G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice

Journal of Clinical Investigation

Volumn 122, Issue 7, 2012, Pages 2444-2453

  Osborn, Olivia ^a   Oh, Da Young ^a   McNelis, Joanne ^a   Sanchez Alavez, Manuel ^b   Talukdar, Saswata ^a   Lu, Min ^a   Li, PingPing ^a   Thiede, Lucinda ^c   Morinaga, Hidetaka ^a   Kim, Jane J ^d   Heinrichsdorff, Jan ^a   Nalbandian, Sarah ^a   Ofrecio, Jachelle M ^a   Scadeng, Miriam ^e   Schenk, Simon ^f   Hadcock, John ^c   Bartfai, Tamas ^b   Olefsky, Jerrold M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c PFIZER INC   (United States)

^d RADY CHILDREN'S HOSPITAL   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 21; INSULIN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW TRANSPLANTATION; CELL FRACTIONATION; CELL INFILTRATION; CHEMOTAXIS; CONTROLLED STUDY; ENERGY EXPENDITURE; EX VIVO STUDY; GENE DELETION; GENE EXPRESSION REGULATION; GENE INACTIVATION; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; GLUCOSE TOLERANCE TEST; HYPOTHALAMUS; IN VIVO STUDY; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; KNOCKOUT MOUSE; LIPID DIET; LIVER; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; OBESITY; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; THERMOGENESIS;

ANIMALS; BONE MARROW TRANSPLANTATION; DIET, HIGH-FAT; EATING; ENERGY METABOLISM; EPIDIDYMIS; GENE EXPRESSION PROFILING; GLUCOSE; HYPOTHALAMUS; INFLAMMATION MEDIATORS; INSULIN RESISTANCE; INTRA-ABDOMINAL FAT; LIVER; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OBESITY; PHENOTYPE; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, G-PROTEIN-COUPLED; SEQUENCE DELETION; TRANSCRIPTION, GENETIC; WEIGHT GAIN;

EID: 84863545528     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI61953     Document Type: Article

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