A1

Indexed keywords

DRUG METABOLIZING ENZYME; GENOMIC DNA; GLUCURONOSYLTRANSFERASE 1A1; MULTIDRUG RESISTANCE PROTEIN 1; THIOPURINE METHYLTRANSFERASE; ABCB1 PROTEIN, HUMAN; BILIRUBIN URIDINE DIPHOSPHOGLUCURONOSYL TRANSFERASE 1A1; BILIRUBIN URIDINE-DIPHOSPHOGLUCURONOSYL TRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE; GLYCOPROTEIN P; METHYLTRANSFERASE;

ADULT; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ETHNIC DIFFERENCE; FEMALE; GENE; GENE FREQUENCY; GENE IDENTIFICATION; GENE MUTATION; GENETIC HETEROGENEITY; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN EXPERIMENT; INDIAN; MALE; MDR1 GENE; NORMAL HUMAN; POPULATION GENETICS; REAL TIME POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; TPMT GENE; UGT1A1 GENE; ADOLESCENT; ALLELE; ETHNIC GROUP; GENETICS; INDIA; MIDDLE AGED;

ADOLESCENT; ADULT; ALLELES; ETHNIC GROUPS; GENE FREQUENCY; GLUCURONOSYLTRANSFERASE; HUMANS; INDIA; METHYLTRANSFERASES; MIDDLE AGED; P-GLYCOPROTEIN; POLYMORPHISM, SINGLE NUCLEOTIDE; YOUNG ADULT;

EID: 84863757762     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-1456-8     Document Type: Article

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