Deletion of PTH rescues skeletal abnormalities and high osteopontin levels in Klotho-/- mice

PLoS Genetics

Volumn 8, Issue 5, 2012, Pages

  Yuan, Quan ^a,b   Sato, Tadatoshi ^a   Densmore, Michael ^a   Saito, Hiroaki ^a   Schüler, Christiane ^c   Erben, Reinhold G ^c   Lanske, Beate ^a  

^a HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

^b SICHUAN UNIVERSITY   (China)

^c UNIVERSITY OF VETERINARY MEDICINE   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; FIBROBLAST GROWTH FACTOR 23; KLOTHO PROTEIN; OSTEOPONTIN; PARATHYROID HORMONE; PHOSPHATE; VITAMIN D; BETA GLUCURONIDASE; FIBROBLAST GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DISEASE; BONE LEVEL; BONE MASS; BONE MINERALIZATION; BONE TURNOVER; CALCIUM BLOOD LEVEL; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; OSTEOMALACIA; PHOSPHATE BLOOD LEVEL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; VITAMIN BLOOD LEVEL; ANIMAL; BLOOD; BONE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; OSTEOBLAST; TRANSGENIC MOUSE;

MUS;

ANIMALS; BONE AND BONES; CALCIFICATION, PHYSIOLOGIC; CALCIUM; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; GLUCURONIDASE; MICE; MICE, TRANSGENIC; OSTEOBLASTS; OSTEOMALACIA; OSTEOPONTIN; PARATHYROID HORMONE; PHOSPHATES; VITAMIN D;

EID: 84863638352     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002726     Document Type: Article

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