Inactivation of klotho function induces hyperphosphatemia even in presence of high serum fibroblast growth factor 23 levels in a genetically engineered hypophosphatemic (Hyp) mouse model

FASEB Journal

Volumn 23, Issue 11, 2009, Pages 3702-3711

  Nakatani, Teruyo ^a   Ohnishi, Mutsuko ^a   Razzaque, M Shawkat ^a  

^a HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

Calcification; Kidney; NaPi2a; Parathyroid hormone; Survival; Vitamin D

Indexed keywords

CALCITRIOL; FIBROBLAST GROWTH FACTOR 23; KLOTHO PROTEIN; PARATHYROID HORMONE; PARATHYROID HORMONE[1-34]; PHOSPHATE; SODIUM PHOSPHATE COTRANSPORTER 2A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL CALCIFICATION; BLOOD VESSEL WALL; CONTROLLED STUDY; DISEASE SEVERITY; DOWN REGULATION; FEMALE; HYPERPHOSPHATEMIA; MALE; MOUSE; NONHUMAN; PARATHYROID HORMONE BLOOD LEVEL; PHENOTYPE; PHOSPHATE BLOOD LEVEL; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SOFT TISSUE CALCIFICATION; SURVIVAL; TRANSGENIC MOUSE; VITAMIN BLOOD LEVEL;

MUS;

ANIMALS; CALCIUM; FIBROBLAST GROWTH FACTORS; GLUCURONIDASE; HYPOPHOSPHATEMIA; MICE; MICE, KNOCKOUT; PHEX PHOSPHATE REGULATING NEUTRAL ENDOPEPTIDASE; PHOSPHATES; SODIUM-PHOSPHATE COTRANSPORTER PROTEINS, TYPE IIA; VITAMIN D;

EID: 70350552306     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-123992     Document Type: Article

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