-
1
-
-
0029799638
-
Gene therapy in the United States: A five-year status report
-
Ross G, Erickson R, Knorr D, Motulsky AG, Parkman R, Samulski J, Straus SE, Smith BR. Gene therapy in the United States: a five-year status report. Hum. Gene Ther., 7, 1781-1790 (1996).
-
(1996)
Hum. Gene Ther.
, vol.7
, pp. 1781-1790
-
-
Ross, G.1
Erickson, R.2
Knorr, D.3
Motulsky, A.G.4
Parkman, R.5
Samulski, J.6
Straus, S.E.7
Smith, B.R.8
-
2
-
-
0028328261
-
Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy
-
Yang Y, Nunes FA, Berencsi K, Furth EE, Gönczöl E, Wilson JM. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc. Natl. Acad. Sci. U.S.A., 91, 4407-4411 (1994).
-
(1994)
Proc. Natl. Acad. Sci. U.S.A.
, vol.91
, pp. 4407-4411
-
-
Yang, Y.1
Nunes, F.A.2
Berencsi, K.3
Furth, E.E.4
Gönczöl, E.5
Wilson, J.M.6
-
3
-
-
0034632428
-
Transfer of interleukin-4 and interleukin-10 in patients with severe inflammatory bowel disease of the rectum
-
Rogy MA, Beinhauer BG, Reinisch W, Huang L, Pokieser P. Transfer of interleukin-4 and interleukin-10 in patients with severe inflammatory bowel disease of the rectum. Hum. Gene Ther., 11, 1731-1741 (2000).
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 1731-1741
-
-
Rogy, M.A.1
Beinhauer, B.G.2
Reinisch, W.3
Huang, L.4
Pokieser, P.5
-
4
-
-
0027517321
-
Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biologic activity, and lack of toxicity in humans
-
Nabel GJ, Nabel EG, Yang Z-Y, Fox BA, Plautz GE, Gao X, Huang L, Shu S, Gordon D, Chang AE. Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humans. Proc. Natl. Acad. Sci. U.S.A., 90, 11307-11311 (1993).
-
(1993)
Proc. Natl. Acad. Sci. U.S.A.
, vol.90
, pp. 11307-11311
-
-
Nabel, G.J.1
Nabel, E.G.2
Yang, Z.-Y.3
Fox, B.A.4
Plautz, G.E.5
Gao, X.6
Huang, L.7
Shu, S.8
Gordon, D.9
Chang, A.E.10
-
5
-
-
8244224532
-
Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer of an allogeneic histo-compatibility antigen, HLA-B7
-
Rubin J, Galanis E, Pitot HC, Richardson RL, Burch PA, Charboneau JW, Reading CC, Lewis BD, Stahl S, Akporiaye ET, Harris DT. Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer of an allogeneic histo-compatibility antigen, HLA-B7. Gene Ther., 4, 419-425 (1997).
-
(1997)
Gene Ther.
, vol.4
, pp. 419-425
-
-
Rubin, J.1
Galanis, E.2
Pitot, H.C.3
Richardson, R.L.4
Burch, P.A.5
Charboneau, J.W.6
Reading, C.C.7
Lewis, B.D.8
Stahl, S.9
Akporiaye, E.T.10
Harris, D.T.11
-
6
-
-
7444262947
-
Aerosol delivery of glucosylated polyethylenimine/phosphatase and tensin homologue deleted on chromosome 10 complex suppresses Akt downstream pathways in the lung of K-ras null mice
-
Kim HW, Park IK, Cho CS, Lee KH, Beck GR Jr, Colburn NH, Cho MH. Aerosol delivery of glucosylated polyethylenimine/phosphatase and tensin homologue deleted on chromosome 10 complex suppresses Akt downstream pathways in the lung of K-ras null mice. Cancer Res., 64, 7971-7976 (2004).
-
(2004)
Cancer Res.
, vol.64
, pp. 7971-7976
-
-
Kim, H.W.1
Park, I.K.2
Cho, C.S.3
Lee, K.H.4
Beck Jr., G.R.5
Colburn, N.H.6
Cho, M.H.7
-
7
-
-
45749158576
-
Enhanced lung gene expression after aerosol delivery of concentrated pDNA/PEI complexes
-
Davies LA, McLachlan G, Sumner-Jones SG, Ferguson D, Baker A, Tennant P, Gordon C, Vrettou C, Baker E, Zhu J, Alton EW, Collie DD, Porteous DJ, Hyde SC, Gill DR. Enhanced lung gene expression after aerosol delivery of concentrated pDNA/PEI complexes. Mol. Ther., 16, 1283-1290 (2008).
-
(2008)
Mol. Ther.
, vol.16
, pp. 1283-1290
-
-
Davies, L.A.1
McLachlan, G.2
Sumner-Jones, S.G.3
Ferguson, D.4
Baker, A.5
Tennant, P.6
Gordon, C.7
Vrettou, C.8
Baker, E.9
Zhu, J.10
Alton, E.W.11
Collie, D.D.12
Porteous, D.J.13
Hyde, S.C.14
Gill, D.R.15
-
8
-
-
9844237019
-
Safety of a single aerosol administration of escalating doses of the cationic lipid GL-67/DOPE/ DMPE-PEG5000 formulation to the lungs of normal volunteers
-
Chadwick SL, Kingston HD, Stern M, Cook RM, O'Connor BJ, Lukasson M, Balfour RP, Rosenberg M, Cheng SH, Smith AE, Meeker DP, Geddes DM, Alton EW. Safety of a single aerosol administration of escalating doses of the cationic lipid GL-67/DOPE/ DMPE-PEG5000 formulation to the lungs of normal volunteers. Gene Ther., 4, 937-942 (1997).
-
(1997)
Gene Ther.
, vol.4
, pp. 937-942
-
-
Chadwick, S.L.1
Kingston, H.D.2
Stern, M.3
Cook, R.M.4
O'Connor, B.J.5
Lukasson, M.6
Balfour, R.P.7
Rosenberg, M.8
Cheng, S.H.9
Smith, A.E.10
Meeker, D.P.11
Geddes, D.M.12
Alton, E.W.13
-
9
-
-
52449086630
-
Cospray dried antibiotics for dry powder lung delivery
-
Adi H, Young PM, Chan HK, Stewart P, Agus H, Traini D. Cospray dried antibiotics for dry powder lung delivery. J. Pharm. Sci., 97, 3356-3366 (2008).
-
(2008)
J. Pharm. Sci.
, vol.97
, pp. 3356-3366
-
-
Adi, H.1
Young, P.M.2
Chan, H.K.3
Stewart, P.4
Agus, H.5
Traini, D.6
-
10
-
-
38949106175
-
Application of supercritical fluid to preparation of powders of high-molecular weight drugs for inhalation
-
Okamoto H, Danjo K. Application of supercritical fluid to preparation of powders of high-molecular weight drugs for inhalation. Adv. Drug Deliv. Rev., 60, 433-446 (2008).
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, pp. 433-446
-
-
Okamoto, H.1
Danjo, K.2
-
11
-
-
0022529362
-
Some future perspectives for unit dose inhalation aerosols
-
Byron PR. Some future perspectives for unit dose inhalation aerosols. Drug Dev. Ind. Pharm., 12, 993-1015 (1986).
-
(1986)
Drug Dev. Ind. Pharm.
, vol.12
, pp. 993-1015
-
-
Byron, P.R.1
-
12
-
-
0028031785
-
Effect of different modes of inhalation on drug delivery from a dry powder inhaler
-
Newman SP, Hollingworth A, Clark AR. Effect of different modes of inhalation on drug delivery from a dry powder inhaler. Int. J. Pharm., 102, 127-132 (1994).
-
(1994)
Int. J. Pharm.
, vol.102
, pp. 127-132
-
-
Newman, S.P.1
Hollingworth, A.2
Clark, A.R.3
-
13
-
-
30044436097
-
Liposomal dry powders as aerosols for pulmonary delivery of proteins
-
Lu D, Hickey AJ. Liposomal dry powders as aerosols for pulmonary delivery of proteins. AAPS PharmSciTech, 6, E641-E648 (2005).
-
(2005)
AAPS PharmSciTech
, vol.6
-
-
Lu, D.1
Hickey, A.J.2
-
14
-
-
79960921592
-
Dry powder aerosols of polyethylenimine (PEI)-based gene vectors mediate efficient gene delivery to the lung
-
Pfeifer C, Hasenpusch G, Uezguen S, Aneja MK, Reinhardt D, Kirch J, Schneider M, Claus S, Friess W, Rudolph C. Dry powder aerosols of polyethylenimine (PEI)-based gene vectors mediate efficient gene delivery to the lung. J. Control. Release, 154, 69-76 (2011).
-
(2011)
J. Control. Release
, vol.154
, pp. 69-76
-
-
Pfeifer, C.1
Hasenpusch, G.2
Uezguen, S.3
Aneja, M.K.4
Reinhardt, D.5
Kirch, J.6
Schneider, M.7
Claus, S.8
Friess, W.9
Rudolph, C.10
-
15
-
-
18744380086
-
Acetaminophen particle design using chitosan and a spray-drying technique
-
Takahashi H, Chen R, Okamoto H, Danjo K. Acetaminophen particle design using chitosan and a spray-drying technique. Chem. Pharm. Bull., 53, 37-41 (2005).
-
(2005)
Chem. Pharm. Bull.
, vol.53
, pp. 37-41
-
-
Takahashi, H.1
Chen, R.2
Okamoto, H.3
Danjo, K.4
-
16
-
-
4644304289
-
Aerosolisation of beclomethasone dipropionate using spray dried lactose/polyethylene glycol carriers
-
Gilani K, Rouholamini Najafabadi A, Barghi M, Rafiee-Tehrani M. Aerosolisation of beclomethasone dipropionate using spray dried lactose/polyethylene glycol carriers. Eur. J. Pharm. Biopharm., 58, 595-606 (2004).
-
(2004)
Eur. J. Pharm. Biopharm.
, vol.58
, pp. 595-606
-
-
Gilani, K.1
Rouholamini Najafabadi, A.2
Barghi, M.3
Rafiee-Tehrani, M.4
-
17
-
-
0036632415
-
Preparation of dry powder dispersions for non-viral gene delivery by freeze-drying and spray-drying
-
Seville PC, Kellaway IW, Birchall JC. Preparation of dry powder dispersions for non-viral gene delivery by freeze-drying and spray-drying. J. Gene Med., 4, 428-437 (2002).
-
(2002)
J. Gene Med.
, vol.4
, pp. 428-437
-
-
Seville, P.C.1
Kellaway, I.W.2
Birchall, J.C.3
-
18
-
-
0037355596
-
The effect of protective agents on the stability of plasmid DNA by the process of spray-drying
-
Kuo JH. The effect of protective agents on the stability of plasmid DNA by the process of spray-drying. J. Pharm. Pharmacol., 55, 301-306 (2003).
-
(2003)
J. Pharm. Pharmacol.
, vol.55
, pp. 301-306
-
-
Kuo, J.H.1
-
19
-
-
1042292677
-
Preparation of DNA dry powder for non-viral gene delivery by spray-freeze drying: Effect of protective agents (polyethyleneimine and sugars) on the stability of DNA
-
Kuo JH, Hwang R. Preparation of DNA dry powder for non-viral gene delivery by spray-freeze drying: effect of protective agents (polyethyleneimine and sugars) on the stability of DNA. J. Pharm. Pharmacol., 56, 27-33 (2004).
-
(2004)
J. Pharm. Pharmacol.
, vol.56
, pp. 27-33
-
-
Kuo, J.H.1
Hwang, R.2
-
20
-
-
77952670572
-
Optimized pulmonary gene transfection in mice by spray-freeze dried powder inhalation
-
Mohri K, Okuda T, Mori A, Danjo K, Okamoto H. Optimized pulmonary gene transfection in mice by spray-freeze dried powder inhalation. J. Control. Release, 144, 221-226 (2010).
-
(2010)
J. Control. Release
, vol.144
, pp. 221-226
-
-
Mohri, K.1
Okuda, T.2
Mori, A.3
Danjo, K.4
Okamoto, H.5
-
21
-
-
0028284169
-
The protective effect of free and membrane-bound cryoprotectants during freezing and freeze-drying of liposomes
-
Ausborn M, Schreier H, Brezesinski G, Fabian H, Meyer HW, Nuhn P. The protective effect of free and membrane-bound cryoprotectants during freezing and freeze-drying of liposomes. J. Control. Release, 30, 105-116 (1994).
-
(1994)
J. Control. Release
, vol.30
, pp. 105-116
-
-
Ausborn, M.1
Schreier, H.2
Brezesinski, G.3
Fabian, H.4
Meyer, H.W.5
Nuhn, P.6
-
22
-
-
51449095971
-
Effect of lyophilization and freeze-thawing on the stability of siRNA-liposome complexes
-
Yadava P, Gibbs M, Castro C, Hughes JA. Effect of lyophilization and freeze-thawing on the stability of siRNA-liposome complexes. AAPS PharmSciTech, 9, 335-341 (2008).
-
(2008)
AAPS PharmSciTech
, vol.9
, pp. 335-341
-
-
Yadava, P.1
Gibbs, M.2
Castro, C.3
Hughes, J.A.4
-
23
-
-
42649108387
-
Effect of sugars on storage stability of lyophilized liposome/DNA complexes with high transfection efficiency
-
Maitani Y, Aso Y, Yamada A, Yoshioka S. Effect of sugars on storage stability of lyophilized liposome/DNA complexes with high transfection efficiency. Int. J. Pharm., 356, 69-75 (2008).
-
(2008)
Int. J. Pharm.
, vol.356
, pp. 69-75
-
-
Maitani, Y.1
Aso, Y.2
Yamada, A.3
Yoshioka, S.4
-
24
-
-
0034000572
-
In vivo gene delivery to the liver using novel galactosylated cationic liposomes
-
Kawakami S, Fumoto S, Nishikawa M, Yamashita F, Hashida M. In vivo gene delivery to the liver using novel galactosylated cationic liposomes. Pharm. Res., 17, 306-313 (2000).
-
(2000)
Pharm. Res.
, vol.17
, pp. 306-313
-
-
Kawakami, S.1
Fumoto, S.2
Nishikawa, M.3
Yamashita, F.4
Hashida, M.5
-
25
-
-
17844401203
-
Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: The role of the neutral helper lipid
-
Sakurai F, Nishioka T, Saito H, Baba T, Okuda A, Matsumoto O, Taga T, Yamashita F, Takakura Y, Hashida M. Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: the role of the neutral helper lipid. Gene Ther., 8, 677-686 (2001).
-
(2001)
Gene Ther.
, vol.8
, pp. 677-686
-
-
Sakurai, F.1
Nishioka, T.2
Saito, H.3
Baba, T.4
Okuda, A.5
Matsumoto, O.6
Taga, T.7
Yamashita, F.8
Takakura, Y.9
Hashida, M.10
-
26
-
-
0033995526
-
Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes
-
Kawakami S, Sato A, Nishikawa M, Yamashita F, Hashida M. Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes. Gene Ther., 7, 292-299 (2000).
-
(2000)
Gene Ther.
, vol.7
, pp. 292-299
-
-
Kawakami, S.1
Sato, A.2
Nishikawa, M.3
Yamashita, F.4
Hashida, M.5
-
27
-
-
0033812567
-
A novel apparatus for rat in vivo evaluation of dry powder formulations for pulmonary administration
-
Okamoto H, Aoki M, Danjo K. A novel apparatus for rat in vivo evaluation of dry powder formulations for pulmonary administration. J. Pharm. Sci., 89, 1028-1035 (2000).
-
(2000)
J. Pharm. Sci.
, vol.89
, pp. 1028-1035
-
-
Okamoto, H.1
Aoki, M.2
Danjo, K.3
-
28
-
-
60649098297
-
Dual imaging of pulmonary delivery and gene expression of dry powder inhalant by fluorescence and bioluminescence
-
Mizuno T, Mohri K, Nasu S, Danjo K, Okamoto H. Dual imaging of pulmonary delivery and gene expression of dry powder inhalant by fluorescence and bioluminescence. J. Control. Release, 134, 149-154 (2009).
-
(2009)
J. Control. Release
, vol.134
, pp. 149-154
-
-
Mizuno, T.1
Mohri, K.2
Nasu, S.3
Danjo, K.4
Okamoto, H.5
-
29
-
-
33846395107
-
Uptake characteristics of liposomes by rat alveolar macrophages: Influence of particle size and surface mannose modification
-
Chono S, Tanino T, Seki T, Morimoto K. Uptake characteristics of liposomes by rat alveolar macrophages: influence of particle size and surface mannose modification. J. Pharm. Pharmacol., 59, 75-80 (2007).
-
(2007)
J. Pharm. Pharmacol.
, vol.59
, pp. 75-80
-
-
Chono, S.1
Tanino, T.2
Seki, T.3
Morimoto, K.4
|