-
1
-
-
77952002277
-
Gastric cancer: a primer on the epidemiology and biology of the disease and an overview of the medical management of advanced disease
-
Shah MA, Kelsen DP. Gastric cancer: a primer on the epidemiology and biology of the disease and an overview of the medical management of advanced disease. J Natl Compr Canc Netw 2010, 8:437-447.
-
(2010)
J Natl Compr Canc Netw
, vol.8
, pp. 437-447
-
-
Shah, M.A.1
Kelsen, D.P.2
-
2
-
-
68249162541
-
Beta-Elemene, a novel plant-derived antineoplastic agent, increases cisplatin chemosensitivity of lung tumor cells by triggering apoptosis
-
Li QQ, Wang G, Zhang M, Cuff CF, Huang L, Reed E. beta-Elemene, a novel plant-derived antineoplastic agent, increases cisplatin chemosensitivity of lung tumor cells by triggering apoptosis. Oncol Rep 2009, 22:161-170.
-
(2009)
Oncol Rep
, vol.22
, pp. 161-170
-
-
Li, Q.Q.1
Wang, G.2
Zhang, M.3
Cuff, C.F.4
Huang, L.5
Reed, E.6
-
3
-
-
18544369255
-
Antitumor effect of beta-elemene in non-small-cell lung cancer cells is mediated via induction of cell cycle arrest and apoptotic cell death
-
10.1007/s00018-005-5017-3, 15868411
-
Wang G, Li X, Huang F, Zhao J, Ding H, Cunningham C, Coad JE, Flynn DC, Reed E, Li QQ. Antitumor effect of beta-elemene in non-small-cell lung cancer cells is mediated via induction of cell cycle arrest and apoptotic cell death. Cell Mol Life Sci 2005, 62:881-893. 10.1007/s00018-005-5017-3, 15868411.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 881-893
-
-
Wang, G.1
Li, X.2
Huang, F.3
Zhao, J.4
Ding, H.5
Cunningham, C.6
Coad, J.E.7
Flynn, D.C.8
Reed, E.9
Li, Q.Q.10
-
4
-
-
70450162214
-
Cell apoptosis induced by delta-elemene in colorectal adenocarcinoma cells via a mitochondrial-mediated pathway
-
10.1248/yakushi.129.1403, 19881213
-
Xie CY, Yang W, Li M, Ying J, Tao SJ, Li K, Dong JH, Wang XS. Cell apoptosis induced by delta-elemene in colorectal adenocarcinoma cells via a mitochondrial-mediated pathway. Yakugaku Zasshi 2009, 129:1403-1413. 10.1248/yakushi.129.1403, 19881213.
-
(2009)
Yakugaku Zasshi
, vol.129
, pp. 1403-1413
-
-
Xie, C.Y.1
Yang, W.2
Li, M.3
Ying, J.4
Tao, S.J.5
Li, K.6
Dong, J.H.7
Wang, X.S.8
-
5
-
-
42649116109
-
Anti-tumor effect of beta-elemene in glioblastoma cells depends on p38 MAPK activation
-
10.1016/j.canlet.2008.01.049, 18442668
-
Yao YQ, Ding X, Jia YC, Huang CX, Wang YZ, Xu YH. Anti-tumor effect of beta-elemene in glioblastoma cells depends on p38 MAPK activation. Cancer Lett 2008, 264:127-134. 10.1016/j.canlet.2008.01.049, 18442668.
-
(2008)
Cancer Lett
, vol.264
, pp. 127-134
-
-
Yao, Y.Q.1
Ding, X.2
Jia, Y.C.3
Huang, C.X.4
Wang, Y.Z.5
Xu, Y.H.6
-
6
-
-
0030274757
-
Phase III clinical trial of elemenum emulsion in the management of malignant pleural and peritoneal effusions
-
Wang J, Zhang H, Sun Y. Phase III clinical trial of elemenum emulsion in the management of malignant pleural and peritoneal effusions. Zhonghua Zhong Liu Za Zhi 1996, 18:464-447.
-
(1996)
Zhonghua Zhong Liu Za Zhi
, vol.18
, pp. 464-1447
-
-
Wang, J.1
Zhang, H.2
Sun, Y.3
-
7
-
-
0034286088
-
Clinical study on treatment of 40 cases of malignant brain tumor by elemene emulsion injection
-
Tan P, Zhong W, Cai W. Clinical study on treatment of 40 cases of malignant brain tumor by elemene emulsion injection. Zhongguo Zhong Xi Yi Jie He Za Zhi 2000, 20:645-648.
-
(2000)
Zhongguo Zhong Xi Yi Jie He Za Zhi
, vol.20
, pp. 645-648
-
-
Tan, P.1
Zhong, W.2
Cai, W.3
-
8
-
-
18544381215
-
Antiproliferative effect of beta-elemene in chemoresistant ovarian carcinoma cells is mediated through arrest of the cell cycle at the G2-M phase
-
10.1007/s00018-005-5027-1, 15868412
-
Li X, Wang G, Zhao J, Ding H, Cunningham C, Chen F, Flynn DC, Reed E, Li QQ. Antiproliferative effect of beta-elemene in chemoresistant ovarian carcinoma cells is mediated through arrest of the cell cycle at the G2-M phase. Cell Mol Life Sci 2005, 62:894-904. 10.1007/s00018-005-5027-1, 15868412.
-
(2005)
Cell Mol Life Sci
, vol.62
, pp. 894-904
-
-
Li, X.1
Wang, G.2
Zhao, J.3
Ding, H.4
Cunningham, C.5
Chen, F.6
Flynn, D.C.7
Reed, E.8
Li, Q.Q.9
-
9
-
-
78649537934
-
Evaluation of Cisplatin in Combination with beta-Elemene as a Regimen for Prostate Cancer Chemotherapy
-
Li QQ, Wang G, Reed E, Huang L, Cuff CF. Evaluation of Cisplatin in Combination with beta-Elemene as a Regimen for Prostate Cancer Chemotherapy. Basic Clin Pharmacol Toxicol 2010,
-
(2010)
Basic Clin Pharmacol Toxicol
-
-
Li, Q.Q.1
Wang, G.2
Reed, E.3
Huang, L.4
Cuff, C.F.5
-
10
-
-
36249025723
-
Autophagy: process and function
-
10.1101/gad.1599207, 18006683
-
Mizushima N. Autophagy: process and function. Genes Dev 2007, 21:2861-2873. 10.1101/gad.1599207, 18006683.
-
(2007)
Genes Dev
, vol.21
, pp. 2861-2873
-
-
Mizushima, N.1
-
11
-
-
27644493346
-
The pleiotropic role of autophagy: From protein metabolism to bactericide
-
Mizushima N. The pleiotropic role of autophagy: From protein metabolism to bactericide. Cell Death Differ 2005, 12:1535-1541.
-
(2005)
Cell Death Differ
, vol.12
, pp. 1535-1541
-
-
Mizushima, N.1
-
12
-
-
34147193472
-
Cell biology: autophagy and cancer
-
10.1038/446745a, 17429391
-
Levine B. Cell biology: autophagy and cancer. Nature 2007, 446:745-747. 10.1038/446745a, 17429391.
-
(2007)
Nature
, vol.446
, pp. 745-747
-
-
Levine, B.1
-
13
-
-
25144506835
-
Autophagy in cell death: an innocent convict?
-
10.1172/JCI26390, 1236698, 16200202
-
Levine B, Yuan J. Autophagy in cell death: an innocent convict?. J Clin Invest 2005, 115:2679-2688. 10.1172/JCI26390, 1236698, 16200202.
-
(2005)
J Clin Invest
, vol.115
, pp. 2679-2688
-
-
Levine, B.1
Yuan, J.2
-
14
-
-
77955038334
-
The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1{alpha} and Bcl-2 and activating the beclin 1/hVps34 complex
-
10.1158/0008-5472.CAN-10-0157, 20634405
-
Li X, Fan Z. The epidermal growth factor receptor antibody cetuximab induces autophagy in cancer cells by downregulating HIF-1{alpha} and Bcl-2 and activating the beclin 1/hVps34 complex. Cancer Res 2010, 70:5942-5952. 10.1158/0008-5472.CAN-10-0157, 20634405.
-
(2010)
Cancer Res
, vol.70
, pp. 5942-5952
-
-
Li, X.1
Fan, Z.2
-
15
-
-
77954556955
-
Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells
-
10.1186/1471-2407-10-370, 2914703, 20630104
-
Sasaki K, Tsuno NH, Sunami E, Tsurita G, Kawai K, Okaji Y, Nishikawa T, Shuno Y, Hongo K, Hiyoshi M, Kaneko M, Kitayama J, Takahashi K, Nagawa H. Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells. BMC Cancer 2010, 10:370. 10.1186/1471-2407-10-370, 2914703, 20630104.
-
(2010)
BMC Cancer
, vol.10
, pp. 370
-
-
Sasaki, K.1
Tsuno, N.H.2
Sunami, E.3
Tsurita, G.4
Kawai, K.5
Okaji, Y.6
Nishikawa, T.7
Shuno, Y.8
Hongo, K.9
Hiyoshi, M.10
Kaneko, M.11
Kitayama, J.12
Takahashi, K.13
Nagawa, H.14
-
16
-
-
33846794896
-
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
-
10.1172/JCI28833, 1765515, 17235397
-
Amaravadi RK, Yu D, Lum JJ, Bui T, Christophorou MA, Evan GI, Thomas-Tikhonenko A, Thompson CB. Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. J Clin Invest 2007, 117:326-336. 10.1172/JCI28833, 1765515, 17235397.
-
(2007)
J Clin Invest
, vol.117
, pp. 326-336
-
-
Amaravadi, R.K.1
Yu, D.2
Lum, J.J.3
Bui, T.4
Christophorou, M.A.5
Evan, G.I.6
Thomas-Tikhonenko, A.7
Thompson, C.B.8
-
17
-
-
77955578557
-
Glucosamine induces autophagic cell death through the stimulation of ER stress in human glioma cancer cells
-
10.1016/j.bbrc.2010.07.050, 20643103
-
Hwang MS, Baek WK. Glucosamine induces autophagic cell death through the stimulation of ER stress in human glioma cancer cells. Biochem Biophys Res Commun 2010, 399:111-6. 10.1016/j.bbrc.2010.07.050, 20643103.
-
(2010)
Biochem Biophys Res Commun
, vol.399
, pp. 111-116
-
-
Hwang, M.S.1
Baek, W.K.2
-
18
-
-
77957660865
-
Dasatinib induces autophagic cell death in human ovarian cancer
-
10.1002/cncr.25426, 20629079
-
Le XF, Mao W, Lu Z, Carter BZ, Bast RC. Dasatinib induces autophagic cell death in human ovarian cancer. Cancer 2010, 116:4980-4990. 10.1002/cncr.25426, 20629079.
-
(2010)
Cancer
, vol.116
, pp. 4980-4990
-
-
Le, X.F.1
Mao, W.2
Lu, Z.3
Carter, B.Z.4
Bast, R.C.5
-
19
-
-
34547624687
-
A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells
-
Park KJ, Lee SH, Kim TI, Lee HW, Lee CH, Kim EH, Jang JY, Choi KS, Kwon MH, Kim YS. A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells. Cancer Res 2007, (67):7327-7334.
-
(2007)
Cancer Res
, Issue.67
, pp. 7327-7334
-
-
Park, K.J.1
Lee, S.H.2
Kim, T.I.3
Lee, H.W.4
Lee, C.H.5
Kim, E.H.6
Jang, J.Y.7
Choi, K.S.8
Kwon, M.H.9
Kim, Y.S.10
-
20
-
-
36249023658
-
Autophagic cell death of human pancreatic tumor cells mediated by oleandrin, a lipid-soluble cardiac glycoside
-
10.1177/1534735407309623, 18048883
-
Newman RA, Kondo Y, Yokoyama T, Dixon S, Cartwright C, Chan D, Johansen M, Yang P. Autophagic cell death of human pancreatic tumor cells mediated by oleandrin, a lipid-soluble cardiac glycoside. Integr Cancer Ther 2007, 6:354-364. 10.1177/1534735407309623, 18048883.
-
(2007)
Integr Cancer Ther
, vol.6
, pp. 354-364
-
-
Newman, R.A.1
Kondo, Y.2
Yokoyama, T.3
Dixon, S.4
Cartwright, C.5
Chan, D.6
Johansen, M.7
Yang, P.8
-
21
-
-
77953988178
-
Triterpenes from Ganoderma Lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK)
-
10.1080/01635580903532390, 20574924
-
Thyagarajan A, Jedinak A, Nguyen H, Terry C, Baldridge LA, Jiang J, Sliva D. Triterpenes from Ganoderma Lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK). Nutr Cancer 2010, 62:630-640. 10.1080/01635580903532390, 20574924.
-
(2010)
Nutr Cancer
, vol.62
, pp. 630-640
-
-
Thyagarajan, A.1
Jedinak, A.2
Nguyen, H.3
Terry, C.4
Baldridge, L.A.5
Jiang, J.6
Sliva, D.7
-
23
-
-
75149175502
-
Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells
-
10.1038/onc.2009.343, 2809784, 19881538
-
Zhu K, Dunner K, McConkey DJ. Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cells. Oncogene 2010, 29:451-462. 10.1038/onc.2009.343, 2809784, 19881538.
-
(2010)
Oncogene
, vol.29
, pp. 451-462
-
-
Zhu, K.1
Dunner, K.2
McConkey, D.J.3
-
24
-
-
33845974091
-
Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling
-
10.1074/jbc.M607094200, 17005556
-
Kim KW, Mutter RW, Cao C, Albert JM, Freeman M, Hallahan DE, Lu B. Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling. J Biol Chem 2006, 281:36883-36890. 10.1074/jbc.M607094200, 17005556.
-
(2006)
J Biol Chem
, vol.281
, pp. 36883-36890
-
-
Kim, K.W.1
Mutter, R.W.2
Cao, C.3
Albert, J.M.4
Freeman, M.5
Hallahan, D.E.6
Lu, B.7
-
25
-
-
0030904561
-
The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal
-
10.1101/gad.11.6.701, 9087425
-
Kennedy SG, Wagner AJ, Conzen SD, Jordán J, Bellacosa A, Tsichlis PN, Hay N. The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. Genes Dev 1997, 11:701-713. 10.1101/gad.11.6.701, 9087425.
-
(1997)
Genes Dev
, vol.11
, pp. 701-713
-
-
Kennedy, S.G.1
Wagner, A.J.2
Conzen, S.D.3
Jordán, J.4
Bellacosa, A.5
Tsichlis, P.N.6
Hay, N.7
-
26
-
-
67649313308
-
Ubiquitin ligase Cbl-b sensitizes leukemia and gastric cancer cells to anthracyclines by activating the mitochondrial pathway and modulating Akt and ERK survival signals
-
10.1016/j.febslet.2009.05.054, 19508871
-
Qu X, Zhang Y, Li Y, Hu X, Xu Y, Xu L, Hou K, Sada K, Liu Y. Ubiquitin ligase Cbl-b sensitizes leukemia and gastric cancer cells to anthracyclines by activating the mitochondrial pathway and modulating Akt and ERK survival signals. FEBS Lett 2009, 583:2255-2262. 10.1016/j.febslet.2009.05.054, 19508871.
-
(2009)
FEBS Lett
, vol.583
, pp. 2255-2262
-
-
Qu, X.1
Zhang, Y.2
Li, Y.3
Hu, X.4
Xu, Y.5
Xu, L.6
Hou, K.7
Sada, K.8
Liu, Y.9
-
27
-
-
70350747789
-
Gastric cancer exosomes promote tumour cell proliferation through PI3K/Akt and MAPK/ERK activation
-
10.1016/j.dld.2009.04.006, 19473897
-
Qu JL, Qu XJ, Zhao MF, Teng YE, Zhang Y, Hou KZ, Jiang YH, Yang XH, Liu YP. Gastric cancer exosomes promote tumour cell proliferation through PI3K/Akt and MAPK/ERK activation. Dig Liver Dis 2009, 41:875-880. 10.1016/j.dld.2009.04.006, 19473897.
-
(2009)
Dig Liver Dis
, vol.41
, pp. 875-880
-
-
Qu, J.L.1
Qu, X.J.2
Zhao, M.F.3
Teng, Y.E.4
Zhang, Y.5
Hou, K.Z.6
Jiang, Y.H.7
Yang, X.H.8
Liu, Y.P.9
-
28
-
-
77954424770
-
Cbl-b promotes chemotherapy-induced apoptosis in rat basophilic leukemia cells by suppressing PI3K/Akt activation and enhancing MEK/ERK activation
-
10.1007/s11010-010-0407-8, 20177738
-
Qu X, Li Y, Liu J, Xu L, Zhang Y, Hu X, Hou K, Liu Y. Cbl-b promotes chemotherapy-induced apoptosis in rat basophilic leukemia cells by suppressing PI3K/Akt activation and enhancing MEK/ERK activation. Mol Cell Biochem 2010, 340:107-114. 10.1007/s11010-010-0407-8, 20177738.
-
(2010)
Mol Cell Biochem
, vol.340
, pp. 107-114
-
-
Qu, X.1
Li, Y.2
Liu, J.3
Xu, L.4
Zhang, Y.5
Hu, X.6
Hou, K.7
Liu, Y.8
-
29
-
-
1642471831
-
PI3K/Akt and apoptosis: size matters
-
10.1038/sj.onc.1207115, 14663477
-
Franke TF, Hornik CP, Segev L, Shostak GA, Sugimoto C. PI3K/Akt and apoptosis: size matters. Oncogene 2003, 22:8983-8998. 10.1038/sj.onc.1207115, 14663477.
-
(2003)
Oncogene
, vol.22
, pp. 8983-8998
-
-
Franke, T.F.1
Hornik, C.P.2
Segev, L.3
Shostak, G.A.4
Sugimoto, C.5
-
30
-
-
77951623315
-
Regulation of survivin by PI3K/Akt/p70S6K1 pathway
-
10.1016/j.bbrc.2010.03.165, 20361940
-
Zhao P, Meng Q, Liu LZ, You YP, Liu N, Jiang BH. Regulation of survivin by PI3K/Akt/p70S6K1 pathway. Biochem Biophys Res Commun 2010, 395:219-224. 10.1016/j.bbrc.2010.03.165, 20361940.
-
(2010)
Biochem Biophys Res Commun
, vol.395
, pp. 219-224
-
-
Zhao, P.1
Meng, Q.2
Liu, L.Z.3
You, Y.P.4
Liu, N.5
Jiang, B.H.6
-
31
-
-
77950501014
-
MTOR regulation of autophagy
-
10.1016/j.febslet.2010.01.017, 2846630, 20083114
-
Jung CH, Ro SH, Cao J, Otto NM, Kim DH. mTOR regulation of autophagy. FEBS Lett 2010, 584:1287-1295. 10.1016/j.febslet.2010.01.017, 2846630, 20083114.
-
(2010)
FEBS Lett
, vol.584
, pp. 1287-1295
-
-
Jung, C.H.1
Ro, S.H.2
Cao, J.3
Otto, N.M.4
Kim, D.H.5
-
32
-
-
77951660067
-
Involvement of autophagy via mammalian target of rapamycin (mTOR) inhibition in tributyltin-induced neuronal cell death
-
10.2131/jts.35.245, 20371977
-
Nakatsu Y, Kotake Y, Takai N, Ohta S. Involvement of autophagy via mammalian target of rapamycin (mTOR) inhibition in tributyltin-induced neuronal cell death. J Toxicol Sci 2010, 35:245-251. 10.2131/jts.35.245, 20371977.
-
(2010)
J Toxicol Sci
, vol.35
, pp. 245-251
-
-
Nakatsu, Y.1
Kotake, Y.2
Takai, N.3
Ohta, S.4
-
33
-
-
71549161146
-
Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy
-
10.1158/0008-5472.CAN-09-2190, 2789206, 19920197
-
Fu L, Kim YA, Wang X, Wu X, Yue P, Lonial S, Khuri FR, Sun SY. Perifosine inhibits mammalian target of rapamycin signaling through facilitating degradation of major components in the mTOR axis and induces autophagy. Cancer Res 2009, 69:8967-8976. 10.1158/0008-5472.CAN-09-2190, 2789206, 19920197.
-
(2009)
Cancer Res
, vol.69
, pp. 8967-8976
-
-
Fu, L.1
Kim, Y.A.2
Wang, X.3
Wu, X.4
Yue, P.5
Lonial, S.6
Khuri, F.R.7
Sun, S.Y.8
|