-
3
-
-
5044232017
-
Liver regeneration: from myth to mechanism
-
Taub R. Liver regeneration: from myth to mechanism. Nat Rev Mol Cell Biol 2004; 5: 836-47.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 836-847
-
-
Taub, R.1
-
4
-
-
58449135983
-
Stem cells in liver regeneration, fibrosis and cancer: the good, the bad and the ugly
-
Alison MR, Islam S, Lim S. Stem cells in liver regeneration, fibrosis and cancer: the good, the bad and the ugly. J Pathol 2009; 217: 282-98.
-
(2009)
J Pathol
, vol.217
, pp. 282-298
-
-
Alison, M.R.1
Islam, S.2
Lim, S.3
-
5
-
-
0032442852
-
Smads: transcriptional activators of TGF-beta responses
-
Derynck R, Zhang Y, Feng XH. Smads: transcriptional activators of TGF-beta responses. Cell 1998; 95: 737-40.
-
(1998)
Cell
, vol.95
, pp. 737-740
-
-
Derynck, R.1
Zhang, Y.2
Feng, X.H.3
-
6
-
-
0037204990
-
Signal transduction by the TGF-beta superfamily
-
Attisano L, Wrana JL. Signal transduction by the TGF-beta superfamily. Science 2002; 296: 1646-7.
-
(2002)
Science
, vol.296
, pp. 1646-1647
-
-
Attisano, L.1
Wrana, J.L.2
-
7
-
-
0024040124
-
Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat
-
Russell WE, Coffey RJ Jr, Ouellette AJ, Moses HL. Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat. Proc Natl Acad Sci USA 1988; 85: 5126-30.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 5126-5130
-
-
Russell, W.E.1
Coffey Jr., R.J.2
Ouellette, A.J.3
Moses, H.L.4
-
8
-
-
33846454667
-
Transforming growth factor-beta differentially regulates oval cell and hepatocyte proliferation
-
Nguyen LN, Furuya MH, Wolfraim LA, et al. Transforming growth factor-beta differentially regulates oval cell and hepatocyte proliferation. Hepatology 2007; 45: 31-41.
-
(2007)
Hepatology
, vol.45
, pp. 31-41
-
-
Nguyen, L.N.1
Furuya, M.H.2
Wolfraim, L.A.3
-
9
-
-
0000742819
-
Transforming growth factor beta mRNA increases during liver regeneration: a possible paracrine mechanism of growth regulation
-
Braun L, Mead JE, Panzica M, et al. Transforming growth factor beta mRNA increases during liver regeneration: a possible paracrine mechanism of growth regulation. Proc Natl Acad Sci USA 1988; 85: 1539-43.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 1539-1543
-
-
Braun, L.1
Mead, J.E.2
Panzica, M.3
-
10
-
-
0037047428
-
Up-regulated transcriptional repressors SnoN and Ski bind Smad proteins to antagonize transforming growth factor-beta signals during liver regeneration
-
Macias-Silva M, Li W, Leu JI, Crissey MA, Taub R. Up-regulated transcriptional repressors SnoN and Ski bind Smad proteins to antagonize transforming growth factor-beta signals during liver regeneration. J Biol Chem 2002; 277: 28483-90.
-
(2002)
J Biol Chem
, vol.277
, pp. 28483-28490
-
-
Macias-Silva, M.1
Li, W.2
Leu, J.I.3
Crissey, M.A.4
Taub, R.5
-
11
-
-
20944441078
-
Inactivation of TGF-beta signaling in hepatocytes results in an increased proliferative response after partial hepatectomy
-
Romero-Gallo J, Sozmen EG, Chytil A, et al. Inactivation of TGF-beta signaling in hepatocytes results in an increased proliferative response after partial hepatectomy. Oncogene 2005; 24: 3028-41.
-
(2005)
Oncogene
, vol.24
, pp. 3028-3041
-
-
Romero-Gallo, J.1
Sozmen, E.G.2
Chytil, A.3
-
12
-
-
0037462502
-
Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice
-
Tang Y, Katuri V, Dillner A, et al. Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice. Science 2003; 299: 574-7.
-
(2003)
Science
, vol.299
, pp. 574-577
-
-
Tang, Y.1
Katuri, V.2
Dillner, A.3
-
13
-
-
11144299533
-
Loss of cooperative function of transforming growth factor-beta signaling proteins, smad3 with embryonic liver fodrin, a beta-spectrin, in primary biliary cirrhosis
-
Mishra B, Tang Y, Katuri V, et al. Loss of cooperative function of transforming growth factor-beta signaling proteins, smad3 with embryonic liver fodrin, a beta-spectrin, in primary biliary cirrhosis. Liver Int 2004; 24: 637-45.
-
(2004)
Liver Int
, vol.24
, pp. 637-645
-
-
Mishra, B.1
Tang, Y.2
Katuri, V.3
-
14
-
-
24644458638
-
The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer
-
Mishra L, Shetty K, Tang Y, Stuart A, Byers SW. The role of TGF-beta and Wnt signaling in gastrointestinal stem cells and cancer. Oncogene 2005; 24: 5775-89.
-
(2005)
Oncogene
, vol.24
, pp. 5775-5789
-
-
Mishra, L.1
Shetty, K.2
Tang, Y.3
Stuart, A.4
Byers, S.W.5
-
15
-
-
12444265695
-
Orofacial and gastrointestinal hyperplasia and neoplasia in smad4 + /- and elf+/-/smad4 + /- mutant mice
-
Redman RS, Katuri V, Tang Y, et al. Orofacial and gastrointestinal hyperplasia and neoplasia in smad4 + /- and elf+/-/smad4 + /- mutant mice. J Oral Pathol Med 2005; 34: 23-9.
-
(2005)
J Oral Pathol Med
, vol.34
, pp. 23-29
-
-
Redman, R.S.1
Katuri, V.2
Tang, Y.3
-
16
-
-
20144378766
-
Transforming growth factor-beta suppresses nonmetastatic colon cancer through Smad4 and adaptor protein ELF at an early stage of tumorigenesis
-
Tang Y, Katuri V, Srinivasan R, et al. Transforming growth factor-beta suppresses nonmetastatic colon cancer through Smad4 and adaptor protein ELF at an early stage of tumorigenesis. Cancer Res 2005; 65: 4228-37.
-
(2005)
Cancer Res
, vol.65
, pp. 4228-4237
-
-
Tang, Y.1
Katuri, V.2
Srinivasan, R.3
-
17
-
-
33745639683
-
Inactivation of TGF-beta signaling in lung cancer results in increased CDK4 activity that can be rescued by ELF
-
Baek HJ, Kim SS, da Silva FM, et al. Inactivation of TGF-beta signaling in lung cancer results in increased CDK4 activity that can be rescued by ELF. Biochem Biophys Res Commun 2006; 346: 1150-7.
-
(2006)
Biochem Biophys Res Commun
, vol.346
, pp. 1150-1157
-
-
Baek, H.J.1
Kim, S.S.2
da Silva, F.M.3
-
18
-
-
35848951652
-
Disruption of transforming growth factor-beta signaling through beta-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation
-
Kitisin K, Ganesan N, Tang Y, et al. Disruption of transforming growth factor-beta signaling through beta-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation. Oncogene 2007; 26: 7103-10.
-
(2007)
Oncogene
, vol.26
, pp. 7103-7110
-
-
Kitisin, K.1
Ganesan, N.2
Tang, Y.3
-
19
-
-
54449089923
-
Hepatocellular cancer arises from loss of transforming growth factor beta signaling adaptor protein embryonic liver fodrin through abnormal angiogenesis
-
Baek HJ, Lim SC, Kitisin K, et al. Hepatocellular cancer arises from loss of transforming growth factor beta signaling adaptor protein embryonic liver fodrin through abnormal angiogenesis. Hepatology 2008; 48: 1128-37.
-
(2008)
Hepatology
, vol.48
, pp. 1128-1137
-
-
Baek, H.J.1
Lim, S.C.2
Kitisin, K.3
-
20
-
-
40649116943
-
Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling
-
Tang Y, Kitisin K, Jogunoori W, et al. Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling. Proc Natl Acad Sci USA 2008; 105: 2445-50.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 2445-2450
-
-
Tang, Y.1
Kitisin, K.2
Jogunoori, W.3
-
21
-
-
84855162699
-
Embryonic liver fodrin involved in stellate cell activation and formation of regenerative nodule in liver cirrhosis
-
Wang Z, Liu F, Tu W, et al. Embryonic liver fodrin involved in stellate cell activation and formation of regenerative nodule in liver cirrhosis. J Cell Mol Med 2012; 16: 118-28.
-
(2012)
J Cell Mol Med
, vol.16
, pp. 118-128
-
-
Wang, Z.1
Liu, F.2
Tu, W.3
-
22
-
-
50249150340
-
A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice
-
Mitchell C, Willenbring H. A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice. Nat Protoc 2008; 3: 1167-70.
-
(2008)
Nat Protoc
, vol.3
, pp. 1167-1170
-
-
Mitchell, C.1
Willenbring, H.2
-
23
-
-
0033552955
-
Elf3 encodes a novel 200-kD beta-spectrin: role in liver development
-
Mishra L, Cai T, Yu P, Monga SP, Mishra B. Elf3 encodes a novel 200-kD beta-spectrin: role in liver development. Oncogene 1999; 18: 353-64.
-
(1999)
Oncogene
, vol.18
, pp. 353-364
-
-
Mishra, L.1
Cai, T.2
Yu, P.3
Monga, S.P.4
Mishra, B.5
-
24
-
-
0027979778
-
Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha
-
Wu JC, Merlino G, Fausto N. Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha. Proc Natl Acad Sci USA 1994; 91: 674-8.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 674-678
-
-
Wu, J.C.1
Merlino, G.2
Fausto, N.3
-
25
-
-
48249122445
-
PI3K/Akt activation is critical for early hepatic regeneration after partial hepatectomy
-
Jackson LN, Larson SD, Silva SR, et al. PI3K/Akt activation is critical for early hepatic regeneration after partial hepatectomy. Am J Physiol Gastrointest Liver Physiol 2008; 294: G1401-10.
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
-
-
Jackson, L.N.1
Larson, S.D.2
Silva, S.R.3
-
26
-
-
2342471301
-
Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis
-
Conery AR, Cao Y, Thompson EA, et al. Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis. Nat Cell Biol 2004; 6: 366-72.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 366-372
-
-
Conery, A.R.1
Cao, Y.2
Thompson, E.A.3
-
27
-
-
2342647439
-
PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3
-
Remy I, Montmarquette A, Michnick SW. PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3. Nat Cell Biol 2004; 6: 358-65.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 358-365
-
-
Remy, I.1
Montmarquette, A.2
Michnick, S.W.3
-
28
-
-
78651415150
-
The role of stem cells in liver repair and fibrosis
-
Greenbaum LE, Wells RG. The role of stem cells in liver repair and fibrosis. Int J Biochem Cell Biol 2011; 43: 222-9.
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 222-229
-
-
Greenbaum, L.E.1
Wells, R.G.2
-
29
-
-
0035223843
-
Anti-transforming growth factor-beta1 antibody transiently enhances DNA synthesis during liver regeneration after partial hepatectomy in rats
-
Enami Y, Kato H, Murakami M, et al. Anti-transforming growth factor-beta1 antibody transiently enhances DNA synthesis during liver regeneration after partial hepatectomy in rats. J Hepatobiliary Pancreat Surg 2001; 8: 250-8.
-
(2001)
J Hepatobiliary Pancreat Surg
, vol.8
, pp. 250-258
-
-
Enami, Y.1
Kato, H.2
Murakami, M.3
-
30
-
-
77950602936
-
Role of transforming growth factor beta signaling and expansion of progenitor cells in regenerating liver
-
Thenappan A, Li Y, Kitisin K, et al. Role of transforming growth factor beta signaling and expansion of progenitor cells in regenerating liver. Hepatology 2011; 51: 1373-82.
-
(2011)
Hepatology
, vol.51
, pp. 1373-1382
-
-
Thenappan, A.1
Li, Y.2
Kitisin, K.3
-
31
-
-
79955083101
-
Loss of transforming growth factor beta adaptor protein beta-2 spectrin leads to delayed liver regeneration in mice
-
Thenappan A, Shukla V, Abdul Khalek FJ, et al. Loss of transforming growth factor beta adaptor protein beta-2 spectrin leads to delayed liver regeneration in mice. Hepatology 2011; 53: 1641-50.
-
(2011)
Hepatology
, vol.53
, pp. 1641-1650
-
-
Thenappan, A.1
Shukla, V.2
Abdul Khalek, F.J.3
-
32
-
-
79955083102
-
Transforming growth factor-beta adaptor, beta2-spectrin, modulates cyclin dependent kinase 4 to reduce development of hepatocellular cancer
-
Baek HJ, Pishvaian MJ, Tang Y, et al. Transforming growth factor-beta adaptor, beta2-spectrin, modulates cyclin dependent kinase 4 to reduce development of hepatocellular cancer. Hepatology 2011; 53: 1676-84.
-
(2011)
Hepatology
, vol.53
, pp. 1676-1684
-
-
Baek, H.J.1
Pishvaian, M.J.2
Tang, Y.3
-
33
-
-
33646470279
-
TGF-beta signaling pathway inactivation and cell cycle deregulation in the development of gastric cancer: role of the beta-spectrin, ELF
-
Kim SS, Shetty K, Katuri V, et al. TGF-beta signaling pathway inactivation and cell cycle deregulation in the development of gastric cancer: role of the beta-spectrin, ELF. Biochem Biophys Res Commun 2006; 344: 1216-23.
-
(2006)
Biochem Biophys Res Commun
, vol.344
, pp. 1216-1223
-
-
Kim, S.S.1
Shetty, K.2
Katuri, V.3
-
34
-
-
58149213801
-
Non-Smad pathways in TGF-beta signaling
-
Zhang YE. Non-Smad pathways in TGF-beta signaling. Cell Res 2009; 19: 128-39.
-
(2009)
Cell Res
, vol.19
, pp. 128-139
-
-
Zhang, Y.E.1
-
35
-
-
51349133312
-
Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways
-
Nitta T, Kim JS, Mohuczy D, Behrns KE. Murine cirrhosis induces hepatocyte epithelial mesenchymal transition and alterations in survival signaling pathways. Hepatology 2008; 48: 909-19.
-
(2008)
Hepatology
, vol.48
, pp. 909-919
-
-
Nitta, T.1
Kim, J.S.2
Mohuczy, D.3
Behrns, K.E.4
|