Gliclazide may have an antiapoptotic effect related to its antioxidant properties in human normal and cancer cells

Molecular Biology Reports

Volumn 39, Issue 5, 2012, Pages 5253-5267

  Sliwinska, Agnieszka ^a   Rogalska, Aneta ^b   Szwed, Marzena ^b   Kasznicki, Jacek ^a   Jozwiak, Zofia ^b   Drzewoski, Jozef ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b UNIVERSITY OF LODZ   (Poland)

Author keywords

Apoptosis; Calcium; Gliclazide; Mitochondrial membrane potential; Reactive oxygen species

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CALCIUM ION; GLICLAZIDE; HYDROGEN PEROXIDE; PROPIDIUM IODIDE; REACTIVE OXYGEN METABOLITE; ANTIOXIDANT; CALCIUM; ION;

ADULT; AGED; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CANCER CELL CULTURE; CASE REPORT; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG DETERMINATION; DRUG EFFECT; DRUG MECHANISM; FEMALE; HUMAN; HUMAN CELL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; CELL DEATH; CELL SHAPE; CELL SURVIVAL; CYTOLOGY; FLUORESCENCE MICROSCOPY; INTRACELLULAR SPACE; METABOLISM; TUMOR CELL LINE; UMBILICAL VEIN ENDOTHELIAL CELL;

ANTIOXIDANTS; APOPTOSIS; CALCIUM; CELL DEATH; CELL LINE, TUMOR; CELL SHAPE; CELL SURVIVAL; GLICLAZIDE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; INTRACELLULAR SPACE; IONS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, FLUORESCENCE;

EID: 84863755010     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-011-1323-z     Document Type: Article

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