Altitude training for elite endurance performance: A 2012 update

Current Sports Medicine Reports

Volumn 11, Issue 3, 2012, Pages 148-154

  Fudge, Barry W ^a   Pringle, Jamie S M ^a   Maxwell, Neil S ^b   Turner, Gareth ^a,b   Ingham, Stephen A ^a   Jones, Andrew M ^c  

^a LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BRIGHTON   (United Kingdom)

^c UNIVERSITY OF EXETER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN;

ADAPTATION; ALTITUDE; ATHLETE; ATHLETIC PERFORMANCE; BREATHING EXERCISE; ENDURANCE TRAINING; HUMAN; OXYGEN CONSUMPTION; REVIEW; SEA LEVEL; TECHNOLOGY;

ALTITUDE; ATHLETIC PERFORMANCE; HUMANS; PHYSICAL EDUCATION AND TRAINING; PHYSICAL ENDURANCE;

EID: 84863620780     PISSN: 1537890X     EISSN: 15378918     Source Type: Journal    
DOI: 10.1249/JSR.0b013e31825640d5     Document Type: Review

References (45)

1. Arcasoy MO. The non-haematopoietic biological effects of erythropoietin. Br. J. Haematol. 2008; 141:14-31. (Pubitemid 351347536)
2. Berglund B, Hemmingson P. Effect of reinfusion of autologous blood on exercise performance in cross-country skiers. Int. J. Sports Med. 1987; 8:231-3. (Pubitemid 17112540)
3. Bonetti DL, Hopkins WG. Sea-level exercise performance following adaptation to hypoxia: a meta-analysis. Sports Med. 2009; 39:107-27.
4. Brien AJ, Simon TL. The effects of red blood cell infusion on 10-km race time. JAMA. 1987; 257:2761-5. (Pubitemid 17066519)
5. 2 uptake and time to exhaustion during severe-intensity cycle exercise in humans. Exp. Physiol. 2006; 91:499-509.
6. Burtscher M, Gatterer H, Faulhaber M, Gerstgrasser W, Schenk K. Effects of intermittent hypoxia on running economy. Int. J. Sports Med. 2010; 31:644-50.
7. Chapman RF, Stager JM, Tanner DA, Stray-Gundersen J, Levine BD. Impairment of 3000-m run time at altitude is influenced by arterial oxyhemoglobin saturation. Med. Sci. Sports Exerc. 2011; 43:1649-56.
8. Chapman RF, Stray-Gundersen J, Levine BD. EPO production at altitude in elite endurance athletes is not associated with the sea level hypoxic ventilatory response. J. Sci. Med. Sport. 2010; 13:624-9.
9. Clark SA, Quod MJ, Clark MA, et al. Time course of haemoglobin mass during 21 days live high:train low simulated altitude. Eur. J. Appl. Physiol. 2009; 106:399-406.
10. 2max in adolescents. Eur. J. Appl. Physiol. 2009; 10:715-21.
11. Eastwood A, Sharpe K, Bourdon PC, et al. Within subject variation in hemoglobin mass in elite athletes. Med. Sci. Sports Exerc. 2012; 4:725-32.
12. Ekblom B. Blood doping and erythropoietin. The effects of variation in hemoglobin concentration and other related factors on physical performance. Am. J. Sports Med. 1996; 24(Suppl. 6):S40-2. (Pubitemid 26423204)
13. Ekblom B, Huot R. Response to submaximal and maximal exercise at different levels of carboxyhemoglobin. Acta Physiol. Scand. 1972; 86:474-82.
14. Frese F, Friedmann-Bette B. Effects of repetitive training at low altitude on erythropoiesis in 400 and 800 m runners. Int. J. Sports Med. 2010; 31:382-8.
15. Friedmann-bette B, Ulrich G, Ba P. Total haemoglobin mass and red blood cell profile in endurance-trained and non-endurance-trained adolescent athletes. Eur. J. Appl. Physiol. 2011; 111:497-507.
16. Garvican L, Martin D, Quod M, et al. Time course of the hemoglobin mass response to natural altitude training in elite endurance cyclists. Scand. J. Med. Sci. Sports. 2012; 22:95-103.
17. Garvican LA, Martin DT, McDonald W, Gore CJ. Seasonal variation of haemoglobin mass in internationally competitive female road cyclists. Eur. J. Appl. Physiol. 2010; 109:221-31.
18. Garvican LA, Pottgiesser T, Martin DT, et al. The contribution of haemoglobin mass to increases in cycling performance induced by simulated LHTL. Eur. J. Appl. Physiol. 2011; 111:1089-101.
19. Gore CJ, Hopkins WG. Counterpoint: positive effects of intermittent hypoxia (live high:train low) on exercise performance are not mediated primarily by augmented red cell volume. J. Appl. Physiol. 2005; 99:2055-7; discussion 2057-8. (Pubitemid 41547210)
20. Gough CE, Saunders PU, Fowlie J, et al. Influence of altitude training modality on performance and total haemoglobin mass in elite swimmers. Eur. J. Appl. Physiol. 2012 Jan 11.[Epub ahead of print].
21. Hinckson EA, Hopkins WG. Reliability of time to exhaustion analyzed with critical-power and log-log modeling. Med. Sci. Sports Exerc. 2005; 37:696-701. (Pubitemid 40478479)
22. Hopkins WG, Hewson DJ. Variability of competitive performance of distance runners. Med. Sci. Sports Exerc. 2001; 33:1588-92. (Pubitemid 32831450)
23. Kanstrup IL, Ekblom B. Blood volume and hemoglobin concentration as determinants of maximal aerobic power. Med. Sci. Sports Exerc. 1984; 16:256-62. (Pubitemid 14050568)
24. 2max decrement during exposure to acute hypoxia. J. Appl. Physiol. 1988; 64:1486-92.
25. Maassen N, Pries A. The hematocrit paradox - how does blood doping really work? Int. J. Sports Med. 2011; 32:242-6.
26. Millet GP, Roels B, Schmitt L, Woorons X, Richalet J-P. Combining hypoxic methods for peak performance. Sports Med. 2010; 40:1-25.
27. Miskowiak K, Inkster B, Selvaraj S, et al. Erythropoietin improves mood and modulates the cognitive and neural processing of emotion 3 days post administration. Neuropsychopharmacology. 2008; 33:611-8.
28. Ninot G, Connes P, Caillaud C. Effects of recombinant human erythropoietin injections on physical self in endurance athletes. J. Sports Sci. 2006; 24:383-91.
29. Nybo L, Secher NH. Cerebral perturbations provoked by prolonged exercise. Prog. Neurobiol. 2004; 72:223-61. (Pubitemid 38609579)
30. 2max. J. Appl. Physiol. 1989; 66:2491-5. (Pubitemid 19164939)
31. Rasmussen P, Foged EM, Nielsen J, et al. Effects of erythropoietin administration on cerebral metabolism and exercise capacity in men. J. Appl. Physiol. 2011; 109:476-83.
32. Rice L, Alfrey CP. The negative regulation of red cell mass by neocytolysis: physiologic and pathophysiologic manifestations. Cell. Physiol. Biochem. 2005; 77030:245-50. (Pubitemid 41022626)
33. Robertson EY, Aughey RJ, Anson JM, Hopkins WG, Pyne DB. Effects of simulated and real altitude exposure in elite swimmers. J. Strength Cond. Res. 2010; 24:487-93.
34. Robertson EY, Saunders PU, Pyne DB, et al. Reproducibility of performance changes to simulated live high/train low altitude. Med. Sci. Sports Exerc. 2010; 42:394-401.
35. Robertson EY, Saunders PU, Pyne DB, Gore CJ, Anson JM. Effectiveness of intermittent training in hypoxia combined with live high/train low. Eur. J. Appl. Physiol. 2010; 110:379-87.
36. Saunders PU, Pyne DB, Gore CJ. Endurance training at altitude. High Alt. Med. Biol. 2009; 10:135-48.
37. Schmidt W, Prommer N. The optimised CO-rebreathing method: a new tool to determine total haemoglobin mass routinely. Eur. J. Appl. Physiol. 2005; 95:486-95. (Pubitemid 41762554)
38. 2max. Exerc. Sport Sci. Rev. 2010; 38:68-75.
39. Schmutz S, Christoph D, Wittwer M, et al. A hypoxia complement differentiates the muscle response to endurance exercise. Exp. Physiol. 2010; 95:723-35.
40. Semenza GL. Regulation of oxygen homeostasis by hypoxia-inducible factor 1 knockout mice expression. Physiology. 2009; 24:97-106.
41. Siebenmann C, Robach P, Jacobs RA, et al. "Live high - train low" using normobaric hypoxia: a double-blinded, placebo-controlled study. J. Appl. Physiol. 2012; 112:106-17.
42. Steiner T, Wehrlin JP. Does hemoglobin mass increase from age 16 to 21 and 28 in elite endurance athletes? Med. Sci. Sports Exerc. 2011; 43:1735-43.
43. Wilber RL. Application of altitude/hypoxic training by elite athletes. Med. Sci. Sports Exerc. 2007; 39:1610-24. (Pubitemid 47360986)
44. Wilber RL. Introduction to altitude/hypoxic training symposium. Med. Sci. Sports Exerc. 2007; 39:1587-9. (Pubitemid 47360983)
45. 2 uptake kinetics during exercise in humans. J. Physiol. 2005; 568(Pt 2):639-52. (Pubitemid 41555463)