Differential selectivity of insulin secretagogues: Mechanisms, clinical implications, and drug interactions

Journal of Diabetes and its Complications

Volumn 17, Issue 2 SUPPL., 2003, Pages 11-15

  Gribble, Fiona M ^a   Reimann, Frank ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

ATP sensitive potassium channel (KATP channel); Sulphonylurea; Sulphonylurea receptor

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANTIANGINA PECTORIS AGENT; GLIBENCLAMIDE; GLICLAZIDE; GLIMEPIRIDE; INSULIN; MEGLITINIDE; NICORANDIL; NUCLEOTIDE; PINACIDIL; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL STIMULATING AGENT; RECEPTOR SUBUNIT; REPAGLINIDE; SULFONYLUREA DERIVATIVE; SULFONYLUREA RECEPTOR; TOLBUTAMIDE;

CONFERENCE PAPER; DRUG BINDING SITE; DRUG MECHANISM; DRUG POTENCY; DRUG SELECTIVITY; DRUG SENSITIVITY; DRUG TARGETING; HEART MUSCLE; IC 50; INSULIN RELEASE; ISCHEMIA; MOLECULAR CLONING; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OOCYTE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; TISSUE SPECIFICITY; VASCULAR SMOOTH MUSCLE; XENOPUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; DIABETES MELLITUS, TYPE 2; DRUG INTERACTIONS; HUMANS; INSULIN; ION CHANNEL GATING; ISLETS OF LANGERHANS; ORGAN SPECIFICITY; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN CONFORMATION; PROTEIN SUBUNITS; RECEPTORS, DRUG; SULFONYLUREA COMPOUNDS; XENOPUS;

EID: 0037338257     PISSN: 10568727     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8727(02)00272-6     Document Type: Conference Paper

References (36)

1. Aguilar-Bryan L., Nichols C.G., Wechsler S.W., Clement J.P., Boyd A.E., Gonzalez G., Herrera-Sosa H., Nguy K., Bryan J., Nelson D.A. Cloning of the beta-cell high-affinity sulphonylurea receptor: a regulator of insulin secretion. Science. 268:1995;423-425.
2. + channels and insulin secretion: their role in health and disease. Diabetologia. 42:1999;903-919.
3. Ashcroft F.M., Rorsman P. Electrophysiology of the pancreatic beta-cell. Progress in Biophysics and Molecular Biology. 54:1989;87-143.
4. ATP channel. Diabetes. 48:1999;1341-1347.
5. ATP channel isoforms are required for selective interaction with K′ channel openers. Journal of Biological Chemistry. 275:2000;717-720.
6. Bijlstra P.J., Lutterman J.A., Russel F.G.M., Thien T., Smits P. Interaction of sulphonylurea derivatives with vascular ATP-sensitive potassium channels in humans. Diabetologia. 39:1996;1083-1090.
7. Cogolludo A.L., Perez-Vizcaino F., Fajardo S., Ibarra M., Tamargo J. Effects of nicorandil as compared to mixtures of sodium nitroprusside and levcromakalim in isolated rat aorta. British Journal of Pharmacology. 126:1999;1025-1033.
8. Conti L.R., Radeke C.M., Shyng S.L., Vandenberg C.A. Transmembrane topology of the sulfonylurea receptor SUR1. Journal of Biological Chemistry. 276:2001;41270-41278.
9. Dabrowski M., Wahl P., Holmes W.E., Ashcroft F.M. Effect of repaglinide on cloned beta cell, cardiac and smooth muscle types of ATP-sensitive potassium channel. Diabetologia. 44:2001;747-756.
10. Gribble F.M., Ashcroft F.M. Differential sensitivity of β-cell and extrapancreatic KATP channels to gliclazide. Diabetologia. 42:1999;845-848.
11. Gribble F.M., Tucker S.J., Ashcroft F.M. The interaction of nucleotides with the tolbutamide block of K-ATP currents: a reinterpretation. Journal of Physiology. 504:1997;35-45.
12. ATP channels. Diabetes. 47:1998;1412-1418.
13. ATP channel. Biochemical and Biophysical Research Communications. 257:1999;766-770.
14. Hambrock A., Löffler-Walz C., Russ U., Lange U., Quast U. Characterization of a mutant sulfonylurea receptor SUR2B with high affinity for sulfonylureas and openers: differences in the coupling to Kir6.x subtypes. Molecular Pharmacology. 60:2001;190-199.
15. Hata N., Takano M., Kunimi H., Takano T. Lack of antagonism between nicorandil and sulfonylurea in stable angina pectoris. International Journal of Clinical Pharmacology Research. 21:2001;59-63.
16. ATP - an inward rectifier subunit plus the sulfonylurea receptor. Science. 270:1995;1166-1170.
17. + channels. Neuron. 16:1996;1011-1017.
18. Inagaki N., Tsuura Y., Namba N., Masuda K., Gonoi T., Horie M., Seino Y., Mizuta M., Seino S. Cloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heart. Journal of Biological Chemistry. 270:1995;5691-5694.
19. + channel. Journal of Biological Chemistry. 271:1996;24321-24325.
20. ATP channels. Functional coupling of Kir6.2 and SUR1 subunits. Journal of General Physiology. 114:1999;203-213.
21. ATP channels in mouse isolated pancreatic β-cells but not rat heart or arterial smooth muscle cells. Diabetologia. 44:2001;1019-1025.
22. Mikhailov M.V., Mikhailova E.A., Ashcroft S.J.H. Molecular structure of the glibenclamide binding site of the beta-cell K-ATP channel. FEBS Letters. 499:2001;154-160.
23. Morcau C., Jacquet H., Prost A.L., D'hahan N., Vivaudou M. The molecular basis of the specificity of action of K-ATP channel openers. EMBO Journal. 19:2000;6644-6651.
24. Nichols C.G., Lederer W.J. Adenosine triphosphate-sensitive potassium channels in the cardiovascular system. American Journal of Physiology. 261:1991;H1675-H1686.
25. Proks P., Reimann F., Green N., Gribble F.M., Ashcroft F.M. Sulphonylurea stimulation of insulin secretion. Diabetes. 51(Suppl. 3):2002;S368-S376.
26. Quayle J.M., Nelson M.T., Standen N.B. ATP-sensitive and inwardly rectifying potassium channels in smooth muscle. Physiological Reviews. 77:1997;1165-1232.
27. Reimann F., Ashcroft F.M., Gribble F.M. Structural basis for the interference between nicorandil and sulfonylurea action. Diabetes. 50:2001;2253-2259.
28. ATP channels by Mg-nucleotides. Journal of Physiology.
29. Reimann F., Proks P., Ashcroft F.M. Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel. British Journal of Pharmacology. 132:2001;1542-1548.
30. Sakura H., Ämmälä C., Smith P.A., Gribble F.M., Ashcroft F.M. Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle. FEBS Letters. 377:1995;338-344.
31. Song D.K., Ashcroft F.M. Glimepiride block of cloned β-cell, cardiac and smooth muscle K-ATP channels. British Journal of Pharmacology. 133:2001;193-199.
32. + channels and insulin secretion: comparison with the sulfonylureas and nateglinide. European Journal of Pharmacology. 431:2001;119-125.
33. Tusnady G.E., Bakos E., Varadi A., Sarkadi B. Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters. FEBS Letters. 402:1997;1-3.
34. Uhde I., Toman A., Gross I., Schwanstecher C., Schwanstecher M. Identification of the potassium channel opener site on sulfonylurea receptors. Journal of Biological Chemistry. 274:1999;28079-28082.
35. + channel. Journal of Physiology. 499:1997;715-720.
36. + channels from pancreatic β-cells. FEBS Letters. 239:1988;241-244.