메뉴 건너뛰기




Volumn 28, Issue 4, 2011, Pages 1549-1554

MDR-1 polymorphisms (G2677T and C3435T) in B-chronic lymphocytic leukemia: An impact on susceptibility and prognosis

Author keywords

B chronic lymphocytic leukemia; Gene polymorphism; MDR1; Prognostic marker

Indexed keywords

IMMUNOGLOBULIN; IMMUNOGLOBULIN VH; MULTIDRUG RESISTANCE PROTEIN 1; UNCLASSIFIED DRUG;

EID: 84655165078     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-010-9561-9     Document Type: Article
Times cited : (21)

References (37)
  • 1
    • 0028276447 scopus 로고
    • Multidrug resistance phenotype in patients with chronic lymphocytic leukemia as detected by immunofluorescence (FACS) and northen blot analysis
    • G Wulf 1994 Multidrug resistance phenotype in patients with chronic lymphocytic leukemia as detected by immunofluorescence (FACS) and northen blot analysis Leuk Res 18 475 484
    • (1994) Leuk Res , vol.18 , pp. 475-484
    • Wulf, G.1
  • 2
    • 0032168144 scopus 로고    scopus 로고
    • Pharmacogenetics and cancer chemotherapy
    • L Iyer MJ Raain 1998 Pharmacogenetics and cancer chemotherapy Eur J Cancer 34 1493 1499
    • (1998) Eur J Cancer , vol.34 , pp. 1493-1499
    • Iyer, L.1    Raain, M.J.2
  • 3
    • 0037131893 scopus 로고    scopus 로고
    • The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans
    • MF Fromm 2002 The influence of MDR1 polymorphisms on P-glycoprotein expression and function in humans Adv Drug Deliv Rev 54 1295 1310
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 1295-1310
    • Fromm, M.F.1
  • 4
    • 2542622040 scopus 로고    scopus 로고
    • Pharmacogenomics of MDR1/ABCB1 gene: The influence on risk and clinical outcome of haematological malignancies
    • K Jamroziak T Robak 2004 Pharmacogenomics of MDR1/ABCB1 gene: the influence on risk and clinical outcome of haematological malignancies Hematology 9 91 105
    • (2004) Hematology , vol.9 , pp. 91-105
    • Jamroziak, K.1    Robak, T.2
  • 5
    • 1642523162 scopus 로고    scopus 로고
    • Polimorphorsms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
    • C Marzolini E Paulus T Buclin RB Kim 2004 Polimorphorsms in human MDR1 (P-glycoprotein): recent advances and clinical relevance Clin Pharmacol Ther 75 13 33
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 13-33
    • Marzolini, C.1    Paulus, E.2    Buclin, T.3    Kim, R.B.4
  • 6
    • 3042772026 scopus 로고    scopus 로고
    • Identification of functionally variant MDR1 alleles among European Americans and African Americans
    • RB Kim 2001 Identification of functionally variant MDR1 alleles among European Americans and African Americans Clin Pharmacol Ther 70 189 199
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 189-199
    • Kim, R.B.1
  • 7
    • 33645691608 scopus 로고    scopus 로고
    • Multidrug resistance-1 gene polymorphisms associated with treatment outcomes in the novo acute myeloid leukemia
    • RB Kim 2005 Multidrug resistance-1 gene polymorphisms associated with treatment outcomes in the novo acute myeloid leukemia Int J Cancer 118 2195 2201
    • (2005) Int J Cancer , vol.118 , pp. 2195-2201
    • Kim, R.B.1
  • 8
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • S Hoffmeyer 2000 Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo Proc Natl Acad Sci USA 97 3473 3478
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3473-3478
    • Hoffmeyer, S.1
  • 9
    • 0034971274 scopus 로고    scopus 로고
    • The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells
    • M Hitzl 2001 The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells Pharmacogenetics 11 293 298
    • (2001) Pharmacogenetics , vol.11 , pp. 293-298
    • Hitzl, M.1
  • 10
    • 13444252391 scopus 로고    scopus 로고
    • MDR1 and MRP1 gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia
    • M Schaich S Sourcek C Thiede G Ehninger T Ilmer 2005 MDR1 and MRP1 gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia Br J Haematol 128 324 332
    • (2005) Br J Haematol , vol.128 , pp. 324-332
    • Schaich, M.1    Sourcek, S.2    Thiede, C.3    Ehninger, G.4    Ilmer, T.5
  • 11
    • 23844440902 scopus 로고    scopus 로고
    • Multidrug resistance as a potential prognostic indicator in acute myeoid leukemia with normal karyotypes
    • DH Kim 2005 Multidrug resistance as a potential prognostic indicator in acute myeoid leukemia with normal karyotypes Acta Haematol 114 78 83
    • (2005) Acta Haematol , vol.114 , pp. 78-83
    • Kim, D.H.1
  • 12
    • 33745081866 scopus 로고    scopus 로고
    • Genomic polymorphisms provide prognostic information in intermediate-risk acute myeloblastic leukemia
    • M Monzo 2006 Genomic polymorphisms provide prognostic information in intermediate-risk acute myeloblastic leukemia Blood 107 4871 4879
    • (2006) Blood , vol.107 , pp. 4871-4879
    • Monzo, M.1
  • 13
    • 19944432158 scopus 로고    scopus 로고
    • GSTP1 and MDR1 genotypes and central nervous system relapse in childhood acute lymphoblastic leukemia
    • M Stanulla 2005 GSTP1 and MDR1 genotypes and central nervous system relapse in childhood acute lymphoblastic leukemia Int J Hematol 81 39 44
    • (2005) Int J Hematol , vol.81 , pp. 39-44
    • Stanulla, M.1
  • 14
    • 33751087230 scopus 로고    scopus 로고
    • ABCB1 gene polymorphisms are not associated with treatment outcome in elderly acute myeloid leukemia patients
    • B Van der Holt 2006 ABCB1 gene polymorphisms are not associated with treatment outcome in elderly acute myeloid leukemia patients Clin Pharmacol Ther 80 427 439
    • (2006) Clin Pharmacol Ther , vol.80 , pp. 427-439
    • Van Der Holt, B.1
  • 15
    • 34247889831 scopus 로고    scopus 로고
    • MDR1 polymorphism influences the outcome of multiple myeloma patients
    • G Buda 2007 MDR1 polymorphism influences the outcome of multiple myeloma patients Br J Haematol 137 454 456
    • (2007) Br J Haematol , vol.137 , pp. 454-456
    • Buda, G.1
  • 16
    • 42149099346 scopus 로고    scopus 로고
    • MDR1 diplotypes as prognostic markers in multiple myeloma
    • V Maggini 2008 MDR1 diplotypes as prognostic markers in multiple myeloma Pharmacogenet Genomics 18 383 389
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 383-389
    • Maggini, V.1
  • 17
    • 33745741965 scopus 로고    scopus 로고
    • The association between multidrug resistance-1 gene polymorphisms and outcomes of allogenic HLA-identical stem cell transplantation
    • DH Kim JY Park SK Sohn NY Lee KB Lee 2006 The association between multidrug resistance-1 gene polymorphisms and outcomes of allogenic HLA-identical stem cell transplantation Haematologica 91 848 851
    • (2006) Haematologica , vol.91 , pp. 848-851
    • Kim, D.H.1    Park, J.Y.2    Sohn, S.K.3    Lee, N.Y.4    Lee, K.B.5
  • 18
    • 52649177063 scopus 로고    scopus 로고
    • Multidrug resistance gene (MDR1) polymorphisms are associated with major molecular responses to standard-dose imatinib in chronic myeloid leukemia
    • S Dulucq 2008 Multidrug resistance gene (MDR1) polymorphisms are associated with major molecular responses to standard-dose imatinib in chronic myeloid leukemia Blood 112 2024 2027
    • (2008) Blood , vol.112 , pp. 2024-2027
    • Dulucq, S.1
  • 19
    • 0036729669 scopus 로고    scopus 로고
    • The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in paediatric heart transplant patients
    • H Zheng 2002 The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in paediatric heart transplant patients Him Immunol 63 765 770
    • (2002) Him Immunol , vol.63 , pp. 765-770
    • Zheng, H.1
  • 20
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • TJ Hamblin Z Davis A Gardiner DG Oscier FK Stevenson 1999 Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia Blood 94 1848 1854
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 21
    • 79952247981 scopus 로고    scopus 로고
    • Multidrug resistance gene (MDR1) polymorphisms correlate with imatinib response in chronic myeloid leukemia
    • Mar 4. [Epub ahead of print]
    • Ni LN et al. Multidrug resistance gene (MDR1) polymorphisms correlate with imatinib response in chronic myeloid leukemia. Med Oncol. 2010 Mar 4. [Epub ahead of print].
    • (2010) Med Oncol.
    • Ni, L.N.1
  • 22
  • 23
    • 65549087976 scopus 로고    scopus 로고
    • Association of C3435T single-nucleotide polymorphism of MDR1 gene with breast cancer in an Iranian population
    • F Tatari 2009 Association of C3435T single-nucleotide polymorphism of MDR1 gene with breast cancer in an Iranian population DNA Cell Biol 28 259 263
    • (2009) DNA Cell Biol , vol.28 , pp. 259-263
    • Tatari, F.1
  • 24
    • 1642473017 scopus 로고    scopus 로고
    • Possible prediction of the efficiency of chemotherapy in patients with lymphoproliferative diseases based on MDR1 gene G2677T and C3435T polymorphisms
    • OB Goreva AY Grishanova OV Mukhin NP Domnikova VV Lyakhovich 2003 Possible prediction of the efficiency of chemotherapy in patients with lymphoproliferative diseases based on MDR1 gene G2677T and C3435T polymorphisms Bull Exp Biol Med 136 183 185
    • (2003) Bull Exp Biol Med , vol.136 , pp. 183-185
    • Goreva, O.B.1    Grishanova, A.Y.2    Mukhin, O.V.3    Domnikova, N.P.4    Lyakhovich, V.V.5
  • 25
    • 56949102507 scopus 로고    scopus 로고
    • Polymorphisms and haplotypes in the multidrug resistance 1 gene (MDR1/ABCB1) and risk of multiple myeloma
    • K Jamroziak 2009 Polymorphisms and haplotypes in the multidrug resistance 1 gene (MDR1/ABCB1) and risk of multiple myeloma Leuk Res 33 332 335
    • (2009) Leuk Res , vol.33 , pp. 332-335
    • Jamroziak, K.1
  • 26
    • 0027079910 scopus 로고
    • PCR-determined expression of the MDR1 gene in chronic lymphocytic leukemia
    • CF Rochlitz 1992 PCR-determined expression of the MDR1 gene in chronic lymphocytic leukemia Ann Hematol 65 241 246
    • (1992) Ann Hematol , vol.65 , pp. 241-246
    • Rochlitz, C.F.1
  • 27
    • 34547993284 scopus 로고    scopus 로고
    • Multi-drug resistance mediated by P-glycoprotein overexpression is not correlated with ZAP-70/CD38 expression in B-cell chronic lymphocytic leukemia
    • N Guillaume 2007 Multi-drug resistance mediated by P-glycoprotein overexpression is not correlated with ZAP-70/CD38 expression in B-cell chronic lymphocytic leukemia Leuk Lymphoma 48 1468 1469
    • (2007) Leuk Lymphoma , vol.48 , pp. 1468-1469
    • Guillaume, N.1
  • 28
    • 0032620210 scopus 로고    scopus 로고
    • A mutation in the promoter of the multidrug resistance gene (MDR1) in human hematological malignancies may contribute to the pathogenesis of resistant disease
    • D Rund I Azar O Shperling 1999 A mutation in the promoter of the multidrug resistance gene (MDR1) in human hematological malignancies may contribute to the pathogenesis of resistant disease Adv Exp Med Biol 457 71 75
    • (1999) Adv Exp Med Biol , vol.457 , pp. 71-75
    • Rund, D.1    Azar, I.2    Shperling, O.3
  • 29
    • 1942532906 scopus 로고    scopus 로고
    • Functional C3435T polymorphism of MDR1 gene: An impact on genetic susceptibly and clinical outcome of childhood acute lymphoblastic leukemia
    • K Jamroziak 2004 Functional C3435T polymorphism of MDR1 gene: an impact on genetic susceptibly and clinical outcome of childhood acute lymphoblastic leukemia Eur J Haematol 72 314 321
    • (2004) Eur J Haematol , vol.72 , pp. 314-321
    • Jamroziak, K.1
  • 30
    • 35748937668 scopus 로고    scopus 로고
    • Regulatory polymorphisms of multidrug resistance 1 (MDR1) gene are associated with the development of childhood acute lymphoblastic leukemia
    • H Hattori 2007 Regulatory polymorphisms of multidrug resistance 1 (MDR1) gene are associated with the development of childhood acute lymphoblastic leukemia Leuk Res 31 1633 1640
    • (2007) Leuk Res , vol.31 , pp. 1633-1640
    • Hattori, H.1
  • 31
    • 0033105657 scopus 로고    scopus 로고
    • Susceptibility to childhood lymphoblastic leukemia: Influence of CYP1a1, CYP2D6, GSTM1 and GSTT1 genetic polymorphism
    • M Krajinovic D Labuda C Richier S Karimi D Sinnett 1999 Susceptibility to childhood lymphoblastic leukemia: influence of CYP1a1, CYP2D6, GSTM1 and GSTT1 genetic polymorphism Blood 93 496 1501
    • (1999) Blood , vol.93 , pp. 496-1501
    • Krajinovic, M.1    Labuda, D.2    Richier, C.3    Karimi, S.4    Sinnett, D.5
  • 32
    • 0036225455 scopus 로고    scopus 로고
    • Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability
    • U Potocnik M Ravnik-Glavac D Glavac 2002 Functional MDR1 polymorphisms (G2677T and C3435T) and TCF4 mutations in colorectal tumors with high microsatellite instability Cell Mol Biol Lett 7 92 95
    • (2002) Cell Mol Biol Lett , vol.7 , pp. 92-95
    • Potocnik, U.1    Ravnik-Glavac, M.2    Glavac, D.3
  • 33
    • 0035667325 scopus 로고    scopus 로고
    • Anti-P-glycoprotein antibody-induced apoptosis of activated peripheral blood lymphocytes: A possible role of P-glycoprotein in lymphocyte survival
    • S Golapud S Gupta 2001 Anti-P-glycoprotein antibody-induced apoptosis of activated peripheral blood lymphocytes: a possible role of P-glycoprotein in lymphocyte survival J Clin Immunol 21 420 430
    • (2001) J Clin Immunol , vol.21 , pp. 420-430
    • Golapud, S.1    Gupta, S.2
  • 34
    • 33751074914 scopus 로고    scopus 로고
    • MDR-1, but not MDR-3 gene expression, is associated with unmutated IgVh genes and poor prognosis chromosomal aberrations in chronic lymphocytic leukemia
    • C Mattews 2006 MDR-1, but not MDR-3 gene expression, is associated with unmutated IgVh genes and poor prognosis chromosomal aberrations in chronic lymphocytic leukemia Leuk Lymph 47 2308 2313
    • (2006) Leuk Lymph , vol.47 , pp. 2308-2313
    • Mattews, C.1
  • 35
    • 28844432455 scopus 로고    scopus 로고
    • Involvement of C3435T and G 2677T multidrug resistance gene polymorphisms in release of cytokines from peripheral blood mononuclear cells treated with methotrexate and dexamethasone
    • A Pawlik M Baskiewicz-Masiuk B Machalinski M Kurzawski B Gawronska-Szklarz 2005 Involvement of C3435T and G 2677T multidrug resistance gene polymorphisms in release of cytokines from peripheral blood mononuclear cells treated with methotrexate and dexamethasone Eur J Pharmacol 528 27 36
    • (2005) Eur J Pharmacol , vol.528 , pp. 27-36
    • Pawlik, A.1    Baskiewicz-Masiuk, M.2    MacHalinski, B.3    Kurzawski, M.4    Gawronska-Szklarz, B.5
  • 36
    • 84655172555 scopus 로고    scopus 로고
    • Abnormal immunity and stem/progenitor cells in acquired aplastic anemia
    • Epub ahead of print
    • Li JP, Zhang CL, Han ZC. Abnormal immunity and stem/progenitor cells in acquired aplastic anemia. Crit Rev Oncol Hematol. 2009. Epub ahead of print.
    • (2009) Crit Rev Oncol Hematol
    • Li, J.P.1    Zhang, C.L.2    Han, Z.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.