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Volumn 7, Issue 7, 2012, Pages

GIP-Overexpressing mice demonstrate reduced diet-induced obesity and steatosis, and improved glucose homeostasis

Author keywords

[No Author keywords available]

Indexed keywords

GASTRIC INHIBITORY POLYPEPTIDE; GLUCOSE;

EID: 84863615352     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0040156     Document Type: Article
Times cited : (146)

References (55)
  • 1
    • 0037371744 scopus 로고    scopus 로고
    • Pharmacological agents that directly modulate insulin secretion
    • Doyle M, Egan J, (2003) Pharmacological agents that directly modulate insulin secretion. Pharmacological Reviews 55: 105-131.
    • (2003) Pharmacological Reviews , vol.55 , pp. 105-131
    • Doyle, M.1    Egan, J.2
  • 2
    • 17044386953 scopus 로고    scopus 로고
    • Type 2 diabetes: principles of pathogenesis and therapy
    • Stumvoll M, Goldstein B, van Haeften T, (2005) Type 2 diabetes: principles of pathogenesis and therapy. Lancet 365: 1333-1346.
    • (2005) Lancet , vol.365 , pp. 1333-1346
    • Stumvoll, M.1    Goldstein, B.2    van Haeften, T.3
  • 3
    • 14644418458 scopus 로고    scopus 로고
    • A systematic review of drug therapy to delay or prevent type 2 diabetes
    • Padwal R, Majumda S, Johnson J, Varney J, McAlister F, (2005) A systematic review of drug therapy to delay or prevent type 2 diabetes. Diabetes Care 28: 736-744.
    • (2005) Diabetes Care , vol.28 , pp. 736-744
    • Padwal, R.1    Majumda, S.2    Johnson, J.3    Varney, J.4    McAlister, F.5
  • 5
    • 33845998516 scopus 로고    scopus 로고
    • The role of gut hormones in glucose homeostasis
    • Drucker DJ, (2007) The role of gut hormones in glucose homeostasis. J Clin Invest. 117: 24-32.
    • (2007) J Clin Invest , vol.117 , pp. 24-32
    • Drucker, D.J.1
  • 6
    • 35748957503 scopus 로고    scopus 로고
    • The physiology of glucagon-like peptide-1
    • Holst JJ, (2007) The physiology of glucagon-like peptide-1. Physiol. Rev. 87: 1409-1439.
    • (2007) Physiol. Rev. , vol.87 , pp. 1409-1439
    • Holst, J.J.1
  • 8
    • 2542479899 scopus 로고    scopus 로고
    • Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system
    • Brubaker PL, Drucker DJ, (2004) Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut, and central nervous system. Endocrinology 145: 2653-2659.
    • (2004) Endocrinology , vol.145 , pp. 2653-2659
    • Brubaker, P.L.1    Drucker, D.J.2
  • 9
    • 61349172037 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide (Gastric Inhibitory Polypeptide; GIP)
    • McIntosh CHS, Widenmaier S, Kim SJ, (2009) Glucose-dependent insulinotropic polypeptide (Gastric Inhibitory Polypeptide; GIP). Vitam Horm. 80: 409-471.
    • (2009) Vitam Horm , vol.80 , pp. 409-471
    • McIntosh, C.H.S.1    Widenmaier, S.2    Kim, S.J.3
  • 10
    • 0036317496 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV-resistant [D-Ala(2)]glucose-dependent insulinotropic polypeptide (GIP) improves glucose tolerance in normal and obese diabetic rats
    • Hinke SA, Gelling RW, Pederson RA, Manhart S, Nian C, et al. (2002) Dipeptidyl peptidase IV-resistant [D-Ala(2)]glucose-dependent insulinotropic polypeptide (GIP) improves glucose tolerance in normal and obese diabetic rats. Diabetes. 51: 652-61.
    • (2002) Diabetes , vol.51 , pp. 652-661
    • Hinke, S.A.1    Gelling, R.W.2    Pederson, R.A.3    Manhart, S.4    Nian, C.5
  • 11
    • 79951776754 scopus 로고    scopus 로고
    • Comparison of sub-chronic metabolic effects of stable forms of naturally occurring GIP(1-30) and GIP(1-42) in high-fat fed mice
    • Gault VA, Porter DW, Irwin N, Flatt PR, (2011) Comparison of sub-chronic metabolic effects of stable forms of naturally occurring GIP(1-30) and GIP(1-42) in high-fat fed mice. J Endocrinol. 208: 265-71.
    • (2011) J Endocrinol , vol.208 , pp. 265-271
    • Gault, V.A.1    Porter, D.W.2    Irwin, N.3    Flatt, P.R.4
  • 12
    • 77955611520 scopus 로고    scopus 로고
    • Therapeutic potential of the original incretin hormone glucose-dependent insulinotropic polypeptide: diabetes, obesity, osteoporosis and Alzheimer's disease? Expert Opin Investig Drugs
    • Irwin N, Gault V, Flatt PR, (2010) Therapeutic potential of the original incretin hormone glucose-dependent insulinotropic polypeptide: diabetes, obesity, osteoporosis and Alzheimer's disease? Expert Opin Investig Drugs. 19: 1039-48.
    • (2010) , vol.19 , pp. 1039-1048
    • Irwin, N.1    Gault, V.2    Flatt, P.R.3
  • 13
    • 77949693550 scopus 로고    scopus 로고
    • A GIP receptor agonist exhibits beta-cell anti-apoptotic actions in rat models of diabetes resulting in improved beta-cell function and glycemic control
    • Widenmaier SB, Kim SJ, Yang GK, De Los Reyes T, Nian C, et al. (2010) A GIP receptor agonist exhibits beta-cell anti-apoptotic actions in rat models of diabetes resulting in improved beta-cell function and glycemic control. PLoS One. 5: e9590.
    • (2010) PLoS One , vol.5
    • Widenmaier, S.B.1    Kim, S.J.2    Yang, G.K.3    de Los Reyes, T.4    Nian, C.5
  • 14
    • 0032895556 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide stimulation of lipolysis in differentiated 3T3-L1 cells: wortmannin-sensitive inhibition by insulin
    • McIntosh CHS, Bremsak I, Lynn FC, Gill R, Hinke SA, et al. (1999) Glucose-dependent insulinotropic polypeptide stimulation of lipolysis in differentiated 3T3-L1 cells: wortmannin-sensitive inhibition by insulin. Endocrinology. 140: 398-404.
    • (1999) Endocrinology , vol.140 , pp. 398-404
    • McIntosh, C.H.S.1    Bremsak, I.2    Lynn, F.C.3    Gill, R.4    Hinke, S.A.5
  • 15
    • 34247880256 scopus 로고    scopus 로고
    • Activation of lipoprotein lipase by glucose-dependent insulinotropic polypeptide in adipocytes.A role for a protein kinase B, LKB1, and AMP-activated protein kinase cascade
    • Kim SJ, Nian C, McIntosh CHS, (2007) Activation of lipoprotein lipase by glucose-dependent insulinotropic polypeptide in adipocytes. A role for a protein kinase B, LKB1, and AMP-activated protein kinase cascade. J Biol Chem. 282: 8557-8567.
    • (2007) J Biol Chem , vol.282 , pp. 8557-8567
    • Kim, S.J.1    Nian, C.2    McIntosh, C.H.S.3
  • 16
    • 36349012043 scopus 로고    scopus 로고
    • Resistin is a key mediator of glucose-dependent insulinotropic polypeptide (GIP) stimulation of lipoprotein lipase (LPL) activity in adipocytes
    • Kim SJ, Nian C, McIntosh CHS, (2007) Resistin is a key mediator of glucose-dependent insulinotropic polypeptide (GIP) stimulation of lipoprotein lipase (LPL) activity in adipocytes. J Biol Chem. 282: 34139-34147.
    • (2007) J Biol Chem , vol.282 , pp. 34139-34147
    • Kim, S.J.1    Nian, C.2    McIntosh, C.H.S.3
  • 17
    • 78149350158 scopus 로고    scopus 로고
    • GIP increases human adipocyte LPL expression through CREB and TORC2-mediated trans-activation of the LPL gene
    • Kim SJ, Nian C, McIntosh CHS, (2010) GIP increases human adipocyte LPL expression through CREB and TORC2-mediated trans-activation of the LPL gene. J Lipid Res 51: 3145-572010.
    • (2010) J Lipid Res , vol.51 , pp. 3145-572010
    • Kim, S.J.1    Nian, C.2    McIntosh, C.H.S.3
  • 18
    • 79953307026 scopus 로고    scopus 로고
    • Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation
    • Kim SJ, Nian C, McIntosh CHS, (2011) Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARγ and histone acetylation. J Lipid Res 52: 759-70.
    • (2011) J Lipid Res , vol.52 , pp. 759-770
    • Kim, S.J.1    Nian, C.2    McIntosh, C.H.S.3
  • 19
    • 36549010103 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation
    • Song DH, Getty-Kaushik L, Tseng E, Simon J, Corkey BE, et al. (2007) Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation. Gastroenterology. 133: 1796-805.
    • (2007) Gastroenterology , vol.133 , pp. 1796-1805
    • Song, D.H.1    Getty-Kaushik, L.2    Tseng, E.3    Simon, J.4    Corkey, B.E.5
  • 20
    • 33846893661 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide modulates adipocyte lipolysis and reesterification
    • Getty-Kaushik L, Song DH, Boylan MO, Corkey BE, Wolfe MM, (2006) Glucose-dependent insulinotropic polypeptide modulates adipocyte lipolysis and reesterification. Obesity (Silver Spring). 14: 1124-31.
    • (2006) Obesity (Silver Spring) , vol.14 , pp. 1124-1131
    • Getty-Kaushik, L.1    Song, D.H.2    Boylan, M.O.3    Corkey, B.E.4    Wolfe, M.M.5
  • 21
    • 83355173938 scopus 로고    scopus 로고
    • Gastric inhibitory peptide controls adipose insulin sensitivity via activation of CREB and p110β isoform of PI3 kinase
    • Mohammad S, Ramos LS, Buck J, Levin LR, Rubino F, et al. (2011) Gastric inhibitory peptide controls adipose insulin sensitivity via activation of CREB and p110β isoform of PI3 kinase. J Biol Chem. 286: 43062-70.
    • (2011) J Biol Chem , vol.286 , pp. 43062-43070
    • Mohammad, S.1    Ramos, L.S.2    Buck, J.3    Levin, L.R.4    Rubino, F.5
  • 22
    • 0036068322 scopus 로고    scopus 로고
    • Inhibition of gastric inhibitory polypeptide signaling prevents obesity
    • Miyawaki K, Yamada Y, Ban N, Ihara Y, Tsukiyama K, et al. (2002) Inhibition of gastric inhibitory polypeptide signaling prevents obesity. Nature Medicine 8: 738-742.
    • (2002) Nature Medicine , vol.8 , pp. 738-742
    • Miyawaki, K.1    Yamada, Y.2    Ban, N.3    Ihara, Y.4    Tsukiyama, K.5
  • 23
    • 77958050591 scopus 로고    scopus 로고
    • High-fat feeding stimulates endocrine, glucose-dependent insulinotropic polypeptide (GIP)-expressing cell hyperplasia in the duodenum of Wistar rats
    • Gniuli D, Calcagno A, Dalla Libera L, Calvani R, Leccesi L, et al. (2010) High-fat feeding stimulates endocrine, glucose-dependent insulinotropic polypeptide (GIP)-expressing cell hyperplasia in the duodenum of Wistar rats. Diabetologia. 53: 2233-40.
    • (2010) Diabetologia , vol.53 , pp. 2233-2240
    • Gniuli, D.1    Calcagno, A.2    Dalla Libera, L.3    Calvani, R.4    Leccesi, L.5
  • 24
    • 68449083816 scopus 로고    scopus 로고
    • Evidence for beneficial effects of compromised gastric inhibitory polypeptide action in obesity-related diabetes and possible therapeutic implications
    • Irwin N, Flatt PR, (2009) Evidence for beneficial effects of compromised gastric inhibitory polypeptide action in obesity-related diabetes and possible therapeutic implications. Diabetologia 52: 1724-1731.
    • (2009) Diabetologia , vol.52 , pp. 1724-1731
    • Irwin, N.1    Flatt, P.R.2
  • 25
    • 37149047560 scopus 로고    scopus 로고
    • GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet
    • McClean PL, Irwin N, Cassidy RS, Holst JJ, Gault VA, et al. (2007) GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet. Am J Physiol Endocrinol Metab 293: E1746-55.
    • (2007) Am J Physiol Endocrinol Metab , vol.293
    • McClean, P.L.1    Irwin, N.2    Cassidy, R.S.3    Holst, J.J.4    Gault, V.A.5
  • 26
    • 49649125933 scopus 로고    scopus 로고
    • Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet
    • Althage MC, Ford EL, Wang S, Tso P, Polonsky KS, et al. (2008) Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet. J Biol Chem. 283: 18365-76.
    • (2008) J Biol Chem , vol.283 , pp. 18365-18376
    • Althage, M.C.1    Ford, E.L.2    Wang, S.3    Tso, P.4    Polonsky, K.S.5
  • 28
    • 0034118750 scopus 로고    scopus 로고
    • Role of glucose in chronic desensitization of isolated rat islets and mouse insulinoma (betaTC-3) cells to glucose-dependent insulinotropic polypeptide
    • Hinke SA, Pauly RP, Ehses J, Kerridge P, Demuth HU, et al. (2000) Role of glucose in chronic desensitization of isolated rat islets and mouse insulinoma (betaTC-3) cells to glucose-dependent insulinotropic polypeptide. J Endocrinol. 165: 281-91.
    • (2000) J Endocrinol , vol.165 , pp. 281-291
    • Hinke, S.A.1    Pauly, R.P.2    Ehses, J.3    Kerridge, P.4    Demuth, H.U.5
  • 29
    • 34147142997 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic peptide-overexpressing transgenic mice have increased bone mass
    • Xie D, Zhong Q, Ding KH, Cheng H, Williams S, et al. (2007) Glucose-dependent insulinotropic peptide-overexpressing transgenic mice have increased bone mass. Bone. 40: 1352-60.
    • (2007) Bone , vol.40 , pp. 1352-1360
    • Xie, D.1    Zhong, Q.2    Ding, K.H.3    Cheng, H.4    Williams, S.5
  • 30
    • 34250710450 scopus 로고    scopus 로고
    • Adipose tissue function and plasticity orchestrate nutritional adaptation
    • Sethi J, Vudal-Puig A, (2007) Adipose tissue function and plasticity orchestrate nutritional adaptation. J Lipid Res. 48: 1253-1262.
    • (2007) J Lipid Res , vol.48 , pp. 1253-1262
    • Sethi, J.1    Vudal-Puig, A.2
  • 31
    • 34848872799 scopus 로고    scopus 로고
    • Obesity-associated improvements in metabolic profile through expansion of adipose tissue
    • Kim JY, van de Wall E, Laplante M, Azzara A, Trujillo ME, et al. (2007) Obesity-associated improvements in metabolic profile through expansion of adipose tissue. J Clin Invest. 117: 2621-37.
    • (2007) J Clin Invest , vol.117 , pp. 2621-2637
    • Kim, J.Y.1    van de Wall, E.2    Laplante, M.3    Azzara, A.4    Trujillo, M.E.5
  • 32
    • 4143075930 scopus 로고    scopus 로고
    • Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents fatty-acid-induced insulin resistance in the rat: comparison with metformin
    • Ye JM, Dzamko N, Cleasby ME, Hegarty BD, Furler SM, et al. (2004) Direct demonstration of lipid sequestration as a mechanism by which rosiglitazone prevents fatty-acid-induced insulin resistance in the rat: comparison with metformin. Diabetologia. 47: 1306-13.
    • (2004) Diabetologia , vol.47 , pp. 1306-1313
    • Ye, J.M.1    Dzamko, N.2    Cleasby, M.E.3    Hegarty, B.D.4    Furler, S.M.5
  • 33
    • 0007866067 scopus 로고    scopus 로고
    • Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice
    • Miyawaki K, Yamada Y, Yano H, Niwa H, Ban N, et al. (1999) Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice. Proc Natl Acad Sci U S A. 96: 14843-14847.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 14843-14847
    • Miyawaki, K.1    Yamada, Y.2    Yano, H.3    Niwa, H.4    Ban, N.5
  • 34
    • 33845997750 scopus 로고    scopus 로고
    • Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure
    • Hansotia T, Maida A, Flock G, Yamada Y, Tsukiyama K, et al. (2007) Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure. J Clin Invest. 117: 143-52.
    • (2007) J Clin Invest , vol.117 , pp. 143-152
    • Hansotia, T.1    Maida, A.2    Flock, G.3    Yamada, Y.4    Tsukiyama, K.5
  • 35
    • 33845596741 scopus 로고    scopus 로고
    • Increase in glucose-6-phosphate dehydrogenase in adipocytes stimulates oxidative stress and inflammatory signals
    • Park J, Choe SS, Choi AH, Kim KH, Yoon MJ, et al. (2006) Increase in glucose-6-phosphate dehydrogenase in adipocytes stimulates oxidative stress and inflammatory signals. Diabetes. 55: 2939-49.
    • (2006) Diabetes , vol.55 , pp. 2939-2949
    • Park, J.1    Choe, S.S.2    Choi, A.H.3    Kim, K.H.4    Yoon, M.J.5
  • 36
    • 44349141660 scopus 로고    scopus 로고
    • Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance
    • Jayasooriya AP, Mathai ML, Walker LL, Begg DP, Denton DA, et al. (2008) Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance. Proc Natl Acad Sci U S A. 105: 6531-6.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 6531-6536
    • Jayasooriya, A.P.1    Mathai, M.L.2    Walker, L.L.3    Begg, D.P.4    Denton, D.A.5
  • 37
    • 79957815398 scopus 로고    scopus 로고
    • Adipocyte-derived lipids increase angiotensin-converting enzyme (ACE) expression and modulate macrophage phenotype
    • Kohlstedt K, Trouvain C, Namgaladze D, Fleming I, (2011) Adipocyte-derived lipids increase angiotensin-converting enzyme (ACE) expression and modulate macrophage phenotype. Basic Res Cardiol. 106: 205-15.
    • (2011) Basic Res Cardiol , vol.106 , pp. 205-215
    • Kohlstedt, K.1    Trouvain, C.2    Namgaladze, D.3    Fleming, I.4
  • 38
    • 0347579845 scopus 로고    scopus 로고
    • Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide
    • Nisoli E, Clementi E, Paolucci C, Cozzi V, Tonello CS, et al. (2003) Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide. Science. 299: 896-9.
    • (2003) Science , vol.299 , pp. 896-899
    • Nisoli, E.1    Clementi, E.2    Paolucci, C.3    Cozzi, V.4    Tonello, C.S.5
  • 39
    • 33749442351 scopus 로고    scopus 로고
    • TNF-alpha downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents
    • Valerio A, Cardile A, Cozzi V, Bracale R, Tedesco L, et al. (2006) TNF-alpha downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents. J Clin Invest. 116: 2791-8.
    • (2006) J Clin Invest , vol.116 , pp. 2791-2798
    • Valerio, A.1    Cardile, A.2    Cozzi, V.3    Bracale, R.4    Tedesco, L.5
  • 40
    • 34447511610 scopus 로고    scopus 로고
    • Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation
    • Crunkhorn S, Dearie F, Mantzoros C, Gami H, da Silva WS, et al. (2007) Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation. J Biol Chem. 282: 15439-50.
    • (2007) J Biol Chem , vol.282 , pp. 15439-15450
    • Crunkhorn, S.1    Dearie, F.2    Mantzoros, C.3    Gami, H.4    da Silva, W.S.5
  • 41
    • 77953749940 scopus 로고    scopus 로고
    • Uncoupling protein-2 and the potential link between metabolism and longevity
    • Andrews ZB, (2010) Uncoupling protein-2 and the potential link between metabolism and longevity. Curr Aging Sci. 3: 102-12.
    • (2010) Curr Aging Sci , vol.3 , pp. 102-112
    • Andrews, Z.B.1
  • 42
    • 78049307571 scopus 로고    scopus 로고
    • Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: the role of eNOS, p38 MAPK, and AMPK pathways
    • Tedesco L, Valerio A, Dossena M, Cardile A, Ragni M, et al. (2010) Cannabinoid receptor stimulation impairs mitochondrial biogenesis in mouse white adipose tissue, muscle, and liver: the role of eNOS, p38 MAPK, and AMPK pathways. Diabetes. 59: 2826-36.
    • (2010) Diabetes , vol.59 , pp. 2826-2836
    • Tedesco, L.1    Valerio, A.2    Dossena, M.3    Cardile, A.4    Ragni, M.5
  • 43
    • 80155126156 scopus 로고    scopus 로고
    • PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis
    • Bhalla K, Hwang BJ, Dewi RE, Ou L, Twaddel W, et al. (2011) PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis. Cancer Res. 71: 6888-98.
    • (2011) Cancer Res , vol.71 , pp. 6888-6898
    • Bhalla, K.1    Hwang, B.J.2    Dewi, R.E.3    Ou, L.4    Twaddel, W.5
  • 44
    • 77952703424 scopus 로고    scopus 로고
    • Phosphoenolpyruvate carboxykinase (Pck1) helps regulate the triglyceride/fatty acid cycle and development of insulin resistance in mice
    • Millward CA, Desantis D, Hsieh CW, Heaney JD, Pisano S, et al. (2010) Phosphoenolpyruvate carboxykinase (Pck1) helps regulate the triglyceride/fatty acid cycle and development of insulin resistance in mice. J Lipid Res. 51: 1452-63.
    • (2010) J Lipid Res , vol.51 , pp. 1452-1463
    • Millward, C.A.1    Desantis, D.2    Hsieh, C.W.3    Heaney, J.D.4    Pisano, S.5
  • 45
    • 77449101244 scopus 로고    scopus 로고
    • A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes
    • Butler AA, Kozak LP, (2010) A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes. Diabetes. 59: 323-9.
    • (2010) Diabetes , vol.59 , pp. 323-329
    • Butler, A.A.1    Kozak, L.P.2
  • 46
    • 78651084780 scopus 로고    scopus 로고
    • Prolonged GIP receptor activation improves cognitive function, hippocampal synaptic plasticity and glucose homeostasis in high-fat fed mice
    • Porter DW, Irwin N, Flatt PR, Hölscher C, Gault VA, (2011) Prolonged GIP receptor activation improves cognitive function, hippocampal synaptic plasticity and glucose homeostasis in high-fat fed mice. Eur J Pharmacol. 650: 688-93.
    • (2011) Eur J Pharmacol , vol.650 , pp. 688-693
    • Porter, D.W.1    Irwin, N.2    Flatt, P.R.3    Hölscher, C.4    Gault, V.A.5
  • 47
    • 79955137934 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide receptor knockout mice are impaired in learning, synaptic plasticity, and neurogenesis
    • Faivre E, Gault VA, Thorens B, Hölscher C, (2011) Glucose-dependent insulinotropic polypeptide receptor knockout mice are impaired in learning, synaptic plasticity, and neurogenesis. J Neurophysiol. 105: 1574-80.
    • (2011) J Neurophysiol , vol.105 , pp. 1574-1580
    • Faivre, E.1    Gault, V.A.2    Thorens, B.3    Hölscher, C.4
  • 48
    • 34547444040 scopus 로고    scopus 로고
    • Immunohistochemical distribution of glucose-dependent insulinotropic polypeptide in the adult rat brain
    • Nyberg J, Jacobsson C, Anderson MF, Eriksson PS, (2007) Immunohistochemical distribution of glucose-dependent insulinotropic polypeptide in the adult rat brain. J Neurosci Res. 85: 2099-119.
    • (2007) J Neurosci Res , vol.85 , pp. 2099-2119
    • Nyberg, J.1    Jacobsson, C.2    Anderson, M.F.3    Eriksson, P.S.4
  • 49
    • 33751019967 scopus 로고    scopus 로고
    • Effects of glucose-dependent insulinotropic peptide on behavior
    • Ding KH, Zhong Q, Xie D, Chen HX, Della-Fera MA, et al. (2006) Effects of glucose-dependent insulinotropic peptide on behavior. Peptides. 27: 2750-5.
    • (2006) Peptides , vol.27 , pp. 2750-2755
    • Ding, K.H.1    Zhong, Q.2    Xie, D.3    Chen, H.X.4    Della-Fera, M.A.5
  • 50
    • 37249019491 scopus 로고    scopus 로고
    • The neonatal ventromedial hypothalamus transcriptome reveals novel markers with spatially distinct patterning
    • Kurrasch DM, Cheung CC, Lee FY, Tran PV, Hata K, et al. (2007) The neonatal ventromedial hypothalamus transcriptome reveals novel markers with spatially distinct patterning. J Neurosci. 27: 13624-34.
    • (2007) J Neurosci , vol.27 , pp. 13624-13634
    • Kurrasch, D.M.1    Cheung, C.C.2    Lee, F.Y.3    Tran, P.V.4    Hata, K.5
  • 51
    • 72449209171 scopus 로고    scopus 로고
    • PACAP neurons in the hypothalamic ventromedial nucleus are targets of central leptin signaling
    • Hawke Z, Ivanov TR, Bechtold DA, Dhillon H, Lowell BB, et al. (2009) PACAP neurons in the hypothalamic ventromedial nucleus are targets of central leptin signaling. J Neurosci. 29: 14828-14835.
    • (2009) J Neurosci , vol.29 , pp. 14828-14835
    • Hawke, Z.1    Ivanov, T.R.2    Bechtold, D.A.3    Dhillon, H.4    Lowell, B.B.5
  • 52
    • 33645400603 scopus 로고    scopus 로고
    • Effects on glucose homeostasis and insulin secretion of long term activation of the glucose-dependent insulinotropic polypeptide (GIP) receptor by N-AcGIP(LysPAL37) in normal mice
    • Irwin N, Green BD, Gault VA, Cassidy RS, O'Harte FP, et al. (2006) Effects on glucose homeostasis and insulin secretion of long term activation of the glucose-dependent insulinotropic polypeptide (GIP) receptor by N-AcGIP(LysPAL37) in normal mice. Peptides. 27: 893-900.
    • (2006) Peptides , vol.27 , pp. 893-900
    • Irwin, N.1    Green, B.D.2    Gault, V.A.3    Cassidy, R.S.4    O'Harte, F.P.5
  • 53
    • 69349096792 scopus 로고    scopus 로고
    • Fatty acid derivatised analogues of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties
    • Kerr BD, Irwin N, O'Harte FP, Bailey CJ, Flatt PR, et al. (2009) Fatty acid derivatised analogues of glucose-dependent insulinotropic polypeptide with improved antihyperglycaemic and insulinotropic properties. Biochem Pharmacol. 78: 1008-16.
    • (2009) Biochem Pharmacol , vol.78 , pp. 1008-1016
    • Kerr, B.D.1    Irwin, N.2    O'Harte, F.P.3    Bailey, C.J.4    Flatt, P.R.5
  • 54
    • 84855544372 scopus 로고    scopus 로고
    • Effects of acute and chronic administration of GIP analogues on cognition, synaptic plasticity and neurogenesis in mice
    • Faivre E, Hamilton A, Hölscher C, (2012) Effects of acute and chronic administration of GIP analogues on cognition, synaptic plasticity and neurogenesis in mice. Eur J Pharmacol. 2012 Jan 15 674(2-3): 294-306.
    • (2012) Eur J Pharmacol , vol.674 , Issue.2-3 , pp. 294-306
    • Faivre, E.1    Hamilton, A.2    Hölscher, C.3
  • 55
    • 0027182948 scopus 로고
    • Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice
    • Palmiter RD, Sandgren EP, Koeller DM, Brinster RL, (1993) Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice. Mol Cell Biol. 13: 5266-75.
    • (1993) Mol Cell Biol , vol.13 , pp. 5266-5275
    • Palmiter, R.D.1    Sandgren, E.P.2    Koeller, D.M.3    Brinster, R.L.4


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