-
1
-
-
0027235323
-
Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells
-
Ämmälä C, Ashcroft FM & Rorsman P 1993 Calcium-independent potentiation of insulin release by cyclic AMP in single β-cells. Nature 363 356-358.
-
(1993)
Nature
, vol.363
, pp. 356-358
-
-
Ämmälä, C.1
Ashcroft, F.M.2
Rorsman, P.3
-
2
-
-
0023785319
-
Mechanisms of glucagon-induced homologous and heterologous desensitization of adenylate cyclase in membranes and whole Sertoli cells of the rat
-
Attramadal H, Eikvar L & Hansson V 1988 Mechanisms of glucagon-induced homologous and heterologous desensitization of adenylate cyclase in membranes and whole Sertoli cells of the rat. Endocrinology 123 1060-1068.
-
(1988)
Endocrinology
, vol.123
, pp. 1060-1068
-
-
Attramadal, H.1
Eikvar, L.2
Hansson, V.3
-
3
-
-
0031059468
-
Regulatory mechanisms that modulate signalling by G-protein-coupled receptors
-
Böhm SK, Grady EF & Bunnett NW 1997 Regulatory mechanisms that modulate signalling by G-protein-coupled receptors. Biochemical Journal 322 1-18.
-
(1997)
Biochemical Journal
, vol.322
, pp. 1-18
-
-
Böhm, S.K.1
Grady, E.F.2
Bunnett, N.W.3
-
4
-
-
0023947320
-
Characteristics of desensitization of insulin secretion in fully in vitro systems
-
Bolaffi JL, Bruno L, Heldt A & Grodsky GM 1988 Characteristics of desensitization of insulin secretion in fully in vitro systems. Endocrinology 122 1801-1809.
-
(1988)
Endocrinology
, vol.122
, pp. 1801-1809
-
-
Bolaffi, J.L.1
Bruno, L.2
Heldt, A.3
Grodsky, G.M.4
-
6
-
-
0030785760
-
Peptide hormone regulation of islet cells
-
D'Alessio D 1997 Peptide hormone regulation of islet cells. Hormone and Metabolic Research 29 297-300.
-
(1997)
Hormone and Metabolic Research
, vol.29
, pp. 297-300
-
-
D'Alessio, D.1
-
7
-
-
0030945044
-
Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic β-cells by glucose-dependent insulinotropic polypeptide
-
Ding W-G & Gromada J 1997 Protein kinase A-dependent stimulation of exocytosis in mouse pancreatic β-cells by glucose-dependent insulinotropic polypeptide. Diabetes 46 615-621.
-
(1997)
Diabetes
, vol.46
, pp. 615-621
-
-
Ding, W.-G.1
Gromada, J.2
-
8
-
-
0000181874
-
Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene
-
Efrat S, Linde S, Kofod H, Spector D, Delannoy M, Grant S, Hanahan D & Baekkeskov S 1988 Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene. Cell Biology 85 9037-9041.
-
(1988)
Cell Biology
, vol.85
, pp. 9037-9041
-
-
Efrat, S.1
Linde, S.2
Kofod, H.3
Spector, D.4
Delannoy, M.5
Grant, S.6
Hanahan, D.7
Baekkeskov, S.8
-
9
-
-
0021194112
-
The enteric enhancement of glucose stimulated insulin release. The role of GIP in aging, obesity and noninsulin-dependent diabetes
-
Elahi D, Andersen DK, Muller DC, Tobin JD, Brown JC & Andres R 1984 The enteric enhancement of glucose stimulated insulin release. The role of GIP in aging, obesity and noninsulin-dependent diabetes. Diabetes 33 950-957.
-
(1984)
Diabetes
, vol.33
, pp. 950-957
-
-
Elahi, D.1
Andersen, D.K.2
Muller, D.C.3
Tobin, J.D.4
Brown, J.C.5
Andres, R.6
-
10
-
-
0028224617
-
The insulinotropic actions of glucose dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (7-37) in normal and diabetic subjects
-
Elahi D, McAloon-Dyke M, Fukagawa NK, Meneilly GS, Sclater AL, Minaker KL, Habener JF & Andersen DK 1994 The insulinotropic actions of glucose dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (7-37) in normal and diabetic subjects. Regulatory Peptides 51 63-74.
-
(1994)
Regulatory Peptides
, vol.51
, pp. 63-74
-
-
Elahi, D.1
McAloon-Dyke, M.2
Fukagawa, N.K.3
Meneilly, G.S.4
Sclater, A.L.5
Minaker, K.L.6
Habener, J.F.7
Andersen, D.K.8
-
11
-
-
0025912938
-
Homologous desensitization of the insulinotropic glucagon-like peptide-I(7-37) receptor on insulinoma (HIT-T15) cells
-
Fehmann HC & Habener JF 1991 Homologous desensitization of the insulinotropic glucagon-like peptide-I(7-37) receptor on insulinoma (HIT-T15) cells. Endocrinology 128 2880-2888.
-
(1991)
Endocrinology
, vol.128
, pp. 2880-2888
-
-
Fehmann, H.C.1
Habener, J.F.2
-
12
-
-
0021237955
-
Gastric inhibitory polypeptide (GIP), pancreatic glucagon, and vasoactive intestinal peptide (VIP) are cAMP-inducing hormones in the human gastric cancer cell line HGT-1. Homologous desensitization of VIP receptor activity
-
Gespach C, Emami S & Rosselin G 1984 Gastric inhibitory polypeptide (GIP), pancreatic glucagon, and vasoactive intestinal peptide (VIP) are cAMP-inducing hormones in the human gastric cancer cell line HGT-1. Homologous desensitization of VIP receptor activity. Biochemical and Biophysical Research Communications 120 641-649.
-
(1984)
Biochemical and Biophysical Research Communications
, vol.120
, pp. 641-649
-
-
Gespach, C.1
Emami, S.2
Rosselin, G.3
-
13
-
-
0024807859
-
A new phase of insulin secretion. How will it contribute to our understanding of beta-cell function?
-
Grodsky GM 1989 A new phase of insulin secretion. How will it contribute to our understanding of beta-cell function? Diabetes 38 673-678.
-
(1989)
Diabetes
, vol.38
, pp. 673-678
-
-
Grodsky, G.M.1
-
14
-
-
0029891089
-
Desensitization of glucagon-like peptide-1 receptor in insulin-secreting βTC-3 cells: Role of PKA-independent mechanisms
-
Gromada J, Dissing S & Rorsman P 1996 Desensitization of glucagon-like peptide-1 receptor in insulin-secreting βTC-3 cells: role of PKA-independent mechanisms. British Journal of Pharmacology 118 769-775.
-
(1996)
British Journal of Pharmacology
, vol.118
, pp. 769-775
-
-
Gromada, J.1
Dissing, S.2
Rorsman, P.3
-
15
-
-
0028945815
-
Effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-I-(7-36) on insulin secretion
-
Jia X, Brown JC, Ma P, Pederson RA & McIntosh CHS 1995 Effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-I-(7-36) on insulin secretion. American Journal of Physiology 268 E645-E651.
-
(1995)
American Journal of Physiology
, vol.268
-
-
Jia, X.1
Brown, J.C.2
Ma, P.3
Pederson, R.A.4
McIntosh, C.H.S.5
-
16
-
-
0024511397
-
Glucose dependent insulinotropic polypeptide (GIP) infused intravenously is insulinotropic in the fasting state in type 2 (non-insulin dependent) diabetes mellitus
-
Jones IR, Owens DR, Luzio S & Hayes TM 1989 Glucose dependent insulinotropic polypeptide (GIP) infused intravenously is insulinotropic in the fasting state in type 2 (non-insulin dependent) diabetes mellitus. Hormone and Metabolic Research 21 23-26.
-
(1989)
Hormone and Metabolic Research
, vol.21
, pp. 23-26
-
-
Jones, I.R.1
Owens, D.R.2
Luzio, S.3
Hayes, T.M.4
-
17
-
-
0032586061
-
Gαi2-mRNA and -protein regulation as a mechanism for heterologous sensitization and desensitization of insulin secretion
-
Kesper S, Rucha J, Neve H, Mazenot C & Verspohl EJ 1999 Gαi2-mRNA and -protein regulation as a mechanism for heterologous sensitization and desensitization of insulin secretion. Cellular Signalling 11 759-768.
-
(1999)
Cellular Signalling
, vol.11
, pp. 759-768
-
-
Kesper, S.1
Rucha, J.2
Neve, H.3
Mazenot, C.4
Verspohl, E.J.5
-
18
-
-
0027891888
-
Glucose-dependent insulinotropic polypeptide stimulated insulin release from a tumour-derived β-cell line (βTC3)
-
Kieffer TJ, Verchere CB, Fell CD, Huang Z, Brown JC & Pederson RA 1993 Glucose-dependent insulinotropic polypeptide stimulated insulin release from a tumour-derived β-cell line (βTC3). Canadian Journal of Physiology and Pharmacology 71 917-922.
-
(1993)
Canadian Journal of Physiology and Pharmacology
, vol.71
, pp. 917-922
-
-
Kieffer, T.J.1
Verchere, C.B.2
Fell, C.D.3
Huang, Z.4
Brown, J.C.5
Pederson, R.A.6
-
19
-
-
0029118049
-
Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV
-
Kieffer TJ, McIntosh CHS & Pederson RA 1995 Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV. Endocrinology 136 3585-3596.
-
(1995)
Endocrinology
, vol.136
, pp. 3585-3596
-
-
Kieffer, T.J.1
McIntosh, C.H.S.2
Pederson, R.A.3
-
20
-
-
0031560912
-
Gastric inhibitory polypeptide activates MAP kinase through the wortmannin-sensitive and -insensitive pathways
-
Kubota A, Yamada Y, Yasuda K, Someya Y, Ihara Y, Kagimoto S, Watanabe R, Kuroe A, Ishida H & Seino Y 1997 Gastric inhibitory polypeptide activates MAP kinase through the wortmannin-sensitive and -insensitive pathways. Biochemical and Biophysical Research Communications 235 171-175.
-
(1997)
Biochemical and Biophysical Research Communications
, vol.235
, pp. 171-175
-
-
Kubota, A.1
Yamada, Y.2
Yasuda, K.3
Someya, Y.4
Ihara, Y.5
Kagimoto, S.6
Watanabe, R.7
Kuroe, A.8
Ishida, H.9
Seino, Y.10
-
21
-
-
0027393644
-
The role of the free cytosolic calcium level in β-cell signal transduction by gastric-inhibitory polypeptide and glucagon-like peptide I(7-37)
-
Lu M, Wheeler MB, Leng X-H & Boyd AE 1993 The role of the free cytosolic calcium level in β-cell signal transduction by gastric-inhibitory polypeptide and glucagon-like peptide I(7-37). Endocrinology 132 94-100.
-
(1993)
Endocrinology
, vol.132
, pp. 94-100
-
-
Lu, M.1
Wheeler, M.B.2
Leng, X.-H.3
Boyd, A.E.4
-
22
-
-
13344293675
-
Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic polypeptide receptors in rat pancreatic islet cells
-
Moens K, Heimberg H, Flamez D, Huypens P, Quartier E, Ling Z, Pipeleers D, Gremlich S, Thorens B & Schuit F 1996 Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic polypeptide receptors in rat pancreatic islet cells. Diabetes 45 257-261.
-
(1996)
Diabetes
, vol.45
, pp. 257-261
-
-
Moens, K.1
Heimberg, H.2
Flamez, D.3
Huypens, P.4
Quartier, E.5
Ling, Z.6
Pipeleers, D.7
Gremlich, S.8
Thorens, B.9
Schuit, F.10
-
23
-
-
0027419106
-
Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1(7-36 amide) infused at near physiological insulinotropic hormone and glucose concentrations
-
Nauck MA, Bartels E, Orskøv C, Ebert R & Creutzfeldt W 1993a Additive insulinotropic effects of exogenous synthetic human gastric inhibitory polypeptide and glucagon-like peptide-1(7-36 amide) infused at near physiological insulinotropic hormone and glucose concentrations. Journal of Clinical Endocrinology and Metabolism 76 912-917.
-
(1993)
Journal of Clinical Endocrinology and Metabolism
, vol.76
, pp. 912-917
-
-
Nauck, M.A.1
Bartels, E.2
Orskøv, C.3
Ebert, R.4
Creutzfeldt, W.5
-
24
-
-
0027391607
-
Preserved incretin activity of glucagon-like peptide-1 (7-36amide), but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
-
Nauck MA, Heimesaat MM, Ørskov C, Holst JJ, Ebert R & Creutzfeldt W 1993b Preserved incretin activity of glucagon-like peptide-1 (7-36amide), but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. Journal of Clinical Investigation 91 301-307.
-
(1993)
Journal of Clinical Investigation
, vol.91
, pp. 301-307
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Ørskov, C.3
Holst, J.J.4
Ebert, R.5
Creutzfeldt, W.6
-
25
-
-
0029830703
-
Investigation of GIP1-42 and GLP-1 7-36 degradation in vitro by dipeptidyl peptidase IV (DPIV) using matrix-assisted laser desorption/ionization-time of flight mass spectometry (MALDI-TOF MS): A novel kinetic approach
-
Pauly RP, Rosche F, Wermann M, McIntosh CHS, Pederson RA & Demuth H-U 1996 Investigation of GIP1-42 and GLP-1 7-36 degradation in vitro by dipeptidyl peptidase IV (DPIV) using matrix-assisted laser desorption/ionization-time of flight mass spectometry (MALDI-TOF MS): a novel kinetic approach. Journal of Biological Chemistry 271 23222-23229.
-
(1996)
Journal of Biological Chemistry
, vol.271
, pp. 23222-23229
-
-
Pauly, R.P.1
Rosche, F.2
Wermann, M.3
McIntosh, C.H.S.4
Pederson, R.A.5
Demuth, H.-U.6
-
26
-
-
0032969356
-
Improved glucose tolerance in rats treated with the dipeptidyl peptidase IV (CD26) inhibitor ile-thiazolidide
-
Pauly RP, Demuth H-U, Rosche F, Schmidt J, White HA, Lynn F, McIntosh CHS & Pederson RA 1999 Improved glucose tolerance in rats treated with the dipeptidyl peptidase IV (CD26) inhibitor ile-thiazolidide. Metabolism 48 385-389.
-
(1999)
Metabolism
, vol.48
, pp. 385-389
-
-
Pauly, R.P.1
Demuth, H.-U.2
Rosche, F.3
Schmidt, J.4
White, H.A.5
Lynn, F.6
McIntosh, C.H.S.7
Pederson, R.A.8
-
27
-
-
0002632811
-
Gastric inhibitory polypeptide
-
Eds J Walsh & G Dockray. New York: Raven Press, Ltd.
-
Pederson RA 1994 Gastric inhibitory polypeptide. In Gut Peptides: Biochemistry and Physiology, pp 217-259. Eds J Walsh & G Dockray. New York: Raven Press, Ltd.
-
(1994)
Gut Peptides: Biochemistry and Physiology
, pp. 217-259
-
-
Pederson, R.A.1
-
28
-
-
0020464596
-
Effect of jejunoileal bypass in the rat on the enteroinsular axis
-
Pederson RA, Buchan AMJ, Zahedi-Asl S, Chan CB & Brown JC 1982 Effect of jejunoileal bypass in the rat on the enteroinsular axis. Regulatory Peptides 3 53-63.
-
(1982)
Regulatory Peptides
, vol.3
, pp. 53-63
-
-
Pederson, R.A.1
Buchan, A.M.J.2
Zahedi-Asl, S.3
Chan, C.B.4
Brown, J.C.5
-
29
-
-
0031870418
-
Improved glucose tolerance in zucker fatty rats by oral administration of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide
-
Pederson RA, White HA, Schlenzig D, Pauly RP, McIntosh CHS & Demuth H-U 1998 Improved glucose tolerance in zucker fatty rats by oral administration of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide. Diabetes 47 1253-1258.
-
(1998)
Diabetes
, vol.47
, pp. 1253-1258
-
-
Pederson, R.A.1
White, H.A.2
Schlenzig, D.3
Pauly, R.P.4
McIntosh, C.H.S.5
Demuth, H.-U.6
-
30
-
-
0029670405
-
Insulin-secreting cell lines: Classification, characteristics and potential applications
-
Poitout V, Olson LK & Robertson RP 1996 Insulin-secreting cell lines: classification, characteristics and potential applications. Diabetes and Metabolism 22 7-14.
-
(1996)
Diabetes and Metabolism
, vol.22
, pp. 7-14
-
-
Poitout, V.1
Olson, L.K.2
Robertson, R.P.3
-
31
-
-
0030792753
-
Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells
-
Renström E, Eliasson L & Rorsman P 1997 Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells. Journal of Physiology 1997 105-118.
-
(1997)
Journal of Physiology
, vol.1997
, pp. 105-118
-
-
Renström, E.1
Eliasson, L.2
Rorsman, P.3
-
32
-
-
0017377640
-
Hypersecretion of gastric inhibitory polypeptide following oral glucose in diabetes mellitus
-
Ross SA, Brown JC & Dupré J 1977 Hypersecretion of gastric inhibitory polypeptide following oral glucose in diabetes mellitus. Diabetes 26 525-529.
-
(1977)
Diabetes
, vol.26
, pp. 525-529
-
-
Ross, S.A.1
Brown, J.C.2
Dupré, J.3
-
34
-
-
0029945254
-
Signal transduction and desensitization of the glucagon-like peptide-1 receptor
-
Thorens B & Widmann C 1996 Signal transduction and desensitization of the glucagon-like peptide-1 receptor. Acta Physiologica Scandinavica 157 317-319.
-
(1996)
Acta Physiologica Scandinavica
, vol.157
, pp. 317-319
-
-
Thorens, B.1
Widmann, C.2
-
35
-
-
0032580293
-
The cysteine of the cytoplasmic tail of the glucose-dependent insulinotropic peptide receptor mediates its chronic desensitization and down-regulation
-
Tseng C-C & Zhang X-Y 1998a The cysteine of the cytoplasmic tail of the glucose-dependent insulinotropic peptide receptor mediates its chronic desensitization and down-regulation. Molecular and Cellular Endocrinology 139 179-186.
-
(1998)
Molecular and Cellular Endocrinology
, vol.139
, pp. 179-186
-
-
Tseng, C.-C.1
Zhang, X.-Y.2
-
36
-
-
0031767445
-
Role of regulator of G protein signaling in desensitization of the glucose-dependent insulinotropic peptide receptor
-
Tseng C-C & Zhang X-Y 1998b Role of regulator of G protein signaling in desensitization of the glucose-dependent insulinotropic peptide receptor. Endocrinology 139 4470-4475.
-
(1998)
Endocrinology
, vol.139
, pp. 4470-4475
-
-
Tseng, C.-C.1
Zhang, X.-Y.2
-
38
-
-
0027136670
-
Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain
-
Usdin TB, Mezey É, Button DC, Brownstein MJ & Bonner TI 1993 Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain. Endocrinology 133 2861-2870.
-
(1993)
Endocrinology
, vol.133
, pp. 2861-2870
-
-
Usdin, T.B.1
É, M.2
Button, D.C.3
Brownstein, M.J.4
Bonner, T.I.5
-
39
-
-
0023818603
-
Pancreatic islet isolation in rats with ductal collagenase distention, stationary digestion, and dextran separation
-
Van der Vliet JA, Meloche RM, Field MJ & Chen D 1988 Pancreatic islet isolation in rats with ductal collagenase distention, stationary digestion, and dextran separation. Transplantation 45 493-494.
-
(1988)
Transplantation
, vol.45
, pp. 493-494
-
-
Van Der Vliet, J.A.1
Meloche, R.M.2
Field, M.J.3
Chen, D.4
-
40
-
-
0029082308
-
Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: Ligand binding and intracellular signaling properties
-
Wheeler MB, Gelling RW, McIntosh CHS, Georgiou J, Brown JC & Pederson RA 1995 Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: ligand binding and intracellular signaling properties. Endocrinology 136 4629-4639.
-
(1995)
Endocrinology
, vol.136
, pp. 4629-4639
-
-
Wheeler, M.B.1
Gelling, R.W.2
McIntosh, C.H.S.3
Georgiou, J.4
Brown, J.C.5
Pederson, R.A.6
-
41
-
-
0033609824
-
Characterization of the carboxyl-terminal domain of the rat glucose-dependent insulinotropic polypeptide (GIP) receptor: A role for serines 426 and 427 in internalization
-
Wheeler MB, Gelling RW, Hinke SA, Tu B, Chandy MJ, Lynn FC, Ehses J, Pederson RA & McIntosh CHS 1999 Characterization of the carboxyl-terminal domain of the rat glucose-dependent insulinotropic polypeptide (GIP) receptor: a role for serines 426 and 427 in internalization. Journal of Biological Chemistry 274 24593-24601.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 24593-24601
-
-
Wheeler, M.B.1
Gelling, R.W.2
Hinke, S.A.3
Tu, B.4
Chandy, M.J.5
Lynn, F.C.6
Ehses, J.7
Pederson, R.A.8
McIntosh, C.H.S.9
-
42
-
-
0029810617
-
Heterologous desensitization of the glucagon-like peptide-1 receptor by phorbol esters requires phosphorylation of the cytoplasmic tail at four different sites
-
Widmann C, Dolci W & Thorens B 1995 Heterologous desensitization of the glucagon-like peptide-1 receptor by phorbol esters requires phosphorylation of the cytoplasmic tail at four different sites. Journal of Biological Chemistry 271 19957-19963.
-
(1995)
Journal of Biological Chemistry
, vol.271
, pp. 19957-19963
-
-
Widmann, C.1
Dolci, W.2
Thorens, B.3
-
43
-
-
0031001096
-
Internalization and homologous desensitization of the GLP-1 receptor depend on phosphorylation of the receptor carboxyl tail at the same three sites
-
Widmann C, Dolci W & Thorens B 1997 Internalization and homologous desensitization of the GLP-1 receptor depend on phosphorylation of the receptor carboxyl tail at the same three sites. Molecular Endocrinology 11 1094-1102.
-
(1997)
Molecular Endocrinology
, vol.11
, pp. 1094-1102
-
-
Widmann, C.1
Dolci, W.2
Thorens, B.3
|