Regulation of cementoblast gene expression by inorganic phosphate in vitro

Calcified Tissue International

Volumn 78, Issue 2, 2006, Pages 103-112

  Foster, B L ^a   Nociti Jr , F H ^a,b   Swanson, E C ^a   Matsa Dunn, D ^a   Berry, J E ^c   Cupp, C J ^d   Zhang, P ^d   Somerman, M J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF CAMPINAS   (Brazil)

^c UNIVERSITY OF MICHIGAN   (United States)

^d NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

Cementoblast; Osteopontin; Phosphate; Pyrophosphate; SIBLING gene

Indexed keywords

ALKALINE PHOSPHATASE; CELL MEMBRANE PROTEIN; COLLAGEN TYPE 1; DENTIN MATRIX PROTEIN 1; FOSCARNET; OSTEOCALCIN; OSTEOPONTIN; PHOSPHATE; PROTEIN; SIALOPROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASSAY; CELL COUNT; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; DENTIN; DOSE RESPONSE; DOWN REGULATION; GENE; GENE CONTROL; GENE EXPRESSION; HOMEOSTASIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; UPREGULATION;

EID: 32444450488     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-005-0184-7     Document Type: Article

References (52)

1. Nociti FH Jr, Berry JE, Foster BL, Gurley KA, Kingsley DM, Takata T, Miyauchi M, Somerman MJ (2002) Cementum: a phosphate-sensitive tissue. J Dent Res 81: 817-821
2. Ho AM, Johnson MD, Kingsley DM (2000) Role of the mouse ank gene in control of tissue calcification and arthritis. Science 289:265-270
3. Sweet HO, Green MC (1981) Progressive ankylosis, a new skeletal mutation in the mouse. J Hered 72:87-93
4. Hakim FT, Cranley R, Brown KS, Eanes ED, Harne L, Oppenheim JJ (1984) Hereditary joint disorder in progressive ankylosis (ank/ank) mice. I. Association of calcium hydroxyapatite deposition with inflammatory arthropathy. Arthritis Rheum 27:1411-1420
5. Sakamoto M, Hosoda Y, Kojimahara K, Yamazaki T, Yoshimura Y (1994) Arthritis and ankylosis in twy mice with hereditary multiple osteochondral lesions: with special reference to calcium deposition. Pathol Int 44:420-427
6. Okawa A, Nakamura I, Goto S, Moriya H, Nakamura Y, Ikegawa S (1998) Mutation in Npps in a mouse model of ossification of the posterior longitudinal ligament of the spine. Nat Genet 19:271-273
7. Hessle L, Johnson KA, Anderson HC, Narisawa S, Sali A, Goding JW, Terkeltaub R, Millan JL (2002) Tissue-nonspecific alkaline phosphatase and plasma cell membrane glycoprotein-1 are central antagonistic regulators of bone mineralization. Proc Natl Acad Sci USA 99:9445-9449
8. Whyte MP (2002) Hypophosphatasia: nature's window to alkaline phosphatase in man. In: Bilezikian JP, Raisz LG, Rodan G. (eds), Principles of bone biology. Academic Press, San Diego, pp 1229-1248
9. Whyte MP (1994) Hypophosphatasia and the role of alkaline phosphatase in skeletal mineralization. Endocr Rev 15:439-461
10. Tesch W, Vandenbos T, Roschgr P, Fratzl-Zelman N, Klaushofer K, Beertsen W, Fratzl P (2003) Orientation of mineral crystallites and mineral density during skeletal development in mice deficient in tissue nonspecific alkaline phosphatase. J Bone Miner Res 18:117-125
11. Girschick HJ, Seyberth HW, Huppertz HI (1999) Treatment of childhood hypophosphatasia with nonsteroidal antiinflammatory drugs. Bone 25:603-607
12. Beertsen W, Van den Bos T, Everts V (1999) Root development in mice lacking functional tissue non-specific alkaline phosphatase gene: inhibition of acellular cementum formation. J Dent Res 78:1221-1229
13. Henthorn PS, Raducha M, Fedde KN, Lafferty MA, Whyte MP (1992) Different missense mutations at the tissue-nonspecific alkaline phosphatase gene locus in autosomal recessively inherited forms of mild and severe hypophosphatasia. Proc Natl Acad Sci USA 89:9924-9928
14. Beck GR Jr, Knecht N (2003) Osteopontin regulation by inorganic phosphate is ERK1/2-, protein kinase C-, and proteasome-dependent. J Biol Chem 278:41921-41929
15. Harmey D, Hessle L, Narisawa S, Johnson KA, Terkeltaub R, Millan JL (2004) Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders. Am J Pathol 164:1199-1209
16. D'Errico JA, Berry JE, Ouyang H, Strayhorn CL, Windle JJ, Somerman MJ (2000) Employing a transgenic animal model to obtain cementoblasts in vitro. J Periodontol 71:63-72
17. Meleti Z, Shapiro IM, Adams CS (2000) Inorganic phosphate induces apoptosis of osteoblast-like cells in culture. Bone 27:359-366
18. Beck GR Jr, Moran E, Knecht N (2003) Inorganic phosphate regulates multiple genes during osteoblast differentiation, including Nrf2. Exp Cell Res 288:288-300
19. Wang D, Christensen K, Chawla K, Xiao G, Krebsbach PH, Franceschi RT (1999) Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential. J Bone Miner Res 14:893-903
20. Fisher LW, Fedarko NS (2003) Six genes expressed in bones and teeth encode the current members of the SIBLING family of proteins. Connect Tissue Res 44(suppl 1):33-40
21. Qin C, Baba O, Butler WT (2004) Post-translational modifications of sibling proteins and their roles in osteogenesis and dentinogenesis. Crit Rev Oral Biol Med 15:126-136
22. Huq NL, Cross KJ, Ung M, Reynolds EC (2005) A review of protein structure and gene organisation for proteins associated with mineralised tissue and calcium phosphate stabilisation encoded on human chromosome 4. Arch Oral Biol 50:599-609
23. Jain A, Karadag A, Fohr B, Fisher LW, Fedarko NS (2002) Three SIBLINGs (small integrin-binding ligand, N-linked glycoproteins) enhance factor H's cofactor activity enabling MCP-like cellular evasion of complement-mediated attack. J Biol Chem 277:13700-13708
24. Fedarko NS, Jain A, Karadag A, Fisher LW (2004) Three small integrin binding ligand N-linked glycoproteins (SIBLINGs) bind and activate specific matrix metalloproteinases. FASEB J 18:734-736
25. Kaartinen MT, Sun W, Kaipatur N, McKee MD (2005) Transglutaminase crosslinking of SIBLING proteins in teeth. J Dent Res 84:607-612
26. Boskey AL, Maresca M, Ullrich W, Doty SB, Butler WT, Prince CW (1993) Osteopontin-hydroxyapatite interactions in vitro: inhibition of hydroxyapatite formation and growth in a gelatin-gel. Bone Miner 22:147-159
27. Harris NL, Rattray KR, Tye CE, Underhill TM, Somerman MJ, D'Errico JA, Chambers AF, Hunter GK, Goldberg HA (2000) Functional analysis of bone sialoprotein: identification of the hydroxyapatite-nucleating and cell-binding domains by recombinant peptide expression and site-directed mutagenesis. Bone 27:795-802
28. He G, Dahl T, Veis A, George A (2003) Dentin matrix protein 1 initiates hydroxyapatite formation in vitro. Connect Tissue Res 44(suppl 1):240-245
29. Baba O, Qin C, Brunn JC, Wygant JN, McIntyre BW, Butler WT (2004) Colocalization of dentin matrix protein 1 and dentin sialoprotein at late stages of rat molar development. Matrix Biol 23:371-379
30. Ye L, MacDougall M, Zhang S, Xie Y, Zhang J, Li Z, Lu Y, Mishina Y, Feng JQ (2004) Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development. J Biol Chem 279:19141-19148
31. Ye L, Mishina Y, Chen D, Huang H, Dallas SL, Dallas MR, Sivakumar P, Kunieda T, Tsutsui TW, Boskey A, Bonewald LF, Feng JQ (2005) Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype. J Biol Chem 280: 6197-6203
32. Takano Y, Sakai H, Watanabe E, Ideguchi-Ohma N, Jayawardena CK, Arai K, Asawa Y, Nakano Y, Shuda Y, Sakamoto Y, Terashima T (2003) Possible role of dentin matrix in region-specific deposition of cellular and acellular extrinsic fibre cementum. J Electron Microsc (Tokyo) 52:573-580
33. Johnson KA, Hessle L, Vaingankar S, Wennberg C, Mauro S, Narisawa S, Goding JW, Sano K, Millan JL, Terkeltaub R (2000) Osteoblast tissue-nonspecific alkaline phosphatase antagonizes and regulates PC-1. Am J Physiol Regul Integr Comp Physiol 279:R1365-R1377
34. i and osteopontin mediate pathologic calcification associated with defective PC-1 and ANK expression. J Bone Miner Res 18:994-1004
35. Nielsen LB, Pedersen FS, Pedersen L (2001) Expression of type III sodium-dependent phosphate transporters/retroviral receptors mRNAs during osteoblast differentiation. Bone 28:160-166
36. Murshed M, Harmey D, Millan JL, McKee MD, Karsenty G (2005) Unique coexpression in osteoblasts of broadly expressed genes accounts for the spatial restriction of ECM mineralization to bone. Genes Dev 19:1093-1104
37. Zhao M, Berry JE, Somerman MJ (2003) Bone morphogenetic protein-2 inhibits differentiation and mineralization of cementoblasts in vitro. J Dent Res 82:23-27
38. Goziotis A, Sukhu B, Torontali M, Dowhaniuk M, Tenenbaum HC (1995) Effects of bisphosphonates APD and HEBP on bone metabolism in vitro. Bone 16:317S-327S
39. D'Aoust P, McCulloch CA, Tenenbaum HC, Lekic PC (2000) Etidronate (HEBP) promotes osteoblast differentiation and wound closure in rat calvaria. Cell Tissue Res 302:353-363
40. Chun YH, Foster BL, Lukasavage PA, Berry JE, Zhao M, Tenenbaum H, Somerman M (2005) Bisphosphonate modulates cementoblast behavior in vitro. J Periodontol 76:1890-1900
41. Terkeltaub RA (2001) Inorganic pyrophosphate generation and disposition in pathophysiology. Am J Physiol Cell Physiol 281:C1-C11
42. Beck GR Jr, Zerler B, Moran E (2000) Phosphate is a specific signal for induction of osteopontin gene expression. Proc Natl Acad Sci USA 97:8352-8357
43. Beck GR Jr (2003) Inorganic phosphate as a signaling molecule in osteoblast differentiation. J Cell Biochem 90:234-243
44. Zhao M, Xiao G, Berry JE, Franceschi RT, Reddi A, Somerman MJ (2002) Bone morphogenetic protein 2 induces dental follicle cells to differentiate toward a cementoblast/osteoblast phenotype. J Bone Miner Res 18:1441-1451
45. Mansfield K, Rajpurohit R, Shapiro IM (1999) Extracellular phosphate ions cause apoptosis of terminally differentiated epiphyseal chondrocytes. J Cell Physiol 179: 276-286
46. Bosshardt DD (2005) Are cementoblasts a subpopulation of osteoblasts or a unique phenotype? J Dent Res 84: 390-406
47. MacNeil RL, D'Errico JA, Ouyang H, Berry J, Strayhorn C Somerman MJ (1998) Isolation of murine cementoblasts: unique cells or uniquely-positioned osteoblasts? Eur J Oral Sci 106(suppl 1):350-356
48. Boabaid F, Berry JE, Koh AJ, Somerman MJ, McCauley LK (2004) The role of parathyroid hormone-related protein in the regulation of osteoclastogenesis by cementoblasts. J Periodontol 75:1247-1254
49. Nociti FH Jr, Foster BL, Barros SP, Darveau RP, Somerman MJ (2004) Cementoblast gene expression is regulated by Porphyromonas gingivalis lipopolysaccharide partially via toll-like receptor-4/MD-2. J Dent Res 83:602-607
50. 2+ store. J Biol Chem 278:17500-17508
51. Mansfield K, Pucci B, Adams CS, Shapiro IM (2003) Induction of apoptosis in skeletal tissues: phosphate-mediated chick chondrocyte apoptosis is calcium dependent. Calcif Tissue Int 73:161-172
52. Adams CS, Mansfield K, Perlot RL, Shapiro IM (2001) Matrix regulation of skeletal cell apoptosis. Role of calcium and phosphate ions. J Biol Chem 276:20316-20322