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Volumn 27, Issue 4, 2012, Pages 387-413

Studies on genotoxicity and carcinogenicity of antibacterial, antiviral, antimalarial and antifungal drugs

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; ACICLOVIR; AMPICILLIN; AMPRENAVIR; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIMALARIAL AGENT; ANTIVIRUS AGENT; AZITHROMYCIN; CHLORAMPHENICOL; CLOFAZIMINE; CYCLOSERINE; DAPSONE; DELAVIRDINE; ENTECAVIR; ETHIONAMIDE; GRISEOFULVIN; INDINAVIR; ISONIAZID; LAMIVUDINE; METRONIDAZOLE; NEVIRAPINE; NITROFURANTOIN; PYRAZINAMIDE; RIFAMPICIN; STAVUDINE; TERBINAFINE; UNINDEXED DRUG; ZALCITABINE; ZIDOVUDINE;

EID: 84863536272     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/ger094     Document Type: Review
Times cited : (36)

References (77)
  • 5
    • 0242293690 scopus 로고    scopus 로고
    • US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER)
    • US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER). (1997) Guidance for Industry. S1B. Testing for Carcinogenicity of Pharmaceuticals.
    • (1997) Guidance for Industry. S1B. Testing for Carcinogenicity of Pharmaceuticals
  • 7
    • 0035012857 scopus 로고    scopus 로고
    • A review of the genotoxicity of marketed pharmaceuticals
    • DOI 10.1016/S1383-5742(01)00055-2, PII S1383574201000552
    • Snyder, R. D. and Green, J. W. (2001) A review of the genotoxicity of marketed pharmaceuticals. Mutat. Res., 488, 151-169. (Pubitemid 32436429)
    • (2001) Mutation Research - Reviews in Mutation Research , vol.488 , Issue.2 , pp. 151-169
    • Snyder, R.D.1    Green, J.W.2
  • 10
    • 19944372857 scopus 로고    scopus 로고
    • 59th edn. Thomson PDR, Montvale, NJ
    • (2005) Physicians' Desk Reference. 59th edn. Thomson PDR, Montvale, NJ.
    • (2005) Physicians' Desk Reference
  • 11
    • 84870940120 scopus 로고    scopus 로고
    • U.S. National Library of Medicine-Toxnet, Toxicology Data Network. http://www.toxnet.nlm.nih.gov.
    • Toxicology Data Network
  • 12
    • 84863519878 scopus 로고    scopus 로고
    • Some antiviral and antineoplastic drugs, and other pharmaceutical agents
    • International Agency for Research on Cancer
    • International Agency for Research on Cancer. (2000) Some antiviral and antineoplastic drugs, and other pharmaceutical agents. IARC Monogr. Eval. Carcinog. Risks Hum., 76, 47-71.
    • (2000) IARC Monogr. Eval. Carcinog. Risks Hum. , vol.76 , pp. 47-71
  • 13
    • 0037194665 scopus 로고    scopus 로고
    • Comparative analysis of DNA breakage, chromosomal aberrations and apoptosis induced by the anti-herpes purine nucleoside analogues aciclovir, ganciclovir and penciclovir
    • Tomicic, M. T., Bey, E., Wutzler, P., Thust, R. and Kaina, B. (2002) Comparative analysis of DNA breakage, chromosomal aberrations and apoptosis induced by the anti-herpes purine nucleoside analogues aciclovir, ganciclovir and penciclovir. Mutat. Res., 505, 1-11.
    • (2002) Mutat. Res. , vol.505 , pp. 1-11
    • Tomicic, M.T.1    Bey, E.2    Wutzler, P.3    Thust, R.4    Kaina, B.5
  • 14
    • 0023855146 scopus 로고
    • A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures
    • Ishidate, M. Jr., Harnois, M. C. and Sofuni, T. (1988) A comparative analysis of data on the clastogenicity of 951 chemical substances tested in mammalian cell cultures. Mutat. Res., 195, 151-213. (Pubitemid 18066068)
    • (1988) Mutation Research , vol.195 , Issue.2 , pp. 151-213
    • Ishidate Jr., M.1    Harnois, M.C.2    Sofuni, T.3
  • 15
    • 0003459737 scopus 로고
    • International Agency for Research on Cancer. Pharmaceutical Drugs, IARC, Lyon, France
    • International Agency for Research on Cancer. (1990). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 50. Pharmaceutical Drugs, IARC, Lyon, France.
    • (1990) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , vol.50
  • 17
    • 0023493481 scopus 로고
    • Frameshift mutagenesis by chloroquine in Escherichia coli and Salmonella typhimurium
    • Thomas, S. M., Silburn, K. A. and MacPhee, D. G. (1987) Frameshift mutagenesis by chloroquine in Escherichia coli and Salmonella typhimurium. Mutat. Res., 192, 233-237. (Pubitemid 18002291)
    • (1987) Mutation Research , vol.192 , Issue.4 , pp. 233-237
    • Thomas, S.M.1    Silburn, K.A.2    MacPhee, D.G.3
  • 18
    • 0024560465 scopus 로고
    • Influence of the UVR-repair system on the mutagenicity of antiparasitic drugs
    • Espinosa-Aguirre, J. J., Ramirez Santos, J. and Cortinas de Nava, C. (1989) Influence of the UVR-repair system on the mutagenicity of antiparasitic drugs. Mutat. Res., 222, 161-166.
    • (1989) Mutat. Res. , vol.222 , pp. 161-166
    • Espinosa-Aguirre, J.J.1    Ramirez Santos, J.2    Cortinas De Nava, C.3
  • 19
    • 0022965360 scopus 로고    scopus 로고
    • Comparison of the Ames assay and the induction of sister chromatid exchanges: Results with ten pharmaceuticals and five selected agents
    • 198
    • Shubber, E. K., Jacobson-Kram, D. and Williams, J. R. (198) Comparison of the Ames assay and the induction of sister chromatid exchanges: results with ten pharmaceuticals and five selected agents. Cell Biol. Toxicol., 2, 379-399.
    • Cell Biol. Toxicol. , vol.2 , pp. 379-399
    • Shubber, E.K.1    Jacobson-Kram, D.2    Williams, J.R.3
  • 20
    • 0021688019 scopus 로고
    • Mutagenicity examination of several non-steroidal anti-inflammatory drugs in bacterial systems
    • Kadotani, S., Arisawa, M. and Maruyama, H. B. (1984) Mutagenicity examination of several non-steroidal anti-inflammatory drugs in bacterial systems. Mutat. Res., 138, 133-136. (Pubitemid 15178009)
    • (1984) Mutation Research , vol.138 , Issue.2-3 , pp. 133-136
    • Kadotani, S.1    Arisawa, M.2    Maruyama, H.B.3
  • 21
    • 0025077877 scopus 로고
    • The comparative responses of Salmonella typhimurium TA1537 and TA97A to a range of reference mutagens and novel compounds
    • O'Donovan, M. R. (1990) The comparative responses of Salmonella typhimurium TA1537 and TA97A to a range of reference mutagens and novel compounds. Mutagenesis, 5, 267-274.
    • (1990) Mutagenesis , vol.5 , pp. 267-274
    • O'Donovan, M.R.1
  • 22
    • 0021590871 scopus 로고
    • Evaluation of microbial testing methods for the mutagenicity of quinoline and its derivatives
    • Sideropoulos, A. S. and Specht, S. M. (1984) Evaluation of microbial testing methods for the mutagenicity of quinoline and its derivatives. Curr. Microbiol., 11, 59-65.
    • (1984) Curr. Microbiol. , vol.11 , pp. 59-65
    • Sideropoulos, A.S.1    Specht, S.M.2
  • 23
    • 0031726186 scopus 로고    scopus 로고
    • Comparative mutagenic and genotoxic effects of three antimalarial drugs, chloroquine, primaquine and amodiaquine
    • Chatterjee, T., Mukopadhyay, A., Khan, K. A. and Giri, K. (1998) Comparative mutagenic and genotoxic effects of three antimalarial drugs, chloroquine, primaquine and amodiaquine. Mutagenesis, 13, 619-624. (Pubitemid 28523826)
    • (1998) Mutagenesis , vol.13 , Issue.6 , pp. 619-624
    • Chatterjee, T.1    Muhkopadhyay, A.2    Khan, K.A.3    Giri, A.K.4
  • 24
    • 84874189614 scopus 로고    scopus 로고
    • Center for Drug Evaluation and Research
    • FDA, Center for Drug Evaluation and Research. http://www.FDA.gov.cder.
  • 25
    • 0021883903 scopus 로고
    • Mutagenicity of N-acetyl and N,N'-diacetyl derivatives of 3 aromatic amines used as epoxy-resin hardeners
    • Tanaka, K., Ino, T., Sawahata, T., Marui, S., Igaki, H. and Yashima, H. (1985) Mutagenicity of N-acetyl and N, N′-diacetyl derivatives of 3 aromatic amines used as epoxy-resin hardeners. Mutat. Res., 143, 11-15. (Pubitemid 15005780)
    • (1985) Mutation Research , vol.143 , Issue.1-2 , pp. 11-15
    • Tanaka, K.1    Ino, T.2    Sawahata, T.3
  • 26
    • 0142036542 scopus 로고
    • Mutagenicity assessment in 44 epoxy resin hardeners in Salmonella typhimurium tester strains
    • Takahashi, A. and Ono, H. (1993) Mutagenicity assessment in 44 epoxy resin hardeners in Salmonella typhimurium tester strains. Chem. Exp., 8, 785-788.
    • (1993) Chem. Exp. , vol.8 , pp. 785-788
    • Takahashi, A.1    Ono, H.2
  • 27
    • 84863530371 scopus 로고
    • Some pharmaceutical drugs
    • IARC
    • IARC. (1980) Some pharmaceutical drugs. IARC Monogr. Eval. Carcinog. Risk Hum., 24, 59-76.
    • (1980) IARC Monogr. Eval. Carcinog. Risk Hum. , vol.24 , pp. 59-76
  • 28
    • 0022330775 scopus 로고
    • Reproducibility of microbial mutagenicity assays: II. Testing of carcinogens and noncarcinogens in Salmonella thyphimurium and Escherichia coli
    • Dunkel, V. C., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H. S. and Simmon, V. F. (1985) Reproducibility of microbial mutagenicity assays: II. Testing of carcinogens and noncarcinogens in Salmonella thyphimurium and Escherichia coli. Environ. Mol. Mutagen., 7 (Suppl. 5), 1-248.
    • (1985) Environ. Mol. Mutagen. , vol.7 , Issue.SUPPL. 5 , pp. 1-248
    • Dunkel, V.C.1    Zeiger, E.2    Brusick, D.3    McCoy, E.4    McGregor, D.5    Mortelmans, K.6    Rosenkranz, H.S.7    Simmon, V.F.8
  • 29
    • 84863515717 scopus 로고
    • NCI/NTP. National Cancer Institute/National Toxicology Program; U.S. Department of Health and Human Services, TR-20
    • NCI/NTP. (1977) Carcinogenesis Technical Report Series; National Cancer Institute/National Toxicology Program; U.S. Department of Health and Human Services, TR-20.
    • (1977) Carcinogenesis Technical Report Series
  • 30
    • 0021257162 scopus 로고
    • Splenic fibrosis and sarcomas in F344 rats fed diets containing aniline hydrochloride, p-chloroaniline, azobenzene, o-toluidine hydrochloride, 4,4'-sulfonyldianiline, or D & C red No. 9
    • Goodman, D. G., Ward, J. M. and Reichardt, W. D. (1984) Splenic fibrosis and sarcomas in F344 rats fed diets containing aniline hydrochloride, p-chloroaniline, azobenzene, o-toluidine hydrochloride, 4,4′- sulfonyldianiline, or D & C red No. 9. J. Natl Cancer Inst., 73, 265-273. (Pubitemid 14090855)
    • (1984) Journal of the National Cancer Institute , vol.73 , Issue.1 , pp. 265-273
    • Goodman, D.G.1    Ward, J.M.2    Reichardt, W.D.3
  • 31
    • 59449086578 scopus 로고
    • Evaluation of mutagenicity of ethambutol hydrochloride using Ames test
    • Shaheen, S. and Rao, M. S. (1990) Evaluation of mutagenicity of ethambutol hydrochloride using Ames test. Trends Life Sci., 5, 7-9.
    • (1990) Trends Life Sci. , vol.5 , pp. 7-9
    • Shaheen, S.1    Rao, M.S.2
  • 32
    • 0025352906 scopus 로고
    • The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency Gene-Tox Program
    • Mavournin, K. H., Blakey, D. H., Cimino, M. C., Salamone, M. F. and Heddle, J. H. (1990) The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 239, 29-80.
    • (1990) Mutat. Res. , vol.239 , pp. 29-80
    • Mavournin, K.H.1    Blakey, D.H.2    Cimino, M.C.3    Salamone, M.F.4    Heddle, J.H.5
  • 33
    • 0023704076 scopus 로고
    • Salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals
    • Zeiger, E., Anderson, B., Haworth, S., Lawlor, T. and Mortelmans, K. (1988) Salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals. Environ. Mol. Mutagen., 11 (Suppl. 12), 1-158.
    • (1988) Environ. Mol. Mutagen. , vol.11 , Issue.SUPPL. 12 , pp. 1-158
    • Zeiger, E.1    Anderson, B.2    Haworth, S.3    Lawlor, T.4    Mortelmans, K.5
  • 34
    • 84916143058 scopus 로고
    • NCI/NTP. National Cancer Institute/National Toxicology Program; US Department of Health and Human Services, TR-46
    • NCI/NTP. (1978) Carcinogenesis Technical Report Series; National Cancer Institute/National Toxicology Program; US Department of Health and Human Services, TR-46.
    • (1978) Carcinogenesis Technical Report Series
  • 35
    • 0031831669 scopus 로고    scopus 로고
    • Chromosome aberrations in vitro related to cytotoxicity of nonmutagenic chemicals and metabolic poisons
    • DOI 10.1002/(SICI)1098-2280(1998)31:4<316::AID-EM3>3.0.CO;2-G
    • Hilliard, C. A., Armstrong, M. J., Bradt, C. I., Hill, R. B., Greenwood, S. K. and Galloway, S. M. (1998) Chromosome aberrations in vitro related to cytotoxicity of nonmutagenic chemicals and metabolic poisons. Environ. Mol. Mutagen., 31, 316-326. (Pubitemid 28308461)
    • (1998) Environmental and Molecular Mutagenesis , vol.31 , Issue.4 , pp. 316-326
    • Hilliard, C.A.1    Armstrong, M.J.2    Bradt, C.I.3    Hill, R.B.4    Greenwood, S.K.5    Galloway, S.M.6
  • 37
    • 84863513794 scopus 로고
    • International Agency for Research on Cancer. Some Miscellaneous Pharmaceutical Substances. IARC, Lyon, France
    • International Agency for Research on Cancer. (1977). IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man, Vol. 13. Some Miscellaneous Pharmaceutical Substances. IARC, Lyon, France, pp. 83-89.
    • (1977) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man , vol.13 , pp. 83-89
  • 38
    • 0011531579 scopus 로고    scopus 로고
    • International Agency for Research on Cancer. Some Thyrotropic Agents, IARC, Lyon, France
    • International Agency for Research on Cancer. (2001). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 79. Some Thyrotropic Agents, IARC, Lyon, France, pp. 291-315.
    • (2001) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , vol.79 , pp. 291-315
  • 39
    • 0023034964 scopus 로고
    • The Salmonella typhimurium mammalian microsomal assay. A report of the U.S. Environmental Protection Agency Gene-Tox Program
    • Kier, L. E., Brusik, D. J., Auletta, A. E. et al. (1986) The Salmonella typhimurium mammalian microsomal assay. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 168, 9-240.
    • (1986) Mutat. Res. , vol.168 , pp. 9-240
    • Kier, L.E.1    Brusik, D.J.2    Auletta, A.E.3
  • 40
    • 0026503111 scopus 로고
    • Salmonella mutagenicity tests. V. Results from the testing of 311 chemicals
    • Zeiger, E., Anderson, B., Haworth, S., Lawlor, T. and Mortelmans, K. (1992) Salmonella mutagenicity tests. V. Results from the testing of 311 chemicals. Environ. Mol. Mutagen., 18 (Suppl. 21), 2-141.
    • (1992) Environ. Mol. Mutagen. , vol.18 , Issue.SUPPL. 21 , pp. 2-141
    • Zeiger, E.1    Anderson, B.2    Haworth, S.3    Lawlor, T.4    Mortelmans, K.5
  • 41
    • 0021267081 scopus 로고
    • Testing of chemicals for genetic activity with Saccharomyces cerevisiae: A report of the US Environmental Protection Agency Gene-Tox Program
    • Zimermann, F. K., Von Borstel, R. C., Von Halle, E. S., Parry, J. M., Siebert, D., Zetterberg, G., Barale, R. and Loprieno, N. (1984) Testing of chemicals for genetic activity with Saccharomyces cerevisiae: a report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 133, 199-244. (Pubitemid 14105533)
    • (1984) Mutation Research , vol.133 , Issue.3 , pp. 199-244
    • Zimmermann, F.K.1    Von Borstel, R.C.2    Von Halle, E.S.3
  • 42
    • 49049133783 scopus 로고
    • Aspergillus nidulans: Systems and results of tests for chemical induction of mitotic segregation and mutation. I. Diploid and duplication assay systems
    • Käfer, E., Scott, B. R., Dorn, G. L. and Stafford, R. (1982) Aspergillus nidulans: systems and results of tests for chemical induction of mitotic segregation and mutation. I. Diploid and duplication assay systems. A report of the U.S. EPA Gene-Tox Program. Mutat. Res., 98, 1-48. (Pubitemid 12163274)
    • (1982) Mutation Research , vol.98 , Issue.1 , pp. 1-48
    • Kafer, E.1    Scott, B.R.2    Dorn, G.L.3    Stafford, R.4
  • 43
    • 0019918283 scopus 로고
    • Chromosome aberrations assays in Allium. A report of the U.S. Environmental Protection Agency Gene-Tox Program
    • Grant, W. F. (1982) Chromosome aberrations assays in Allium. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 99, 273-291.
    • (1982) Mutat. Res. , vol.99 , pp. 273-291
    • Grant, W.F.1
  • 44
    • 8944224535 scopus 로고    scopus 로고
    • Detection of in vitro clastogens and spindle poisons by the mouse lymphoma assay using the microwell method: Interim report of an international collaborative study
    • DOI 10.1093/mutage/11.4.349
    • Sofuni, T., Honma, M., Hayashi, M. et al. (1996) Detection of in vitro clastogenic and spindle poisons by the mouse lymphoma assay using the microwell method: interim report of an international collaborative study. Mutagenesis, 11, 349-355. (Pubitemid 26235486)
    • (1996) Mutagenesis , vol.11 , Issue.4 , pp. 349-355
    • Sofuni, T.1    Honma, M.2    Hayashi, M.3    Shimada, H.4    Tanaka, N.5    Wakuri, S.6    Awogi, T.7    Yamamoto, K.I.8    Nishi, Y.9    Nakadate, M.10
  • 45
    • 0037182151 scopus 로고    scopus 로고
    • A protocol for the in vitro micronucleus test: I. Contributions to the development of a protocol suitable for regulatory submissions from an examination of 16 chemicals with different mechanisms of action and different levels of activity
    • DOI 10.1016/S1383-5718(02)00059-1, PII S1383571802000591
    • Garriott, M. L., Phelps, J. B. and Hoffman, W. P. (2002) A protocol for the in vitro micronucleus test. I. Contributions to the development of a protocol suitable for regulatory submissions from an examination of 16 chemicals with different mechanisms of action and different levels of activity. Mutat. Res., 517, 123-134. (Pubitemid 34597012)
    • (2002) Mutation Research - Genetic Toxicology and Environmental Mutagenesis , vol.517 , Issue.1-2 , pp. 123-134
    • Garriott, M.L.1    Barry, P.J.2    Hoffman, W.P.3
  • 47
    • 22144459783 scopus 로고    scopus 로고
    • Detection of numerical chromosomal aberrations by flow cytometry: A novel process for identifying aneugenic agents
    • Muehlbauer, P. A. Q. and Schuler, M. J. (2005) Detection of numerical chromosomal aberrations by flow cytometry: a novel process for identifying aneugenic agents. Mutat. Res., 585, 156-169.
    • (2005) Mutat. Res. , vol.585 , pp. 156-169
    • Muehlbauer, P.A.Q.1    Schuler, M.J.2
  • 48
    • 0021145592 scopus 로고
    • Induction of sister-chromatid exchanges in vivo in mice by the mycotoxins sterigmatocystin and griseofulvin
    • Curry, P. T., Reed, R. N., Martini, R. M. and Kitchin, R. M. (1984) Induction of sister-chromatid exchanges in vivo in mice by the mycotoxins sterigmatocystin and griseofulvin. Mutat. Res., 137, 111-115. (Pubitemid 14028709)
    • (1984) Mutation Research , vol.137 , Issue.2-3 , pp. 111-115
    • Curry, P.T.1    Reed, R.N.2    Martino, R.M.3    Kitchin, R.M.4
  • 49
    • 0020622741 scopus 로고
    • An evaluation of the mouse sperm morphology test and other sperm tests in nonhuman mammals: A report of the U.S. Environmental Protection Agency Gene-Tox Program
    • Wyrobek, A. J., Gordon, L. A., Burkhart, J. G., Francis, M. W., Kapp, R. W., Letz, G., Malling, H. V., Topham, J. C. and Whorton, M. D. (1983) An evaluation of the mouse sperm morphology test and other sperm tests in non human mammals. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 115, 1-72. (Pubitemid 13122041)
    • (1983) Mutation Research , vol.115 , Issue.1 , pp. 1-72
    • Wyrobek, A.J.1    Gordon, L.A.2    Burkhart, J.G.3
  • 50
    • 0017221887 scopus 로고
    • International Agency for Research on Cancer. Some Naturally Occurring Substances. IARC, Lyon, France
    • International Agency for Research on Cancer. (1976). IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man, Vol. 10. Some Naturally Occurring Substances. IARC, Lyon, France, pp. 153-161.
    • (1976) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man , vol.10 , pp. 153-161
  • 51
    • 0023264925 scopus 로고
    • Chemical carcinogens. A review and analysis of the literature of selected chemicals and the establishment of the gene-tox carcinogen data base. A report of the U.S. Environmental Protection Agency Gene-Tox program
    • Nesnow, S., Argus, M., Bergman, H. et al. (1986) Chemical carcinogens. A review and analysis of the literature of selected chemicals and the establishment of the Gene-Tox Carcinogen Data Base. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 185, 1-195. (Pubitemid 17215638)
    • (1987) Mutation Research , vol.185 , Issue.1-2 , pp. 1-195
    • Nesnow, S.1    Argus, M.2    Bergman, H.3
  • 52
    • 0021158961 scopus 로고
    • Genetic effects of isoniazid and the relationship to in vivo and in vitro biotransformation
    • Braun, R., Jäkel, H.-P. and Schöneich, J. (1984) Genetic effects of isoniazid and the relationship to in vivo and in vitro biotransformation. Mutat. Res., 137, 61-69.
    • (1984) Mutat. Res. , vol.137 , pp. 61-69
    • Braun, R.1    Jäkel, H.-P.2    Schöneich, J.3
  • 53
    • 49049135145 scopus 로고
    • An evaluation of the host-mediated assay and body fluid analysis. A report of the U.S. Environmental Protection Agency gene-tox program
    • Legator, M. S., Bueding, E., Batzinger, R. et al. (1982) An evaluation of the host-mediated assay and body fluid analysis. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 98, 319-374. (Pubitemid 12074502)
    • (1982) Mutation Research , vol.98 , Issue.3 , pp. 319-374
    • Legator, M.S.1    Bueding, E.2    Batzinger, R.3
  • 54
    • 0019518609 scopus 로고
    • Use of the mouse spot test in chemical mutagenesis: Interpretation of past data and recommendations for future work
    • Russel, L. B., Selby, P. B., Von Halle, E., Sheridan, W. and Valcovic, L. (1981) Use of the mouse spot test in chemical mutagenesis: interpretation of past data and recommendation for future work. Mutat. Res., 86, 355-379. (Pubitemid 11063721)
    • (1981) Mutation Research , vol.86 , Issue.3 , pp. 355-379
    • Russell, L.B.1    Selby, P.B.2    Von Halle, E.3
  • 55
    • 0019483223 scopus 로고
    • Sister-chromatid exchanges: A report of the GENE-TOX Program
    • Latt, S. A., Allen, J., Bloom, S. E. et al. (1981) Sister-chromatid exchanges. A report of the Gene-Tox Program. Mutat. Res., 87, 17-62. (Pubitemid 11042443)
    • (1981) Mutation Research , vol.87 , Issue.1 , pp. 17-62
    • Latt, S.A.1    Allen, J.2    Bloom, S.E.3
  • 56
    • 0021845525 scopus 로고
    • Current status of bioassays in genetic toxicology - The dominant lethal assay. A report of the U.S. Environmental Protection Agency Gene-Tox Program
    • Green, S., Auletta, A., Fabricant, J., Kapp, R., Marrandhar, M., Sheu, C., Springer, J. and Whitefield, B. (1985) Current status of bioassays in genetic toxicology - the dominant lethal test. A report of the U.S. Environmental Protection Agency Gene-Tox program. Mutat. Res., 154, 49-67. (Pubitemid 15039544)
    • (1985) Mutation Research , vol.154 , Issue.1 , pp. 49-67
    • Green, S.1    Auletta, A.2    Fabricant, J.3
  • 58
    • 84872379383 scopus 로고
    • Some aromatic amines, hydrazine and related substances, N-nitroso compounds and miscellaneous alkylating agents
    • International Agency for Research on Cancer. IARC, Lyon, France
    • International Agency for Research on Cancer. (1974). IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man, Vol. 4. Some aromatic amines, hydrazine and related substances, N-nitroso compounds and miscellaneous alkylating agents. IARC, Lyon, France, pp. 159-172.
    • (1974) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man , vol.4 , pp. 159-172
  • 60
    • 0023250909 scopus 로고
    • Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals
    • Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., Mortelmans, K. and Speck, W. (1987) Salmonella mutagenicity tests: III. Results from the testing of 255 chemicals. Environ. Mol. Mutagen., 9 (Suppl. 9), 1-110. (Pubitemid 17115119)
    • (1987) Environmental Mutagenesis , vol.9 , Issue.SUPPL. 9 , pp. 1-110
    • Zeiger, E.1    Anderson, B.2    Haworth, S.3
  • 61
    • 84916143058 scopus 로고
    • NCI/NTP National Cancer Institute/National Toxicology Program; US Department of Health and Human Services, TR-48.
    • NCI/NTP (1978) Carcinogenesis Technical Report Series; National Cancer Institute/National Toxicology Program; US Department of Health and Human Services, TR-48.
    • (1978) Carcinogenesis Technical Report Series
  • 62
    • 0019839464 scopus 로고
    • An evaluation of tests using DNA repair-deficient bacteria for predicting genotoxicity and carcinogenicity. A report of the U.S. EPA's Gene-Tox Program
    • Leifer, Z., Tikada, T., Mandel, M., Zeiger, E., Stafford, R. and Rosenkranz, H. S. (1981) An evaluation of tests using DNA repair-deficient bacteria for predicting genotoxicity and carcinogenicity. A report of the U.S. EPA's Gene-Tox Program. Mutat. Res., 87, 211-297. (Pubitemid 12207743)
    • (1981) Mutation Research , vol.87 , Issue.3 , pp. 211-297
    • Leifer, Z.1    Kada, T.2    Mandel, M.3
  • 63
    • 0021042686 scopus 로고
    • Salmonella mutagenicity test results for 250 chemicals
    • DOI 10.1002/em.2860050703
    • Haworth, S., Lawlor, T., Mortelmans, K., Speck, W. and Zeiger, E. (1983) Salmonella mutagenicity test results for 250 chemicals. Environ. Mutagen., 5, 3-142. (Pubitemid 14168891)
    • (1983) Environmental Mutagenesis , vol.5 , Issue.SUPPL. 1 , pp. 3-142
    • Haworth, S.1    Lawlor, T.2    Mortelmans, K.3
  • 64
    • 0033673434 scopus 로고    scopus 로고
    • Comparison of the sensitivities of Salmonella typhimurium strains TA102 and TA 2638A to 16 mutagens
    • Ryden, E., Ekstrom, C., Hellmer, L. and Bolcsfoldi, G. (2000) Comparison of the sensitivities of Salmonella typhimurium strains TA102 and TA 2638A to 16 mutagens. Mutagenesis, 15, 495-502.
    • (2000) Mutagenesis , vol.15 , pp. 495-502
    • Ryden, E.1    Ekstrom, C.2    Hellmer, L.3    Bolcsfoldi, G.4
  • 65
    • 0021705783 scopus 로고
    • Mutagenicity testing with TA97 and TA102 of 30 DNA-damaging compounds, negative with other Salmonella strains
    • De Flora, S., Camoirano, A., Zanacchi, P. and Bennicelli, C. (1984) Mutagenicity testing with Salmonella typhimurium strains TA97 and TA102 of 30 DNA-damaging compounds, negative with other Salmonella strains. Mutat. Res., 134, 159-165. (Pubitemid 15216570)
    • (1984) Mutation Research , vol.134 , Issue.2-3 , pp. 159-165
    • De Flora, S.1    Camoirano, A.2    Zanacchi, P.3    Bennicelli, C.4
  • 66
    • 0019905149 scopus 로고
    • Vicia cytogenetic tests for environmental mutagens. A report of the U.S. Environmental Protection Agency Gene-Tox Program
    • Ma, T.-H. (1982) Vicia cytogenetic tests for environmental mutagens. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 99, 257-271.
    • (1982) Mutat. Res. , vol.99 , pp. 257-271
    • Ma, T.-H.1
  • 69
    • 0035250772 scopus 로고    scopus 로고
    • Genetic risks of antiviral nucleoside analogues - A survey
    • DOI 10.1016/S0166-3542(00)00139-X, PII S016635420000139X
    • Wutzler, P. and Thust, R. (2001) Genetic risks of antiviral nucleoside analogues - a survey. Antivir. Res., 49, 55-74. (Pubitemid 32206741)
    • (2001) Antiviral Research , vol.49 , Issue.2 , pp. 55-74
    • Wutzler, P.1    Thust, R.2
  • 70
    • 0023239438 scopus 로고
    • Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays
    • Tennant, R. W., Margolin, B. H. et al. (1987) A comprehensive analysis of data on the clastogenicity genesis in rodents from in vitro genetic toxicity assays. Science, 236, 933-941. (Pubitemid 17107941)
    • (1987) Science , vol.236 , Issue.4804 , pp. 933-941
    • Tennant, R.W.1    Margolin, B.H.2    Shelby, M.D.3
  • 71
    • 0025184162 scopus 로고
    • Evaluation of four in vitro genetic toxicity tests for predicting rodent carcinogenicity: Confirming of earlier results with 41 additional chemicals
    • Zeiger, E., Haseman, J. K., Shelby, M. D., Margolin, B. H. and Tennant, R. W. (1990) Evaluation of four in vitro genetic toxicity tests for predicting rodent carcinogenicity: confirmation of earlier results with 41 additional chemicals. Environ. Mol. Mutagen., 16 (Suppl. 18), 1-14. (Pubitemid 20376833)
    • (1990) Environmental and Molecular Mutagenesis , vol.16 , Issue.SUPPL. 18 , pp. 1-14
    • Zeiger, E.1    Haseman, J.K.2    Shelby, M.D.3    Margolin, B.H.4    Tennant, R.W.5
  • 72
    • 21544473568 scopus 로고    scopus 로고
    • Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens: I. Sensitivity, specificity and relative predictivity
    • DOI 10.1016/j.mrgentox.2005.02.004, PII S1383571805000835
    • Kirkland, D., Aardema, M., Henderson, L. and Muller, L. (2005) Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens. I. Sensitivity, specificity and relative predictivity. Mutat. Res., 584, 1-256. (Pubitemid 40922793)
    • (2005) Mutation Research - Genetic Toxicology and Environmental Mutagenesis , vol.584 , Issue.1-2 , pp. 1-256
    • Kirkland, D.1    Aardema, M.2    Henderson, L.3    Muller, L.4
  • 76
    • 47849089737 scopus 로고    scopus 로고
    • Evaluation of the ability of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens. III. Appropriate follow-up testing in vivo
    • Kirkland, D. and Speit, G. (2008) Evaluation of the ability of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens. III. Appropriate follow-up testing in vivo. Mutat. Res., 654, 114-132.
    • (2008) Mutat. Res. , vol.654 , pp. 114-132
    • Kirkland, D.1    Speit, G.2
  • 77
    • 33947600311 scopus 로고    scopus 로고
    • Genotoxic and carcinogenic risk to humans of drug-nitrite interaction products
    • DOI 10.1016/j.mrrev.2006.09.003, PII S1383574206000937
    • Brambilla, G. and Martelli, A. (2007) Genotoxic and carcinogenic risk to humans of drug-nitrite interaction products. Mutat. Res., 635, 17-52. (Pubitemid 46482377)
    • (2007) Mutation Research - Reviews in Mutation Research , vol.635 , Issue.1 , pp. 17-52
    • Brambilla, G.1    Martelli, A.2


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