-
1
-
-
0017032590
-
Hypophosphatemia: Mouse model for human familial hypophosphatemic (vitamin D-resistant) rickets
-
Eicher EM, Southard JL, Scriver CR, Glorieux FH 1976 Hypophosphatemia: mouse model for human familial hypophosphatemic (vitamin D-resistant) rickets. Proc Natl Acad Sci USA 73:4667-4671
-
(1976)
Proc Natl Acad Sci USA
, vol.73
, pp. 4667-4671
-
-
Eicher, E.M.1
Southard, J.L.2
Scriver, C.R.3
Glorieux, F.H.4
-
2
-
-
0030615069
-
Pex gene deletions in Gy and Hyp mice provide mouse models for X-linked hypophosphatemia
-
Strom TM, Francis F, Lorenz B, Böddrich A, Econs MJ, Lehrach H, Meitinger T 1997 Pex gene deletions in Gy and Hyp mice provide mouse models for X-linked hypophosphatemia. Hum Mol Genet 6:165-171
-
(1997)
Hum Mol Genet
, vol.6
, pp. 165-171
-
-
Strom, T.M.1
Francis, F.2
Lorenz, B.3
Böddrich, A.4
Econs, M.J.5
Lehrach, H.6
Meitinger, T.7
-
3
-
-
0030938927
-
Pex/PEX tissue distribution and evidence for a deletion in the 3′ region of the Pex gene in X-linked hypophosphatemic mice
-
Beck L, Soumounou Y, Martel J, Krishnamurthy G, Gauthier C, Goodyer CG, Tenenhouse HS 1997 Pex/PEX tissue distribution and evidence for a deletion in the 3′ region of the Pex gene in X-linked hypophosphatemic mice. J Clin Invest 99:1200-1209
-
(1997)
J Clin Invest
, vol.99
, pp. 1200-1209
-
-
Beck, L.1
Soumounou, Y.2
Martel, J.3
Krishnamurthy, G.4
Gauthier, C.5
Goodyer, C.G.6
Tenenhouse, H.S.7
-
4
-
-
0029160578
-
-
The HYP Consortium 1995 A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. Nat Genet 11:130-136
-
The HYP Consortium 1995 A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. Nat Genet 11:130-136
-
-
-
-
5
-
-
0035932945
-
FGF23, hypophosphatemia, and rickets: Has phosphatonin been found?
-
Strewler GJ 2001 FGF23, hypophosphatemia, and rickets: has phosphatonin been found? Proc Natl Acad Sci USA 98:5945-5946
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 5945-5946
-
-
Strewler, G.J.1
-
6
-
-
0013118819
-
The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency
-
Bai XY, Miao D, Goltzman D, Karaplis AC 2003 The autosomal dominant hypophosphatemic rickets R176Q mutation in fibroblast growth factor 23 resists proteolytic cleavage and enhances in vivo biological potency. J Biol Chem 278:9843-9849
-
(2003)
J Biol Chem
, vol.278
, pp. 9843-9849
-
-
Bai, X.Y.1
Miao, D.2
Goltzman, D.3
Karaplis, A.C.4
-
7
-
-
0033847087
-
Tumor-induced osteomalacia and the regulation of phosphate homeostasis
-
Kumar R 2000 Tumor-induced osteomalacia and the regulation of phosphate homeostasis. Bone 27:333-338
-
(2000)
Bone
, vol.27
, pp. 333-338
-
-
Kumar, R.1
-
8
-
-
33845631059
-
Klotho converts canonical FGF receptor into a specific receptor for FGF23
-
Urakawa I, Yamazaki Y, Shimada T, Iijima K, Hasegawa H, Okawa K, Fujita T, Fukumoto S, Yamashita T 2006 Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature 444:770-774
-
(2006)
Nature
, vol.444
, pp. 770-774
-
-
Urakawa, I.1
Yamazaki, Y.2
Shimada, T.3
Iijima, K.4
Hasegawa, H.5
Okawa, K.6
Fujita, T.7
Fukumoto, S.8
Yamashita, T.9
-
9
-
-
0032489424
-
Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein
-
Shiraki-Iida T, Aizawa H, Matsumura Y, Sekine S, Iida A, Anazawa H, Nagai R, Kuro-o M, Nabeshima Y 1998 Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein. FEBS Lett 424:6-10
-
(1998)
FEBS Lett
, vol.424
, pp. 6-10
-
-
Shiraki-Iida, T.1
Aizawa, H.2
Matsumura, Y.3
Sekine, S.4
Iida, A.5
Anazawa, H.6
Nagai, R.7
Kuro-o, M.8
Nabeshima, Y.9
-
10
-
-
0032567647
-
Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein
-
Matsumura Y, Aizawa H, Shiraki-Iida T, Nagai R, Kuro-o M, Nabeshima Y 1998 Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein. Biochem Biophys Res Commun 242:626-630
-
(1998)
Biochem Biophys Res Commun
, vol.242
, pp. 626-630
-
-
Matsumura, Y.1
Aizawa, H.2
Shiraki-Iida, T.3
Nagai, R.4
Kuro-o, M.5
Nabeshima, Y.6
-
11
-
-
0030724491
-
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
-
Kuro-o M, Matsumura Y, Aizawa H, Kawaguchi H, Suga T, Utsugi T, Ohyama Y, Kurabayashi M, Kaname T, Kume E, Iwasaki H, Iida A, Shiraki-Iida T, Nishikawa S, Nagai R, Nabeshima YI 1997 Mutation of the mouse klotho gene leads to a syndrome resembling ageing. Nature 390:45-51
-
(1997)
Nature
, vol.390
, pp. 45-51
-
-
Kuro-o, M.1
Matsumura, Y.2
Aizawa, H.3
Kawaguchi, H.4
Suga, T.5
Utsugi, T.6
Ohyama, Y.7
Kurabayashi, M.8
Kaname, T.9
Kume, E.10
Iwasaki, H.11
Iida, A.12
Shiraki-Iida, T.13
Nishikawa, S.14
Nagai, R.15
Nabeshima, Y.I.16
-
12
-
-
33646578195
-
Regulation of fibroblast growth factor-23 signaling by klotho
-
Kurosu H, Ogawa Y, Miyoshi M, Yamamoto M, Nandi A, Rosenblatt KP, Baum MG, Schiavi S, Hu MC, Moe OW, Kuro-oM 2006 Regulation of fibroblast growth factor-23 signaling by klotho. J Biol Chem 281:6120-6123
-
(2006)
J Biol Chem
, vol.281
, pp. 6120-6123
-
-
Kurosu, H.1
Ogawa, Y.2
Miyoshi, M.3
Yamamoto, M.4
Nandi, A.5
Rosenblatt, K.P.6
Baum, M.G.7
Schiavi, S.8
Hu, M.C.9
Moe, O.W.10
oM, K.11
-
13
-
-
0026603529
-
Development and validation of a radioimmunoassay for mouse osteocalcin: Paradoxical response in the Hyp mouse
-
Gundberg CM, Clough ME, Carpenter TO 1992 Development and validation of a radioimmunoassay for mouse osteocalcin: paradoxical response in the Hyp mouse. Endocrinology 130:1909-1915
-
(1992)
Endocrinology
, vol.130
, pp. 1909-1915
-
-
Gundberg, C.M.1
Clough, M.E.2
Carpenter, T.O.3
-
14
-
-
0023488581
-
Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
-
Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR 1987 Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2:595-610
-
(1987)
J Bone Miner Res
, vol.2
, pp. 595-610
-
-
Parfitt, A.M.1
Drezner, M.K.2
Glorieux, F.H.3
Kanis, J.A.4
Malluche, H.5
Meunier, P.J.6
Ott, S.M.7
Recker, R.R.8
-
15
-
-
0036150953
-
Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1 α-hydroxylase gene
-
Yoshida T, Fujimori T, Nabeshima Y 2002 Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1 α-hydroxylase gene. Endocrinology 143:683-689
-
(2002)
Endocrinology
, vol.143
, pp. 683-689
-
-
Yoshida, T.1
Fujimori, T.2
Nabeshima, Y.3
-
17
-
-
0023281635
-
Evidence that low plasma 1,25-dihydroxyvitamin D causes intestinal malabsorption of calcium and phosphate in juvenile X-linked hypophosphatemic mice
-
Meyer Jr RA, Meyer MH, Gray RW, Bruns ME 1987 Evidence that low plasma 1,25-dihydroxyvitamin D causes intestinal malabsorption of calcium and phosphate in juvenile X-linked hypophosphatemic mice. J Bone Miner Res 2:67-82
-
(1987)
J Bone Miner Res
, vol.2
, pp. 67-82
-
-
Meyer Jr, R.A.1
Meyer, M.H.2
Gray, R.W.3
Bruns, M.E.4
-
19
-
-
34047260591
-
FGF23 is a hormone-regulating phosphate metabolism: Unique biological characteristics of FGF23
-
Fukumoto S, Yamashita T 2007 FGF23 is a hormone-regulating phosphate metabolism: unique biological characteristics of FGF23. Bone 40:1190-1195
-
(2007)
Bone
, vol.40
, pp. 1190-1195
-
-
Fukumoto, S.1
Yamashita, T.2
-
20
-
-
0242497210
-
Differential effects of Npt2a gene ablation and X-linked Hyp mutation on renal expression of Npt2c
-
Tenenhouse HS, Martel J, Gauthier C, Segawa H, Miyamoto K 2003 Differential effects of Npt2a gene ablation and X-linked Hyp mutation on renal expression of Npt2c. Am J Physiol Renal Physiol 285:F1271-F1278
-
(2003)
Am J Physiol Renal Physiol
, vol.285
-
-
Tenenhouse, H.S.1
Martel, J.2
Gauthier, C.3
Segawa, H.4
Miyamoto, K.5
-
21
-
-
3242656464
-
FGF23 is processed by proprotein convertases but not by PHEX
-
Benet-Pagès A, Lorenz-Depiereux B, Zischka H, White KE, Econs MJ, Strom TM 2004 FGF23 is processed by proprotein convertases but not by PHEX. Bone 35:455-462
-
(2004)
Bone
, vol.35
, pp. 455-462
-
-
Benet-Pagès, A.1
Lorenz-Depiereux, B.2
Zischka, H.3
White, K.E.4
Econs, M.J.5
Strom, T.M.6
-
22
-
-
33745850756
-
Pathogenic role of Fgf23 in Hyp mice
-
Liu S, Zhou J, Tang W, Jiang X, Rowe DW, Quarles LD 2006 Pathogenic role of Fgf23 in Hyp mice. Am J Physiol Endocrinol Metab 291:E38-E49
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
-
-
Liu, S.1
Zhou, J.2
Tang, W.3
Jiang, X.4
Rowe, D.W.5
Quarles, L.D.6
-
23
-
-
34250649644
-
The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasis
-
Razzaque MS, Lanske B 2007 The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasis. J Endocrinol 194:1-10
-
(2007)
J Endocrinol
, vol.194
, pp. 1-10
-
-
Razzaque, M.S.1
Lanske, B.2
-
24
-
-
0032746021
-
Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia
-
Kawaguchi H, Manabe N, Miyaura C, Chikuda H, Nakamura K, Kuro-o M 1999 Independent impairment of osteoblast and osteoclast differentiation in klotho mouse exhibiting low-turnover osteopenia. J Clin Invest 104:229-237
-
(1999)
J Clin Invest
, vol.104
, pp. 229-237
-
-
Kawaguchi, H.1
Manabe, N.2
Miyaura, C.3
Chikuda, H.4
Nakamura, K.5
Kuro-o, M.6
-
25
-
-
24944481544
-
Suppression of aging in mice by the hormone Klotho
-
Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, McGuinness OP, Chikuda H, Yamaguchi M, Kawaguchi H, Shimomura I, Takayama Y, Herz J, Kahn CR, Rosenblatt KP, Kuro-o M 2005 Suppression of aging in mice by the hormone Klotho. Science 309:1829-1833
-
(2005)
Science
, vol.309
, pp. 1829-1833
-
-
Kurosu, H.1
Yamamoto, M.2
Clark, J.D.3
Pastor, J.V.4
Nandi, A.5
Gurnani, P.6
McGuinness, O.P.7
Chikuda, H.8
Yamaguchi, M.9
Kawaguchi, H.10
Shimomura, I.11
Takayama, Y.12
Herz, J.13
Kahn, C.R.14
Rosenblatt, K.P.15
Kuro-o, M.16
-
26
-
-
36049037977
-
Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1 α-hydroxylase expression in vitro
-
Perwad F, Zhang MY, Tenenhouse HS, Portale AA 2007 Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1 α-hydroxylase expression in vitro. Am J Physiol Renal Physiol 293:F1577-F1583
-
(2007)
Am J Physiol Renal Physiol
, vol.293
-
-
Perwad, F.1
Zhang, M.Y.2
Tenenhouse, H.S.3
Portale, A.A.4
-
27
-
-
22244464849
-
Klotho protein activates the PKC pathway in the kidney and testis and suppresses 25-hydroxyvitamin D3 1 α-hydroxylase gene expression
-
Imai M, Ishikawa K, Matsukawa N, Kida I, Ohta J, Ikushima M, Chihara Y, Rui X, Rakugi H, Ogihara T 2004 Klotho protein activates the PKC pathway in the kidney and testis and suppresses 25-hydroxyvitamin D3 1 α-hydroxylase gene expression. Endocrine 25:229-234
-
(2004)
Endocrine
, vol.25
, pp. 229-234
-
-
Imai, M.1
Ishikawa, K.2
Matsukawa, N.3
Kida, I.4
Ohta, J.5
Ikushima, M.6
Chihara, Y.7
Rui, X.8
Rakugi, H.9
Ogihara, T.10
-
28
-
-
42149130855
-
A translocation causing increased α-klotho level results in hypophosphatemic rickets and hyperparathyroidism
-
Brownstein CA, Adler F, Nelson-Williams C, Iijima J, Li P, Imura A, Nabeshima Y, Reyes-Mugica M, Carpenter TO, Lifton RP 2008 A translocation causing increased α-klotho level results in hypophosphatemic rickets and hyperparathyroidism. Proc Natl Acad Sci USA 105:3455-3460
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3455-3460
-
-
Brownstein, C.A.1
Adler, F.2
Nelson-Williams, C.3
Iijima, J.4
Li, P.5
Imura, A.6
Nabeshima, Y.7
Reyes-Mugica, M.8
Carpenter, T.O.9
Lifton, R.P.10
|