Differential effect of sulfonylureas on production of reactive oxygen species and apoptosis in cultured pancreatic β-cell line, MIN6

Metabolism: Clinical and Experimental

Volumn 57, Issue 8, 2008, Pages 1038-1045

  Sawada, Fumi ^a   Inoguchi, Toyoshi ^a   Tsubouchi, Hirotaka ^a   Sasaki, Shuji ^a   Fujii, Masakazu ^a   Maeda, Yasutaka ^a   Morinaga, Hidetaka ^a   Nomura, Masatoshi ^a   Kobayashi, Kunihisa ^a   Takayanagi, Ryoichi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; APOCYNIN; CALPHOSTIN C; DEOXYURIDINE TRIPHOSPHATE DERIVATIVE; DICHLORODIHYDROFLUORESCEIN DIACETATE; DIPHENYLIODONIUM SALT; DNA NUCLEOTIDYLEXOTRANSFERASE; GLIBENCLAMIDE; GLICLAZIDE; GLIMEPIRIDE; NATEGLINIDE; PROTEIN KINASE C INHIBITOR; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; MOUSE; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CELL LINE; CYCLOHEXANES; FLUORESCEINS; GLICLAZIDE; GLYBURIDE; HYPOGLYCEMIC AGENTS; IN SITU NICK-END LABELING; INSULIN-SECRETING CELLS; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; NADPH OXIDASE; PHENYLALANINE; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; SULFONYLUREA COMPOUNDS;

EID: 47149092657     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2008.01.038     Document Type: Article

References (29)

1. Butler A.E., Janson J., Bonner-Weir S., et al. β-Cell deficit and increased β-cell apoptosis in humans with type 2 diabetes. Diabetes 52 (2003) 102-110
2. Ritzel R.A., Butler A.E., Rizza R.A., et al. Relationship between β-cell mass and fasting blood glucose concentration in humans. Diabetes Care 29 (2006) 717-718
3. Unger R.H., and Grundy S. Hyperglycaemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance: implications for the management of diabetes. Diabetologia 28 (1985) 119-121
4. Leahy J.L., Bonner-Weir S., and Weir G.C. Beta-cell dysfunction induced by chronic hyperglycemia. Current ideas on mechanism of impaired glucose-induced insulin secretion. Diabetes Care 15 (1992) 442-455
5. Robertson R.P. Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes. J Biol Chem 279 (2004) 42351-42354
6. Federici M., Hribal M., Perego L., et al. High glucose causes apoptosis in cultured human pancreatic islets of Langerhans. Diabetes 50 (2001) 1290-1301
7. Ihara Y., Toyokuni S., Uchida K., et al. Hyperglycemia causes oxidative stress in pancreatic β-cells of GK rats, a model of type 2 diabetes. Diabetes 48 (1999) 927-932
8. Tanaka Y., Gleason C.E., Tran P.O., et al. Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants. Proc Natl Acad Sci USA 96 (1999) 10857-10862
9. Tanaka Y., Tran P.O., Harmon J., et al. A role for glutathione peroxidase in protecting pancreatic β cells against oxidative stress in a model of glucose toxicity. Proc Natl Acad Sci USA 99 (2002) 12363-12368
10. Sakuraba H., Mizukami H., Yagihashi N., et al. Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese type 2 diabetic patients. Diabetologia 45 (2002) 85-96
11. Bindokas V.P., Kuznetsov A., Sreenan S., et al. Visualizing superoxide production in normal and diabetic rat islets of Langerhans. J Biol Chem 278 (2003) 9796-9801
12. Efanova I.B., Zaitsev S.V., Zhivotovsky B., et al. Glucose and tolbutamide induce apoptosis in pancreatic β-cells. J Biol Chem 273 (1998) 33501-33507
13. 2+ influx by glibenclamide induces apoptosis in RINm5F cells. Biochem Biophys Res Commun 271 (2000) 422-428
14. Tsubouchi H., Inoguchi T., Inuo M., et al. Sulfonylurea as well as elevated glucose levels stimulate reactive oxygen species production in the pancreatic β-cell line, MIN6-a role of NAD(P)H oxidase in β-cells. Biochem Biophys Res Commun 326 (2005) 60-65
15. Alvarsson M., Sundkvist G., Lager I., et al. Beneficial effects of insulin versus sulphonylurea on insulin secretion and metabolic control in recently diagnosed type 2 diabetic patients. Diabetes Care 26 (2003) 2231-2237
16. Kaneto H., Kajimoto Y., Miyagawa J., et al. Beneficial effects of antioxidants in diabetes: possible protection of pancreatic β-cells against glucose toxicity. Diabetes 48 (1999) 2398-2406
17. Green K., Brand M.D., and Murphy M.P. Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes. Diabetes 53 Suppl 1 (2004) S110-S118
18. Griendling K.K., Sorescu D., and Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 86 (2000) 494-501
19. Inoguchi T., Li P., Umeda F., et al. High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes 49 (2000) 1939-1945
20. Guzik T.J., Mussa S., Gastaldi D., et al. Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation 105 (2002) 1656-1662
21. Sonta T., Inoguchi T., Tsubouchi H., et al. Evidence for contribution of vascular NAD(P)H oxidase to increased oxidative stress in animal models of diabetes and obesity. Free Radic Biol Med 37 (2004) 115-123
22. Oliveira H.R., Verlengia R., Carvalho C.R., et al. Pancreatic β-cells express phagocyte-like NAD(P)H oxidase. Diabetes 52 (2003) 1457-1463
23. Uchizono Y., Takeya R., Iwase M., et al. Expression of isoforms of NADPH oxidase components in rat pancreatic islets. Life Sci 80 (2006) 133-139
24. Kimoto K., Suzuki K., Kizaki T., et al. Gliclazide protects pancreatic β-cells from damage by hydrogen peroxide. Biochem Biophys Res Commun 303 (2003) 112-119
25. Desfaits A.C., Serri O., and Renier G. Gliclazide decreases cell-mediated low-density lipoprotein (LDL) oxidation and reduces monocyte adhesion to endothelial cells induced by oxidatively modified LDL. Metabolism 46 (1997) 1150-1156
26. Scott N.A., Jennings P.E., Brown J., et al. Gliclazide: a general free radical scavenger. Eur J Pharmacology-Mol Pharmacol Section 208 (1991) 175-177
27. Desfaits A.C., Serri O., and Renier G. Normalization of plasma lipid peroxides, monocyte adhesion, and tumor necrosis factor-a production in NIDDM patients after gliclazide treatment. Diabetes Care 21 (1998) 487-493
28. Noda Y., Mori A., Cossins E., et al. Gliclazide scavenges hydroxyl and superoxide radicals: an electron spin resonance study. Metabolism 49 Suppl 1 (2000) 14-16
29. Satoh J., Takahashi K., Takizawa Y., et al. Secondary sulfonylurea failure: comparison of period until insulin treatment between diabetic patients treated with gliclazide and glibenclamide. Diabetes Res Clin Pract 70 (2005) 291-297